SIMILAR PATTERNS OF AMINO ACIDS FOR 1DMA_A_NCAA700
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aor | ALDEHYDE FERREDOXINOXIDOREDUCTASE (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 4 | HIS A 412GLY A 411LEU A 406TYR A 410 | None | 0.72A | 1dmaA-1aorA:undetectable | 1dmaA-1aorA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1avg | TRIABIN (Meccuspallidipennis) |
PF03973(Triabin) | 4 | GLY I 30TYR I 58LEU I 27ALA I 28 | None | 0.84A | 1dmaA-1avgI:undetectable | 1dmaA-1avgI:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dtp | DIPHTHERIA TOXIN (Corynephagebeta) |
PF02763(Diphtheria_C) | 5 | HIS A 21GLY A 22ALA A 62TYR A 65GLU A 148 | APU A 200 ( 3.3A)APU A 200 ( 4.0A)APU A 200 ( 4.7A)APU A 200 ( 3.6A)None | 0.61A | 1dmaA-1dtpA:9.7 | 1dmaA-1dtpA:26.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dtp | DIPHTHERIA TOXIN (Corynephagebeta) |
PF02763(Diphtheria_C) | 5 | HIS A 21GLY A 22TYR A 54TYR A 65GLU A 148 | APU A 200 ( 3.3A)APU A 200 ( 4.0A)APU A 200 ( 4.0A)APU A 200 ( 3.6A)None | 0.46A | 1dmaA-1dtpA:9.7 | 1dmaA-1dtpA:26.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallus gallus) |
PF00644(PARP)PF02877(PARP_reg) | 5 | HIS A 862GLY A 863TYR A 896TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.51A | 1dmaA-1efyA:5.8 | 1dmaA-1efyA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1epv | ALANINE RACEMASE (Geobacillusstearothermophilus) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 45GLY A 44ALA A 42TYR A 43 | NoneNoneNoneDCS A1001 (-4.3A) | 0.87A | 1dmaA-1epvA:undetectable | 1dmaA-1epvA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhu | O-SUCCINYLBENZOATESYNTHASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 4 | GLY A 41TYR A 31ALA A 90GLU A 44 | None | 0.81A | 1dmaA-1fhuA:undetectable | 1dmaA-1fhuA:22.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ikp | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 6 | HIS A 440GLY A 441TYR A 470LEU A 477ALA A 478TYR A 481 | None | 0.29A | 1dmaA-1ikpA:33.1 | 1dmaA-1ikpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ikp | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 5 | TYR A 470LEU A 477ALA A 478TYR A 481GLU A 553 | None | 0.65A | 1dmaA-1ikpA:33.1 | 1dmaA-1ikpA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mor | GLUCOSAMINE6-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF01380(SIS) | 5 | GLY A 471TYR A 497LEU A 480ALA A 479TYR A 476 | None | 1.02A | 1dmaA-1morA:undetectable | 1dmaA-1morA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pix | GLUTACONYL-COADECARBOXYLASE ASUBUNIT (Acidaminococcusfermentans) |
PF01039(Carboxyl_trans) | 4 | GLY A 378TYR A 371ALA A 377GLU A 373 | None | 0.75A | 1dmaA-1pixA:undetectable | 1dmaA-1pixA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rc6 | HYPOTHETICAL PROTEINYLBA (Escherichiacoli) |
PF05899(Cupin_3)PF07883(Cupin_2) | 4 | GLY A1106LEU A1154ALA A1151TYR A1108 | None | 0.91A | 1dmaA-1rc6A:undetectable | 1dmaA-1rc6A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb8 | WBPP (Pseudomonasaeruginosa) |
PF01370(Epimerase) | 4 | HIS A 53GLY A 52ALA A 25GLU A 59 | NoneNAD A 342 (-2.9A)NAD A 342 (-4.2A)None | 0.81A | 1dmaA-1sb8A:undetectable | 1dmaA-1sb8A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vft | ALANINE RACEMASE (Streptomyceslavendulae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 44GLY A 43ALA A 41TYR A 42 | NoneNoneNoneDCS A 401 (-4.6A) | 0.83A | 1dmaA-1vftA:undetectable | 1dmaA-1vftA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdt | ELONGATION FACTOR GHOMOLOG (Thermusthermophilus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03764(EFG_IV)PF14492(EFG_II) | 4 | GLY A 481LEU A 550ALA A 551TYR A 470 | None | 0.85A | 1dmaA-1wdtA:undetectable | 1dmaA-1wdtA:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x5d | PROTEINDISULFIDE-ISOMERASEA6 (Homo sapiens) |
PF00085(Thioredoxin) | 4 | GLY A 80LEU A 75ALA A 76TYR A 79 | None | 0.91A | 1dmaA-1x5dA:undetectable | 1dmaA-1x5dA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7e | PROTEIN ARNA (Escherichiacoli) |
PF00551(Formyl_trans_N)PF01370(Epimerase)PF02911(Formyl_trans_C) | 4 | GLY A 612TYR A 398TYR A 613GLU A 434 | NoneUGA A1101 (-4.5A)NoneUGA A1101 (-4.0A) | 0.73A | 1dmaA-1z7eA:undetectable | 1dmaA-1z7eA:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bl5 | MGC83862 PROTEIN (Xenopus laevis) |
PF00013(KH_1) | 4 | GLY A 27LEU A 33ALA A 30GLU A 36 | None | 0.85A | 1dmaA-2bl5A:undetectable | 1dmaA-2bl5A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c0n | A197 (Sulfolobusturretedicosahedralvirus 1) |
no annotation | 4 | GLY A 149ALA A 138TYR A 153GLU A 42 | None | 0.88A | 1dmaA-2c0nA:undetectable | 1dmaA-2c0nA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c2l | CARBOXY TERMINUS OFHSP70-INTERACTINGPROTEIN (Mus musculus) |
PF04564(U-box)PF12895(ANAPC3) | 4 | LEU A 90ALA A 61TYR A 64GLU A 89 | None | 0.83A | 1dmaA-2c2lA:undetectable | 1dmaA-2c2lA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6h | GLUCOSAMINE-FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE (Escherichiacoli) |
PF01380(SIS)PF13522(GATase_6) | 4 | GLY A 471LEU A 480ALA A 479TYR A 476 | None | 0.84A | 1dmaA-2j6hA:undetectable | 1dmaA-2j6hA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nw0 | PLYB (unidentifiedphage) |
PF01183(Glyco_hydro_25) | 4 | TYR A 121ALA A 59TYR A 58GLU A 92 | ACT A1020 (-3.8A)NoneACT A1020 ( 3.9A)ACT A1020 (-3.8A) | 0.87A | 1dmaA-2nw0A:undetectable | 1dmaA-2nw0A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odo | ALANINE RACEMASE (Pseudomonasfluorescens) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 39GLY A 38ALA A 36TYR A 37 | NoneNoneNoneLLP A 33 ( 4.5A) | 0.88A | 1dmaA-2odoA:undetectable | 1dmaA-2odoA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqf | POLY [ADP-RIBOSE]POLYMERASE 12 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A 564GLY A 565TYR A 596TYR A 607 | GAB A 701 ( 3.7A)GAB A 701 (-3.6A)GAB A 701 (-4.5A)GAB A 701 (-3.3A) | 0.24A | 1dmaA-2pqfA:5.3 | 1dmaA-2pqfA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdd | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Roseovariusnubinhibens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 46TYR A 35ALA A 108GLU A 49 | None | 0.77A | 1dmaA-2qddA:undetectable | 1dmaA-2qddA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vd9 | ALANINE RACEMASE (Bacillusanthracis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 47GLY A 46ALA A 44TYR A 45 | NoneNoneNoneIN5 A1394 ( 4.4A) | 0.88A | 1dmaA-2vd9A:undetectable | 1dmaA-2vd9A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1c | ACYL-COENZYME (Penicilliumchrysogenum) |
PF03417(AAT) | 4 | GLY A 102LEU A 169ALA A 168GLU A 258 | None | 0.77A | 1dmaA-2x1cA:undetectable | 1dmaA-2x1cA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yr5 | PRO-ENZYME OFL-PHENYLALANINEOXIDASE (Pseudomonas sp.P-501) |
no annotation | 4 | GLY A 67TYR A 73LEU A 669ALA A 668 | FAD A 801 (-3.4A)NoneNoneNone | 0.73A | 1dmaA-2yr5A:undetectable | 1dmaA-2yr5A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzr | UNSATURATEDGLUCURONYL HYDROLASE (Streptococcusagalactiae) |
PF07470(Glyco_hydro_88) | 4 | GLY A 371ALA A 55TYR A 364GLU A 68 | None | 0.88A | 1dmaA-2zzrA:undetectable | 1dmaA-2zzrA:21.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b78 | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly) | 7 | HIS B 440GLY B 441TYR B 470LEU B 477ALA B 478TYR B 481GLU B 553 | NAD B 700 (-3.9A)NAD B 700 (-3.9A)NAD B 700 (-3.9A)NAD B 700 ( 4.8A)NAD B 700 (-3.6A)NAD B 700 (-3.4A)NAD B 700 (-3.5A) | 0.34A | 1dmaA-3b78B:33.1 | 1dmaA-3b78B:99.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c49 | POLY(ADP-RIBOSE)POLYMERASE 3 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg) | 4 | HIS A 384GLY A 385TYR A 414TYR A 425 | KU8 A 601 (-4.0A)KU8 A 601 (-3.5A)KU8 A 601 (-4.1A)KU8 A 601 (-3.5A) | 0.37A | 1dmaA-3c49A:5.9 | 1dmaA-3c49A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c49 | POLY(ADP-RIBOSE)POLYMERASE 3 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg) | 4 | HIS A 384TYR A 414TYR A 425GLU A 514 | KU8 A 601 (-4.0A)KU8 A 601 (-4.1A)KU8 A 601 (-3.5A)KU8 A 601 (-3.9A) | 0.66A | 1dmaA-3c49A:5.9 | 1dmaA-3c49A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8e | YGHU, GLUTATHIONES-TRANSFERASEHOMOLOGUE (Escherichiacoli) |
PF02798(GST_N)PF13410(GST_C_2) | 4 | GLY A 222TYR A 225LEU A 231ALA A 228 | None | 0.78A | 1dmaA-3c8eA:undetectable | 1dmaA-3c8eA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cea | MYO-INOSITOL2-DEHYDROGENASE (Lactobacillusplantarum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLY A 14TYR A 62LEU A 41ALA A 40 | NAD A 400 (-3.3A)NoneNAD A 400 (-4.2A)NAD A 400 (-3.6A) | 0.91A | 1dmaA-3ceaA:undetectable | 1dmaA-3ceaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gc2 | O-SUCCINYLBENZOATESYNTHASE (Salmonellaenterica) |
PF13378(MR_MLE_C) | 4 | GLY A 41TYR A 31ALA A 90GLU A 44 | SIN A 401 ( 4.7A)NoneNoneNone | 0.78A | 1dmaA-3gc2A:undetectable | 1dmaA-3gc2A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7v | O-SUCCINYLBENZOATESYNTHASE (Thermosynechococcuselongatus) |
PF13378(MR_MLE_C) | 4 | GLY A 41TYR A 30ALA A 92GLU A 44 | None | 0.80A | 1dmaA-3h7vA:undetectable | 1dmaA-3h7vA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkv | POLY [ADP-RIBOSE]POLYMERASE 10 (Homo sapiens) |
PF00644(PARP) | 5 | HIS A 887GLY A 888TYR A 919LEU A 926TYR A 932 | 3AB A1025 (-3.8A)3AB A1025 (-3.5A)3AB A1025 (-4.4A)3AB A1025 (-4.4A)3AB A1025 (-3.7A) | 0.33A | 1dmaA-3hkvA:5.5 | 1dmaA-3hkvA:25.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmc | PUTATIVE PROPHAGELAMBDABA04, GLYCOSYLHYDROLASE, FAMILY 25 (Bacillusanthracis) |
PF01183(Glyco_hydro_25) | 4 | TYR A 124ALA A 62TYR A 61GLU A 95 | MES A 400 (-3.6A)NoneMES A 400 (-4.0A)MES A 400 (-3.5A) | 0.76A | 1dmaA-3hmcA:undetectable | 1dmaA-3hmcA:24.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jup | PHENAZINEBIOSYNTHESIS PROTEINA/B (Burkholderialata) |
PF03284(PHZA_PHZB) | 4 | HIS A 42GLY A 71LEU A 78ALA A 74 | None | 0.87A | 1dmaA-3jupA:undetectable | 1dmaA-3jupA:21.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ki6 | CHOLIX TOXIN (Vibrio cholerae) |
PF09009(Exotox-A_cataly) | 6 | HIS A 460GLY A 461TYR A 493ALA A 501TYR A 504GLU A 581 | G9L A 1 (-3.9A)G9L A 1 (-3.7A)G9L A 1 (-4.5A)G9L A 1 (-3.4A)G9L A 1 (-3.5A)G9L A 1 (-4.6A) | 0.27A | 1dmaA-3ki6A:25.3 | 1dmaA-3ki6A:40.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nnk | UREIDOGLYCINE-GLYOXYLATEAMINOTRANSFERASE (Klebsiellapneumoniae) |
PF00266(Aminotran_5) | 4 | GLY A 335LEU A 341ALA A 338GLU A 344 | None | 0.82A | 1dmaA-3nnkA:undetectable | 1dmaA-3nnkA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9o | EXOTOXIN A (Vibrio cholerae) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 6 | HIS A 460GLY A 461TYR A 493ALA A 501TYR A 504GLU A 581 | NAD A 700 (-3.8A)NAD A 700 (-3.7A)NAD A 700 ( 3.7A)NAD A 700 (-3.5A)NAD A 700 (-3.4A)NAD A 700 (-3.2A) | 0.36A | 1dmaA-3q9oA:24.9 | 1dmaA-3q9oA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rb9 | DNA POLYMERASE IIISUBUNIT BETA (Mycobacteriumtuberculosis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | GLY A 304ALA A 302TYR A 326GLU A 329 | None | 0.90A | 1dmaA-3rb9A:undetectable | 1dmaA-3rb9A:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ruc | WBGU (Plesiomonasshigelloides) |
PF01370(Epimerase) | 4 | HIS A 53GLY A 52ALA A 25GLU A 59 | NoneNAD A 343 (-3.0A)NAD A 343 (-4.3A)None | 0.74A | 1dmaA-3rucA:undetectable | 1dmaA-3rucA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s46 | ALANINE RACEMASE (Streptococcuspneumoniae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 46GLY A 45ALA A 43TYR A 44 | NoneNoneNoneLLP A 40 ( 4.6A) | 0.92A | 1dmaA-3s46A:undetectable | 1dmaA-3s46A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqp | ENOLASE (Coxiellaburnetii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLY A 34LEU A 117ALA A 118TYR A 121 | None | 0.73A | 1dmaA-3tqpA:undetectable | 1dmaA-3tqpA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqp | ENOLASE (Coxiellaburnetii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLY A 360ALA A 333TYR A 359GLU A 304 | None | 0.82A | 1dmaA-3tqpA:undetectable | 1dmaA-3tqpA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3urh | DIHYDROLIPOYLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | GLY A 9TYR A 15ALA A 142GLU A 327 | FAD A 500 (-3.2A)NoneFAD A 500 (-4.8A)None | 0.87A | 1dmaA-3urhA:undetectable | 1dmaA-3urhA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vr5 | V-TYPE SODIUM ATPASESUBUNIT B (Enterococcushirae) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 4 | HIS D 242GLY D 296LEU D 235ALA D 236 | None | 0.85A | 1dmaA-3vr5D:undetectable | 1dmaA-3vr5D:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zfv | CRISPR-ASSOCIATEDENDORIBONUCLEASECAS6 1 (Sulfolobussolfataricus) |
PF10040(CRISPR_Cas6) | 4 | LEU A 258ALA A 259TYR A 262GLU A 127 | None | 0.75A | 1dmaA-3zfvA:undetectable | 1dmaA-3zfvA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a39 | METALLO-CARBOXYPEPTIDASE (Pseudomonasaeruginosa) |
PF00246(Peptidase_M14) | 4 | HIS A 40GLY A 10ALA A 5GLU A 44 | None | 0.75A | 1dmaA-4a39A:undetectable | 1dmaA-4a39A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ae0 | DIPHTHERIA TOXIN (Corynebacteriumdiphtheriae) |
PF01324(Diphtheria_R)PF02763(Diphtheria_C)PF02764(Diphtheria_T) | 5 | HIS A 21GLY A 22TYR A 54ALA A 62TYR A 65 | None | 0.63A | 1dmaA-4ae0A:9.7 | 1dmaA-4ae0A:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ae0 | DIPHTHERIA TOXIN (Corynebacteriumdiphtheriae) |
PF01324(Diphtheria_R)PF02763(Diphtheria_C)PF02764(Diphtheria_T) | 4 | TYR A 54ALA A 62TYR A 65GLU A 148 | None | 0.79A | 1dmaA-4ae0A:9.7 | 1dmaA-4ae0A:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bk1 | PROBABLE SALICYLATEMONOOXYGENASE (Rhodococcusjostii) |
PF01494(FAD_binding_3) | 4 | HIS A 53GLY A 51LEU A 58ALA A 55 | None | 0.85A | 1dmaA-4bk1A:undetectable | 1dmaA-4bk1A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3o | HYDROGENASE-1 LARGESUBUNIT (Salmonellaenterica) |
PF00374(NiFeSe_Hases) | 4 | GLY A 305LEU A 302ALA A 303TYR A 304 | None | 0.88A | 1dmaA-4c3oA:undetectable | 1dmaA-4c3oA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccl | 50S RIBOSOMALPROTEIN L16 ARGININEHYDROXYLASE (Escherichiacoli) |
PF08007(Cupin_4) | 4 | GLY A 120LEU A 192ALA A 191TYR A 190 | None | 0.77A | 1dmaA-4cclA:undetectable | 1dmaA-4cclA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dza | LYSINE RACEMASE (Proteusmirabilis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 80GLY A 79ALA A 77TYR A 78 | NoneNoneNoneLLP A 74 ( 4.4A) | 0.87A | 1dmaA-4dzaA:undetectable | 1dmaA-4dzaA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4f | MANNONATEDEHYDRATASE (Pectobacteriumcarotovorum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 380ALA A 381TYR A 384GLU A 351 | None | 0.58A | 1dmaA-4e4fA:undetectable | 1dmaA-4e4fA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4el8 | GLYCOSIDE HYDROLASEFAMILY 48 (Caldicellulosiruptorbescii) |
PF02011(Glyco_hydro_48) | 4 | GLY A 289LEU A 133TYR A 290GLU A 136 | None | 0.93A | 1dmaA-4el8A:undetectable | 1dmaA-4el8A:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eyg | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNAL (Rhodopseudomonaspalustris) |
PF13458(Peripla_BP_6) | 4 | GLY A 309LEU A 56ALA A 53TYR A 310 | NoneNoneNoneEDO A 402 (-4.5A) | 0.81A | 1dmaA-4eygA:undetectable | 1dmaA-4eygA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0d | POLY [ADP-RIBOSE]POLYMERASE 16 (Homo sapiens) |
PF00644(PARP) | 6 | HIS A 152GLY A 153TYR A 182LEU A 189ALA A 190TYR A 193 | 3AB A 301 (-4.0A)3AB A 301 (-3.4A)3AB A 301 (-4.3A)3AB A 301 ( 4.7A)3AB A 301 (-3.9A)3AB A 301 (-3.8A) | 0.37A | 1dmaA-4f0dA:4.7 | 1dmaA-4f0dA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0e | POLY [ADP-RIBOSE]POLYMERASE 15 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A 537GLY A 538TYR A 569TYR A 582 | 0RU A 701 (-3.7A)0RU A 701 (-3.3A)0RU A 701 (-4.3A)0RU A 701 (-3.7A) | 0.30A | 1dmaA-4f0eA:5.1 | 1dmaA-4f0eA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ff5 | GLYCOSYL HYDROLASE25 (Streptococcuspneumoniae) |
PF01183(Glyco_hydro_25) | 4 | TYR A 162ALA A 99TYR A 98GLU A 133 | None | 0.81A | 1dmaA-4ff5A:undetectable | 1dmaA-4ff5A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ihc | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Dickeyaparadisiaca) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 391ALA A 392TYR A 395GLU A 362 | None | 0.66A | 1dmaA-4ihcA:undetectable | 1dmaA-4ihcA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jeg | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 11 (Homo sapiens) |
PF00017(SH2) | 4 | GLY A 119LEU A 125ALA A 122GLU A 128 | None | 0.90A | 1dmaA-4jegA:undetectable | 1dmaA-4jegA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l2k | TANKYRASE-2 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A1031GLY A1032TYR A1060TYR A1071 | 1V8 A1201 (-4.2A)1V8 A1201 (-3.7A)1V8 A1201 (-4.7A)1V8 A1201 (-3.3A) | 0.21A | 1dmaA-4l2kA:2.8 | 1dmaA-4l2kA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lut | ALANINE RACEMASE (Clostridioidesdifficile) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 45GLY A 44ALA A 42TYR A 43 | NoneNoneNoneDCS A 401 (-4.6A) | 0.90A | 1dmaA-4lutA:undetectable | 1dmaA-4lutA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnm | CHITINASE A (Cycas revoluta) |
PF00704(Glyco_hydro_18) | 4 | GLY A 110TYR A 32LEU A 105TYR A 109 | None | 0.87A | 1dmaA-4mnmA:undetectable | 1dmaA-4mnmA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mpt | PUTATIVELEU/ILE/VAL-BINDINGPROTEIN (Bordetellapertussis) |
PF13458(Peripla_BP_6) | 4 | GLY A 304LEU A 29ALA A 26TYR A 305 | None | 0.87A | 1dmaA-4mptA:undetectable | 1dmaA-4mptA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n03 | ABC-TYPEBRANCHED-CHAIN AMINOACID TRANSPORTSYSTEMS PERIPLASMICCOMPONENT-LIKEPROTEIN (Thermomonosporacurvata) |
PF13458(Peripla_BP_6) | 4 | GLY A 332LEU A 77ALA A 74TYR A 333 | None | 0.83A | 1dmaA-4n03A:undetectable | 1dmaA-4n03A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oa7 | TANKYRASE-1 (Homo sapiens) |
PF00644(PARP) | 5 | HIS A1184GLY A1185TYR A1213TYR A1224GLU A1291 | 2XS A1402 (-4.2A)None2XS A1402 (-4.2A)2XS A1402 ( 3.9A)None | 0.61A | 1dmaA-4oa7A:6.0 | 1dmaA-4oa7A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqa | POLY [ADP-RIBOSE]POLYMERASE 1 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg)PF05406(WGR) | 5 | HIS C 862GLY C 863TYR C 896TYR C 907GLU C 988 | 2US C1101 (-3.7A)2US C1101 (-3.3A)2US C1101 (-4.2A)2US C1101 (-3.5A)2US C1101 (-3.2A) | 0.52A | 1dmaA-4oqaC:5.4 | 1dmaA-4oqaC:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pua | GLUTATHIONES-TRANSFERASE (Streptococcuspneumoniae) |
PF02798(GST_N)PF13410(GST_C_2) | 4 | GLY A 220TYR A 223LEU A 230ALA A 227 | None | 0.86A | 1dmaA-4puaA:undetectable | 1dmaA-4puaA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4py4 | POLY [ADP-RIBOSE]POLYMERASE 14 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A1682GLY A1683TYR A1714TYR A1727 | XL2 A1901 (-4.0A)XL2 A1901 (-3.6A)XL2 A1901 (-3.7A)XL2 A1901 (-3.6A) | 0.16A | 1dmaA-4py4A:5.6 | 1dmaA-4py4A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qhr | ALANINE RACEMASE (Acinetobacterbaumannii) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 40GLY A 39ALA A 37TYR A 38 | NoneNoneNoneLLP A 34 ( 4.5A) | 0.89A | 1dmaA-4qhrA:undetectable | 1dmaA-4qhrA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w65 | GLYCOSYL HYDROLASEFAMILY PROTEIN (Mycolicibacteriumfortuitum) |
PF00722(Glyco_hydro_16) | 4 | GLY A 149TYR A 170ALA A 150GLU A 168 | GLY A 149 ( 0.0A)TYR A 170 ( 1.3A)ALA A 150 ( 0.0A)GLU A 168 (-0.5A) | 0.90A | 1dmaA-4w65A:undetectable | 1dmaA-4w65A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wgg | DOUBLE BONDREDUCTASE (Zingiberofficinale) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 4 | GLY A 254TYR A 234LEU A 286GLU A 236 | None | 0.82A | 1dmaA-4wggA:undetectable | 1dmaA-4wggA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr3 | ALANINE RACEMASE,BIOSYNTHETIC (Escherichiacoli) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 40GLY A 39ALA A 37TYR A 38 | NoneNoneNonePLP A1001 (-4.4A) | 0.88A | 1dmaA-4wr3A:undetectable | 1dmaA-4wr3A:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8k | RNA POLYMERASE SIGMAFACTOR SIGA (Mycobacteriumtuberculosis) |
PF00140(Sigma70_r1_2)PF04542(Sigma70_r2) | 4 | GLY A 256ALA A 259TYR A 258GLU A 265 | None | 0.92A | 1dmaA-4x8kA:undetectable | 1dmaA-4x8kA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xdq | GLYCOSIDE HYDROLASEFAMILY PROTEIN (Mycolicibacteriumthermoresistibile) |
PF00722(Glyco_hydro_16) | 4 | GLY A 126TYR A 150ALA A 127GLU A 148 | NoneNoneNoneEDO A 307 (-3.4A) | 0.88A | 1dmaA-4xdqA:undetectable | 1dmaA-4xdqA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z2a | FURIN (Homo sapiens) |
PF00082(Peptidase_S8)PF01483(P_proprotein) | 4 | GLY A 427LEU A 337ALA A 338TYR A 426 | None | 0.91A | 1dmaA-4z2aA:undetectable | 1dmaA-4z2aA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzy | POLY [ADP-RIBOSE]POLYMERASE 2 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg) | 4 | HIS A 428GLY A 429TYR A 462TYR A 473 | D7N A1584 (-3.6A)D7N A1584 (-3.8A)D7N A1584 (-3.7A)D7N A1584 (-3.8A) | 0.41A | 1dmaA-4zzyA:6.0 | 1dmaA-4zzyA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzy | POLY [ADP-RIBOSE]POLYMERASE 2 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg) | 4 | HIS A 428GLY A 429TYR A 473GLU A 558 | D7N A1584 (-3.6A)D7N A1584 (-3.8A)D7N A1584 (-3.8A)D7N A1584 (-3.9A) | 0.53A | 1dmaA-4zzyA:6.0 | 1dmaA-4zzyA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dcz | TANKYRASE-2 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A1031GLY A1032TYR A1060TYR A1071 | 59B A1203 (-4.1A)59B A1203 (-4.1A)59B A1203 (-4.3A)59B A1203 (-3.3A) | 0.16A | 1dmaA-5dczA:6.1 | 1dmaA-5dczA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dcz | TANKYRASE-2 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A1031GLY A1032TYR A1071GLU A1138 | 59B A1203 (-4.1A)59B A1203 (-4.1A)59B A1203 (-3.3A)59B A1203 (-3.7A) | 0.75A | 1dmaA-5dczA:6.1 | 1dmaA-5dczA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dsy | POLY [ADP-RIBOSE]POLYMERASE 2 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A 415GLY A 416TYR A 449TYR A 460 | UHB A1001 (-3.7A)UHB A1001 (-3.9A)UHB A1001 (-3.8A)UHB A1001 (-3.4A) | 0.31A | 1dmaA-5dsyA:5.8 | 1dmaA-5dsyA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dsy | POLY [ADP-RIBOSE]POLYMERASE 2 (Homo sapiens) |
PF00644(PARP) | 4 | HIS A 415GLY A 416TYR A 460GLU A 545 | UHB A1001 (-3.7A)UHB A1001 (-3.9A)UHB A1001 (-3.4A)UHB A1001 (-3.5A) | 0.52A | 1dmaA-5dsyA:5.8 | 1dmaA-5dsyA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eu0 | ANTITOXIN 1 (Bartonellarochalimae) |
no annotation | 4 | GLY B 47ALA B 49TYR B 48GLU B 15 | None | 0.92A | 1dmaA-5eu0B:undetectable | 1dmaA-5eu0B:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fac | ALANINE RACEMASE (Streptomycescoelicolor) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | HIS A 52GLY A 51ALA A 49TYR A 50 | NoneNoneNonePLP A 401 (-4.6A) | 0.91A | 1dmaA-5facA:undetectable | 1dmaA-5facA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq1 | HISTIDINE KINASE (Geobacillusthermodenitrificans) |
PF13426(PAS_9) | 4 | GLY A 220LEU A 238ALA A 237GLU A 246 | NoneNoneNoneGOL A1310 ( 3.9A) | 0.86A | 1dmaA-5fq1A:undetectable | 1dmaA-5fq1A:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ghs | SSDNA-SPECIFICEXONUCLEASE (Thermococcuskodakarensis) |
PF02272(DHHA1) | 4 | GLY A 314TYR A 325ALA A 316GLU A 322 | None | 0.88A | 1dmaA-5ghsA:undetectable | 1dmaA-5ghsA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2l | NAB2P (Saccharomycescerevisiae) |
PF14608(zf-CCCH_2) | 4 | HIS A 430GLY A 418TYR A 428GLU A 413 | ZN A 501 (-3.3A)None A G 3 ( 3.9A) ZN A 504 (-2.6A) | 0.71A | 1dmaA-5l2lA:undetectable | 1dmaA-5l2lA:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lx6 | POLY [ADP-RIBOSE]POLYMERASE 10 (Homo sapiens) |
PF00644(PARP) | 5 | HIS A 887GLY A 888TYR A 919LEU A 926TYR A 932 | 78P A1101 (-4.0A)78P A1101 (-3.7A)78P A1101 (-3.7A)78P A1101 ( 4.6A)78P A1101 (-3.8A) | 0.43A | 1dmaA-5lx6A:4.8 | 1dmaA-5lx6A:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdm | GLYCOPROTEIN (Chandipuravesiculovirus) |
no annotation | 4 | GLY E 200TYR E 191LEU E 252ALA E 199 | None | 0.72A | 1dmaA-5mdmE:undetectable | 1dmaA-5mdmE:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nh2 | UNCHARACTERIZEDPROTEIN (Bartonellahenselae) |
no annotation | 4 | GLY B 49ALA B 51TYR B 50GLU B 17 | GLY B 49 ( 0.0A)ALA B 51 ( 0.0A)TYR B 50 ( 1.3A)GLU B 17 ( 0.5A) | 0.85A | 1dmaA-5nh2B:undetectable | 1dmaA-5nh2B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xoe | ATP-DEPENDENT6-PHOSPHOFRUCTOKINASE (Staphylococcusaureus) |
no annotation | 4 | GLY A 271ALA A 273TYR A 272GLU A 281 | None | 0.85A | 1dmaA-5xoeA:undetectable | 1dmaA-5xoeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xst | POLY [ADP-RIBOSE]POLYMERASE 1 (Homo sapiens) |
no annotation | 5 | HIS A 201GLY A 202TYR A 235TYR A 246GLU A 327 | 8E6 A 401 (-3.5A)8E6 A 401 (-3.9A)8E6 A 401 (-4.1A)8E6 A 401 (-3.4A)8E6 A 401 (-3.9A) | 0.46A | 1dmaA-5xstA:6.0 | 1dmaA-5xstA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y58 | ATP-DEPENDENT DNAHELICASE II SUBUNIT1 (Saccharomycescerevisiae) |
no annotation | 4 | GLY A 93TYR A 81ALA A 90GLU A 96 | None | 0.87A | 1dmaA-5y58A:undetectable | 1dmaA-5y58A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a2f | - (-) |
no annotation | 4 | HIS A 40GLY A 39ALA A 37TYR A 38 | NoneNoneNoneLLP A 34 ( 4.5A) | 0.91A | 1dmaA-6a2fA:undetectable | 1dmaA-6a2fA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bhv | POLY [ADP-RIBOSE]POLYMERASE 1 (Homo sapiens) |
no annotation | 5 | HIS A 862GLY A 863TYR A 896TYR A 907GLU A 988 | DQV A1101 (-3.6A)DQV A1101 (-3.8A)DQV A1101 (-3.5A)DQV A1101 (-3.7A)DQV A1101 (-3.3A) | 0.45A | 1dmaA-6bhvA:6.0 | 1dmaA-6bhvA:undetectable |