SIMILAR PATTERNS OF AMINO ACIDS FOR 1DED_A_QPSA2001
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cyg | CYCLODEXTRINGLUCANOTRANSFERASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 5 | TRP A 609LYS A 644TRP A 656GLY A 659ASN A 661 | None | 0.98A | 1dedA-1cygA:60.4 | 1dedA-1cygA:63.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i71 | APOLIPOPROTEIN(A) (Homo sapiens) |
PF00051(Kringle) | 4 | TRP A 25GLY A 43ASN A 52PRO A 41 | None | 1.27A | 1dedA-1i71A:undetectable | 1dedA-1i71A:9.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jfr | LIPASE (Streptomycesexfoliatus) |
PF03403(PAF-AH_p_II) | 4 | TRP A 162GLY A 133ASN A 157PRO A 61 | None | 1.48A | 1dedA-1jfrA:undetectable | 1dedA-1jfrA:18.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kcl | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | TRP A 616LYS A 651GLY A 665ASN A 667 | GLC A1699 (-3.8A)GLC A1698 (-2.5A)NoneGLC A1699 (-2.8A) | 1.01A | 1dedA-1kclA:64.3 | 1dedA-1kclA:88.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kcl | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 6 | TRP A 616LYS A 651TRP A 662GLY A 664ASN A 667PRO A 686 | GLC A1699 (-3.8A)GLC A1698 (-2.5A)GLC A1698 ( 3.8A)GLC A1698 ( 4.8A)GLC A1699 (-2.8A)None | 0.45A | 1dedA-1kclA:64.3 | 1dedA-1kclA:88.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odu | PUTATIVEALPHA-L-FUCOSIDASE (Thermotogamaritima) |
PF01120(Alpha_L_fucos) | 4 | TRP A 227GLY A 256ASN A 252PRO A 258 | None | 1.39A | 1dedA-1oduA:11.5 | 1dedA-1oduA:20.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qho | ALPHA-AMYLASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | TRP A 612LYS A 650GLY A 665ASN A 667 | MAL A1201 (-3.8A)MAL A1201 (-2.7A)NoneMAL A1201 (-3.0A) | 1.04A | 1dedA-1qhoA:56.0 | 1dedA-1qhoA:45.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qho | ALPHA-AMYLASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | TRP A 612LYS A 650TRP A 662ASN A 667 | MAL A1201 (-3.8A)MAL A1201 (-2.7A)MAL A1201 (-3.7A)MAL A1201 (-3.0A) | 0.29A | 1dedA-1qhoA:56.0 | 1dedA-1qhoA:45.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tyd | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 4 | TRP E 97GLY E 77ASN E 89PRO E 79 | None | 1.21A | 1dedA-1tydE:undetectable | 1dedA-1tydE:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uv4 | ARABINAN-ENDO1,5-ALPHA-L-ARABINASE (Bacillussubtilis) |
PF04616(Glyco_hydro_43) | 4 | TRP A 152GLY A 181ASN A 210PRO A 178 | None | 1.01A | 1dedA-1uv4A:undetectable | 1dedA-1uv4A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uv4 | ARABINAN-ENDO1,5-ALPHA-L-ARABINASE (Bacillussubtilis) |
PF04616(Glyco_hydro_43) | 4 | TRP A 152GLY A 182ASN A 210PRO A 178 | None | 1.40A | 1dedA-1uv4A:undetectable | 1dedA-1uv4A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbm | TYROSYL-TRNASYNTHETASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 4 | TRP A 100GLY A 80ASN A 92PRO A 82 | None | 1.19A | 1dedA-1vbmA:undetectable | 1dedA-1vbmA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z0n | 5'-AMP-ACTIVATEDPROTEIN KINASE,BETA-1 SUBUNIT (Rattusnorvegicus) |
PF16561(AMPK1_CBM) | 4 | TRP A 100LYS A 126TRP A 133ASN A 150 | BCD A1200 (-3.8A)BCD A1200 (-2.7A)BCD A1200 ( 3.9A)BCD A1200 (-3.0A) | 0.40A | 1dedA-1z0nA:8.5 | 1dedA-1z0nA:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f15 | 5'-AMP-ACTIVATEDPROTEIN KINASE,BETA-2 SUBUNIT (Homo sapiens) |
PF16561(AMPK1_CBM) | 4 | TRP A 99LYS A 126TRP A 133ASN A 150 | None | 0.67A | 1dedA-2f15A:8.2 | 1dedA-2f15A:9.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f4p | HYPOTHETICAL PROTEINTM1010 (Thermotogamaritima) |
PF07883(Cupin_2) | 4 | TRP A 22GLY A 46ASN A 20PRO A 99 | None | 1.19A | 1dedA-2f4pA:2.1 | 1dedA-2f4pA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2frv | PERIPLASMICHYDROGENASE (Desulfovibriogigas) |
no annotation | 4 | TRP L 36GLY L 508ASN L 34PRO L 510 | None | 1.34A | 1dedA-2frvL:undetectable | 1dedA-2frvL:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gpc | IRON SUPEROXIDEDISMUTASE (Trypanosomacruzi) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 162GLY A 145ASN A 67PRO A 147 | None | 1.26A | 1dedA-2gpcA:undetectable | 1dedA-2gpcA:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwn | DIHYDROOROTASE (Porphyromonasgingivalis) |
PF01979(Amidohydro_1) | 4 | LYS A 322GLY A 332ASN A 281PRO A 316 | None | 1.15A | 1dedA-2gwnA:3.3 | 1dedA-2gwnA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gy7 | ANGIOPOIETIN-2 (Homo sapiens) |
PF00147(Fibrinogen_C) | 4 | TRP A 354TRP A 446ASN A 456PRO A 452 | None | 1.12A | 1dedA-2gy7A:undetectable | 1dedA-2gy7A:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ts1 | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 4 | TRP A 97GLY A 77ASN A 89PRO A 79 | None | 1.24A | 1dedA-2ts1A:undetectable | 1dedA-2ts1A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vc2 | INTEGRIN ALPHA-IIB (Homo sapiens) |
PF01839(FG-GAP)PF13517(VCBS) | 4 | TRP A 262GLY A 233ASN A 227PRO A 258 | None | 1.44A | 1dedA-2vc2A:undetectable | 1dedA-2vc2A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vn7 | GLUCOAMYLASE (Trichodermareesei) |
PF00686(CBM_20)PF00723(Glyco_hydro_15) | 4 | TRP A 525LYS A 560TRP A 572ASN A 577 | None | 0.39A | 1dedA-2vn7A:11.7 | 1dedA-2vn7A:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wan | PULLULANASE (Bacillusacidopullulyticus) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | TRP A 182LYS A 213GLY A 226ASN A 228 | None | 1.21A | 1dedA-2wanA:28.0 | 1dedA-2wanA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wan | PULLULANASE (Bacillusacidopullulyticus) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | TRP A 182LYS A 213TRP A 220ASN A 228 | None | 1.23A | 1dedA-2wanA:28.0 | 1dedA-2wanA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wmh | FUCOLECTIN-RELATEDPROTEIN (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 4 | TRP A 62GLY A 54ASN A 57PRO A 88 | None | 0.78A | 1dedA-2wmhA:9.3 | 1dedA-2wmhA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yx0 | RADICAL SAM ENZYME (Pyrococcushorikoshii) |
PF04055(Radical_SAM)PF08608(Wyosine_form) | 4 | TRP A 222GLY A 221ASN A 214PRO A 219 | None | 1.23A | 1dedA-2yx0A:undetectable | 1dedA-2yx0A:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzr | UNSATURATEDGLUCURONYL HYDROLASE (Streptococcusagalactiae) |
PF07470(Glyco_hydro_88) | 4 | TRP A 251GLY A 255ASN A 179PRO A 257 | None | 1.40A | 1dedA-2zzrA:undetectable | 1dedA-2zzrA:20.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bmw | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Thermoanaerobacteriumthermosulfurigenes) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | TRP A 613LYS A 648GLY A 662ASN A 664 | None | 1.06A | 1dedA-3bmwA:61.0 | 1dedA-3bmwA:68.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bmw | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Thermoanaerobacteriumthermosulfurigenes) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | TRP A 613LYS A 648TRP A 659GLY A 661ASN A 664 | None | 0.46A | 1dedA-3bmwA:61.0 | 1dedA-3bmwA:68.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3esf | IRON-CONTAININGSUPEROXIDE DISMUTASEB2 (Trypanosomabrucei) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 163GLY A 146ASN A 68PRO A 148 | None | 1.24A | 1dedA-3esfA:undetectable | 1dedA-3esfA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1s | SUPEROXIDE DISMUTASE (Francisellatularensis) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 158GLY A 142ASN A 66PRO A 144 | None | 1.23A | 1dedA-3h1sA:undetectable | 1dedA-3h1sA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjh | TRANSCRIPTION-REPAIR-COUPLING FACTOR (Escherichiacoli) |
no annotation | 4 | TRP A 321TRP A 73GLY A 256PRO A 254 | None | 1.36A | 1dedA-3hjhA:undetectable | 1dedA-3hjhA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3led | 3-OXOACYL-ACYLCARRIER PROTEINSYNTHASE III (Rhodopseudomonaspalustris) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LYS A 255GLY A 249ASN A 238PRO A 247 | None | 1.23A | 1dedA-3ledA:undetectable | 1dedA-3ledA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nap | CAPSID PROTEIN (Triatoma virus) |
PF00073(Rhv)PF08762(CRPV_capsid) | 4 | LYS A 120GLY C 29ASN A 57PRO C 31 | None | 1.35A | 1dedA-3napA:undetectable | 1dedA-3napA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nt8 | ANCYLOSTOMA SECRETEDPROTEIN 1 (Necatoramericanus) |
PF00188(CAP) | 4 | TRP A 127GLY A 125ASN A 102PRO A 121 | None | 1.30A | 1dedA-3nt8A:undetectable | 1dedA-3nt8A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ros | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Lactobacillusacidophilus) |
PF00171(Aldedh) | 4 | TRP A 418GLY A 260ASN A 132PRO A 364 | None | 1.16A | 1dedA-3rosA:undetectable | 1dedA-3rosA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3whe | HEMAGGLUTININIMMUNOGLOBULIN HEAVYCHAIN (Homo sapiens;Influenza Avirus) |
PF00509(Hemagglutinin)no annotation | 4 | TRP M 50GLY M 104ASN M 52PRO A 284 | NoneNAG A 601 (-3.6A)NoneNone | 1.38A | 1dedA-3wheM:3.5 | 1dedA-3wheM:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxl | HIAXHD3 (Humicolainsolens) |
PF04616(Glyco_hydro_43) | 4 | TRP A 134GLY A 65ASN A 362PRO A 67 | None | 1.11A | 1dedA-3zxlA:undetectable | 1dedA-3zxlA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | TRP A 352GLY A 345ASN A 180PRO A 347 | None | 1.36A | 1dedA-4bedA:undetectable | 1dedA-4bedA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bvw | APOLIPOPROTEIN(A) (Homo sapiens) |
PF00051(Kringle) | 4 | TRP A 25GLY A 43ASN A 52PRO A 41 | None | 1.29A | 1dedA-4bvwA:undetectable | 1dedA-4bvwA:9.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4cgt | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | TRP A 614LYS A 650GLY A 664ASN A 666 | None | 1.11A | 1dedA-4cgtA:60.1 | 1dedA-4cgtA:72.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4cgt | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | TRP A 614LYS A 650TRP A 661ASN A 666 | None | 0.47A | 1dedA-4cgtA:60.1 | 1dedA-4cgtA:72.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvh | SUPEROXIDE DISMUTASE (Trypanosomacruzi) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 165GLY A 149ASN A 71PRO A 151 | None | 1.15A | 1dedA-4dvhA:undetectable | 1dedA-4dvhA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4epu | ANGIOPOIETIN-1 (Homo sapiens) |
PF00147(Fibrinogen_C) | 4 | TRP A 356TRP A 448ASN A 458PRO A 454 | None | 1.21A | 1dedA-4epuA:undetectable | 1dedA-4epuA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f2n | SUPEROXIDE DISMUTASE (Leishmaniamajor) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 193GLY A 177ASN A 100PRO A 179 | None | 1.21A | 1dedA-4f2nA:undetectable | 1dedA-4f2nA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3e | CASA (Thermusthermophilus) |
PF09481(CRISPR_Cse1) | 4 | TRP A 77GLY A 81ASN A 194PRO A 83 | None | 1.26A | 1dedA-4f3eA:undetectable | 1dedA-4f3eA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3e | SUPEROXIDE DISMUTASE (Trypanosomacruzi) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 196GLY A 180ASN A 102PRO A 182 | None | 1.21A | 1dedA-4h3eA:undetectable | 1dedA-4h3eA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iug | BETA-GALACTOSIDASE A (Aspergillusoryzae) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | TRP A 307GLY A 308ASN A 936PRO A 310 | NoneNAG A1149 (-3.4A)NoneMAN A1153 (-3.7A) | 1.20A | 1dedA-4iugA:9.8 | 1dedA-4iugA:22.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | TRP A 617LYS A 652GLY A 666ASN A 668 | None | 0.99A | 1dedA-4jclA:61.3 | 1dedA-4jclA:67.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | TRP A 617LYS A 652TRP A 663GLY A 665ASN A 668 | None | 0.64A | 1dedA-4jclA:61.3 | 1dedA-4jclA:67.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jcm | CYCLODEXTRINGLUCANOTRANSFERASE ([Bacillus]clarkii) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | TRP A 603LYS A 638GLY A 653ASN A 655 | GOL A 738 ( 3.9A)GOL A 738 (-3.6A)NoneGOL A 738 (-3.2A) | 1.01A | 1dedA-4jcmA:58.7 | 1dedA-4jcmA:54.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jcm | CYCLODEXTRINGLUCANOTRANSFERASE ([Bacillus]clarkii) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | TRP A 603LYS A 638TRP A 650ASN A 655 | GOL A 738 ( 3.9A)GOL A 738 (-3.6A)GOL A 738 ( 4.6A)GOL A 738 (-3.2A) | 0.32A | 1dedA-4jcmA:58.7 | 1dedA-4jcmA:54.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oht | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Streptococcuspyogenes) |
PF00171(Aldedh) | 4 | TRP A 418GLY A 260ASN A 132PRO A 364 | None | 1.19A | 1dedA-4ohtA:undetectable | 1dedA-4ohtA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pyh | PHOSPHOGLUCANPHOSPHATASE DSP4,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00782(DSPc)PF16561(AMPK1_CBM) | 4 | TRP A 278LYS A 307TRP A 314ASN A 332 | GLC A 405 ( 3.7A)GLC A 406 (-2.9A)GLC A 406 (-4.0A)GLC A 405 (-2.9A) | 0.41A | 1dedA-4pyhA:7.3 | 1dedA-4pyhA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkk | LAFORIN (Homo sapiens) |
PF00686(CBM_20)PF00782(DSPc) | 4 | TRP A 32LYS A 87TRP A 99GLY A 101 | GLC A 417 ( 3.7A)GLC A 414 (-2.7A)GLC A 414 (-3.9A)None | 0.48A | 1dedA-4rkkA:7.7 | 1dedA-4rkkA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzf | 1,3-BETA-GLUCANASE (Mycobacteriumtuberculosis) |
PF00722(Glyco_hydro_16) | 4 | TRP A 134TRP A 142GLY A 139PRO A 218 | None | 1.38A | 1dedA-4wzfA:undetectable | 1dedA-4wzfA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xdq | GLYCOSIDE HYDROLASEFAMILY PROTEIN (Mycolicibacteriumthermoresistibile) |
PF00722(Glyco_hydro_16) | 4 | TRP A 106TRP A 114GLY A 111PRO A 190 | None | 1.35A | 1dedA-4xdqA:undetectable | 1dedA-4xdqA:15.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xz6 | GLYCINEBETAINE/PROLINE ABCTRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Ruegeriapomeroyi) |
PF04069(OpuAC) | 4 | TRP A 204TRP A 231GLY A 233ASN A 221 | None | 1.23A | 1dedA-4xz6A:undetectable | 1dedA-4xz6A:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0g | 5'-AMP-ACTIVATEDPROTEIN KINASESUBUNIT BETA-2 (Rattusnorvegicus) |
PF16561(AMPK1_CBM) | 4 | TRP A 99LYS A 126TRP A 133ASN A 150 | None | 0.67A | 1dedA-4y0gA:4.6 | 1dedA-4y0gA:9.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yef | 5'-AMP-ACTIVATEDPROTEIN KINASESUBUNIT BETA-1 (Rattusnorvegicus) |
PF16561(AMPK1_CBM) | 4 | TRP A 100LYS A 126TRP A 133ASN A 150 | 4CQ A 201 (-3.8A)4CQ A 201 (-2.8A)4CQ A 201 (-4.0A)4CQ A 201 (-2.9A) | 0.34A | 1dedA-4yefA:6.8 | 1dedA-4yefA:8.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yet | SUPEROXIDE DISMUTASE (Babesia bovis) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | TRP A 160GLY A 143ASN A 66PRO A 145 | None | 1.23A | 1dedA-4yetA:undetectable | 1dedA-4yetA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxw | C-DOMAIN TYPE IIPEPTIDE SYNTHETASE (Streptomycesglobisporus) |
PF00668(Condensation) | 4 | LYS A 237GLY A 37ASN A 426PRO A 41 | None | 1.29A | 1dedA-4zxwA:undetectable | 1dedA-4zxwA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihr | PROBABLEBETA-GALACTOSIDASE A (Aspergillusniger) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | TRP A 307GLY A 308ASN A 938PRO A 310 | NoneMAN A1917 (-3.3A)NoneNone | 1.24A | 1dedA-5ihrA:11.0 | 1dedA-5ihrA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0y | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT I (Oryctolaguscuniculus) |
PF00400(WD40) | 4 | TRP T 56GLY T 53ASN T 74PRO T 32 | None | 1.48A | 1dedA-5k0yT:undetectable | 1dedA-5k0yT:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kq5 | 5'-AMP-ACTIVATEDPROTEIN KINASESUBUNIT BETA-1 (Rattusnorvegicus) |
PF04739(AMPKBI)PF16561(AMPK1_CBM) | 4 | TRP B 100LYS B 126TRP B 133ASN B 150 | None | 0.69A | 1dedA-5kq5B:6.7 | 1dedA-5kq5B:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ncl | SERINE/THREONINE-PROTEIN KINASE CBK1 (Saccharomycescerevisiae) |
no annotation | 4 | LYS A 477GLY A 573ASN A 480PRO A 575 | ANP A 801 (-2.7A)NoneANP A 801 (-3.8A)None | 1.42A | 1dedA-5nclA:undetectable | 1dedA-5nclA:8.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t79 | ALDO-KETO REDUCTASE,OXIDOREDUCTASE (Salmonellaenterica) |
PF00248(Aldo_ket_red) | 4 | TRP A 33GLY A 67ASN A 35PRO A 69 | NDP A 404 (-3.4A)NoneNDP A 404 ( 4.6A)None | 1.33A | 1dedA-5t79A:8.6 | 1dedA-5t79A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eq8 | PERIPLASMICALPHA-GALACTOSIDE-BINDING PROTEIN (Agrobacteriumtumefaciens) |
no annotation | 4 | LYS D 259GLY D 105ASN D 256PRO D 190 | None | 1.47A | 1dedA-6eq8D:undetectable | 1dedA-6eq8D:7.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhv | GLUCOAMYLASE (Penicilliumoxalicum) |
no annotation | 4 | TRP A 542LYS A 578GLY A 593ASN A 595 | PEG A 654 (-3.6A)NoneNonePEG A 654 ( 4.4A) | 1.04A | 1dedA-6fhvA:10.8 | 1dedA-6fhvA:7.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhv | GLUCOAMYLASE (Penicilliumoxalicum) |
no annotation | 4 | TRP A 542LYS A 578TRP A 590ASN A 595 | PEG A 654 (-3.6A)NonePEG A 654 ( 4.2A)PEG A 654 ( 4.4A) | 0.44A | 1dedA-6fhvA:10.8 | 1dedA-6fhvA:7.45 |