SIMILAR PATTERNS OF AMINO ACIDS FOR 1DB1_A_VDXA428_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aql | BILE-SALT ACTIVATEDLIPASE (Bos taurus) |
PF00135(COesterase) | 4 | LEU A 164ILE A 102TRP A 103TYR A 105 | None | 1.14A | 1db1A-1aqlA:undetectable | 1db1A-1aqlA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f5n | INTERFERON-INDUCEDGUANYLATE-BINDINGPROTEIN 1 (Homo sapiens) |
PF02263(GBP)PF02841(GBP_C) | 4 | LEU A 148ILE A 78TYR A 300VAL A 44 | None | 1.04A | 1db1A-1f5nA:0.7 | 1db1A-1f5nA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jfr | LIPASE (Streptomycesexfoliatus) |
PF03403(PAF-AH_p_II) | 4 | ILE A 231ARG A 124TYR A 237VAL A 84 | None | 1.01A | 1db1A-1jfrA:undetectable | 1db1A-1jfrA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jiu | DNABETA-GLUCOSYLTRANSFERASE (Escherichiavirus T4) |
PF09198(T4-Gluco-transf) | 4 | LEU A 324ILE A 255ARG A 269TRP A 271 | NoneNoneUDP A 353 (-3.9A)None | 1.06A | 1db1A-1jiuA:0.0 | 1db1A-1jiuA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n5x | XANTHINEDEHYDROGENASE (Bos taurus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 4 | ILE A1097ARG A1100TYR A1024VAL A1090 | None | 0.87A | 1db1A-1n5xA:0.0 | 1db1A-1n5xA:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1onl | GLYCINE CLEAVAGESYSTEM H PROTEIN (Thermusthermophilus) |
PF01597(GCV_H) | 4 | LEU A 111ILE A 76ARG A 48VAL A 25 | None | 0.96A | 1db1A-1onlA:0.0 | 1db1A-1onlA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p1m | HYPOTHETICAL PROTEINTM0936 (Thermotogamaritima) |
PF01979(Amidohydro_1) | 4 | LEU A 138ILE A 214TYR A 176VAL A 197 | None | 1.06A | 1db1A-1p1mA:0.0 | 1db1A-1p1mA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rmg | RHAMNOGALACTURONASEA (Aspergillusaculeatus) |
PF00295(Glyco_hydro_28) | 4 | LEU A 103ILE A 186TYR A 164VAL A 135 | NoneNoneMAN A 431 ( 4.2A)None | 1.10A | 1db1A-1rmgA:undetectable | 1db1A-1rmgA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1si1 | IRON BINDING PROTEINFBPA (Mannheimiahaemolytica) |
PF13343(SBP_bac_6) | 4 | ILE A 231ARG A 101TYR A 301VAL A 235 | None FE A 321 ( 4.2A)NoneNone | 1.00A | 1db1A-1si1A:0.0 | 1db1A-1si1A:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdq | AGGRECAN COREPROTEINTENASCIN-R (Rattusnorvegicus) |
PF00041(fn3)PF00059(Lectin_C) | 4 | LEU A 186ILE B 103ARG B 85TYR A 162 | None | 1.12A | 1db1A-1tdqA:undetectable | 1db1A-1tdqA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w5t | ORC2 (Aeropyrumpernix) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | LEU A 306ARG A 336TYR A 345VAL A 368 | None | 1.05A | 1db1A-1w5tA:undetectable | 1db1A-1w5tA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2acm | MUCIN-1 (Homo sapiens) |
PF01390(SEA)no annotation | 4 | LEU A1069ILE B1136TYR B1132VAL B1101 | None | 1.11A | 1db1A-2acmA:undetectable | 1db1A-2acmA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9w | MAST/STEM CELLGROWTH FACTORRECEPTOR (Homo sapiens) |
PF00047(ig) | 4 | ILE A 235ARG A 271TRP A 246VAL A 211 | None | 0.84A | 1db1A-2e9wA:undetectable | 1db1A-2e9wA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g2p | TRANSTHYRETIN-LIKEPROTEIN (Escherichiacoli) |
PF00576(Transthyretin) | 4 | LEU A 6ILE A 84TYR A 111VAL A 24 | NoneNoneSO4 A1102 (-4.2A)None | 1.09A | 1db1A-2g2pA:undetectable | 1db1A-2g2pA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gf0 | GTP-BINDING PROTEINDI-RAS1 (Homo sapiens) |
PF00071(Ras) | 4 | LEU A 160ILE A 104TRP A 142VAL A 10 | None | 1.03A | 1db1A-2gf0A:undetectable | 1db1A-2gf0A:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hn1 | MAGNESIUM AND COBALTTRANSPORTER (Archaeoglobusfulgidus) |
PF01544(CorA) | 4 | LEU A 113ILE A 152ARG A 153VAL A 138 | None | 1.11A | 1db1A-2hn1A:undetectable | 1db1A-2hn1A:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i71 | HYPOTHETICAL PROTEIN (Sulfolobussolfataricus) |
PF09455(Cas_DxTHG) | 4 | LEU A 176ILE A 81TYR A 15VAL A 5 | None | 1.02A | 1db1A-2i71A:undetectable | 1db1A-2i71A:19.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2o4j | VITAMIN D3 RECEPTOR (Rattusnorvegicus) |
PF00104(Hormone_recep) | 6 | LEU A 223ILE A 267ARG A 270TRP A 282TYR A 291VAL A 414 | NoneVD4 A 500 ( 4.7A)VD4 A 500 ( 4.0A)VD4 A 500 ( 3.7A)NoneNone | 0.18A | 1db1A-2o4jA:38.4 | 1db1A-2o4jA:90.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph7 | UNCHARACTERIZEDPROTEIN AF_2093 (Archaeoglobusfulgidus) |
no annotation | 4 | LEU A 196ILE A 208TYR A 214VAL A 171 | None | 1.13A | 1db1A-2ph7A:undetectable | 1db1A-2ph7A:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pie | E3 UBIQUITIN-PROTEINLIGASE RNF8 (Homo sapiens) |
PF00498(FHA) | 4 | LEU A 66ILE A 59ARG A 42VAL A 85 | None | 0.99A | 1db1A-2pieA:undetectable | 1db1A-2pieA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2tpt | THYMIDINEPHOSPHORYLASE (Escherichiacoli) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | LEU A 284ARG A 315TYR A 108VAL A 303 | None | 1.09A | 1db1A-2tptA:undetectable | 1db1A-2tptA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v5t | NEURAL CELL ADHESIONMOLECULE 2 (Homo sapiens) |
PF07679(I-set) | 4 | LEU A 250ILE A 258ARG A 269TYR A 279 | None | 1.09A | 1db1A-2v5tA:undetectable | 1db1A-2v5tA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x9p | PIMD PROTEIN (Streptomycesnatalensis) |
PF00067(p450) | 4 | LEU A 151ILE A 210ARG A 213VAL A 160 | None | 1.11A | 1db1A-2x9pA:1.8 | 1db1A-2x9pA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yrv | AT-RICH INTERACTIVEDOMAIN-CONTAININGPROTEIN 4A (Homo sapiens) |
PF08169(RBB1NT) | 4 | LEU A 86ILE A 67ARG A 64VAL A 70 | None | 1.10A | 1db1A-2yrvA:undetectable | 1db1A-2yrvA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a1n | NDP-SUGAR EPIMERASE (Thermoplasmavolcanium) |
PF01370(Epimerase) | 4 | LEU A 220ILE A 167TYR A 18VAL A 236 | NoneNAD A3001 ( 4.9A)NoneNone | 0.89A | 1db1A-3a1nA:undetectable | 1db1A-3a1nA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3apq | DNAJ HOMOLOGSUBFAMILY C MEMBER10 (Mus musculus) |
PF00085(Thioredoxin)PF00226(DnaJ) | 4 | LEU A 192ILE A 132TRP A 168TYR A 154 | None | 1.03A | 1db1A-3apqA:1.5 | 1db1A-3apqA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8v | PUTATIVEACETYLTRANSFERASE (Desulfovibrioalaskensis) |
no annotation | 4 | LEU A 7ILE A 454TYR A 457VAL A 74 | None | 1.05A | 1db1A-3c8vA:undetectable | 1db1A-3c8vA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1r | FRUCTOSE-1,6-BISPHOSPHATASE CLASS IIGLPX (Escherichiacoli) |
PF03320(FBPase_glpX) | 4 | LEU A 66ILE A 49ARG A 2VAL A 12 | None | 1.14A | 1db1A-3d1rA:undetectable | 1db1A-3d1rA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e60 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN ]SYNTHASE II (Bartonellahenselae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | LEU A 413ARG A 365TYR A 307VAL A 246 | None | 1.12A | 1db1A-3e60A:undetectable | 1db1A-3e60A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eya | PYRUVATEDEHYDROGENASE[CYTOCHROME] (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | LEU A 130ILE A 9TYR A 127VAL A 163 | None | 1.13A | 1db1A-3eyaA:undetectable | 1db1A-3eyaA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fo5 | THIOESTERASE,ADIPOSE ASSOCIATED,ISOFORM BFIT2 (Homo sapiens) |
PF01852(START) | 4 | LEU A 443ARG A 414TYR A 547VAL A 432 | None | 0.88A | 1db1A-3fo5A:undetectable | 1db1A-3fo5A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdn | R-OXYNITRILE LYASEISOENZYME 1 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 201ILE A 254ARG A 483VAL A 51 | None | 0.88A | 1db1A-3gdnA:undetectable | 1db1A-3gdnA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3grc | SENSOR PROTEIN,KINASE (Polaromonas sp.JS666) |
PF00072(Response_reg) | 4 | LEU A 567ILE A 624TYR A 592VAL A 627 | None | 1.10A | 1db1A-3grcA:undetectable | 1db1A-3grcA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5i | RESPONSEREGULATOR/SENSORYBOX PROTEIN/GGDEFDOMAIN PROTEIN (Carboxydothermushydrogenoformans) |
PF00072(Response_reg) | 4 | LEU A 120ILE A 19TYR A 26VAL A 80 | None | 1.06A | 1db1A-3h5iA:undetectable | 1db1A-3h5iA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jv9 | TRANSCRIPTIONALREGULATOR, LYSRFAMILY (Neisseriameningitidis) |
PF03466(LysR_substrate) | 4 | LEU A 205ILE A 232ARG A 233VAL A 191 | None | 1.06A | 1db1A-3jv9A:undetectable | 1db1A-3jv9A:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kom | TRANSKETOLASE (Francisellatularensis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | LEU A 47ILE A 13ARG A 14TYR A 295 | None | 1.12A | 1db1A-3komA:undetectable | 1db1A-3komA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ky9 | PROTO-ONCOGENE VAV (Homo sapiens) |
PF00130(C1_1)PF00169(PH)PF00621(RhoGEF)PF11971(CAMSAP_CH) | 4 | LEU A 145ILE A 75ARG A 76VAL A 108 | None | 1.10A | 1db1A-3ky9A:undetectable | 1db1A-3ky9A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzu | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)SYNTHASE II (Brucellamelitensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | LEU A 413ARG A 365TYR A 307VAL A 246 | None | 1.10A | 1db1A-3kzuA:undetectable | 1db1A-3kzuA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm4 | CATECHOL2,3-DIOXYGENASE (Rhodococcusjostii) |
PF00903(Glyoxalase) | 4 | LEU A 117ILE A 153TRP A 55VAL A 202 | None | 1.05A | 1db1A-3lm4A:undetectable | 1db1A-3lm4A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lsp | DEST (Pseudomonasaeruginosa) |
PF00440(TetR_N) | 4 | LEU A 169ILE A 121TYR A 115VAL A 67 | None | 1.11A | 1db1A-3lspA:undetectable | 1db1A-3lspA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mm5 | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT BETA (Archaeoglobusfulgidus) |
PF00037(Fer4)PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | LEU B 256ILE B 207ARG B 208VAL B 236 | SF4 B 586 ( 4.9A)NoneNoneNone | 1.09A | 1db1A-3mm5B:undetectable | 1db1A-3mm5B:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6x | PUTATIVEGLUTATHIONYLSPERMIDINE SYNTHASE (Methylobacillusflagellatus) |
PF14403(CP_ATPgrasp_2) | 4 | LEU A 163ILE A 110TYR A 105VAL A 326 | None | 1.10A | 1db1A-3n6xA:undetectable | 1db1A-3n6xA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o04 | BETA-KETO-ACYLCARRIER PROTEINSYNTHASE II (Listeriamonocytogenes) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | LEU A 406ARG A 358TYR A 299VAL A 238 | None | 1.07A | 1db1A-3o04A:undetectable | 1db1A-3o04A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6n | APL1 (Anophelesgambiae) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | LEU A 321ILE A 350TYR A 380VAL A 313 | None | 0.98A | 1db1A-3o6nA:undetectable | 1db1A-3o6nA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oja | ANOPHELESPLASMODIUM-RESPONSIVE LEUCINE-RICHREPEAT PROTEIN 1 (Anophelesgambiae) |
PF13855(LRR_8) | 4 | LEU B 321ILE B 350TYR B 380VAL B 313 | None | 0.94A | 1db1A-3ojaB:undetectable | 1db1A-3ojaB:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p5p | TAXADIENE SYNTHASE (Taxusbrevifolia) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | LEU A 311ILE A 236ARG A 266TYR A 140 | None | 1.08A | 1db1A-3p5pA:2.1 | 1db1A-3p5pA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qbd | 3-DEHYDROQUINATESYNTHASE (Mycobacteriumtuberculosis) |
PF01761(DHQ_synthase) | 4 | LEU A 217ILE A 297ARG A 293VAL A 187 | None | 0.97A | 1db1A-3qbdA:undetectable | 1db1A-3qbdA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r1x | 2-OXO-3-DEOXYGALACTONATE KINASE (Klebsiellapneumoniae) |
PF05035(DGOK) | 4 | LEU A 228ILE A 266ARG A 268TYR A 259 | None | 1.05A | 1db1A-3r1xA:undetectable | 1db1A-3r1xA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3red | HYDROXYNITRILE LYASE (Prunus mume) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 201ILE A 255ARG A 484VAL A 51 | None | 0.91A | 1db1A-3redA:undetectable | 1db1A-3redA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sr6 | XANTHINEDEHYDROGENASE/OXIDASE (Bos taurus) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | ILE C1097ARG C1100TYR C1024VAL C1090 | None | 0.91A | 1db1A-3sr6C:undetectable | 1db1A-3sr6C:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sut | BETA-HEXOSAMINIDASE (Paenibacillussp. TS12) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b) | 4 | LEU A 60ILE A 153TRP A 467VAL A 110 | None | 1.13A | 1db1A-3sutA:undetectable | 1db1A-3sutA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t43 | HIV EPITOPE-SCAFFOLD4E10_1XIZA_S0_006_C (syntheticconstruct) |
PF00359(PTS_EIIA_2) | 4 | LEU A 11ILE A 110TRP A 105VAL A 85 | None | 1.11A | 1db1A-3t43A:undetectable | 1db1A-3t43A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w8j | PROTEINDISULFIDE-ISOMERASEA6 (Homo sapiens) |
PF00085(Thioredoxin) | 4 | LEU A 89ILE A 28TRP A 65TYR A 51 | None | 1.12A | 1db1A-3w8jA:undetectable | 1db1A-3w8jA:17.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3wgp | VITAMIN D3 RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 227ILE A 271ARG A 274TRP A 286TYR A 295VAL A 418 | NoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.5A)NoneNone | 0.14A | 1db1A-3wgpA:42.0 | 1db1A-3wgpA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvs | PUTATIVEMONOOXYGENASE (Streptomycessp. SN-593) |
PF00067(p450) | 4 | LEU A 38ILE A 344TYR A 29VAL A 61 | None | 0.97A | 1db1A-3wvsA:undetectable | 1db1A-3wvsA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aby | DNA REPAIR PROTEINRECN (Deinococcusradiodurans) |
PF02463(SMC_N) | 4 | LEU A 155ILE A 399ARG A 400VAL A 445 | None | 1.08A | 1db1A-4abyA:undetectable | 1db1A-4abyA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecn | LEUCINE-RICH REPEATPROTEIN (Bacteroidesthetaiotaomicron) |
PF14660(DUF4458) | 4 | LEU A 201ILE A 287TYR A 252VAL A 246 | None | 1.02A | 1db1A-4ecnA:undetectable | 1db1A-4ecnA:14.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emi | TODA (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 4 | LEU A 21ILE A 33TYR A 67VAL A 104 | NoneFAD A 501 ( 4.6A)NoneNone | 0.98A | 1db1A-4emiA:undetectable | 1db1A-4emiA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxw | ADENOSINE DEAMINASE (Burkholderiaambifaria) |
PF00962(A_deaminase) | 4 | LEU A 87ILE A 62ARG A 59VAL A 41 | None | 1.04A | 1db1A-4gxwA:undetectable | 1db1A-4gxwA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7u | PYRANOSEDEHYDROGENASE (Leucoagaricusmeleagris) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 228ILE A 279ARG A 542VAL A 42 | None | 0.96A | 1db1A-4h7uA:undetectable | 1db1A-4h7uA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igo | OS05G0196500 PROTEIN (Oryza sativa) |
PF02373(JmjC)PF02375(JmjN) | 4 | LEU A 219TRP A 414TYR A 415VAL A 319 | None | 1.00A | 1db1A-4igoA:undetectable | 1db1A-4igoA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iqf | METHIONYL-TRNAFORMYLTRANSFERASE (Bacillusanthracis) |
PF00551(Formyl_trans_N)PF02911(Formyl_trans_C) | 4 | LEU A 238ILE A 225TYR A 235VAL A 272 | None | 1.09A | 1db1A-4iqfA:undetectable | 1db1A-4iqfA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jga | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Rickettsiarickettsii) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | LEU A 421ARG A 373TYR A 314VAL A 253 | None | 1.14A | 1db1A-4jgaA:undetectable | 1db1A-4jgaA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lqk | PROTEIN A46 (Vaccinia virus) |
no annotation | 4 | LEU C 184ARG C 159TYR C 98VAL C 150 | None | 1.10A | 1db1A-4lqkC:undetectable | 1db1A-4lqkC:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nle | ADENYLOSUCCINATELYASE (Mycolicibacteriumsmegmatis) |
PF00206(Lyase_1)PF10397(ADSL_C) | 4 | LEU A 349ILE A 338TYR A 468VAL A 294 | None | 1.03A | 1db1A-4nleA:undetectable | 1db1A-4nleA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2c | CRISPR-ASSOCIATEDHELICASE CAS3 (Thermobaculumterrenum) |
PF00271(Helicase_C) | 4 | LEU A 493ILE A 324ARG A 516VAL A 476 | None | 1.07A | 1db1A-4q2cA:undetectable | 1db1A-4q2cA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qrk | HYPOTHETICAL PROTEIN (Clostridiumsporogenes) |
PF09922(DUF2154)PF17115(Toast_rack_N) | 4 | LEU A 145ILE A 235TYR A 188VAL A 155 | None | 1.05A | 1db1A-4qrkA:undetectable | 1db1A-4qrkA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6h | SOLUTE BINDINGPROTEIN MSME (Bacillussubtilis) |
PF01547(SBP_bac_1) | 4 | LEU A 235ILE A 130ARG A 133VAL A 266 | None | 0.83A | 1db1A-4r6hA:undetectable | 1db1A-4r6hA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6y | PUTATIVE2-AMINOETHYLPHOSPHONATE-BINDINGPERIPLASMIC PROTEIN (Salmonellaenterica) |
PF13343(SBP_bac_6) | 4 | LEU A 245ILE A 327TYR A 154VAL A 319 | None | 1.06A | 1db1A-4r6yA:undetectable | 1db1A-4r6yA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwf | ADRENOMEDULLINMALTOSE TRANSPORTERSUBUNIT, RECEPTORACTIVITY-MODIFYINGPROTEIN 2,CALCITONINGENE-RELATED PEPTIDETYPE 1 RECEPTORFUSION PROTEIN (Escherichiacoli;Homo sapiens) |
PF00214(Calc_CGRP_IAPP)PF02793(HRM)PF04901(RAMP)PF13416(SBP_bac_8) | 4 | LEU A1109ILE A1120TYR B 52VAL A1065 | None | 0.96A | 1db1A-4rwfA:undetectable | 1db1A-4rwfA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tsh | SURFACE PROTEINADHESIN (Streptococcusmutans) |
PF16364(Antigen_C) | 4 | LEU B1031ILE B1016ARG B1197VAL B1138 | None | 1.14A | 1db1A-4tshB:undetectable | 1db1A-4tshB:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvs | TORSIN-1A-INTERACTING PROTEIN 1 (Homo sapiens) |
PF05609(LAP1C) | 4 | LEU A 536ILE A 409TYR A 493VAL A 568 | None | 1.11A | 1db1A-4tvsA:undetectable | 1db1A-4tvsA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udr | GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE (Methylovorussp. MP688) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 215ILE A 263ARG A 497VAL A 32 | None | 1.10A | 1db1A-4udrA:undetectable | 1db1A-4udrA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ur8 | KETO-DEOXY-D-GALACTARATE DEHYDRATASE (Agrobacteriumtumefaciens) |
PF00701(DHDPS) | 4 | LEU A 292ILE A 240ARG A 239VAL A 218 | None | 1.05A | 1db1A-4ur8A:undetectable | 1db1A-4ur8A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wnx | NETRIN-4 (Mus musculus) |
PF00053(Laminin_EGF)PF00055(Laminin_N) | 4 | LEU A 47ILE A 221ARG A 146VAL A 258 | None | 1.08A | 1db1A-4wnxA:undetectable | 1db1A-4wnxA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgo | ANOPHELESPLASMODIUM-RESPONSIVE LEUCINE-RICHREPEAT PROTEIN 1B (Anophelesgambiae) |
PF13855(LRR_8) | 4 | LEU A 162ILE A 191TYR A 221VAL A 154 | None | 1.01A | 1db1A-4xgoA:undetectable | 1db1A-4xgoA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zk3 | SERPIN B3 (Homo sapiens) |
PF00079(Serpin) | 4 | LEU A 107ILE A 168ARG A 144VAL A 134 | None | 1.00A | 1db1A-4zk3A:undetectable | 1db1A-4zk3A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzd | TRANSCRIPTIONALREGULATOR, PADR-LIKEFAMILY (Lactococcuslactis) |
PF03551(PadR) | 4 | LEU A 45ILE A 63TYR A 51VAL A 20 | None | 0.94A | 1db1A-4zzdA:undetectable | 1db1A-4zzdA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3i | ANTI-HAEMAGGLUTININHA1 FAB HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | LEU C 45ILE C 50ARG C 59VAL C 112 | None | 0.90A | 1db1A-5a3iC:undetectable | 1db1A-5a3iC:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dt5 | BETA-GLUCOSIDASE (Exiguobacteriumantarcticum) |
PF00232(Glyco_hydro_1) | 4 | LEU A 204ILE A 77TRP A 79VAL A 154 | None | 0.90A | 1db1A-5dt5A:undetectable | 1db1A-5dt5A:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e25 | BRANCHED-CHAINAMINOTRANSFERASE (Geoglobusacetivorans) |
PF01063(Aminotran_4) | 4 | LEU A 28ILE A 93ARG A 91VAL A 20 | NoneNoneAKG A 302 ( 4.1A)None | 0.94A | 1db1A-5e25A:undetectable | 1db1A-5e25A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb5 | HNL ISOENZYME 5 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 201ILE A 255ARG A 484VAL A 51 | None | 0.85A | 1db1A-5eb5A:undetectable | 1db1A-5eb5A:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f3y | UNCONVENTIONALMYOSIN-VIIB (Mus musculus) |
PF00784(MyTH4) | 4 | ILE A1093TRP A1110TYR A1141VAL A1076 | None | 1.05A | 1db1A-5f3yA:undetectable | 1db1A-5f3yA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | LEU B 109ILE B 143TYR B 153VAL B 60 | None | 1.13A | 1db1A-5fq6B:undetectable | 1db1A-5fq6B:13.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fr8 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ILE A 84ARG A 85TYR A 143VAL A 59 | None | 0.75A | 1db1A-5fr8A:undetectable | 1db1A-5fr8A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gaj | DE NOVO DESIGNEDPROTEIN OR258 (syntheticconstruct) |
no annotation | 4 | LEU A 23ILE A 83ARG A 107VAL A 55 | None | 1.03A | 1db1A-5gajA:undetectable | 1db1A-5gajA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8b | 8-AMINO-3,8-DIDEOXY-ALPHA-D-MANNO-OCTULOSONATE TRANSAMINASE (Shewanellaoneidensis) |
PF01041(DegT_DnrJ_EryC1) | 4 | LEU A 112ILE A 356TYR A 326VAL A 120 | None | 0.99A | 1db1A-5k8bA:undetectable | 1db1A-5k8bA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqz | PUTATIVEBRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE (Archaeoglobusfulgidus) |
no annotation | 4 | LEU A 26ILE A 91ARG A 89VAL A 18 | None | 1.09A | 1db1A-5mqzA:undetectable | 1db1A-5mqzA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ncc | FATTY ACIDPHOTODECARBOXYLASE (Chlorellavariabilis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 281ILE A 338ARG A 606VAL A 110 | None | 0.80A | 1db1A-5nccA:undetectable | 1db1A-5nccA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ny0 | L. REUTERIS SRRPBINDING REGION (Lactobacillusreuteri) |
no annotation | 4 | LEU A 274ILE A 364TYR A 306VAL A 349 | None | 1.03A | 1db1A-5ny0A:undetectable | 1db1A-5ny0A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sui | RIBOSOME BIOGENESISPROTEIN NSA1 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 301ILE A 372TYR A 343VAL A 338 | None | 1.01A | 1db1A-5suiA:undetectable | 1db1A-5suiA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tpr | 3-DEHYDROQUINATESYNTHASE (Trichormusvariabilis) |
PF01761(DHQ_synthase) | 4 | LEU A 80ILE A 33TYR A 45VAL A 59 | NoneNoneNoneNAD A 503 (-4.9A) | 1.06A | 1db1A-5tprA:undetectable | 1db1A-5tprA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tvo | S-ADENOSYLMETHIONINEDECARBOXYLASEPROENZYME (Trypanosomabrucei) |
PF01536(SAM_decarbox) | 4 | ILE A 98ARG B 34TYR A 274VAL B 82 | NoneNoneNonePYR A 401 (-3.7A) | 1.07A | 1db1A-5tvoA:undetectable | 1db1A-5tvoA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2p | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Treponemapallidum) |
PF01547(SBP_bac_1) | 4 | LEU A 55ARG A 331TYR A 341VAL A 44 | None | 1.13A | 1db1A-5u2pA:undetectable | 1db1A-5u2pA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v9p | LYSINE-SPECIFICDEMETHYLASE 5A (Homo sapiens) |
PF00628(PHD)PF01388(ARID)PF02373(JmjC)PF02375(JmjN)PF02928(zf-C5HC2)PF08429(PLU-1) | 4 | LEU A 80TRP A 503TYR A 504VAL A 407 | None90S A 904 (-4.7A)NoneNone | 1.11A | 1db1A-5v9pA:undetectable | 1db1A-5v9pA:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vvh | OCTOPINECATABOLISM/UPTAKEOPERON REGULATORYPROTEIN OCCR (Agrobacteriumtumefaciens) |
PF03466(LysR_substrate) | 4 | ILE A 143ARG A 266TRP A 284VAL A 122 | None | 0.78A | 1db1A-5vvhA:undetectable | 1db1A-5vvhA:25.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdh | KINESIN-LIKE PROTEINKIFC1 (Homo sapiens) |
PF00225(Kinesin) | 4 | LEU A 628ILE A 464TYR A 622VAL A 564 | None | 1.14A | 1db1A-5wdhA:undetectable | 1db1A-5wdhA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykn | PROBABLELYSINE-SPECIFICDEMETHYLASE JMJ14 (Arabidopsisthaliana) |
no annotation | 4 | LEU A 121TRP A 329TYR A 330VAL A 234 | None | 1.03A | 1db1A-5yknA:undetectable | 1db1A-5yknA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yv5 | ATPASE RIL (Pyrococcusfuriosus) |
no annotation | 4 | LEU A 256ARG A 244TYR A 275VAL A 194 | None | 0.90A | 1db1A-5yv5A:undetectable | 1db1A-5yv5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fob | VITAMIN D3 RECEPTORA (Danio rerio) |
no annotation | 6 | LEU A 255ILE A 299ARG A 302TRP A 314TYR A 323VAL A 444 | NoneDZW A 501 (-4.7A)DZW A 501 (-3.8A)DZW A 501 (-3.5A)DZW A 501 (-3.6A)None | 0.28A | 1db1A-6fobA:37.2 | 1db1A-6fobA:23.26 |