SIMILAR PATTERNS OF AMINO ACIDS FOR 1D4Y_A_TPVA501_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a21 | TISSUE FACTOR (Oryctolaguscuniculus) |
PF01108(Tissue_fac)PF09294(Interfer-bind) | 4 | LEU A 121ALA A 166VAL A 177ILE A 175 | None | 0.65A | 1d4yB-1a21A:undetectable | 1d4yB-1a21A:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bbu | PROTEIN (LYSYL-TRNASYNTHETASE) (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | LEU A 326ALA A 379GLY A 419ILE A 384 | None | 0.67A | 1d4yB-1bbuA:0.0 | 1d4yB-1bbuA:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cmx | PROTEIN (UBIQUITINYUH1-UBAL) (Saccharomycescerevisiae) |
PF01088(Peptidase_C12) | 4 | ARG A 208LEU A 39GLY A 232ILE A 36 | None | 0.53A | 1d4yB-1cmxA:undetectable | 1d4yB-1cmxA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2f | MALY PROTEIN (Escherichiacoli) |
PF00155(Aminotran_1_2) | 4 | LEU A 167ALA A 120VAL A 114ILE A 116 | None | 0.63A | 1d4yB-1d2fA:undetectable | 1d4yB-1d2fA:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dlm | CATECHOL1,2-DIOXYGENASE (Acinetobactersp. ADP1) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 4 | LEU A 290ALA A 151GLY A 119ILE A 140 | None | 0.68A | 1d4yB-1dlmA:0.0 | 1d4yB-1dlmA:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dys | ENDOGLUCANASE (Humicolainsolens) |
PF01341(Glyco_hydro_6) | 4 | LEU A 170ILE A 66VAL A 134ILE A 175 | None | 0.71A | 1d4yB-1dysA:undetectable | 1d4yB-1dysA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1t | LYSYL-TRNASYNTHETASE, HEATINDUCIBLE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | LEU A 326ALA A 379GLY A 419ILE A 384 | NoneNoneNoneGOL A 609 ( 3.9A) | 0.65A | 1d4yB-1e1tA:0.0 | 1d4yB-1e1tA:12.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ek6 | UDP-GALACTOSE4-EPIMERASE (Homo sapiens) |
PF16363(GDP_Man_Dehyd) | 4 | LEU A 68ALA A 89ILE A 164ILE A 67 | NoneNAI A 400 (-3.7A)NoneNAI A 400 (-3.8A) | 0.69A | 1d4yB-1ek6A:undetectable | 1d4yB-1ek6A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g5g | FUSION PROTEIN (Avianavulavirus 1) |
PF00523(Fusion_gly) | 4 | LEU A 386GLY A 41ILE A 42ILE A 391 | None | 0.64A | 1d4yB-1g5gA:undetectable | 1d4yB-1g5gA:11.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq7 | PROCLAVAMINATEAMIDINO HYDROLASE (Streptomycesclavuligerus) |
PF00491(Arginase) | 4 | ALA A 244ILE A 292VAL A 277ILE A 236 | None | 0.66A | 1d4yB-1gq7A:undetectable | 1d4yB-1gq7A:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gzj | EGI (Thermoascusaurantiacus) |
PF00150(Cellulase) | 4 | ALA A 173GLY A 236ILE A 237ILE A 222 | None | 0.71A | 1d4yB-1gzjA:undetectable | 1d4yB-1gzjA:14.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ARG A 8LEU A 23ALA A 28GLY A 49ILE A 50 | A79 A 800 (-3.4A)A79 A 800 ( 3.8A)A79 A 800 (-3.1A)A79 A 800 ( 3.7A)A79 A 800 (-3.8A) | 0.58A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | ARG A 8LEU A 23ALA A 28GLY A 49ILE A 50VAL A 82 | A79 A 800 (-3.6A)A79 A 800 ( 4.0A)A79 A 800 (-3.2A)A79 A 800 (-3.4A)A79 A 800 ( 4.0A)A79 A 800 (-4.5A) | 0.53A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ARG A 8LEU A 23ASP A 25ALA A 28GLY A 49 | A79 A 800 (-3.4A)A79 A 800 ( 3.8A)A79 A 800 (-2.7A)A79 A 800 (-3.1A)A79 A 800 ( 3.7A) | 0.48A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | ARG A 8LEU A 23ASP A 25ALA A 28GLY A 49VAL A 82 | A79 A 800 (-3.6A)A79 A 800 ( 4.0A)A79 A 800 (-2.8A)A79 A 800 (-3.2A)A79 A 800 (-3.4A)A79 A 800 (-4.5A) | 0.44A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ARG A 8LEU A 23ASP A 25ALA A 28ILE A 84 | A79 A 800 (-3.4A)A79 A 800 ( 3.8A)A79 A 800 (-2.7A)A79 A 800 (-3.1A)A79 A 800 (-3.8A) | 1.04A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ARG A 8LEU A 23ASP A 25ALA A 28ILE A 84 | A79 A 800 (-3.6A)A79 A 800 ( 4.0A)A79 A 800 (-2.8A)A79 A 800 (-3.2A)A79 A 800 (-3.6A) | 1.02A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | LEU A 23ALA A 28GLY A 49ILE A 50VAL A 82ILE A 84 | A79 A 800 ( 3.8A)A79 A 800 (-3.1A)A79 A 800 ( 3.7A)A79 A 800 (-3.8A)A79 A 800 (-4.5A)A79 A 800 (-3.6A) | 0.53A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | LEU A 23ALA A 28GLY A 49ILE A 50VAL A 82ILE A 84 | A79 A 800 ( 4.0A)A79 A 800 (-3.2A)A79 A 800 (-3.4A)A79 A 800 ( 4.0A)A79 A 800 (-4.5A)A79 A 800 (-3.8A) | 0.54A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | LEU A 23ASP A 25ALA A 28GLY A 49VAL A 82ILE A 84 | A79 A 800 ( 3.8A)A79 A 800 (-2.7A)A79 A 800 (-3.1A)A79 A 800 ( 3.7A)A79 A 800 (-4.5A)A79 A 800 (-3.6A) | 0.44A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | LEU A 23ASP A 25ALA A 28GLY A 49VAL A 82ILE A 84 | A79 A 800 ( 4.0A)A79 A 800 (-2.8A)A79 A 800 (-3.2A)A79 A 800 (-3.4A)A79 A 800 (-4.5A)A79 A 800 (-3.8A) | 0.46A | 1d4yB-1hvcA:14.1 | 1d4yB-1hvcA:47.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ith | HEMOGLOBIN (CYANOMET) (Urechis caupo) |
PF00042(Globin) | 5 | LEU A 79ALA A 128GLY A 112VAL A 76ILE A 10 | None | 1.16A | 1d4yB-1ithA:undetectable | 1d4yB-1ithA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jft | PURINE NUCLEOTIDESYNTHESIS REPRESSOR (Escherichiacoli) |
PF00356(LacI)PF13377(Peripla_BP_3) | 4 | ALA A 66GLY A 63ILE A 93ILE A 78 | None | 0.64A | 1d4yB-1jftA:undetectable | 1d4yB-1jftA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jwq | N-ACETYLMURAMOYL-L-ALANINE AMIDASE CWLV (Paenibacilluspolymyxa) |
PF01520(Amidase_3) | 4 | LEU A 141ILE A 40VAL A 77ILE A 79 | None | 0.69A | 1d4yB-1jwqA:undetectable | 1d4yB-1jwqA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ot5 | KEXIN (Saccharomycescerevisiae) |
PF00082(Peptidase_S8)PF01483(P_proprotein) | 4 | LEU A 452ALA A 401GLY A 166ILE A 453 | None | 0.66A | 1d4yB-1ot5A:undetectable | 1d4yB-1ot5A:11.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8y | GLYCINEN-METHYLTRANSFERASE (Mus musculus) |
PF13847(Methyltransf_31) | 4 | GLY A 68ILE A 72VAL A 60ILE A 134 | None | 0.70A | 1d4yB-1r8yA:undetectable | 1d4yB-1r8yA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rif | DNA HELICASE UVSW (Escherichiavirus T4) |
PF04851(ResIII) | 4 | ALA A 237GLY A 257ILE A 132ILE A 242 | NoneNone AU A 287 ( 4.7A)None | 0.70A | 1d4yB-1rifA:undetectable | 1d4yB-1rifA:14.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 5 | ARG A 8LEU A 23ASP A 25GLY A 49ILE A 84 | None | 0.63A | 1d4yB-1sivA:18.4 | 1d4yB-1sivA:51.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 5 | ARG A 8LEU A 23GLY A 49ILE A 50ILE A 84 | None | 0.76A | 1d4yB-1sivA:18.4 | 1d4yB-1sivA:51.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 5 | LEU A 23ASP A 25ALA A 28GLY A 49ILE A 84 | None | 0.55A | 1d4yB-1sivA:18.4 | 1d4yB-1sivA:51.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1usy | ATPPHOSPHORIBOSYLTRANSFERASE REGULATORYSUBUNIT (Thermotogamaritima) |
PF13393(tRNA-synt_His) | 4 | ALA C 251ILE C 238VAL C 109ILE C 113 | None | 0.63A | 1d4yB-1usyC:undetectable | 1d4yB-1usyC:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vd6 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Thermusthermophilus) |
PF03009(GDPD) | 4 | LEU A 32ALA A 16GLY A 213ILE A 212 | NoneNoneNoneGOL A 300 ( 4.9A) | 0.70A | 1d4yB-1vd6A:undetectable | 1d4yB-1vd6A:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w8a | SLIT PROTEIN (Drosophilamelanogaster) |
PF00560(LRR_1)PF01462(LRRNT)PF01463(LRRCT)PF13855(LRR_8) | 4 | GLY A 609ILE A 610VAL A 658ILE A 655 | None | 0.53A | 1d4yB-1w8aA:undetectable | 1d4yB-1w8aA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdt | ELONGATION FACTOR GHOMOLOG (Thermusthermophilus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03764(EFG_IV)PF14492(EFG_II) | 4 | ALA A 237GLY A 231VAL A 208ILE A 212 | None | 0.65A | 1d4yB-1wdtA:undetectable | 1d4yB-1wdtA:9.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfb | ALDOLASE C (Homo sapiens) |
PF00274(Glycolytic) | 5 | ARG A 60LEU A 63ALA A 332GLY A 29ILE A 30 | None | 1.48A | 1d4yB-1xfbA:undetectable | 1d4yB-1xfbA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ysr | SENSOR-TYPEHISTIDINE KINASEPRRB (Mycobacteriumtuberculosis) |
PF02518(HATPase_c) | 5 | LEU A 309ALA A 367GLY A 373VAL A 304ILE A 306 | NoneNoneTRS A1001 (-3.3A)NoneNone | 1.14A | 1d4yB-1ysrA:undetectable | 1d4yB-1ysrA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z8l | GLUTAMATECARBOXYPEPTIDASE II (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 4 | LEU A 362ALA A 588GLY A 582ILE A 416 | None | 0.66A | 1d4yB-1z8lA:undetectable | 1d4yB-1z8lA:8.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bih | NITRATE REDUCTASE[NADPH] (Ogataea angusta) |
PF00174(Oxidored_molyb)PF03404(Mo-co_dimer) | 4 | LEU A 256ALA A 180VAL A 107ILE A 109 | None | 0.63A | 1d4yB-2bihA:undetectable | 1d4yB-2bihA:13.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bii | NITRATE REDUCTASE[NADPH] (Ogataea angusta) |
PF00174(Oxidored_molyb)PF03404(Mo-co_dimer) | 4 | LEU A 256ALA A 180VAL A 107ILE A 109 | None | 0.57A | 1d4yB-2biiA:undetectable | 1d4yB-2biiA:14.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwa | ENDOGLUCANASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | LEU A 5GLY A 205VAL A 36ILE A 34 | None | 0.66A | 1d4yB-2bwaA:undetectable | 1d4yB-2bwaA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cbn | RIBONUCLEASE Z (Escherichiacoli) |
PF12706(Lactamase_B_2) | 4 | ALA A 297ILE A 4VAL A 228ILE A 267 | None | 0.70A | 1d4yB-2cbnA:undetectable | 1d4yB-2cbnA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1g | ACID PHOSPHATASE (Francisellatularensis) |
PF04185(Phosphoesterase) | 4 | ALA A 25GLY A 312ILE A 311VAL A 38 | None | 0.64A | 1d4yB-2d1gA:undetectable | 1d4yB-2d1gA:12.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dr3 | UPF0273 PROTEINPH0284 (Pyrococcushorikoshii) |
PF06745(ATPase) | 4 | ALA A 129GLY A 84VAL A 89ILE A 55 | None | 0.70A | 1d4yB-2dr3A:undetectable | 1d4yB-2dr3A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e8y | AMYX PROTEIN (Bacillussubtilis) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 5 | LEU A 36GLY A 88ILE A 87VAL A 75ILE A 18 | None | 1.11A | 1d4yB-2e8yA:undetectable | 1d4yB-2e8yA:8.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ep5 | 350AA LONGHYPOTHETICALASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Sulfurisphaeratokodaii) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | LEU A 265GLY A 326VAL A 287ILE A 285 | None | 0.66A | 1d4yB-2ep5A:undetectable | 1d4yB-2ep5A:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f3o | PYRUVATEFORMATE-LYASE 2 (Archaeoglobusfulgidus) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | ARG A 18LEU A 69GLY A 83ILE A 86ILE A 76 | None | 1.23A | 1d4yB-2f3oA:undetectable | 1d4yB-2f3oA:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f8l | HYPOTHETICAL PROTEINLMO1582 (Listeriamonocytogenes) |
PF02384(N6_Mtase) | 5 | LEU A 321ALA A 306GLY A 269ILE A 289ILE A 320 | None | 1.49A | 1d4yB-2f8lA:undetectable | 1d4yB-2f8lA:14.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fmb | EQUINE INFECTIOUSANEMIA VIRUSPROTEASE (Equineinfectiousanemia virus) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25ALA A 28GLY A 55VAL A 87ILE A 89 | LP1 A 201 (-3.5A)NoneLP1 A 201 (-2.3A)LP1 A 201 (-3.5A)LP1 A 201 (-3.4A)LP1 A 201 ( 4.9A)LP1 A 201 (-4.2A) | 0.53A | 1d4yB-2fmbA:15.2 | 1d4yB-2fmbA:33.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2frv | PERIPLASMICHYDROGENASE (Desulfovibriogigas) |
no annotation | 4 | GLY L 508ILE L 507VAL L 524ILE L 520 | None | 0.69A | 1d4yB-2frvL:undetectable | 1d4yB-2frvL:11.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fvm | DIHYDROPYRIMIDINASE (Lachanceakluyveri) |
PF01979(Amidohydro_1) | 5 | ALA A 277GLY A 346ILE A 343VAL A 264ILE A 265 | None | 1.18A | 1d4yB-2fvmA:undetectable | 1d4yB-2fvmA:12.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ioy | PERIPLASMICSUGAR-BINDINGPROTEIN (Caldanaerobactersubterraneus) |
PF13407(Peripla_BP_4) | 4 | ALA A 27GLY A 245VAL A 36ILE A 34 | None | 0.60A | 1d4yB-2ioyA:undetectable | 1d4yB-2ioyA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n0s | FERREDOXIN,CHLOROPLASTIC (Chlamydomonasreinhardtii) |
PF00111(Fer2) | 4 | LEU B 5ALA B 29VAL B 3ILE B 14 | None | 0.70A | 1d4yB-2n0sB:undetectable | 1d4yB-2n0sB:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n76 | DE NOVO DESIGNEDPROTEIN LFR1 (syntheticconstruct) |
no annotation | 5 | LEU A 55ALA A 18GLY A 51VAL A 8ILE A 10 | None | 1.48A | 1d4yB-2n76A:undetectable | 1d4yB-2n76A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oca | ATP-DEPENDENT DNAHELICASE UVSW (Escherichiavirus T4) |
PF00271(Helicase_C)PF04851(ResIII) | 4 | ALA A 237GLY A 257ILE A 132ILE A 242 | None | 0.70A | 1d4yB-2ocaA:undetectable | 1d4yB-2ocaA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oej | 2,3-DIKETO-5-METHYLTHIOPENTYL-1-PHOSPHATE ENOLASE (Geobacilluskaustophilus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | LEU A 298ALA A 294GLY A 126ILE A 130 | None | 0.69A | 1d4yB-2oejA:undetectable | 1d4yB-2oejA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0l | LIPOATE-PROTEINLIGASE A (Streptococcusagalactiae) |
PF03099(BPL_LplA_LipB) | 4 | LEU A 49ILE A 240VAL A 13ILE A 15 | None | 0.62A | 1d4yB-2p0lA:undetectable | 1d4yB-2p0lA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qxl | HEAT SHOCK PROTEINHOMOLOG SSE1 (Saccharomycescerevisiae) |
PF00012(HSP70) | 4 | LEU A 7ILE A 163VAL A 141ILE A 143 | None | 0.64A | 1d4yB-2qxlA:undetectable | 1d4yB-2qxlA:9.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25ALA A 28GLY A 49ILE A 50ILE A 84 | AB1 A 501 ( 4.7A)NoneAB1 A 501 (-2.4A)AB1 A 501 (-3.5A)AB1 A 501 (-3.5A)AB1 A 501 (-3.8A)AB1 A 501 ( 4.2A) | 0.49A | 1d4yB-2rkfA:20.5 | 1d4yB-2rkfA:84.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rsp | RSV PROTEASE (Rous sarcomavirus) |
PF00077(RVP) | 5 | ARG A 10LEU A 35ASP A 37ALA A 40ILE A 108 | None | 0.82A | 1d4yB-2rspA:12.9 | 1d4yB-2rspA:33.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 4 | ARG A 210ALA A 332GLY A 329ILE A 234 | OMT A2473 (-3.9A)NoneNoneNone | 0.68A | 1d4yB-2vdcA:undetectable | 1d4yB-2vdcA:6.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvt | GLUTAMATE RACEMASE (Enterococcusfaecalis) |
PF01177(Asp_Glu_race) | 4 | LEU A 89ILE A 33VAL A 93ILE A 91 | None | 0.59A | 1d4yB-2vvtA:undetectable | 1d4yB-2vvtA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0f | WSAF (Geobacillusstearothermophilus) |
no annotation | 4 | LEU A 351ALA A 335GLY A 318ILE A 358 | None | 0.68A | 1d4yB-2x0fA:undetectable | 1d4yB-2x0fA:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xa7 | AP-2 COMPLEX SUBUNITBETA (Homo sapiens) |
PF01602(Adaptin_N) | 4 | LEU B 396ALA B 410ILE B 451ILE B 399 | None | 0.71A | 1d4yB-2xa7B:undetectable | 1d4yB-2xa7B:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y23 | MYOMESIN (Homo sapiens) |
PF07679(I-set) | 5 | ASP A1401GLY A1409ILE A1410VAL A1428ILE A1389 | None | 0.90A | 1d4yB-2y23A:undetectable | 1d4yB-2y23A:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 4 | ALA A 344GLY A 247VAL A 372ILE A 400 | None | 0.58A | 1d4yB-2y3sA:undetectable | 1d4yB-2y3sA:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfq | NAD-SPECIFICGLUTAMATEDEHYDROGENASE (Peptoniphilusasaccharolyticus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | LEU A 317ALA A 213GLY A 236ILE A 231ILE A 208 | None | 1.12A | 1d4yB-2yfqA:undetectable | 1d4yB-2yfqA:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yln | PUTATIVE ABCTRANSPORTER,PERIPLASMIC BINDINGPROTEIN, AMINO ACID (Neisseriagonorrhoeae) |
PF00497(SBP_bac_3) | 5 | LEU A 188ALA A 196ILE A 154VAL A 218ILE A 191 | None | 1.34A | 1d4yB-2ylnA:undetectable | 1d4yB-2ylnA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxb | COENZYMEB12-DEPENDENT MUTASE (Aeropyrumpernix) |
PF02310(B12-binding) | 5 | ARG A 90LEU A 87GLY A 76ILE A 75ILE A 79 | None | 1.35A | 1d4yB-2yxbA:undetectable | 1d4yB-2yxbA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3b | ATP-DEPENDENTPROTEASE HSLV (Bacillussubtilis) |
PF00227(Proteasome) | 4 | LEU A 111ALA A 10GLY A 21ILE A 102 | None | 0.69A | 1d4yB-2z3bA:undetectable | 1d4yB-2z3bA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z61 | PROBABLE ASPARTATEAMINOTRANSFERASE 2 (Methanocaldococcusjannaschii) |
PF00155(Aminotran_1_2) | 4 | ALA A 321GLY A 335ILE A 336ILE A 17 | None | 0.68A | 1d4yB-2z61A:undetectable | 1d4yB-2z61A:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zj8 | PUTATIVE SKI2-TYPEHELICASE (Pyrococcusfuriosus) |
PF00270(DEAD)PF00271(Helicase_C)PF14520(HHH_5) | 5 | LEU A 681ALA A 661GLY A 655VAL A 692ILE A 687 | None | 1.02A | 1d4yB-2zj8A:undetectable | 1d4yB-2zj8A:9.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0u | RESPONSE REGULATOR (Thermotogamaritima) |
PF00072(Response_reg) | 4 | ALA A 74ILE A 77VAL A 63ILE A 67 | PG4 A 205 (-4.1A)NoneNoneNone | 0.46A | 1d4yB-3a0uA:undetectable | 1d4yB-3a0uA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7m | CELLULASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | LEU A 5GLY A 196VAL A 36ILE A 34 | None | 0.70A | 1d4yB-3b7mA:undetectable | 1d4yB-3b7mA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3btp | SINGLE-STRANDDNA-BINDING PROTEIN (Agrobacteriumfabrum) |
PF07229(VirE2) | 4 | LEU A 151ILE A 265VAL A 120ILE A 118 | None | 0.69A | 1d4yB-3btpA:undetectable | 1d4yB-3btpA:10.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c24 | PUTATIVEOXIDOREDUCTASE (Jannaschia sp.CCS1) |
PF03807(F420_oxidored)PF16896(PGDH_C) | 4 | ALA A 39GLY A 23ILE A 26ILE A 55 | None | 0.63A | 1d4yB-3c24A:undetectable | 1d4yB-3c24A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cg0 | RESPONSE REGULATORRECEIVER MODULATEDDIGUANYLATE CYCLASEWITH PAS/PAC SENSOR (Desulfovibrioalaskensis) |
PF00072(Response_reg) | 4 | LEU A 57ILE A 25VAL A 10ILE A 12 | None | 0.63A | 1d4yB-3cg0A:undetectable | 1d4yB-3cg0A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clj | PROTEIN NRD1 (Saccharomycescerevisiae) |
PF04818(CTD_bind) | 5 | LEU A 108GLY A 73ILE A 72VAL A 104ILE A 105 | None | 1.08A | 1d4yB-3cljA:undetectable | 1d4yB-3cljA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cps | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Cryptosporidiumparvum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | ALA A 271GLY A 185ILE A 186VAL A 280ILE A 276 | None | 1.29A | 1d4yB-3cpsA:undetectable | 1d4yB-3cpsA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3deg | GTP-BINDING PROTEINLEPA (Escherichiacoli) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF06421(LepA_C) | 5 | LEU C 20GLY C 97ILE C 180VAL C 101ILE C 9 | None | 1.06A | 1d4yB-3degC:undetectable | 1d4yB-3degC:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfy | MUCONATECYCLOISOMERASE (Thermotogamaritima) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 291ILE A 290VAL A 157ILE A 186 | None | 0.66A | 1d4yB-3dfyA:undetectable | 1d4yB-3dfyA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dhu | ALPHA-AMYLASE (Lactobacillusplantarum) |
PF00128(Alpha-amylase) | 4 | LEU A 358ILE A 298VAL A 366ILE A 368 | None | 0.68A | 1d4yB-3dhuA:undetectable | 1d4yB-3dhuA:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dr5 | PUTATIVEO-METHYLTRANSFERASE (Corynebacteriumglutamicum) |
PF13578(Methyltransf_24) | 4 | LEU A 45ALA A 60ILE A 63ILE A 74 | None | 0.69A | 1d4yB-3dr5A:undetectable | 1d4yB-3dr5A:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g8m | SERINEHYDROXYMETHYLTRANSFERASE (Escherichiacoli) |
PF00464(SHMT) | 4 | ALA A 333GLY A 338VAL A 364ILE A 362 | None | 0.53A | 1d4yB-3g8mA:undetectable | 1d4yB-3g8mA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gi8 | UNCHARACTERIZEDPROTEIN MJ0609 (Methanocaldococcusjannaschii) |
PF13520(AA_permease_2) | 4 | ALA C 296GLY C 323ILE C 326VAL C 133 | None | 0.59A | 1d4yB-3gi8C:undetectable | 1d4yB-3gi8C:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzj | POLYNEURIDINE-ALDEHYDE ESTERASE (Rauvolfiaserpentina) |
PF00561(Abhydrolase_1) | 4 | LEU A 258ALA A 209ILE A 104ILE A 261 | None | 0.70A | 1d4yB-3gzjA:undetectable | 1d4yB-3gzjA:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdy | UDP-GALACTOPYRANOSEMUTASE (Deinococcusradiodurans) |
PF03275(GLF)PF13450(NAD_binding_8) | 5 | LEU A 230ALA A 49ILE A 256VAL A 237ILE A 235 | None | 0.81A | 1d4yB-3hdyA:undetectable | 1d4yB-3hdyA:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmb | N-ACETYLMURAMOYL-L-ALANINE AMIDASE XLYA (Bacillussubtilis) |
PF01510(Amidase_2) | 4 | LEU A 47ALA A 13GLY A 18ILE A 9 | None | 0.67A | 1d4yB-3hmbA:undetectable | 1d4yB-3hmbA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htn | PUTATIVE DNA BINDINGPROTEIN (Bacteroidesthetaiotaomicron) |
PF03479(DUF296) | 4 | LEU A 117GLY A 89ILE A 152ILE A 114 | None | 0.67A | 1d4yB-3htnA:undetectable | 1d4yB-3htnA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ian | CHITINASE (Lactococcuslactis) |
PF00704(Glyco_hydro_18) | 4 | LEU A 121ASP A 158GLY A 282VAL A 79 | None | 0.71A | 1d4yB-3ianA:undetectable | 1d4yB-3ianA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kal | HOMOGLUTATHIONESYNTHETASE (Glycine max) |
PF03199(GSH_synthase)PF03917(GSH_synth_ATP) | 5 | LEU A 234ALA A 320GLY A 280VAL A 284ILE A 289 | None | 1.33A | 1d4yB-3kalA:undetectable | 1d4yB-3kalA:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kly | PUTATIVE FORMATETRANSPORTER 1 (Vibrio cholerae) |
PF01226(Form_Nir_trans) | 4 | GLY A 123ILE A 126VAL A 49ILE A 46 | None | 0.68A | 1d4yB-3klyA:undetectable | 1d4yB-3klyA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kux | PUTATIVEOXIDOREDUCTASE (Yersinia pestis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | ALA A 236GLY A 277ILE A 278ILE A 239 | None | 0.71A | 1d4yB-3kuxA:undetectable | 1d4yB-3kuxA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mve | UPF0255 PROTEINVV1_0328 (Vibriovulnificus) |
PF06500(DUF1100) | 5 | ALA A 360GLY A 270ILE A 269VAL A 356ILE A 358 | None | 1.17A | 1d4yB-3mveA:undetectable | 1d4yB-3mveA:11.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | LEU A 23ASP A 25ALA A 28GLY A 49ILE A 50VAL A 82ILE A 84 | None | 0.61A | 1d4yB-3mwsA:19.5 | 1d4yB-3mwsA:78.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0w | ABC BRANCHED CHAINAMINO ACID FAMILYTRANSPORTER,PERIPLASMIC LIGANDBINDING PROTEIN (Paraburkholderiaxenovorans) |
PF13458(Peripla_BP_6) | 5 | ARG A 86LEU A 112ALA A 120GLY A 30ILE A 109 | None | 1.14A | 1d4yB-3n0wA:undetectable | 1d4yB-3n0wA:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2o | BIOSYNTHETICARGININEDECARBOXYLASE (Vibriovulnificus) |
PF02784(Orn_Arg_deC_N) | 4 | LEU A 99GLY A 203VAL A 339ILE A 341 | None | 0.56A | 1d4yB-3n2oA:undetectable | 1d4yB-3n2oA:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ncy | ADIC (Salmonellaenterica) |
PF13520(AA_permease_2) | 4 | ALA A 235GLY A 230ILE A 229ILE A 23 | None | 0.70A | 1d4yB-3ncyA:undetectable | 1d4yB-3ncyA:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvs | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Vibrio cholerae) |
PF00275(EPSP_synthase) | 4 | ALA A 132GLY A 127ILE A 126ILE A 165 | None | 0.65A | 1d4yB-3nvsA:undetectable | 1d4yB-3nvsA:11.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8l | 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE (Oryctolaguscuniculus) |
PF00365(PFK) | 4 | LEU A 711ILE A 425VAL A 523ILE A 525 | None | 0.71A | 1d4yB-3o8lA:undetectable | 1d4yB-3o8lA:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ot6 | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Pseudomonassyringae groupgenomosp. 3) |
PF00378(ECH_1) | 4 | LEU A 143ALA A 107GLY A 60ILE A 26 | None | 0.67A | 1d4yB-3ot6A:undetectable | 1d4yB-3ot6A:17.57 |