SIMILAR PATTERNS OF AMINO ACIDS FOR 1CTR_A_TFPA153_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggz CALMODULIN-RELATED
PROTEIN NB-1

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A  27
LEU A  32
MET A  51
GLU A  54
VAL A  63
 None
None
None
None
CA  A 150 ( 4.9A)
 0.47A 1ctrA-1ggzA:
12.4		 1ctrA-1ggzA:
84.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gtu GLUTATHIONE
S-TRANSFERASE

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 LEU A  85
GLU A  88
GLU A  92
ALA A 148
VAL A 155
 None
 1.11A 1ctrA-1gtuA:
undetectable		 1ctrA-1gtuA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6g ALPHA-1 CATENIN

(Homo sapiens) 		PF01044
(Vinculin) 		5 LEU A 538
GLU A 592
GLU A 596
ALA A 597
MET A 606
 None
 1.23A 1ctrA-1h6gA:
undetectable		 1ctrA-1h6gA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq7 OVOTRANSFERRIN

(Gallus gallus) 		PF00405
(Transferrin) 		5 ILE A 665
LEU A 657
GLU A 588
ALA A 587
VAL A 664
 None
 1.32A 1ctrA-1iq7A:
undetectable		 1ctrA-1iq7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jcf ROD
SHAPE-DETERMINING
PROTEIN MREB

(Thermotoga
maritima) 		PF06723
(MreB_Mbl) 		5 ILE A   8
LEU A  80
GLU A 120
ALA A 123
VAL A  98
 None
 1.28A 1ctrA-1jcfA:
undetectable		 1ctrA-1jcfA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jcm INDOLE-3-GLYCEROL-PH
OSPHATE SYNTHASE

(Escherichia
coli) 		PF00218
(IGPS) 		5 ILE P 183
LEU P 201
GLU P 171
ALA P 173
VAL P 181
 None
 1.21A 1ctrA-1jcmP:
undetectable		 1ctrA-1jcmP:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgs DNA BINDING RESPONSE
REGULATOR D

(Thermotoga
maritima) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		5 ILE A  51
LEU A  80
GLU A  11
ALA A  15
VAL A   7
 None
 1.25A 1ctrA-1kgsA:
undetectable		 1ctrA-1kgsA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT

(Klebsiella
pneumoniae) 		PF02288
(Dehydratase_MU) 		5 ILE B  32
GLU B  64
GLU B  65
ALA B 140
VAL B  30
 None
 1.15A 1ctrA-1mmfB:
undetectable		 1ctrA-1mmfB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rp0 THIAZOLE
BIOSYNTHETIC ENZYME

(Arabidopsis
thaliana) 		PF01946
(Thi4) 		5 GLU A 101
ILE A  68
GLU A  57
ALA A  54
VAL A  44
 None
 0.88A 1ctrA-1rp0A:
undetectable		 1ctrA-1rp0A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t2j M12-VARIABLE HEAVY
DOMAIN

(Homo sapiens) 		PF07686
(V-set) 		5 GLU A  85
ILE A  69
LEU A  80
GLU A  46
ALA A  60
 None
 1.26A 1ctrA-1t2jA:
undetectable		 1ctrA-1t2jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tol PROTEIN (FUSION
PROTEIN CONSISTING
OF MINOR COAT
PROTEIN, GLYCINE
RICH LINKER, TOLA,
AND A HIS TAG)

(Escherichia
coli;
Escherichia
virus M13) 		PF05357
(Phage_Coat_A)
PF06519
(TolA) 		5 GLU A  14
ILE A 159
LEU A 209
GLU A 141
ALA A 139
 None
 1.27A 1ctrA-1tolA:
undetectable		 1ctrA-1tolA:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		5 ILE A  36
LEU A  41
MET A  60
GLU A  63
VAL A  72
 None
None
TFP  A 202 ( 4.0A)
None
None
 0.62A 1ctrA-1wrkA:
10.4		 1ctrA-1wrkA:
60.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wx0 TRANSALDOLASE

(Thermus
thermophilus) 		PF00923
(TAL_FSA) 		5 ILE A 174
LEU A 139
ALA A 184
VAL A 180
MET A   1
 None
 1.32A 1ctrA-1wx0A:
undetectable		 1ctrA-1wx0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		5 GLU A 211
ILE A 180
LEU A 233
GLU A 218
ALA A 219
 None
 1.18A 1ctrA-1xrsA:
undetectable		 1ctrA-1xrsA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7p HYPOTHETICAL PROTEIN
AF1403

(Archaeoglobus
fulgidus) 		PF01842
(ACT) 		5 GLU A 116
ILE A  90
GLU A 145
ALA A 199
VAL A 148
 None
 1.16A 1ctrA-1y7pA:
undetectable		 1ctrA-1y7pA:
24.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE B 100
LEU B 105
MET B 124
ALA B 128
VAL B 136
MET B 144
 None
None
None
None
CA  B 800 ( 4.9A)
None
 0.64A 1ctrA-1zotB:
12.5		 1ctrA-1zotB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE B 100
LEU B 105
MET B 124
GLU B 127
ALA B 128
 None
 1.09A 1ctrA-1zotB:
12.5		 1ctrA-1zotB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bl0 MYOSIN REGULATORY
LIGHT CHAIN

(Physarum
polycephalum) 		PF13833
(EF-hand_8) 		5 ILE C  35
LEU C  40
MET C  59
ALA C  63
MET C  79
 None
 1.30A 1ctrA-2bl0C:
10.3		 1ctrA-2bl0C:
44.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bl0 MYOSIN REGULATORY
LIGHT CHAIN

(Physarum
polycephalum) 		PF13833
(EF-hand_8) 		5 ILE C  35
LEU C  40
MET C  59
GLU C  62
ALA C  63
 None
 1.26A 1ctrA-2bl0C:
10.3		 1ctrA-2bl0C:
44.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E

(Pyrococcus
horikoshii) 		PF01991
(vATP-synt_E) 		5 GLU A 104
ILE A 150
GLU A 140
GLU A 144
VAL A 148
 None
 1.14A 1ctrA-2dm9A:
undetectable		 1ctrA-2dm9A:
26.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 ILE A 100
GLU A 123
GLU A 127
ALA A 128
VAL A 136
 None
None
None
None
CA  A1004 ( 4.9A)
 1.18A 1ctrA-2f2pA:
12.0		 1ctrA-2f2pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 ILE A 100
GLU A 127
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A1004 ( 4.9A)
None
 1.09A 1ctrA-2f2pA:
12.0		 1ctrA-2f2pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A1004 ( 4.9A)
None
 0.76A 1ctrA-2f2pA:
12.0		 1ctrA-2f2pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
GLU A 123
VAL A 136
MET A 144
 None
None
None
CA  A1004 ( 4.9A)
None
 1.20A 1ctrA-2f2pA:
12.0		 1ctrA-2f2pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A 121
LEU A 126
MET A 145
ALA A 149
VAL A 157
 None
 0.63A 1ctrA-2ggmA:
12.8		 1ctrA-2ggmA:
45.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 LEU A 126
MET A 145
GLU A 148
ALA A 149
VAL A 157
 None
 0.91A 1ctrA-2ggmA:
12.8		 1ctrA-2ggmA:
45.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h09 TRANSCRIPTIONAL
REGULATOR MNTR

(Escherichia
coli) 		PF01325
(Fe_dep_repress)
PF02742
(Fe_dep_repr_C) 		5 ILE A  84
LEU A  94
ALA A  55
VAL A  92
MET A  60
 None
 1.17A 1ctrA-2h09A:
undetectable		 1ctrA-2h09A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i99 MU-CRYSTALLIN
HOMOLOG

(Homo sapiens) 		PF02423
(OCD_Mu_crystall) 		5 ILE A 223
GLU A 239
GLU A 243
ALA A 244
VAL A 289
 None
 1.21A 1ctrA-2i99A:
undetectable		 1ctrA-2i99A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		5 ILE A  27
LEU A 108
GLU A 396
ALA A 390
VAL A  26
 None
 1.31A 1ctrA-2iyfA:
undetectable		 1ctrA-2iyfA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjz IONIZED
CALCIUM-BINDING
ADAPTER MOLECULE 2

(Homo sapiens) 		no annotation 5 ILE B  67
LEU B  72
MET B  91
GLU B  94
MET B 111
 None
 0.70A 1ctrA-2jjzB:
7.8		 1ctrA-2jjzB:
22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k2i CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A 121
LEU A 126
MET A 145
ALA A 149
VAL A 157
 None
 0.89A 1ctrA-2k2iA:
10.1		 1ctrA-2k2iA:
35.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k2i CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 LEU A 126
MET A 145
GLU A 148
ALA A 149
VAL A 157
 None
 1.27A 1ctrA-2k2iA:
10.1		 1ctrA-2k2iA:
35.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 ILE A 100
GLU A 127
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 1.27A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.84A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
MET A 124
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.89A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 ILE A 100
MET A 124
GLU A 127
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 1.30A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lmv CALMODULIN-RELATED
PROTEIN 97A

(Drosophila
melanogaster) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
MET A 124
GLU A 127
ALA A 128
 None
 0.88A 1ctrA-2lmvA:
10.1		 1ctrA-2lmvA:
66.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A 100
GLU A 127
ALA A 128
VAL A 136
MET A 144
 None
 1.28A 1ctrA-2n6aA:
12.9		 1ctrA-2n6aA:
83.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
MET A 124
ALA A 128
MET A 144
 None
 1.28A 1ctrA-2n6aA:
12.9		 1ctrA-2n6aA:
83.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A 100
MET A 124
ALA A 128
VAL A 136
MET A 144
 None
 1.19A 1ctrA-2n6aA:
12.9		 1ctrA-2n6aA:
83.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n7l TROPONIN C/TROPONIN
I CHIMERA

(Homo sapiens) 		PF13833
(EF-hand_8) 		5 ILE C  36
LEU C  41
GLU C  63
VAL C  72
MET C  80
 4J4  C  84 ( 4.3A)
4J4  C  84 ( 4.1A)
None
CA  C 201 ( 4.6A)
4J4  C  84 ( 4.1A)
 1.18A 1ctrA-2n7lC:
8.0		 1ctrA-2n7lC:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n7l TROPONIN C/TROPONIN
I CHIMERA

(Homo sapiens) 		PF13833
(EF-hand_8) 		5 ILE C  36
MET C  60
GLU C  63
VAL C  72
MET C  80
 4J4  C  84 ( 4.3A)
None
None
CA  C 201 ( 4.6A)
4J4  C  84 ( 4.1A)
 1.30A 1ctrA-2n7lC:
8.0		 1ctrA-2n7lC:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2obh CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A 121
LEU A 126
MET A 145
ALA A 149
VAL A 157
 None
None
None
None
CA  A1001 ( 4.9A)
 0.61A 1ctrA-2obhA:
12.7		 1ctrA-2obhA:
52.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2obh CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 LEU A 126
MET A 145
GLU A 148
ALA A 149
VAL A 157
 None
None
None
None
CA  A1001 ( 4.9A)
 0.99A 1ctrA-2obhA:
12.7		 1ctrA-2obhA:
52.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qae DIHYDROLIPOYL
DEHYDROGENASE

(Trypanosoma
cruzi) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 ILE A 415
LEU A 423
GLU A 452
ALA A 453
VAL A 399
 None
 1.20A 1ctrA-2qaeA:
undetectable		 1ctrA-2qaeA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2raa PYRUVATE SYNTHASE
SUBUNIT PORC

(Thermotoga
maritima) 		PF01558
(POR) 		5 LEU A 142
MET A  26
GLU A  29
ALA A  30
VAL A 152
 None
 1.11A 1ctrA-2raaA:
undetectable		 1ctrA-2raaA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rb9 HYPE PROTEIN

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		5 ILE A 127
LEU A  32
MET A  24
GLU A  25
ALA A  26
 None
 1.15A 1ctrA-2rb9A:
undetectable		 1ctrA-2rb9A:
19.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rob CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
GLU A 127
ALA A 128
VAL A 136
 None
 1.05A 1ctrA-2robA:
10.5		 1ctrA-2robA:
59.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uuu ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE

(Dictyostelium
discoideum) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		5 ILE A 216
LEU A 244
MET A 312
ALA A 210
VAL A 200
 None
 1.21A 1ctrA-2uuuA:
undetectable		 1ctrA-2uuuA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8u SERINE
PALMITOYLTRANSFERASE

(Sphingomonas
wittichii) 		PF00155
(Aminotran_1_2) 		5 GLU A 162
ILE A 208
LEU A 181
GLU A 196
ALA A 199
 None
 1.21A 1ctrA-2x8uA:
undetectable		 1ctrA-2x8uA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5x AMINE OXIDASE
[FLAVIN-CONTAINING]
A

(Homo sapiens) 		PF01593
(Amino_oxidase) 		5 GLU A  83
LEU A 234
GLU A  34
ALA A  28
VAL A  18
 None
 1.22A 1ctrA-2z5xA:
undetectable		 1ctrA-2z5xA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3a BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01301
(Glyco_hydro_35) 		5 ILE A 174
LEU A 166
GLU A 107
ALA A 105
VAL A 112
 None
 1.11A 1ctrA-3d3aA:
undetectable		 1ctrA-3d3aA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dcx PROTEIN OF UNKNOWN
FUNCTION (DUF1696)
WITH
PLECKSTRIN-HOMOLOGY
DOMAINS

(Shewanella
loihica) 		PF08000
(bPH_1) 		5 ILE A 115
GLU A  78
GLU A  80
ALA A  89
VAL A 112
 MPD  A   5 ( 4.9A)
None
None
None
None
 1.12A 1ctrA-3dcxA:
undetectable		 1ctrA-3dcxA:
23.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A 403
LEU A 408
GLU A 426
ALA A 431
VAL A 439
 None
 1.30A 1ctrA-3evrA:
17.4		 1ctrA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A 403
LEU A 408
MET A 427
ALA A 431
VAL A 439
 None
 0.54A 1ctrA-3evrA:
17.4		 1ctrA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 LEU A 408
MET A 427
ALA A 431
VAL A 439
MET A 447
 None
 1.18A 1ctrA-3evrA:
17.4		 1ctrA-3evrA:
38.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdj PROBABLE ORNITHINE
CYCLODEAMINASE

(Bordetella
pertussis) 		PF02423
(OCD_Mu_crystall) 		5 ILE A   9
LEU A  97
GLU A 289
ALA A  18
VAL A  13
 None
 1.28A 1ctrA-3hdjA:
undetectable		 1ctrA-3hdjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxk SUGAR HYDROLASE

(Lactococcus
lactis) 		PF00326
(Peptidase_S9) 		5 ILE A  46
LEU A 124
GLU A  61
ALA A  66
VAL A  76
 None
 1.15A 1ctrA-3hxkA:
undetectable		 1ctrA-3hxkA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Bacillus
cytotoxicus) 		PF13377
(Peripla_BP_3) 		5 ILE A  74
LEU A  11
GLU A 263
ALA A 257
VAL A  96
 None
 1.06A 1ctrA-3k4hA:
undetectable		 1ctrA-3k4hA:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 ILE A 117
LEU A 122
MET A 141
GLU A 144
ALA A 145
VAL A 153
 None
 0.89A 1ctrA-3kf9A:
18.5		 1ctrA-3kf9A:
56.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 ILE A 117
LEU A 122
MET A 141
GLU A 144
MET A 162
 None
 1.08A 1ctrA-3kf9A:
18.5		 1ctrA-3kf9A:
56.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l19 CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF13499
(EF-hand_7) 		5 ILE A 466
LEU A 471
MET A 488
VAL A 500
MET A 508
 None
 0.70A 1ctrA-3l19A:
9.1		 1ctrA-3l19A:
28.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lij CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		5 ILE A 466
LEU A 471
MET A 488
VAL A 500
MET A 508
 None
 0.44A 1ctrA-3lijA:
8.6		 1ctrA-3lijA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnn DNA BINDING RESPONSE
REGULATOR D

(Thermotoga
maritima) 		PF00072
(Response_reg) 		5 ILE A  51
LEU A  80
GLU A  11
ALA A  15
VAL A   7
 None
 1.16A 1ctrA-3nnnA:
undetectable		 1ctrA-3nnnA:
23.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		5 ILE A  45
LEU A  50
MET A  69
GLU A  72
MET A  89
 None
 0.80A 1ctrA-3qrxA:
13.1		 1ctrA-3qrxA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s47 MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Clostridium
beijerinckii) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 GLU A 336
GLU A 259
GLU A 233
ALA A 256
VAL A 276
 None
MG  A 402 (-2.7A)
MG  A 402 (-2.8A)
None
None
 1.32A 1ctrA-3s47A:
undetectable		 1ctrA-3s47A:
15.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A 321
LEU A 326
MET A 345
GLU A 348
MET A 365
 None
 0.77A 1ctrA-3u0kA:
17.3		 1ctrA-3u0kA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A 394
LEU A 399
GLU A 421
ALA A 422
VAL A 430
 None
 1.20A 1ctrA-3u0kA:
17.3		 1ctrA-3u0kA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A 394
LEU A 399
MET A 418
ALA A 422
VAL A 430
 None
 0.65A 1ctrA-3u0kA:
17.3		 1ctrA-3u0kA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uiw GLUTAREDOXIN 2

(Danio rerio) 		PF00462
(Glutaredoxin) 		5 ILE A  86
LEU A 106
GLU A  49
ALA A  52
VAL A  29
 None
 1.22A 1ctrA-3uiwA:
undetectable		 1ctrA-3uiwA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE

(Caenorhabditis
elegans) 		PF00806
(PUF) 		5 ILE A 414
LEU A 417
GLU A 361
GLU A 358
ALA A 354
 None
 1.24A 1ctrA-3v71A:
undetectable		 1ctrA-3v71A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		5 ILE A 257
LEU A 513
GLU A 246
ALA A 180
VAL A 253
 None
 1.17A 1ctrA-4av6A:
undetectable		 1ctrA-4av6A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csu GTPASE OBGE/CGTA

(Escherichia
coli) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		5 GLU 9 295
ILE 9 263
LEU 9 280
GLU 9 302
ALA 9 303
 None
 1.30A 1ctrA-4csu9:
undetectable		 1ctrA-4csu9:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e9m NUCLEOTIDE-BINDING
OLIGOMERIZATION
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00619
(CARD) 		5 ILE A  71
LEU A  74
GLU A  53
GLU A  56
VAL A  41
 None
 1.30A 1ctrA-4e9mA:
undetectable		 1ctrA-4e9mA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eoz SPECKLE-TYPE POZ
PROTEIN

(Homo sapiens) 		PF00651
(BTB) 		5 GLU A 283
ILE A 243
ALA A 276
VAL A 246
MET A 254
 None
 1.16A 1ctrA-4eozA:
undetectable		 1ctrA-4eozA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdf MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C 2

(Mycobacterium
tuberculosis) 		PF01967
(MoaC) 		5 ILE A 151
MET A 122
GLU A 123
ALA A 124
VAL A 128
 None
 1.22A 1ctrA-4fdfA:
undetectable		 1ctrA-4fdfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfq RIBOSOME-RECYCLING
FACTOR

(Bacillus
anthracis) 		PF01765
(RRF) 		5 ILE A 174
LEU A  24
GLU A 123
ALA A 124
VAL A 171
 None
 1.06A 1ctrA-4gfqA:
undetectable		 1ctrA-4gfqA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gis ENOLASE

(Vibrio harveyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 GLU A 334
GLU A 257
GLU A 231
ALA A 254
VAL A 274
 None
MG  A 405 ( 2.4A)
MG  A 405 (-2.7A)
None
None
 1.30A 1ctrA-4gisA:
undetectable		 1ctrA-4gisA:
15.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE D 100
GLU D 123
GLU D 127
ALA D 128
VAL D 136
MET D 144
 ILE  D 100 ( 0.7A)
GLU  D 123 ( 0.6A)
GLU  D 127 ( 0.6A)
ALA  D 128 ( 0.0A)
VAL  D 136 ( 0.6A)
MET  D 144 ( 0.0A)
 1.27A 1ctrA-4gowD:
17.2		 1ctrA-4gowD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE D 100
LEU D 105
GLU D 127
ALA D 128
VAL D 136
MET D 144
 ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
GLU  D 127 ( 0.6A)
ALA  D 128 ( 0.0A)
VAL  D 136 ( 0.6A)
MET  D 144 ( 0.0A)
 1.00A 1ctrA-4gowD:
17.2		 1ctrA-4gowD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE D 100
LEU D 105
MET D 124
GLU D 127
ALA D 128
VAL D 136
 ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
MET  D 124 ( 0.0A)
GLU  D 127 ( 0.6A)
ALA  D 128 ( 0.0A)
VAL  D 136 ( 0.6A)
 0.71A 1ctrA-4gowD:
17.2		 1ctrA-4gowD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A 403
LEU A 408
MET A 427
ALA A 431
VAL A 439
 None
 0.65A 1ctrA-4i2yA:
17.1		 1ctrA-4i2yA:
65.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 LEU A 408
MET A 427
ALA A 431
VAL A 439
MET A 447
 None
 1.24A 1ctrA-4i2yA:
17.1		 1ctrA-4i2yA:
65.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j8z SPECKLE-TYPE POZ
PROTEIN

(Homo sapiens) 		PF00651
(BTB) 		5 GLU A 283
ILE A 243
ALA A 276
VAL A 246
MET A 254
 None
 1.14A 1ctrA-4j8zA:
undetectable		 1ctrA-4j8zA:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4jwq CALCIUM-DEPENDENT
PROTEIN KINASE

(Plasmodium
berghei) 		PF13499
(EF-hand_7) 		5 ILE A 145
LEU A 150
MET A 174
GLU A 177
MET A 194
 None
 0.68A 1ctrA-4jwqA:
11.3		 1ctrA-4jwqA:
30.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5p UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF09994
(DUF2235) 		5 GLU A 747
ILE A 601
LEU A 698
ALA A 750
VAL A 714
 None
 1.27A 1ctrA-4o5pA:
undetectable		 1ctrA-4o5pA:
10.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q57 CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 ILE A  27
LEU A  32
MET A  51
GLU A  54
MET A  71
 None
 0.91A 1ctrA-4q57A:
13.1		 1ctrA-4q57A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4g PUTATIVE LIPOPROTEIN
YCDA

(Bacillus
subtilis) 		PF11611
(DUF4352)
PF17118
(DUF5105) 		5 ILE A 250
LEU A 186
GLU A 349
ALA A 350
VAL A 268
 None
 1.30A 1ctrA-4r4gA:
undetectable		 1ctrA-4r4gA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4thi PROTEIN (THIAMINASE
I)

(Bacillus
subtilis) 		PF01547
(SBP_bac_1) 		5 ILE A 197
MET A 168
GLU A 171
ALA A 172
VAL A 196
 None
 1.27A 1ctrA-4thiA:
undetectable		 1ctrA-4thiA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y2w ALANINE RACEMASE 1

(Caldanaerobacter
subterraneus) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		5 ILE A 130
LEU A 162
GLU A 116
ALA A 112
VAL A 106
 None
 0.94A 1ctrA-4y2wA:
undetectable		 1ctrA-4y2wA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2k IG LAMBDA-1 CHAIN V
REGION S43

(Mus musculus) 		PF07686
(V-set) 		5 GLU H  85
ILE H  69
LEU H  80
GLU H  46
ALA H  60
 None
 1.30A 1ctrA-5a2kH:
undetectable		 1ctrA-5a2kH:
15.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d43 CENTRIN-1

(Mus musculus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 ILE A 121
LEU A 126
GLU A 148
ALA A 149
VAL A 157
 None
None
None
None
CA  A1204 ( 4.9A)
 1.29A 1ctrA-5d43A:
12.4		 1ctrA-5d43A:
46.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d43 CENTRIN-1

(Mus musculus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 ILE A 121
LEU A 126
MET A 145
ALA A 149
VAL A 157
 None
None
None
None
CA  A1204 ( 4.9A)
 0.67A 1ctrA-5d43A:
12.4		 1ctrA-5d43A:
46.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fus PUTATIVE ENOYL COA
HYDRATASE

(Burkholderia
cenocepacia) 		PF00378
(ECH_1) 		5 GLU A 158
ILE A 203
LEU A 202
ALA A 140
VAL A 146
 None
 1.11A 1ctrA-5fusA:
undetectable		 1ctrA-5fusA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjq AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Streptomyces
sp. ML694-90F3) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		5 ILE A 501
LEU A 484
GLU A 446
ALA A 453
VAL A 469
 None
 1.27A 1ctrA-5jjqA:
undetectable		 1ctrA-5jjqA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Acinetobacter
baumannii) 		PF00275
(EPSP_synthase) 		5 ILE A 206
LEU A 199
MET A 172
ALA A 174
VAL A 216
 None
 1.26A 1ctrA-5u4hA:
undetectable		 1ctrA-5u4hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 4

(Homo sapiens) 		PF00004
(AAA)
PF09079
(Cdc6_C)
PF13191
(AAA_16)
PF14629
(ORC4_C) 		5 GLU C  59
ILE A 705
GLU A 731
ALA A 729
VAL A 746
 None
 1.30A 1ctrA-5uj7C:
undetectable		 1ctrA-5uj7C:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 5 ILE A 365
LEU A 370
MET A 389
ALA A 393
VAL A 401
 None
 0.89A 1ctrA-5ukgA:
12.0		 1ctrA-5ukgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 5 ILE A 365
LEU A 370
MET A 389
GLU A 388
VAL A 401
 None
 1.21A 1ctrA-5ukgA:
12.0		 1ctrA-5ukgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eon BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 5 ILE A 174
LEU A 166
GLU A 107
ALA A 105
VAL A 112
 None
 1.09A 1ctrA-6eonA:
undetectable		 1ctrA-6eonA:
11.21