SIMILAR PATTERNS OF AMINO ACIDS FOR 1CLA_A_CLMA221_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cia CHLORAMPHENICOL
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00302
(CAT) 		9 THR A  94
PHE A 103
ALA A 105
PHE A 135
ASN A 146
LEU A 160
VAL A 162
TYR A 168
ILE A 172
 None
None
BME  A 536 ( 4.3A)
None
None
None
None
None
None
 0.26A 1claA-1ciaA:
37.2		 1claA-1ciaA:
99.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1efv ELECTRON TRANSFER
FLAVOPROTEIN

(Homo sapiens) 		PF00766
(ETF_alpha)
PF01012
(ETF) 		5 ALA A 188
ALA A  56
LEU A 119
VAL A 123
ILE A  25
 None
 1.15A 1claA-1efvA:
0.0		 1claA-1efvA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus) 		PF03572
(Peptidase_S41)
PF13180
(PDZ_2) 		5 ALA A 195
PHE A 395
ALA A 193
LEU A 219
VAL A 215
 None
 1.28A 1claA-1fc9A:
0.0		 1claA-1fc9A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkg HEXOKINASE A

(Saccharomyces
cerevisiae) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		5 PHE A 210
ASN A 408
LEU A  24
VAL A  27
ILE A 411
 None
 1.22A 1claA-1hkgA:
undetectable		 1claA-1hkgA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htd ATROLYSIN C

(Crotalus atrox) 		PF01421
(Reprolysin) 		5 ALA A 111
LEU A  10
VAL A  37
TYR A  44
ILE A   8
 None
 1.23A 1claA-1htdA:
0.0		 1claA-1htdA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq9 ACTVA-ORF6
MONOOXYGENASE

(Streptomyces
coelicolor) 		PF03992
(ABM) 		5 ALA A  13
PHE A 103
ALA A  49
LEU A  85
ILE A  40
 None
 1.20A 1claA-1lq9A:
0.0		 1claA-1lq9A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 ALA A 316
ALA A 141
LEU A  33
VAL A 111
ILE A  10
 FAD  A 459 ( 3.7A)
FAD  A 459 (-4.5A)
None
None
None
 1.31A 1claA-1lvlA:
0.0		 1claA-1lvlA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhz METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox) 		5 ALA D 171
PHE D 358
ASN D 155
VAL D 220
ILE D 154
 None
 1.31A 1claA-1mhzD:
0.0		 1claA-1mhzD:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n31 L-CYSTEINE/CYSTINE
LYASE C-DES

(Synechocystis
sp. PCC 6714) 		PF00266
(Aminotran_5) 		5 THR A 140
ALA A 146
LEU A 163
VAL A 196
ILE A 179
 None
 1.27A 1claA-1n31A:
0.0		 1claA-1n31A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o20 GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Thermotoga
maritima) 		PF00171
(Aldedh) 		5 THR A 368
ALA A 247
LEU A 261
VAL A 263
ILE A 244
 None
 1.31A 1claA-1o20A:
undetectable		 1claA-1o20A:
19.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pd5 CHLORAMPHENICOL
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00302
(CAT) 		5 THR A  93
PHE A 102
PHE A 134
LEU A 158
VAL A 160
 None
 0.70A 1claA-1pd5A:
32.5		 1claA-1pd5A:
44.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706

(Neisseria
meningitidis) 		PF02578
(Cu-oxidase_4) 		5 ALA A 204
PHE A 173
ALA A 190
VAL A 145
ILE A 213
 None
 1.13A 1claA-1rv9A:
undetectable		 1claA-1rv9A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		5 THR A 478
ALA A 485
PHE A 505
ALA A 699
LEU A 712
 None
 1.33A 1claA-1rw9A:
undetectable		 1claA-1rw9A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s44 CRUSTACYANIN A1
SUBUNIT

(Homarus
gammarus) 		PF00061
(Lipocalin) 		5 THR A 161
PHE A 164
LEU A 108
VAL A 106
ILE A 157
 None
 1.07A 1claA-1s44A:
undetectable		 1claA-1s44A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb8 WBPP

(Pseudomonas
aeruginosa) 		PF01370
(Epimerase) 		5 THR A 269
PHE A 236
ASN A 272
VAL A 224
TYR A 295
 None
 1.13A 1claA-1sb8A:
undetectable		 1claA-1sb8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1un9 DIHYDROXYACETONE
KINASE

(Citrobacter
freundii) 		PF02733
(Dak1)
PF02734
(Dak2) 		5 ALA A 538
PHE A 392
ALA A 480
LEU A 461
ILE A 478
 None
 1.10A 1claA-1un9A:
undetectable		 1claA-1un9A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp5 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE

(Thermotoga
maritima) 		PF00248
(Aldo_ket_red) 		5 THR A 214
ALA A 216
PHE A 191
VAL A   3
TYR A  41
 None
NAP  A 300 (-3.1A)
NAP  A 300 (-4.5A)
None
None
 1.29A 1claA-1vp5A:
undetectable		 1claA-1vp5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvx YFUA

(Yersinia
enterocolitica) 		PF13343
(SBP_bac_6) 		5 ALA A 266
ALA A 102
LEU A  60
VAL A   9
ILE A 252
 None
 1.16A 1claA-1xvxA:
undetectable		 1claA-1xvxA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2am2 UDP-N-ACETYLMURAMOYL
ALANINE-D-GLUTAMYL-L
YSINE-D-ALANYL-D-ALA
NINE LIGASE, MURF
PROTEIN

(Streptococcus
pneumoniae) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		5 ALA A  63
PHE A  59
ALA A  29
VAL A  80
ILE A   8
 None
 1.30A 1claA-2am2A:
undetectable		 1claA-2am2A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF13088
(BNR_2) 		5 ASN A 415
ALA A 421
LEU A 373
VAL A 383
ILE A 416
 None
 1.34A 1claA-2bf6A:
undetectable		 1claA-2bf6A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2n GIANT HEMOGLOBIN,
A2(A5) GLOBIN CHAIN

(Oligobrachia
mashikoi) 		PF00042
(Globin) 		5 THR B 118
ALA B 117
ALA B  17
LEU B  67
VAL B  66
 None
None
None
None
HEM  B 200 ( 3.9A)
 1.29A 1claA-2d2nB:
undetectable		 1claA-2d2nB:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkp PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 5

(Homo sapiens) 		PF00169
(PH) 		5 PHE A  87
ALA A  89
LEU A  67
TYR A  52
ILE A  65
 None
 1.30A 1claA-2dkpA:
undetectable		 1claA-2dkpA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dws COPPER-CONTAINING
NITRITE REDUCTASE

(Rhodobacter
sphaeroides) 		PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3) 		5 ALA A 132
PHE A 155
ALA A 162
LEU A 103
ILE A 105
 None
 1.30A 1claA-2dwsA:
undetectable		 1claA-2dwsA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0z VIRUS-LIKE PARTICLE

(Pyrococcus
furiosus) 		PF04454
(Linocin_M18) 		5 THR A 299
ALA A 297
PHE A 247
ASN A 337
ALA A 301
 None
 1.10A 1claA-2e0zA:
undetectable		 1claA-2e0zA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f02 TAGATOSE-6-PHOSPHATE
KINASE

(Enterococcus
faecalis) 		PF00294
(PfkB) 		5 PHE A 121
ALA A 153
ALA A 128
VAL A  42
ILE A   2
 None
 1.05A 1claA-2f02A:
undetectable		 1claA-2f02A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		5 ALA A 370
ALA A 212
LEU A  69
VAL A 159
ILE A  40
 FAD  A 611 ( 4.0A)
None
None
None
None
 1.33A 1claA-2gmhA:
undetectable		 1claA-2gmhA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i2w PHOSPHOHEPTOSE
ISOMERASE

(Escherichia
coli) 		PF13580
(SIS_2) 		5 ALA A  79
PHE A  41
ALA A  59
LEU A 144
ILE A 179
 None
 1.34A 1claA-2i2wA:
undetectable		 1claA-2i2wA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i99 MU-CRYSTALLIN
HOMOLOG

(Homo sapiens) 		PF02423
(OCD_Mu_crystall) 		5 THR A 287
ALA A 244
ALA A 221
VAL A 191
ILE A 201
 None
 0.90A 1claA-2i99A:
undetectable		 1claA-2i99A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3g RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 7

(Homo sapiens) 		PF00307
(CH) 		5 PHE A 107
PHE A  96
ALA A  43
LEU A  27
VAL A  26
 None
 1.27A 1claA-2l3gA:
undetectable		 1claA-2l3gA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C

(Sulfurisphaera
tokodaii) 		PF01967
(MoaC) 		5 THR A  91
ALA A 104
LEU A  16
VAL A  15
ILE A 144
 None
 1.13A 1claA-2ohdA:
undetectable		 1claA-2ohdA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyt 2-DEHYDROPANTOATE
2-REDUCTASE

(Porphyromonas
gingivalis) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		5 THR A 179
ALA A 185
PHE A 158
ALA A 180
LEU A  35
 None
 1.18A 1claA-2qytA:
undetectable		 1claA-2qytA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbn TERMINASE LARGE
SUBUNIT

(Bacillus phage
SPP1) 		PF17288
(Terminase_3C) 		5 THR A 405
PHE A 409
ALA A 408
VAL A 255
TYR A 313
 None
 1.33A 1claA-2wbnA:
undetectable		 1claA-2wbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xe4 OLIGOPEPTIDASE B

(Leishmania
major) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		5 ALA A 522
PHE A 521
ALA A 556
LEU A 582
ILE A 526
 None
 1.19A 1claA-2xe4A:
undetectable		 1claA-2xe4A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwi ALPHA-/BETA-GALACTOS
IDE
ALPHA-2,3-SIALYLTRAN
SFERASE

(Photobacterium
phosphoreum) 		PF11477
(PM0188) 		5 THR A 119
ALA A 122
PHE A 188
LEU A 223
ILE A 227
 None
 1.02A 1claA-2zwiA:
undetectable		 1claA-2zwiA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afo NADH KINASE POS5

(Saccharomyces
cerevisiae) 		PF01513
(NAD_kinase) 		5 PHE A 182
ALA A 199
LEU A 143
VAL A  70
TYR A  96
 None
MPD  A2002 (-3.7A)
None
None
None
 1.27A 1claA-3afoA:
undetectable		 1claA-3afoA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bee PUTATIVE YFRE
PROTEIN

(Vibrio
parahaemolyticus) 		no annotation 6 THR A 207
ALA A 204
ASN A 193
LEU A 174
VAL A 170
TYR A 160
 None
None
EDO  A 302 (-3.2A)
None
None
None
 1.49A 1claA-3beeA:
undetectable		 1claA-3beeA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh1 UPF0371 PROTEIN
DIP2346

(Corynebacterium
diphtheriae) 		PF08903
(DUF1846) 		5 ALA A 288
PHE A  52
LEU A  33
VAL A 175
ILE A  20
 None
 0.86A 1claA-3bh1A:
undetectable		 1claA-3bh1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5b ISOCITRATE LYASE

(Brucella
abortus) 		PF00463
(ICL) 		5 ALA A  42
ASN A 118
ALA A 168
LEU A  83
ILE A 117
 None
 1.28A 1claA-3e5bA:
undetectable		 1claA-3e5bA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdx PUTATIVE FILAMENT
PROTEIN / UNIVERSAL
STRESS PROTEIN F

(Klebsiella
pneumoniae) 		PF00582
(Usp) 		5 THR A  14
PHE A  13
ALA A 111
VAL A  32
ILE A 109
 ATP  A 301 ( 4.8A)
None
ATP  A 301 (-3.3A)
None
None
 1.22A 1claA-3fdxA:
undetectable		 1claA-3fdxA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbo ZINC
METALLOPROTEINASE
BMOOMPALFA-I

(Bothrops
moojeni) 		PF01421
(Reprolysin) 		5 ALA A 109
LEU A   8
VAL A  35
TYR A  42
ILE A   6
 None
 1.18A 1claA-3gboA:
undetectable		 1claA-3gboA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvz UNCHARACTERIZED
PROTEIN

([Clostridium]
leptum) 		PF02824
(TGS) 		5 ALA A 434
ALA A 420
LEU A 410
VAL A 398
ILE A 408
 None
 1.25A 1claA-3hvzA:
undetectable		 1claA-3hvzA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4e ISOCITRATE LYASE

(Burkholderia
pseudomallei) 		PF00463
(ICL) 		5 ALA A  46
ASN A 122
ALA A 175
LEU A  87
ILE A 121
 None
 1.32A 1claA-3i4eA:
undetectable		 1claA-3i4eA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifq PLAKOGLOBIN

(Homo sapiens) 		PF00514
(Arm) 		5 ALA A 437
ASN A 398
LEU A 361
VAL A 369
ILE A 395
 None
 1.34A 1claA-3ifqA:
undetectable		 1claA-3ifqA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv0 SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		5 PHE A  55
ALA A  58
PHE A  65
ALA A 120
VAL A 187
 None
 0.92A 1claA-3iv0A:
undetectable		 1claA-3iv0A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k5w CARBOHYDRATE KINASE

(Helicobacter
pylori) 		PF01256
(Carb_kinase)
PF03853
(YjeF_N) 		5 ALA A 440
PHE A 259
LEU A 383
VAL A 338
ILE A 391
 None
 1.31A 1claA-3k5wA:
undetectable		 1claA-3k5wA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kh8 MAOC-LIKE
DEHYDRATASE

(Phytophthora
capsici) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		5 THR A 259
PHE A 271
ALA A 273
VAL A  55
ILE A  32
 None
 0.97A 1claA-3kh8A:
undetectable		 1claA-3kh8A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2c PROLIDASE

(unidentified) 		PF01979
(Amidohydro_1) 		5 THR A 224
ALA A 222
LEU A 134
VAL A 166
ILE A 215
 None
None
KCX  A 188 ( 3.9A)
None
None
 1.25A 1claA-3n2cA:
undetectable		 1claA-3n2cA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qm2 PHOSPHOSERINE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF00266
(Aminotran_5) 		5 ALA A  12
ALA A 196
LEU A 180
VAL A 262
ILE A 179
 None
 1.34A 1claA-3qm2A:
undetectable		 1claA-3qm2A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ruc WBGU

(Plesiomonas
shigelloides) 		PF01370
(Epimerase) 		5 THR A 269
PHE A 236
ASN A 272
VAL A 224
TYR A 295
 None
 1.15A 1claA-3rucA:
undetectable		 1claA-3rucA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sc6 DTDP-4-DEHYDRORHAMNO
SE REDUCTASE

(Bacillus
anthracis) 		PF04321
(RmlD_sub_bind) 		5 PHE A 137
ALA A 133
ASN A  80
ALA A  84
ILE A  79
 None
None
None
None
NAP  A 285 (-4.5A)
 1.30A 1claA-3sc6A:
undetectable		 1claA-3sc6A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		5 ALA A 183
ALA A 125
LEU A  43
VAL A 195
ILE A 123
 None
 1.20A 1claA-3sghA:
undetectable		 1claA-3sghA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sun DNA POLYMERASE

(Escherichia
virus RB69) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		5 PHE A 146
ALA A 336
LEU A 298
VAL A 300
ILE A 334
 None
 1.33A 1claA-3sunA:
undetectable		 1claA-3sunA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tjr SHORT CHAIN
DEHYDROGENASE

(Mycobacterium
avium) 		PF00106
(adh_short) 		5 ALA A  78
PHE A  82
ALA A 125
VAL A 178
ILE A 142
 None
 1.31A 1claA-3tjrA:
undetectable		 1claA-3tjrA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uf0 SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Beutenbergia
cavernae) 		PF13561
(adh_short_C2) 		5 ALA A  26
ASN A  91
LEU A 184
VAL A 244
ILE A 141
 None
NAP  A 274 (-3.2A)
None
None
NAP  A 274 (-4.3A)
 1.26A 1claA-3uf0A:
undetectable		 1claA-3uf0A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16

(Homo sapiens) 		PF01419
(Jacalin) 		5 PHE A 128
ALA A 130
LEU A  64
VAL A  54
ILE A 142
 None
 1.32A 1claA-3vzgA:
undetectable		 1claA-3vzgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wg1 GALACTOSIDE-BINDING
LECTIN

(Agrocybe
aegerita) 		PF00337
(Gal-bind_lectin) 		5 THR A  48
PHE A  65
ALA A  64
ASN A  51
VAL A  29
 None
None
LAT  A 201 ( 4.2A)
None
None
 1.33A 1claA-3wg1A:
undetectable		 1claA-3wg1A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyo LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4B

(Mus musculus) 		PF00560
(LRR_1)
PF07679
(I-set)
PF13855
(LRR_8) 		5 THR A 153
ALA A 155
PHE A 132
LEU A 191
ILE A 172
 None
 1.20A 1claA-3zyoA:
undetectable		 1claA-3zyoA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmr RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA

(Bacillus cereus) 		PF00268
(Ribonuc_red_sm) 		5 THR A 182
ALA A 176
ALA A 183
LEU A 107
ILE A 103
 None
 1.19A 1claA-4bmrA:
undetectable		 1claA-4bmrA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bva THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE

(Mus musculus) 		PF02423
(OCD_Mu_crystall) 		5 THR A 286
ALA A 243
ALA A 220
VAL A 190
ILE A 200
 None
 0.88A 1claA-4bvaA:
undetectable		 1claA-4bvaA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmt CHPT PROTEIN

(Caulobacter
vibrioides) 		PF10090
(HPTransfase) 		5 PHE A 105
ALA A 101
PHE A  78
VAL A 174
ILE A 219
 None
 1.32A 1claA-4fmtA:
undetectable		 1claA-4fmtA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE

([Clostridium]
papyrosolvens) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		5 PHE A 372
ALA A 345
LEU A   9
VAL A 301
TYR A 298
 None
 1.04A 1claA-4fmvA:
undetectable		 1claA-4fmvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxr MALONYL COA
SYNTHETASE,
BENZOATE-COA LIGASE
CHIMERIC PROTEIN

(Rhodopseudomonas
palustris;
Paraburkholderia
xenovorans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		5 THR A  60
ALA A  58
LEU A  45
VAL A  44
ILE A 103
 None
None
None
None
MLY  A 102 ( 3.9A)
 1.31A 1claA-4gxrA:
undetectable		 1claA-4gxrA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hva CASPASE-6

(Homo sapiens) 		PF00656
(Peptidase_C14) 		5 ASN A  73
ALA A  69
LEU A 119
VAL A 117
ILE A 229
 None
 1.28A 1claA-4hvaA:
undetectable		 1claA-4hvaA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mxn UNCHARACTERIZED
PROTEIN

(Parabacteroides
merdae) 		PF00295
(Glyco_hydro_28) 		5 ALA A 108
ALA A 104
LEU A 169
VAL A 190
ILE A 122
 None
 1.16A 1claA-4mxnA:
undetectable		 1claA-4mxnA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppm AMINOTRANSFERASE

(Serratia sp.
FS14) 		PF00202
(Aminotran_3) 		5 THR A 620
ALA A 630
LEU A 599
VAL A 602
ILE A 636
 None
 0.99A 1claA-4ppmA:
undetectable		 1claA-4ppmA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvv ADENOSINE KINASE

(Mycobacterium
tuberculosis) 		PF00294
(PfkB) 		6 THR A  99
ALA A 100
PHE A 116
ALA A  70
LEU A  66
VAL A   5
 None
None
HO4  A 401 (-3.6A)
None
None
None
 1.25A 1claA-4pvvA:
undetectable		 1claA-4pvvA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE

(Bradyrhizobium
diazoefficiens) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		5 THR A 770
ALA A 771
LEU A 900
VAL A 903
ILE A 929
 None
 1.23A 1claA-4q73A:
undetectable		 1claA-4q73A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8r PHOSPHATE ABC
TRANSPORTER,
PHOSPHATE-BINDING
PROTEIN

(Clostridium
perfringens) 		PF12849
(PBP_like_2) 		5 THR A 104
PHE A 135
LEU A 113
VAL A  91
ILE A 120
 None
 1.20A 1claA-4q8rA:
undetectable		 1claA-4q8rA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Neisseria
meningitidis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 PHE A 410
ALA A 394
ALA A 257
LEU A  11
VAL A  21
 None
 1.34A 1claA-4qavA:
undetectable		 1claA-4qavA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qaw XYN30D

(Paenibacillus
barcinonensis) 		PF03422
(CBM_6)
PF17189
(Glyco_hydro_30C) 		5 PHE A 374
ALA A 347
LEU A   8
VAL A 303
TYR A 300
 None
 1.02A 1claA-4qawA:
undetectable		 1claA-4qawA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb9 ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN

(Mycolicibacterium
smegmatis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		5 ALA A 109
ALA A 116
LEU A 353
VAL A 318
ILE A 296
 None
 1.27A 1claA-4qb9A:
undetectable		 1claA-4qb9A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnm IMPORTIN SUBUNIT
ALPHA

(Arabidopsis
thaliana) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		5 THR A 400
ALA A 399
ALA A 438
LEU A 381
VAL A 380
 None
 1.06A 1claA-4tnmA:
undetectable		 1claA-4tnmA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ab4 SCP2-THIOLASE LIKE
PROTEIN

(Trypanosoma
brucei) 		no annotation 5 ALA A 388
PHE A 293
LEU A 218
VAL A 216
ILE A   8
 None
 1.28A 1claA-5ab4A:
undetectable		 1claA-5ab4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dwa TYPE-2 RESTRICTION
ENZYME AGEI

(Thalassobius
gelatinovorus) 		no annotation 5 ALA A  50
PHE A  32
ALA A  99
LEU A 197
VAL A 199
 None
 1.17A 1claA-5dwaA:
undetectable		 1claA-5dwaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e02 FRQ-INTERACTING RNA
HELICASE

(Neurospora
crassa) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		5 ALA A 535
PHE A 446
LEU A 235
TYR A 297
ILE A 232
 None
None
None
None
A  C   4 ( 3.6A)
 1.21A 1claA-5e02A:
undetectable		 1claA-5e02A:
11.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gkx UNCHARACTERIZED
PROTEIN

(Thermococcus
onnurineus) 		PF14336
(DUF4392) 		5 THR A  34
PHE A  29
ALA A 207
LEU A 216
VAL A 257
 None
 1.31A 1claA-5gkxA:
undetectable		 1claA-5gkxA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h0i ASPARAGINYL
ENDOPEPTIDASE

(Oldenlandia
affinis) 		PF01650
(Peptidase_C13) 		5 ALA A 409
ASN A 454
ALA A 455
LEU A 427
VAL A 428
 None
 1.22A 1claA-5h0iA:
undetectable		 1claA-5h0iA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmn AAC3-I

(uncultured
bacterium) 		PF00583
(Acetyltransf_1) 		5 THR A  22
PHE A  23
ALA A  26
LEU A 102
ILE A  98
 None
None
COA  A 201 ( 4.6A)
None
COA  A 201 (-4.3A)
 1.32A 1claA-5hmnA:
undetectable		 1claA-5hmnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy3 MRNA
ENDORIBONUCLEASE
LSOA
ANTITOXIN DMD

(Escherichia
coli;
Escherichia
virus T4) 		PF15935
(RnlA_toxin)
PF17587
(Dmd) 		5 THR B  33
ALA B  32
PHE A 239
ALA B  46
ILE B  48
 None
 1.26A 1claA-5hy3B:
undetectable		 1claA-5hy3B:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis) 		PF05853
(BKACE) 		5 ALA A 948
PHE A 965
LEU A 783
VAL A 781
ILE A 875
 None
 1.19A 1claA-5ikzA:
undetectable		 1claA-5ikzA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iq9 10E8V4 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		5 THR A  95
PHE A 100
ALA A  93
VAL A  63
ILE A  69
 None
 1.13A 1claA-5iq9A:
undetectable		 1claA-5iq9A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5klf CARBOHYDRATE BINDING
MODULE E1

(uncultured
bacterium) 		no annotation 5 ALA A  25
PHE A  90
ALA A  17
LEU A  40
VAL A  71
 None
 1.12A 1claA-5klfA:
undetectable		 1claA-5klfA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liv CYTOCHROME P450
CYP260A1,CYTOCHROME
P450 CYP260A1

(Sorangium
cellulosum) 		PF00067
(p450) 		5 PHE A 178
ALA A 179
LEU A 312
VAL A 305
ILE A 316
 None
 1.31A 1claA-5livA:
undetectable		 1claA-5livA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxr RNA-BINDING PROTEIN
7

(Homo sapiens) 		PF00076
(RRM_1) 		5 ALA A  33
PHE A  57
LEU A  75
VAL A  21
ILE A  80
 None
 1.29A 1claA-5lxrA:
undetectable		 1claA-5lxrA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mjk THIOREDOXIN
REDUCTASE

(Lactococcus
lactis) 		PF07992
(Pyr_redox_2) 		5 ALA A 289
ALA A 110
LEU A  33
VAL A  76
ILE A  10
 FAD  A 401 (-3.6A)
None
None
None
None
 1.31A 1claA-5mjkA:
undetectable		 1claA-5mjkA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4c PROLYL
OLIGOPEPTIDASE

(Galerina
marginata) 		no annotation 5 ALA A 523
PHE A 522
ALA A 556
LEU A 582
ILE A 527
 None
 1.29A 1claA-5n4cA:
undetectable		 1claA-5n4cA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5no5 ABYA5

(Verrucosispora) 		no annotation 5 THR A 238
ALA A 239
ALA A 215
LEU A 177
VAL A 180
 None
 1.23A 1claA-5no5A:
undetectable		 1claA-5no5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nus P34

(Chaetomium
thermophilum) 		no annotation 5 PHE A  62
ALA A  61
ASN A  57
LEU A 267
ILE A  54
 None
 1.25A 1claA-5nusA:
undetectable		 1claA-5nusA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE

(Zobellia
galactanivorans) 		no annotation 5 ALA A 163
PHE A 164
ALA A  74
LEU A 109
VAL A 107
 None
 1.08A 1claA-5opqA:
undetectable		 1claA-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot0 L-ASPARAGINASE

(Thermococcus
kodakarensis) 		no annotation 5 THR A 298
ALA A 295
ALA A  94
LEU A 108
ILE A 140
 None
 1.19A 1claA-5ot0A:
undetectable		 1claA-5ot0A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm1 XYLULOKINASE

(Brucella ovis) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		5 THR A 245
PHE A 252
ALA A 240
LEU A 381
VAL A 276
 None
 1.21A 1claA-5vm1A:
undetectable		 1claA-5vm1A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wgx FLAVIN-DEPENDENT
HALOGENASE

(Malbranchea
aurantiaca) 		PF04820
(Trp_halogenase) 		5 ALA A 506
ALA A 423
LEU A 395
VAL A 389
ILE A 397
 None
 1.22A 1claA-5wgxA:
undetectable		 1claA-5wgxA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whz ANTI-HIV CODV-FAB
HEAVY CHAIN

(Homo sapiens) 		no annotation 5 THR H 101
PHE H 118
ALA H  99
VAL H  66
ILE H  72
 None
 1.07A 1claA-5whzH:
undetectable		 1claA-5whzH:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9a CHORISMATE SYNTHASE

(Pseudomonas
aeruginosa) 		no annotation 5 ALA A 327
ALA A 204
LEU A 188
VAL A 185
ILE A 164
 None
 1.29A 1claA-5z9aA:
undetectable		 1claA-5z9aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus) 		no annotation 5 PHE A 190
ASN A 198
ALA A 193
LEU A 168
VAL A 169
 None
 1.31A 1claA-6aunA:
undetectable		 1claA-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c5c 3-DEHYDROQUINATE
SYNTHASE

(Candida
albicans) 		no annotation 5 ALA A 348
ALA A 269
LEU A 386
VAL A 385
ILE A 266
 None
 1.32A 1claA-6c5cA:
undetectable		 1claA-6c5cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ej2 BETA-SECRETASE 1

(Homo sapiens) 		no annotation 5 PHE A 670
ALA A 653
LEU A 643
VAL A 745
ILE A 692
 None
 1.32A 1claA-6ej2A:
undetectable		 1claA-6ej2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f85 CYTOCHROME P450
CYP260A1

(Sorangium
cellulosum) 		no annotation 5 PHE A 128
ALA A 129
LEU A 262
VAL A 255
ILE A 266
 None
 1.31A 1claA-6f85A:
undetectable		 1claA-6f85A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE

(Thermotoga
maritima) 		no annotation 5 THR B 138
PHE B 207
ALA B 160
LEU B 271
VAL B 275
 None
 1.26A 1claA-6fpeB:
undetectable		 1claA-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6h25 -

(-) 		no annotation 5 PHE B 107
ALA B  39
LEU B 228
VAL B 224
ILE B  41
 None
 1.20A 1claA-6h25B:
undetectable		 1claA-6h25B:
undetectable