SIMILAR PATTERNS OF AMINO ACIDS FOR 1CIL_A_ETSA263
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jd0 | CARBONIC ANHYDRASEXII (Homo sapiens) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneAZM A1400 (-3.2A) ZN A 901 ( 3.2A) ZN A 901 ( 3.2A) ZN A 901 ( 3.1A)AZM A1400 (-4.6A)AZM A1400 ( 4.9A)AZM A1400 (-3.9A)AZM A1400 (-3.6A)AZM A1400 (-3.3A)None | 0.32A | 1cilA-1jd0A:36.4 | 1cilA-1jd0A:36.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jd0 | CARBONIC ANHYDRASEXII (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 64HIS A 96VAL A 143LEU A 198THR A 199THR A 200 | None ZN A 901 ( 3.2A)AZM A1400 ( 4.9A)AZM A1400 (-3.9A)AZM A1400 (-3.6A)AZM A1400 (-3.3A) | 1.19A | 1cilA-1jd0A:36.4 | 1cilA-1jd0A:36.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kop | CARBONIC ANHYDRASE (Neisseriagonorrhoeae) |
PF00194(Carb_anhydrase) | 6 | GLN A 69HIS A 92HIS A 94LEU A 176THR A 177THR A 178 | None ZN A 301 ( 3.2A) ZN A 301 ( 3.3A)AZI A 305 (-4.2A)AZI A 305 (-3.4A)AZI A 305 ( 4.2A) | 1.10A | 1cilA-1kopA:29.8 | 1cilA-1kopA:33.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kop | CARBONIC ANHYDRASE (Neisseriagonorrhoeae) |
PF00194(Carb_anhydrase) | 6 | GLN A 69HIS A 94VAL A 113LEU A 176THR A 177THR A 178 | None ZN A 301 ( 3.3A)NoneAZI A 305 (-4.2A)AZI A 305 (-3.4A)AZI A 305 ( 4.2A) | 1.22A | 1cilA-1kopA:29.8 | 1cilA-1kopA:33.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kop | CARBONIC ANHYDRASE (Neisseriagonorrhoeae) |
PF00194(Carb_anhydrase) | 11 | HIS A 66GLN A 90HIS A 92HIS A 94HIS A 111VAL A 113VAL A 123LEU A 176THR A 177THR A 178TRP A 187 | BME A 303 (-3.6A)None ZN A 301 ( 3.2A) ZN A 301 ( 3.3A) ZN A 301 ( 3.2A)NoneNoneAZI A 305 (-4.2A)AZI A 305 (-3.4A)AZI A 305 ( 4.2A)None | 0.34A | 1cilA-1kopA:29.8 | 1cilA-1kopA:33.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 94HIS A 96LEU A 198THR A 199THR A 200 | None ZN A 601 ( 3.3A) ZN A 601 (-3.3A)AZM A 400 (-3.7A)AZM A 400 (-3.6A)AZM A 400 (-3.6A) | 1.08A | 1cilA-1rj6A:37.1 | 1cilA-1rj6A:37.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | None ZN A 601 (-3.3A)AZM A 400 (-4.8A)AZM A 400 (-3.7A)AZM A 400 (-3.6A)AZM A 400 (-3.6A) | 1.14A | 1cilA-1rj6A:37.1 | 1cilA-1rj6A:37.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneAZM A 400 (-4.3A) ZN A 601 ( 3.3A) ZN A 601 (-3.3A) ZN A 601 ( 3.2A)AZM A 400 (-4.8A)NoneAZM A 400 (-3.7A)AZM A 400 (-3.6A)AZM A 400 (-3.6A)None | 0.46A | 1cilA-1rj6A:37.1 | 1cilA-1rj6A:37.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | HIS A 64HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | None ZN A 601 (-3.3A)AZM A 400 (-4.8A)AZM A 400 (-3.7A)AZM A 400 (-3.6A)AZM A 400 (-3.6A) | 1.02A | 1cilA-1rj6A:37.1 | 1cilA-1rj6A:37.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | HIS A 96HIS A 94VAL A 121LEU A 198THR A 199THR A 200 | ZN A 601 (-3.3A) ZN A 601 ( 3.3A)AZM A 400 (-4.8A)AZM A 400 (-3.7A)AZM A 400 (-3.6A)AZM A 400 (-3.6A) | 1.43A | 1cilA-1rj6A:37.1 | 1cilA-1rj6A:37.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1urt | CARBONIC ANHYDRASE V (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 94HIS A 119LEU A 198THR A 199THR A 200 | None ZN A 280 (-3.2A) ZN A 280 (-3.2A)None ZN A 280 ( 4.9A)None | 1.30A | 1cilA-1urtA:37.0 | 1cilA-1urtA:51.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1urt | CARBONIC ANHYDRASE V (Mus musculus) |
PF00194(Carb_anhydrase) | 10 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | None ZN A 280 (-3.2A) ZN A 280 (-3.2A) ZN A 280 (-3.2A)NoneNoneNone ZN A 280 ( 4.9A)NoneNone | 0.29A | 1cilA-1urtA:37.0 | 1cilA-1urtA:51.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1urt | CARBONIC ANHYDRASE V (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | HIS A 119HIS A 96VAL A 143LEU A 198THR A 199THR A 200 | ZN A 280 (-3.2A) ZN A 280 (-3.2A)NoneNone ZN A 280 ( 4.9A)None | 1.33A | 1cilA-1urtA:37.0 | 1cilA-1urtA:51.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y7w | HALOTOLERANTALPHA-TYPE CARBONICANHYDRASE (DCA II) (Dunaliellasalina) |
PF00194(Carb_anhydrase) | 10 | GLN A 113HIS A 115HIS A 117HIS A 135VAL A 137VAL A 153LEU A 216THR A 217THR A 218TRP A 227 | None ZN A 283 ( 3.2A) ZN A 283 (-3.2A) ZN A 283 ( 3.1A)ACY A 279 ( 4.7A)NoneACY A 279 (-4.3A)ACY A 279 (-3.4A)ACY A 279 ( 4.9A)None | 0.21A | 1cilA-1y7wA:26.1 | 1cilA-1y7wA:31.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y7w | HALOTOLERANTALPHA-TYPE CARBONICANHYDRASE (DCA II) (Dunaliellasalina) |
PF00194(Carb_anhydrase) | 6 | HIS A 115HIS A 135LEU A 216THR A 217THR A 218TRP A 227 | ZN A 283 ( 3.2A) ZN A 283 ( 3.1A)ACY A 279 (-4.3A)ACY A 279 (-3.4A)ACY A 279 ( 4.9A)None | 1.50A | 1cilA-1y7wA:26.1 | 1cilA-1y7wA:31.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y7w | HALOTOLERANTALPHA-TYPE CARBONICANHYDRASE (DCA II) (Dunaliellasalina) |
PF00194(Carb_anhydrase) | 5 | HIS A 117VAL A 137LEU A 216THR A 217THR A 218 | ZN A 283 (-3.2A)ACY A 279 ( 4.7A)ACY A 279 (-4.3A)ACY A 279 (-3.4A)ACY A 279 ( 4.9A) | 0.96A | 1cilA-1y7wA:26.1 | 1cilA-1y7wA:31.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2it4 | CARBONIC ANHYDRASE 1 (Homo sapiens) |
PF00194(Carb_anhydrase) | 8 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 143LEU A 198THR A 199TRP A 209 | None ZN A 561 ( 3.2A) ZN A 561 ( 3.2A) ZN A 561 ( 3.1A)PPF A 500 (-4.9A)PPF A 500 (-3.9A)PPF A 500 (-3.6A)None | 0.50A | 1cilA-2it4A:40.8 | 1cilA-2it4A:60.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2it4 | CARBONIC ANHYDRASE 1 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | HIS A 96HIS A 119VAL A 143LEU A 198THR A 199 | ZN A 561 ( 3.2A) ZN A 561 ( 3.1A)PPF A 500 (-4.9A)PPF A 500 (-3.9A)PPF A 500 (-3.6A) | 1.02A | 1cilA-2it4A:40.8 | 1cilA-2it4A:60.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2w2j | CARBONICANHYDRASE-RELATEDPROTEIN (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 87HIS A 118HIS A 141LEU A 222THR A 223TRP A 233 | None CL A 401 (-4.2A) CL A 401 (-4.1A)None CL A 401 ( 4.8A)None | 0.30A | 1cilA-2w2jA:37.1 | 1cilA-2w2jA:38.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96VAL A 121LEU A 198THR A 199 | None ZN A 1 ( 3.3A) ZN A 1 ( 3.3A)NoneNone ZN A 1 ( 4.7A) | 1.46A | 1cilA-2zncA:32.3 | 1cilA-2zncA:35.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneNone ZN A 1 ( 3.3A) ZN A 1 ( 3.3A) ZN A 1 ( 3.2A)NoneNoneNone ZN A 1 ( 4.7A)NoneNone | 0.32A | 1cilA-2zncA:32.3 | 1cilA-2zncA:35.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | HIS A 64HIS A 96VAL A 143LEU A 198THR A 199THR A 200 | None ZN A 1 ( 3.3A)NoneNone ZN A 1 ( 4.7A)None | 1.15A | 1cilA-2zncA:32.3 | 1cilA-2zncA:35.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 5 | HIS A 94HIS A 96VAL A 121LEU A 198THR A 200 | ZN A 1 ( 3.3A) ZN A 1 ( 3.3A)NoneNoneNone | 1.13A | 1cilA-2zncA:32.3 | 1cilA-2zncA:35.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | HIS A 119HIS A 96VAL A 143LEU A 198THR A 199THR A 200 | ZN A 1 ( 3.2A) ZN A 1 ( 3.3A)NoneNone ZN A 1 ( 4.7A)None | 1.31A | 1cilA-2zncA:32.3 | 1cilA-2zncA:35.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 7 | GLN A 115HIS A 163HIS A 165HIS A 182LEU A 259THR A 260THR A 261 | None ZN A 378 (-3.2A) ZN A 378 (-3.3A) ZN A 378 (-3.1A)None ZN A 378 ( 4.5A)None | 1.03A | 1cilA-3b1bA:24.9 | 1cilA-3b1bA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 6 | GLN A 115HIS A 165VAL A 184LEU A 259THR A 260THR A 261 | None ZN A 378 (-3.3A)NoneNone ZN A 378 ( 4.5A)None | 1.18A | 1cilA-3b1bA:24.9 | 1cilA-3b1bA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 11 | HIS A 112GLN A 161HIS A 163HIS A 165HIS A 182VAL A 184VAL A 201LEU A 259THR A 260THR A 261TRP A 270 | NoneNone ZN A 378 (-3.2A) ZN A 378 (-3.3A) ZN A 378 (-3.1A)NoneNoneNone ZN A 378 ( 4.5A)NoneNone | 0.25A | 1cilA-3b1bA:24.9 | 1cilA-3b1bA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4q | PREDICTEDGLYCOSYLTRANSFERASES (Corynebacteriumglutamicum) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 5 | HIS A 107HIS A 109VAL A 3LEU A 35THR A 31 | None | 1.18A | 1cilA-3c4qA:undetectable | 1cilA-3c4qA:21.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 65GLN A 93HIS A 95HIS A 97LEU A 199THR A 200 | None4MD A 401 (-3.1A) ZN A 301 ( 3.6A) ZN A 301 ( 3.5A)4MD A 401 (-4.2A)4MD A 401 (-3.2A) | 0.89A | 1cilA-3da2A:42.1 | 1cilA-3da2A:59.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 65GLN A 93HIS A 97PHE A 132LEU A 199THR A 200 | None4MD A 401 (-3.1A) ZN A 301 ( 3.5A)4MD A 401 (-4.6A)4MD A 401 (-4.2A)4MD A 401 (-3.2A) | 0.89A | 1cilA-3da2A:42.1 | 1cilA-3da2A:59.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 9 | HIS A 65HIS A 95HIS A 97HIS A 120VAL A 122VAL A 144LEU A 199THR A 200TRP A 210 | None ZN A 301 ( 3.6A) ZN A 301 ( 3.5A) ZN A 301 ( 3.2A)4MD A 401 ( 4.6A)4MD A 401 ( 4.4A)4MD A 401 (-4.2A)4MD A 401 (-3.2A)None | 0.42A | 1cilA-3da2A:42.1 | 1cilA-3da2A:59.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 9 | HIS A 65HIS A 97HIS A 120VAL A 122PHE A 132VAL A 144LEU A 199THR A 200TRP A 210 | None ZN A 301 ( 3.5A) ZN A 301 ( 3.2A)4MD A 401 ( 4.6A)4MD A 401 (-4.6A)4MD A 401 ( 4.4A)4MD A 401 (-4.2A)4MD A 401 (-3.2A)None | 0.29A | 1cilA-3da2A:42.1 | 1cilA-3da2A:59.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0l | GUANINE DEAMINASE (Homo sapiens) |
PF01979(Amidohydro_1) | 5 | GLN A 87HIS A 84HIS A 82PHE A 108VAL A 169 | None ZN A1452 (-3.1A) ZN A1452 (-3.3A)NoneNone | 1.07A | 1cilA-3e0lA:undetectable | 1cilA-3e0lA:20.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fe4 | CARBONIC ANHYDRASE 6 (Homo sapiens) |
PF00194(Carb_anhydrase) | 10 | HIS A 85GLN A 109HIS A 111HIS A 113HIS A 138VAL A 140VAL A 161LEU A 219THR A 220TRP A 230 | NoneNone MG A 901 (-3.4A) MG A 901 (-3.4A) MG A 901 (-3.2A)NoneNoneNoneNoneNone | 0.71A | 1cilA-3fe4A:31.5 | 1cilA-3fe4A:34.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fe4 | CARBONIC ANHYDRASE 6 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 111HIS A 113VAL A 140VAL A 161LEU A 219THR A 220 | MG A 901 (-3.4A) MG A 901 (-3.4A)NoneNoneNoneNone | 1.45A | 1cilA-3fe4A:31.5 | 1cilA-3fe4A:34.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l2h | PUTATIVE SUGARPHOSPHATE ISOMERASE (Acidithiobacillusferrooxidans) |
PF07883(Cupin_2) | 5 | HIS A 104HIS A 62VAL A 71VAL A 118THR A 59 | EDO A 167 (-4.0A)EDO A 167 (-4.2A)NoneEDO A 167 ( 4.9A)EDO A 167 ( 3.9A) | 1.18A | 1cilA-3l2hA:undetectable | 1cilA-3l2hA:23.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 94HIS A 96LEU A 198THR A 199THR A 200 | None ZN A 263 ( 3.2A) ZN A 263 ( 3.2A)AZM A 264 (-3.4A)AZM A 264 (-3.4A)AZM A 264 (-3.5A) | 1.09A | 1cilA-3ml5A:42.6 | 1cilA-3ml5A:55.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | None ZN A 263 ( 3.2A)AZM A 264 (-4.7A)AZM A 264 (-3.4A)AZM A 264 (-3.4A)AZM A 264 (-3.5A) | 1.23A | 1cilA-3ml5A:42.6 | 1cilA-3ml5A:55.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 7 | GLN A 92HIS A 94HIS A 96VAL A 121PHE A 131LEU A 198THR A 199 | AZM A 264 (-4.1A) ZN A 263 ( 3.2A) ZN A 263 ( 3.2A)AZM A 264 (-4.7A)AZM A 264 (-4.4A)AZM A 264 (-3.4A)AZM A 264 (-3.4A) | 1.37A | 1cilA-3ml5A:42.6 | 1cilA-3ml5A:55.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 8 | HIS A 2GLN A 92VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneAZM A 264 (-4.1A)AZM A 264 (-4.7A)AZM A 264 ( 4.9A)AZM A 264 (-3.4A)AZM A 264 (-3.4A)AZM A 264 (-3.5A)None | 1.19A | 1cilA-3ml5A:42.6 | 1cilA-3ml5A:55.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 12 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneAZM A 264 (-4.1A) ZN A 263 ( 3.2A) ZN A 263 ( 3.2A) ZN A 263 ( 3.1A)AZM A 264 (-4.7A)AZM A 264 (-4.4A)AZM A 264 ( 4.9A)AZM A 264 (-3.4A)AZM A 264 (-3.4A)AZM A 264 (-3.5A)None | 0.39A | 1cilA-3ml5A:42.6 | 1cilA-3ml5A:55.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 6 | GLN A 102HIS A 123HIS A 125HIS A 142THR A 215THR A 216 | None ZN A 1 ( 3.2A) ZN A 1 (-3.3A) ZN A 1 ( 3.2A)MLT A 3 ( 4.3A)MLT A 3 (-2.8A) | 1.06A | 1cilA-3q31A:24.3 | 1cilA-3q31A:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 5 | GLN A 102HIS A 125VAL A 144THR A 215THR A 216 | None ZN A 1 (-3.3A)NoneMLT A 3 ( 4.3A)MLT A 3 (-2.8A) | 1.11A | 1cilA-3q31A:24.3 | 1cilA-3q31A:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 10 | GLN A 121HIS A 123HIS A 125HIS A 142VAL A 144VAL A 154LEU A 214THR A 215THR A 216TRP A 225 | MLT A 3 (-3.9A) ZN A 1 ( 3.2A) ZN A 1 (-3.3A) ZN A 1 ( 3.2A)NoneMLT A 3 (-4.6A)MLT A 3 ( 4.2A)MLT A 3 ( 4.3A)MLT A 3 (-2.8A)MLT A 3 (-4.9A) | 0.40A | 1cilA-3q31A:24.3 | 1cilA-3q31A:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 6 | GLN A 121HIS A 123HIS A 125VAL A 144LEU A 214THR A 215 | MLT A 3 (-3.9A) ZN A 1 ( 3.2A) ZN A 1 (-3.3A)NoneMLT A 3 ( 4.2A)MLT A 3 ( 4.3A) | 1.41A | 1cilA-3q31A:24.3 | 1cilA-3q31A:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 6 | HIS A 123HIS A 142VAL A 154LEU A 214THR A 216TRP A 225 | ZN A 1 ( 3.2A) ZN A 1 ( 3.2A)MLT A 3 (-4.6A)MLT A 3 ( 4.2A)MLT A 3 (-2.8A)MLT A 3 (-4.9A) | 1.46A | 1cilA-3q31A:24.3 | 1cilA-3q31A:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uyq | CARBONIC ANHYDRASE 3 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96VAL A 121PHE A 130THR A 198 | None ZN A 261 (-3.3A) ZN A 261 (-3.3A)NoneNone ZN A 261 ( 4.4A) | 1.20A | 1cilA-3uyqA:41.0 | 1cilA-3uyqA:58.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uyq | CARBONIC ANHYDRASE 3 (Homo sapiens) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 130VAL A 142THR A 198THR A 199TRP A 208 | NoneNone ZN A 261 (-3.3A) ZN A 261 (-3.3A) ZN A 261 (-3.2A)NoneNoneNone ZN A 261 ( 4.4A)NoneNone | 0.44A | 1cilA-3uyqA:41.0 | 1cilA-3uyqA:58.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4g7a | CARBONATEDEHYDRATASE (Sulfurihydrogenibiumsp. YO3AOP1) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 91VAL A 110LEU A 173THR A 174THR A 175 | None ZN A 301 ( 3.2A)AZM A 302 (-4.7A)AZM A 302 (-3.8A)AZM A 302 (-3.4A)AZM A 302 (-3.4A) | 1.28A | 1cilA-4g7aA:30.0 | 1cilA-4g7aA:34.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4g7a | CARBONATEDEHYDRATASE (Sulfurihydrogenibiumsp. YO3AOP1) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 87HIS A 89HIS A 91HIS A 108VAL A 110VAL A 120LEU A 173THR A 174THR A 175TRP A 184 | NoneAZM A 302 (-4.4A) ZN A 301 ( 3.2A) ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)AZM A 302 (-4.7A)AZM A 302 ( 4.8A)AZM A 302 (-3.8A)AZM A 302 (-3.4A)AZM A 302 (-3.4A)None | 0.27A | 1cilA-4g7aA:30.0 | 1cilA-4g7aA:34.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4g7a | CARBONATEDEHYDRATASE (Sulfurihydrogenibiumsp. YO3AOP1) |
PF00194(Carb_anhydrase) | 6 | HIS A 91HIS A 89VAL A 110LEU A 173THR A 174THR A 175 | ZN A 301 ( 3.2A) ZN A 301 ( 3.2A)AZM A 302 (-4.7A)AZM A 302 (-3.8A)AZM A 302 (-3.4A)AZM A 302 (-3.4A) | 1.42A | 1cilA-4g7aA:30.0 | 1cilA-4g7aA:34.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqs | HYPOTHETICAL PROTEIN (Bacteroidesuniformis) |
PF06283(ThuA) | 5 | HIS A 120HIS A 48HIS A 234PHE A 216TRP A 148 | None | 0.66A | 1cilA-4jqsA:undetectable | 1cilA-4jqsA:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 11 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | None ZN A 301 (-3.2A) ZN A 301 (-3.2A) ZN A 301 (-3.1A)NoneNoneNoneNone ZN A 301 ( 4.4A)NoneNone | 0.31A | 1cilA-4qk3A:43.4 | 1cilA-4qk3A:95.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 7 | GLN A 92HIS A 94HIS A 96VAL A 121PHE A 131LEU A 198THR A 199 | None ZN A 301 (-3.2A) ZN A 301 (-3.2A)NoneNoneNone ZN A 301 ( 4.4A) | 1.38A | 1cilA-4qk3A:43.4 | 1cilA-4qk3A:95.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 94HIS A 119LEU A 198THR A 199THR A 200TRP A 209 | ZN A 301 (-3.2A) ZN A 301 (-3.1A)None ZN A 301 ( 4.4A)NoneNone | 1.46A | 1cilA-4qk3A:43.4 | 1cilA-4qk3A:95.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | ZN A 301 (-3.2A)NoneNone ZN A 301 ( 4.4A)None | 0.94A | 1cilA-4qk3A:43.4 | 1cilA-4qk3A:95.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4twl | DIOSCORIN 5 (Dioscoreajaponica) |
PF00194(Carb_anhydrase) | 5 | HIS A 97VAL A 116VAL A 126THR A 183TRP A 193 | ASC A 303 (-4.4A)ASC A 303 (-4.2A)ASC A 303 ( 4.5A)ASC A 303 (-3.4A)ASC A 303 (-4.3A) | 0.36A | 1cilA-4twlA:28.5 | 1cilA-4twlA:29.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uov | CARBONATEDEHYDRATASE (Thermovibrioammonificans) |
PF00194(Carb_anhydrase) | 10 | GLN A 110HIS A 112HIS A 114HIS A 131VAL A 133VAL A 143LEU A 197THR A 198THR A 199TRP A 208 | CL A 304 ( 3.7A) ZN A 298 (-3.2A) ZN A 298 ( 3.2A) ZN A 298 ( 3.2A)NoneAZM A 299 ( 4.8A)AZM A 299 (-3.8A)AZM A 299 (-3.3A)AZM A 299 (-3.3A)None | 0.33A | 1cilA-4uovA:31.3 | 1cilA-4uovA:36.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uov | CARBONATEDEHYDRATASE (Thermovibrioammonificans) |
PF00194(Carb_anhydrase) | 5 | HIS A 114VAL A 133LEU A 197THR A 198THR A 199 | ZN A 298 ( 3.2A)NoneAZM A 299 (-3.8A)AZM A 299 (-3.3A)AZM A 299 (-3.3A) | 1.10A | 1cilA-4uovA:31.3 | 1cilA-4uovA:36.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 91VAL A 110LEU A 173THR A 174THR A 175 | None ZN A 301 ( 3.2A)AZM A 302 (-4.8A)AZM A 302 (-3.7A)AZM A 302 (-3.3A)AZM A 302 (-3.3A) | 1.26A | 1cilA-4x5sA:29.9 | 1cilA-4x5sA:38.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 87HIS A 89HIS A 91HIS A 108VAL A 110VAL A 120LEU A 173THR A 174THR A 175TRP A 184 | NoneAZM A 302 (-4.3A) ZN A 301 ( 3.1A) ZN A 301 ( 3.2A) ZN A 301 ( 3.2A)AZM A 302 (-4.8A)AZM A 302 ( 4.8A)AZM A 302 (-3.7A)AZM A 302 (-3.3A)AZM A 302 (-3.3A)None | 0.36A | 1cilA-4x5sA:29.9 | 1cilA-4x5sA:38.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 6 | HIS A 64HIS A 91VAL A 110LEU A 173THR A 174THR A 175 | None ZN A 301 ( 3.2A)AZM A 302 (-4.8A)AZM A 302 (-3.7A)AZM A 302 (-3.3A)AZM A 302 (-3.3A) | 1.19A | 1cilA-4x5sA:29.9 | 1cilA-4x5sA:38.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 5 | HIS A 89HIS A 91VAL A 120LEU A 173THR A 175 | ZN A 301 ( 3.1A) ZN A 301 ( 3.2A)AZM A 302 ( 4.8A)AZM A 302 (-3.7A)AZM A 302 (-3.3A) | 1.09A | 1cilA-4x5sA:29.9 | 1cilA-4x5sA:38.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 6 | HIS A 91HIS A 89VAL A 110LEU A 173THR A 174THR A 175 | ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)AZM A 302 (-4.8A)AZM A 302 (-3.7A)AZM A 302 (-3.3A)AZM A 302 (-3.3A) | 1.41A | 1cilA-4x5sA:29.9 | 1cilA-4x5sA:38.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xfw | ALPHA-CARBONICANHYDRASE (Helicobacterpylori) |
PF00194(Carb_anhydrase) | 8 | HIS A 84HIS A 110HIS A 112HIS A 129VAL A 141LEU A 190THR A 191TRP A 201 | None ZN A 301 (-3.3A) ZN A 301 (-3.4A) ZN A 301 ( 3.1A)NoneNone ZN A 301 (-4.3A)None | 0.95A | 1cilA-4xfwA:26.5 | 1cilA-4xfwA:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xfw | ALPHA-CARBONICANHYDRASE (Helicobacterpylori) |
PF00194(Carb_anhydrase) | 6 | HIS A 84HIS A 110HIS A 129LEU A 190THR A 191TRP A 201 | None ZN A 301 (-3.3A) ZN A 301 ( 3.1A)None ZN A 301 (-4.3A)None | 1.48A | 1cilA-4xfwA:26.5 | 1cilA-4xfwA:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xfw | ALPHA-CARBONICANHYDRASE (Helicobacterpylori) |
PF00194(Carb_anhydrase) | 8 | HIS A 85HIS A 110HIS A 112HIS A 129VAL A 131VAL A 141THR A 191TRP A 201 | None ZN A 301 (-3.3A) ZN A 301 (-3.4A) ZN A 301 ( 3.1A)NoneNone ZN A 301 (-4.3A)None | 0.79A | 1cilA-4xfwA:26.5 | 1cilA-4xfwA:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xfw | ALPHA-CARBONICANHYDRASE (Helicobacterpylori) |
PF00194(Carb_anhydrase) | 8 | HIS A 110HIS A 112HIS A 129VAL A 131VAL A 141LEU A 190THR A 191TRP A 201 | ZN A 301 (-3.3A) ZN A 301 (-3.4A) ZN A 301 ( 3.1A)NoneNoneNone ZN A 301 (-4.3A)None | 0.45A | 1cilA-4xfwA:26.5 | 1cilA-4xfwA:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xix | CARBONIC ANHYDRASE,ALPHA TYPE (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 6 | GLN A 138HIS A 162VAL A 181LEU A 253THR A 254THR A 255 | None ZN A 401 ( 3.2A)None2HP A 402 (-3.4A)2HP A 402 (-2.9A)2HP A 402 (-3.6A) | 1.05A | 1cilA-4xixA:25.8 | 1cilA-4xixA:33.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xix | CARBONIC ANHYDRASE,ALPHA TYPE (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 11 | HIS A 134GLN A 158HIS A 160HIS A 162HIS A 179VAL A 181VAL A 192LEU A 253THR A 254THR A 255TRP A 264 | NoneNone ZN A 401 ( 3.2A) ZN A 401 ( 3.2A) ZN A 401 ( 3.1A)NoneNone2HP A 402 (-3.4A)2HP A 402 (-2.9A)2HP A 402 (-3.6A)None | 0.34A | 1cilA-4xixA:25.8 | 1cilA-4xixA:33.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xz5 | CARBONIC ANHYDRASE,ALPHA FAMILY (Hydrogenovibriocrunogenus) |
PF00194(Carb_anhydrase) | 11 | HIS A 140GLN A 163HIS A 165HIS A 167HIS A 184VAL A 186VAL A 196LEU A 251THR A 252THR A 253TRP A 262 | NoneNone ZN A 401 ( 3.2A) ZN A 401 ( 3.3A) ZN A 401 ( 3.1A)NoneNoneBCT A 402 (-3.8A)BCT A 402 (-3.7A)BCT A 402 ( 4.4A)None | 0.29A | 1cilA-4xz5A:29.7 | 1cilA-4xz5A:32.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xz5 | CARBONIC ANHYDRASE,ALPHA FAMILY (Hydrogenovibriocrunogenus) |
PF00194(Carb_anhydrase) | 6 | HIS A 167HIS A 184VAL A 196LEU A 251THR A 252THR A 253 | ZN A 401 ( 3.3A) ZN A 401 ( 3.1A)NoneBCT A 402 (-3.8A)BCT A 402 (-3.7A)BCT A 402 ( 4.4A) | 1.03A | 1cilA-4xz5A:29.7 | 1cilA-4xz5A:32.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 94HIS A 96LEU A 198THR A 199THR A 200 | GOL A 303 (-3.4A) ZN A 301 (-3.2A) ZN A 301 ( 3.2A)520 A 302 (-3.6A)520 A 302 (-3.4A)GOL A 303 ( 3.5A) | 1.08A | 1cilA-5cjfA:36.5 | 1cilA-5cjfA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 67HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | GOL A 303 (-3.4A) ZN A 301 ( 3.2A)520 A 302 ( 4.9A)520 A 302 (-3.6A)520 A 302 (-3.4A)GOL A 303 ( 3.5A) | 1.17A | 1cilA-5cjfA:36.5 | 1cilA-5cjfA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 11 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneGOL A 303 (-3.2A) ZN A 301 (-3.2A) ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)520 A 302 ( 4.9A)520 A 302 ( 4.9A)520 A 302 (-3.6A)520 A 302 (-3.4A)GOL A 303 ( 3.5A)None | 0.22A | 1cilA-5cjfA:36.5 | 1cilA-5cjfA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | HIS A 64HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | None ZN A 301 ( 3.2A)520 A 302 ( 4.9A)520 A 302 (-3.6A)520 A 302 (-3.4A)GOL A 303 ( 3.5A) | 1.14A | 1cilA-5cjfA:36.5 | 1cilA-5cjfA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e5u | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE GAMMA (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | HIS A 151PHE A 187LEU A 256THR A 257THR A 258TRP A 267 | None | 0.68A | 1cilA-5e5uA:34.2 | 1cilA-5e5uA:31.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 7 | GLN X 91HIS X 93HIS X 95VAL X 120PHE X 129LEU X 196THR X 197 | None ZN X 301 (-3.2A) ZN X 301 (-3.2A)NoneNoneNone ZN X 301 ( 4.4A) | 1.42A | 1cilA-5eztX:43.9 | 1cilA-5eztX:80.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 12 | HIS X 63GLN X 91HIS X 93HIS X 95HIS X 118VAL X 120PHE X 129VAL X 141LEU X 196THR X 197THR X 198TRP X 207 | NoneNone ZN X 301 (-3.2A) ZN X 301 (-3.2A) ZN X 301 (-3.1A)NoneNoneNoneNone ZN X 301 ( 4.4A)NoneNone | 0.35A | 1cilA-5eztX:43.9 | 1cilA-5eztX:80.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 6 | HIS X 63HIS X 93VAL X 205THR X 197THR X 198TRP X 207 | None ZN X 301 (-3.2A)None ZN X 301 ( 4.4A)NoneNone | 1.38A | 1cilA-5eztX:43.9 | 1cilA-5eztX:80.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 6 | HIS X 63HIS X 95VAL X 120LEU X 196THR X 197THR X 198 | None ZN X 301 (-3.2A)NoneNone ZN X 301 ( 4.4A)None | 1.23A | 1cilA-5eztX:43.9 | 1cilA-5eztX:80.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fx8 | LINOLEATE11-LIPOXYGENASE (Gaeumannomycesavenae) |
PF00305(Lipoxygenase) | 5 | GLN A 287HIS A 290HIS A 294PHE A 347LEU A 336 | None MN A1000 (-3.5A) MN A1000 (-3.3A)NoneNone | 1.14A | 1cilA-5fx8A:undetectable | 1cilA-5fx8A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hly | INHIBIN BETA A CHAIN (Homo sapiens) |
PF00019(TGF_beta)PF00688(TGFb_propeptide) | 5 | HIS A 289VAL A 211PHE A 221VAL A 171LEU A 254 | None | 1.17A | 1cilA-5hlyA:undetectable | 1cilA-5hlyA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hlz | INHIBIN BETA A CHAIN (Homo sapiens) |
PF00688(TGFb_propeptide) | 5 | HIS A 289VAL A 211PHE A 221VAL A 171LEU A 254 | None | 1.18A | 1cilA-5hlzA:undetectable | 1cilA-5hlzA:24.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 6 | GLN A 94HIS A 96HIS A 98VAL A 117LEU A 181THR A 182 | None ZN A 301 (-3.2A) ZN A 301 (-3.2A)NoneNone ZN A 301 ( 4.4A) | 1.46A | 1cilA-5hpjA:29.3 | 1cilA-5hpjA:35.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 11 | HIS A 71GLN A 94HIS A 96HIS A 98HIS A 115VAL A 117VAL A 127LEU A 181THR A 182THR A 183TRP A 192 | NoneNone ZN A 301 (-3.2A) ZN A 301 (-3.2A) ZN A 301 (-3.1A)NoneNoneNone ZN A 301 ( 4.4A)NoneNone | 0.40A | 1cilA-5hpjA:29.3 | 1cilA-5hpjA:35.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 5 | HIS A 98VAL A 117LEU A 181THR A 182THR A 183 | ZN A 301 (-3.2A)NoneNone ZN A 301 ( 4.4A)None | 1.04A | 1cilA-5hpjA:29.3 | 1cilA-5hpjA:35.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 5 | HIS A 115HIS A 96HIS A 98PHE A 177THR A 183 | ZN A 301 (-3.1A) ZN A 301 (-3.2A) ZN A 301 (-3.2A)NoneNone | 1.17A | 1cilA-5hpjA:29.3 | 1cilA-5hpjA:35.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 10 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | EZL A 302 (-4.3A) ZN A 301 ( 3.3A) ZN A 301 ( 3.3A) ZN A 301 ( 3.2A)EZL A 302 (-4.7A)EZL A 302 ( 4.7A)EZL A 302 (-3.5A)EZL A 302 (-3.4A)EZL A 302 (-3.9A)None | 0.32A | 1cilA-5jn9A:33.5 | 1cilA-5jn9A:35.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96VAL A 121LEU A 198THR A 199 | EZL A 302 (-4.3A) ZN A 301 ( 3.3A) ZN A 301 ( 3.3A)EZL A 302 (-4.7A)EZL A 302 (-3.5A)EZL A 302 (-3.4A) | 1.40A | 1cilA-5jn9A:33.5 | 1cilA-5jn9A:35.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | HIS A 64HIS A 96LEU A 198THR A 199THR A 200 | None ZN A 301 ( 3.3A)EZL A 302 (-3.5A)EZL A 302 (-3.4A)EZL A 302 (-3.9A) | 0.85A | 1cilA-5jn9A:33.5 | 1cilA-5jn9A:35.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | HIS A 64HIS A 96VAL A 143LEU A 198THR A 200 | None ZN A 301 ( 3.3A)EZL A 302 ( 4.7A)EZL A 302 (-3.5A)EZL A 302 (-3.9A) | 1.05A | 1cilA-5jn9A:33.5 | 1cilA-5jn9A:35.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | HIS A 94HIS A 96VAL A 143LEU A 198THR A 200 | ZN A 301 ( 3.3A) ZN A 301 ( 3.3A)EZL A 302 ( 4.7A)EZL A 302 (-3.5A)EZL A 302 (-3.9A) | 1.14A | 1cilA-5jn9A:33.5 | 1cilA-5jn9A:35.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | HIS A 96VAL A 121LEU A 198THR A 199THR A 200 | ZN A 301 ( 3.3A)EZL A 302 (-4.7A)EZL A 302 (-3.5A)EZL A 302 (-3.4A)EZL A 302 (-3.9A) | 1.09A | 1cilA-5jn9A:33.5 | 1cilA-5jn9A:35.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zqz | TRIFUNCTIONAL ENZYMESUBUNIT ALPHA,MITOCHONDRIAL (Homo sapiens) |
no annotation | 5 | HIS A 498VAL A 591LEU A 551THR A 548THR A 547 | None | 1.17A | 1cilA-5zqzA:undetectable | 1cilA-5zqzA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eki | CARBONIC ANHYDRASE (Persephonellamarina) |
no annotation | 11 | HIS A 92GLN A 115HIS A 117HIS A 119HIS A 136VAL A 138VAL A 148LEU A 201THR A 202THR A 203TRP A 212 | NoneNone ZN A 301 (-3.3A) ZN A 301 (-3.3A) ZN A 301 (-3.2A)NoneNoneNone ZN A 301 (-4.4A)NoneNone | 0.36A | 1cilA-6ekiA:29.9 | 1cilA-6ekiA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eki | CARBONIC ANHYDRASE (Persephonellamarina) |
no annotation | 7 | HIS A 92HIS A 119HIS A 136LEU A 201THR A 202THR A 203TRP A 212 | None ZN A 301 (-3.3A) ZN A 301 (-3.2A)None ZN A 301 (-4.4A)NoneNone | 1.50A | 1cilA-6ekiA:29.9 | 1cilA-6ekiA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eki | CARBONIC ANHYDRASE (Persephonellamarina) |
no annotation | 6 | HIS A 92HIS A 119VAL A 138LEU A 201THR A 202THR A 203 | None ZN A 301 (-3.3A)NoneNone ZN A 301 (-4.4A)None | 1.14A | 1cilA-6ekiA:29.9 | 1cilA-6ekiA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe1 | CARBONIC ANHYDRASE 9 (Homo sapiens) |
no annotation | 11 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | NoneV14 A 302 (-3.8A) ZN A 301 ( 3.2A) ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)V14 A 302 (-4.7A)NoneV14 A 302 (-3.6A)V14 A 302 (-3.2A)V14 A 302 (-3.5A)None | 0.39A | 1cilA-6fe1A:33.8 | 1cilA-6fe1A:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe1 | CARBONIC ANHYDRASE 9 (Homo sapiens) |
no annotation | 6 | HIS A 64HIS A 96VAL A 143LEU A 198THR A 199THR A 200 | None ZN A 301 ( 3.2A)NoneV14 A 302 (-3.6A)V14 A 302 (-3.2A)V14 A 302 (-3.5A) | 1.24A | 1cilA-6fe1A:33.8 | 1cilA-6fe1A:14.90 |