SIMILAR PATTERNS OF AMINO ACIDS FOR 1CD2_A_FOLA307_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbt FRUCTOSE-2,6-BISPHOS
PHATASE

(Rattus
norvegicus) 		PF00300
(His_Phos_1) 		3 GLU A  84
ILE A  19
ARG A   7
 None
None
PO4  A 300 (-3.9A)
 0.82A 1cd2A-1fbtA:
undetectable		 1cd2A-1fbtA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g82 FIBROBLAST GROWTH
FACTOR 9

(Homo sapiens) 		PF00167
(FGF) 		3 GLU A 199
ILE A  60
ARG A  64
 None
 0.85A 1cd2A-1g82A:
undetectable		 1cd2A-1g82A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		3 GLU A  73
ILE A  72
ARG A 260
 None
 0.81A 1cd2A-1g8pA:
0.4		 1cd2A-1g8pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		3 GLU A 157
ILE A 160
ARG A 177
 None
 0.66A 1cd2A-1g8pA:
0.4		 1cd2A-1g8pA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5p PESTICIDIAL CRYSTAL
PROTEIN CRY2AA

(Bacillus
thuringiensis) 		PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
PF09131
(Endotoxin_mid) 		3 GLU A 254
ILE A 258
ARG A 548
 None
 0.67A 1cd2A-1i5pA:
undetectable		 1cd2A-1i5pA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		3 GLU A1123
ILE A1126
ARG A1094
 None
None
B12  A1248 ( 4.9A)
 0.82A 1cd2A-1k7yA:
0.0		 1cd2A-1k7yA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvf SYNTAXIN 6

(Rattus
norvegicus) 		PF09177
(Syntaxin-6_N) 		3 GLU A  72
ILE A  68
ARG A  96
 None
 0.81A 1cd2A-1lvfA:
undetectable		 1cd2A-1lvfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m3s HYPOTHETICAL PROTEIN
YCKF

(Bacillus
subtilis) 		PF01380
(SIS) 		3 GLU A  13
ILE A  10
ARG A  46
 None
 0.57A 1cd2A-1m3sA:
undetectable		 1cd2A-1m3sA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)

(Homo sapiens) 		PF02223
(Thymidylate_kin) 		3 GLU A 185
ILE A 184
ARG A  24
 None
ANP  A 303 ( 4.6A)
ADP  A 302 ( 4.9A)
 0.79A 1cd2A-1nmyA:
0.7		 1cd2A-1nmyA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pmr DIHYDROLIPOYL
SUCCINYLTRANSFERASE

(Escherichia
coli) 		PF00364
(Biotin_lipoyl) 		3 GLU A  61
ILE A  72
ARG A  70
 None
 0.82A 1cd2A-1pmrA:
undetectable		 1cd2A-1pmrA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ru3 ACETYL-COA SYNTHASE

(Carboxydothermus
hydrogenoformans) 		PF03598
(CdhC) 		3 GLU A 482
ILE A 483
ARG A 491
 None
 0.84A 1cd2A-1ru3A:
0.1		 1cd2A-1ru3A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 GLU A 629
ILE A 480
ARG A 190
 None
 0.76A 1cd2A-1w99A:
undetectable		 1cd2A-1w99A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4w GLYCEROL KINASE

(Cellulomonas
sp.) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 GLU A 113
ILE A 110
ARG A 151
 None
 0.78A 1cd2A-2d4wA:
undetectable		 1cd2A-2d4wA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgo CYTOTOXIC
GRANULE-ASSOCIATED
RNA BINDING PROTEIN
1

(Mus musculus) 		PF00076
(RRM_1) 		3 GLU A 133
ILE A 136
ARG A 156
 None
 0.79A 1cd2A-2dgoA:
undetectable		 1cd2A-2dgoA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fsr ACETYLTRANSFERASE

(Agrobacterium
fabrum) 		PF13302
(Acetyltransf_3) 		3 GLU A  75
ILE A  77
ARG A  34
 None
 0.64A 1cd2A-2fsrA:
undetectable		 1cd2A-2fsrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsk VITAMIN B12
TRANSPORTER BTUB

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 GLU A 108
ILE A 130
ARG A 255
 None
 0.75A 1cd2A-2gskA:
undetectable		 1cd2A-2gskA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ije GUANINE
NUCLEOTIDE-RELEASING
PROTEIN

(Mus musculus) 		PF00617
(RasGEF) 		3 GLU S1216
ILE S1213
ARG S1160
 None
 0.59A 1cd2A-2ijeS:
undetectable		 1cd2A-2ijeS:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inc TOLUENE, O-XYLENE
MONOOXYGENASE
OXYGENASE SUBUNIT

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox)
PF04945
(YHS) 		3 GLU A 104
ILE A 227
ARG A 233
 FE  A 501 (-2.6A)
None
None
 0.70A 1cd2A-2incA:
undetectable		 1cd2A-2incA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j28 50S RIBOSOMAL
PROTEIN L2

(Escherichia
coli) 		PF00181
(Ribosomal_L2)
PF03947
(Ribosomal_L2_C) 		3 GLU C  81
ILE C  90
ARG C  62
 None
None
G  B1817 ( 2.6A)
 0.61A 1cd2A-2j28C:
undetectable		 1cd2A-2j28C:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3z C2 TOXIN COMPONENT I

(Clostridium
botulinum) 		PF03496
(ADPrib_exo_Tox) 		3 GLU A  69
ILE A  68
ARG A  86
 None
SO4  A1437 (-3.7A)
SO4  A1437 (-2.8A)
 0.82A 1cd2A-2j3zA:
undetectable		 1cd2A-2j3zA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j8x URACIL-DNA
GLYCOSYLASE

(Human
gammaherpesvirus
4) 		PF03167
(UDG) 		3 GLU A  68
ILE A  52
ARG A  57
 None
 0.70A 1cd2A-2j8xA:
undetectable		 1cd2A-2j8xA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kdi UBIQUITIN, VACUOLAR
PROTEIN
SORTING-ASSOCIATED
PROTEIN 27 FUSION
PROTEIN

(Saccharomyces
cerevisiae) 		PF00240
(ubiquitin)
PF02809
(UIM) 		3 GLU A  43
ILE A  39
ARG A  81
 None
 0.84A 1cd2A-2kdiA:
undetectable		 1cd2A-2kdiA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1v ENDOPLASMIN

(Canis lupus) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		3 GLU A 224
ILE A 210
ARG A 237
 None
 0.81A 1cd2A-2o1vA:
undetectable		 1cd2A-2o1vA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5n MUHV1GPM153

(Murid
betaherpesvirus
1) 		PF11624
(M157) 		3 GLU A  21
ILE A  23
ARG A 113
 None
 0.79A 1cd2A-2o5nA:
undetectable		 1cd2A-2o5nA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5t PEZT

(Streptococcus
pneumoniae) 		PF06414
(Zeta_toxin) 		3 GLU B 160
ILE B 156
ARG B 205
 None
 0.73A 1cd2A-2p5tB:
undetectable		 1cd2A-2p5tB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfw CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN

(Shewanella
frigidimarina) 		PF07883
(Cupin_2) 		3 GLU A  16
ILE A  18
ARG A 107
 None
 0.78A 1cd2A-2pfwA:
undetectable		 1cd2A-2pfwA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1

(Pyrococcus
abyssi) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		3 GLU A 168
ILE A 167
ARG A  21
 None
 0.82A 1cd2A-2pnzA:
undetectable		 1cd2A-2pnzA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v84 SPERMIDINE/PUTRESCIN
E ABC TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN

(Treponema
pallidum) 		PF13416
(SBP_bac_8) 		3 GLU A 313
ILE A 312
ARG A  71
 None
 0.72A 1cd2A-2v84A:
undetectable		 1cd2A-2v84A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsu P-HYDROXYCINNAMOYL
COA HYDRATASE/LYASE

(Pseudomonas
fluorescens) 		PF00378
(ECH_1) 		3 GLU C  84
ILE C  85
ARG C  92
 None
 0.71A 1cd2A-2vsuC:
undetectable		 1cd2A-2vsuC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whl BETA-MANNANASE

(Salipaludibacillus
agaradhaerens) 		PF00150
(Cellulase) 		3 GLU A 117
ILE A 114
ARG A  70
 None
 0.76A 1cd2A-2whlA:
undetectable		 1cd2A-2whlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wse PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II,
CHLOROPLASTIC
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IV A,
CHLOROPLASTIC

(Spinacia
oleracea;
Arabidopsis
thaliana) 		PF02531
(PsaD)
PF02427
(PSI_PsaE) 		3 GLU E  42
ILE D 137
ARG E  62
 None
 0.76A 1cd2A-2wseE:
undetectable		 1cd2A-2wseE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu0 PHYTASE

(Klebsiella
pneumoniae) 		PF00328
(His_Phos_2) 		3 GLU A  39
ILE A  38
ARG A  28
 None
None
SO4  A1409 ( 4.0A)
 0.85A 1cd2A-2wu0A:
undetectable		 1cd2A-2wu0A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzq PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780

(Pyrococcus
horikoshii) 		PF00571
(CBS) 		3 GLU A 253
ILE A 252
ARG A 180
 SAM  A6075 (-3.0A)
SAM  A6075 (-3.6A)
SAM  A6075 (-3.5A)
 0.76A 1cd2A-2yzqA:
undetectable		 1cd2A-2yzqA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxh TRNA URIDINE
5-CARBOXYMETHYLAMINO
METHYL MODIFICATION
ENZYME MNMG

(Aquifex
aeolicus) 		PF01134
(GIDA)
PF13932
(GIDA_assoc) 		3 GLU A 217
ILE A 251
ARG A  97
 None
 0.85A 1cd2A-2zxhA:
undetectable		 1cd2A-2zxhA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		3 GLU A3273
ILE A3268
ARG A3085
 None
 0.66A 1cd2A-3cmvA:
2.6		 1cd2A-3cmvA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cp2 TRNA URIDINE
5-CARBOXYMETHYLAMINO
METHYL MODIFICATION
ENZYME GIDA

(Escherichia
coli) 		PF01134
(GIDA)
PF13932
(GIDA_assoc) 		3 GLU A 474
ILE A 473
ARG A 465
 None
 0.66A 1cd2A-3cp2A:
undetectable		 1cd2A-3cp2A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cq0 PUTATIVE
TRANSALDOLASE
YGR043C

(Saccharomyces
cerevisiae) 		PF00923
(TAL_FSA) 		3 GLU A 330
ILE A  82
ARG A 112
 None
None
GOL  A 352 ( 3.6A)
 0.85A 1cd2A-3cq0A:
undetectable		 1cd2A-3cq0A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d36 SPORULATION KINASE B
SPORULATION KINASE
INHIBITOR SDA

(Geobacillus
stearothermophilus;
Geobacillus
stearothermophilus) 		PF00512
(HisKA)
PF02518
(HATPase_c)
PF08970
(Sda) 		3 GLU A 249
ILE A 245
ARG C  36
 None
 0.82A 1cd2A-3d36A:
undetectable		 1cd2A-3d36A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddd PUTATIVE
ACETYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF00583
(Acetyltransf_1) 		3 GLU A  12
ILE A  11
ARG A 174
 None
 0.76A 1cd2A-3dddA:
undetectable		 1cd2A-3dddA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd7 FUSION COMPLEX OF
CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR, RESIDUES
1193-1427 AND
MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK,
RESIDUES 219-371

(Escherichia
coli;
Homo sapiens) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 GLU A1405
ILE A1404
ARG A1495
 None
 0.69A 1cd2A-3gd7A:
1.9		 1cd2A-3gd7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Salmonella
enterica) 		PF02540
(NAD_synthase) 		3 GLU A  20
ILE A  23
ARG A 186
 None
 0.82A 1cd2A-3hmqA:
1.6		 1cd2A-3hmqA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j47 26S PROTEASOME
REGULATORY SUBUNIT
RPN8

(Saccharomyces
cerevisiae) 		PF13012
(MitMem_reg) 		3 GLU U 272
ILE U 276
ARG U 189
 None
 0.84A 1cd2A-3j47U:
undetectable		 1cd2A-3j47U:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jap EIF3A

(Saccharomyces
cerevisiae) 		PF00411
(Ribosomal_S11) 		3 GLU o 101
ILE o 104
ARG o 195
 None
 0.74A 1cd2A-3japo:
undetectable		 1cd2A-3japo:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jug BETA-MANNANASE

(Bacillus sp.
N16-5) 		PF00150
(Cellulase) 		3 GLU A 148
ILE A 145
ARG A 101
 None
 0.85A 1cd2A-3jugA:
undetectable		 1cd2A-3jugA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3la2 GLOBAL NITROGEN
REGULATOR

(Nostoc sp. PCC
7120) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		3 GLU A 106
ILE A 105
ARG A  88
 None
None
AKG  A 224 (-3.8A)
 0.85A 1cd2A-3la2A:
undetectable		 1cd2A-3la2A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcq THIAMINE-MONOPHOSPHA
TE KINASE

(Methylobacillus
flagellatus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		3 GLU A 246
ILE A 249
ARG A 170
 None
 0.74A 1cd2A-3mcqA:
undetectable		 1cd2A-3mcqA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0g ISOPRENE SYNTHASE

(Populus tremula
x Populus alba) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 GLU A 257
ILE A 256
ARG A 249
 None
 0.82A 1cd2A-3n0gA:
undetectable		 1cd2A-3n0gA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3q MMOQ

(Methylococcus
capsulatus) 		PF08668
(HDOD) 		3 GLU A 191
ILE A 188
ARG A 204
 None
 0.78A 1cd2A-3p3qA:
undetectable		 1cd2A-3p3qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qk3 BETA-CRYSTALLIN B3

(Homo sapiens) 		PF00030
(Crystall) 		3 GLU A  82
ILE A 197
ARG A 105
 None
 0.78A 1cd2A-3qk3A:
undetectable		 1cd2A-3qk3A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rim TRANSKETOLASE

(Mycobacterium
tuberculosis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 GLU A 668
ILE A 667
ARG A 522
 None
 0.71A 1cd2A-3rimA:
undetectable		 1cd2A-3rimA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 GLU A 564
ILE A 560
ARG A 370
 None
 0.61A 1cd2A-3s9vA:
undetectable		 1cd2A-3s9vA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdq ALPHA-BISABOLENE
SYNTHASE

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 GLU A 509
ILE A 505
ARG A 315
 None
 0.65A 1cd2A-3sdqA:
undetectable		 1cd2A-3sdqA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu2 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME,
CHLOROPLASTIC/AMYLOP
LASTIC

(Oryza sativa) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 GLU A 413
ILE A  13
ARG A 455
 None
 0.85A 1cd2A-3vu2A:
undetectable		 1cd2A-3vu2A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6q TYROSINASE

(Aspergillus
oryzae) 		PF00264
(Tyrosinase) 		3 GLU A 447
ILE A 444
ARG A 429
 None
 0.75A 1cd2A-3w6qA:
undetectable		 1cd2A-3w6qA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfo POLY A POLYMERASE

(Aquifex
aeolicus) 		PF01743
(PolyA_pol)
PF01966
(HD)
PF12627
(PolyA_pol_RNAbd) 		3 GLU A  86
ILE A  97
ARG A 132
 None
 0.73A 1cd2A-3wfoA:
undetectable		 1cd2A-3wfoA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aip FE-REGULATED PROTEIN
B

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 GLU A 447
ILE A 449
ARG A  62
 None
 0.74A 1cd2A-4aipA:
undetectable		 1cd2A-4aipA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
ALPHA

(Methanothermobacter
marburgensis) 		PF00374
(NiFeSe_Hases) 		3 GLU A 325
ILE A 324
ARG A 219
 None
 0.66A 1cd2A-4ci0A:
undetectable		 1cd2A-4ci0A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cyd PROBABLE
TRANSCRIPTION
REGULATOR

(Corynebacterium
glutamicum) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		3 GLU A   6
ILE A   7
ARG A 163
 None
 0.67A 1cd2A-4cydA:
undetectable		 1cd2A-4cydA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4da5 CHOLINE KINASE ALPHA

(Homo sapiens) 		PF01633
(Choline_kinase) 		3 GLU A 227
ILE A 224
ARG A 212
 None
 0.78A 1cd2A-4da5A:
undetectable		 1cd2A-4da5A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpk MALONYL-COA/SUCCINYL
-COA REDUCTASE

(Sulfurisphaera
tokodaii) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 GLU A  96
ILE A 147
ARG A 216
 None
 0.85A 1cd2A-4dpkA:
undetectable		 1cd2A-4dpkA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e0b MALATE DEHYDROGENASE

(Vibrio
vulnificus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 GLU A 155
ILE A 152
ARG A  23
 ACT  A 401 (-3.4A)
None
None
 0.74A 1cd2A-4e0bA:
undetectable		 1cd2A-4e0bA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdg MINICHROMOSOME
MAINTENANCE PROTEIN
MCM

(Sulfolobus
solfataricus) 		no annotation 3 GLU B 160
ILE B 190
ARG B  99
 None
 0.85A 1cd2A-4fdgB:
undetectable		 1cd2A-4fdgB:
14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4g8z DIHYDROFOLATE
REDUCTASE

(Pneumocystis
jirovecii) 		PF00186
(DHFR_1) 		3 GLU X  32
ILE X  33
ARG X  75
 TOP  X 301 (-3.0A)
TOP  X 301 ( 4.4A)
None
 0.46A 1cd2A-4g8zX:
34.5		 1cd2A-4g8zX:
95.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		3 GLU M 434
ILE M 433
ARG M 679
 None
 0.55A 1cd2A-4gq2M:
undetectable		 1cd2A-4gq2M:
13.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4h96 DIHYDROFOLATE
REDUCTASE

(Candida
albicans) 		PF00186
(DHFR_1) 		3 GLU A  32
ILE A  33
ARG A  72
 14Q  A 202 (-2.8A)
14Q  A 202 ( 4.0A)
None
 0.72A 1cd2A-4h96A:
24.0		 1cd2A-4h96A:
38.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsc STREPTOLYSIN O

(Streptococcus
pyogenes) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		3 GLU X 492
ILE X 494
ARG X 524
 None
 0.80A 1cd2A-4hscX:
undetectable		 1cd2A-4hscX:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imd N-ACETYLNEURAMINATE
LYASE

(Pasteurella
multocida) 		PF00701
(DHDPS) 		3 GLU A  73
ILE A  74
ARG A 217
 None
 0.79A 1cd2A-4imdA:
undetectable		 1cd2A-4imdA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4isy CYSTEINE DESULFURASE

(Mycobacterium
tuberculosis) 		PF00266
(Aminotran_5) 		3 GLU A  45
ILE A  44
ARG A 237
 None
 0.83A 1cd2A-4isyA:
0.9		 1cd2A-4isyA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mgu STRUCTURAL PROTEIN
VP2

(Orthopteran
ambidensovirus
1) 		PF02336
(Denso_VP4) 		3 GLU A 324
ILE A 323
ARG A  82
 None
 0.63A 1cd2A-4mguA:
undetectable		 1cd2A-4mguA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n2x DL-2-HALOACID
DEHALOGENASE

(Methylobacterium
sp. CPA1) 		PF10778
(DehI) 		3 GLU A 169
ILE A 168
ARG A  43
 None
 0.54A 1cd2A-4n2xA:
undetectable		 1cd2A-4n2xA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ncn EUKARYOTIC
TRANSLATION
INITIATION FACTOR
5B-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		3 GLU A 552
ILE A 556
ARG A 605
 MG  A1002 ( 4.0A)
GTP  A1001 ( 3.7A)
None
 0.66A 1cd2A-4ncnA:
undetectable		 1cd2A-4ncnA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A

(Pseudomonas
mendocina) 		PF02332
(Phenol_Hydrox) 		3 GLU A 104
ILE A 227
ARG A 233
 FE  A 501 ( 2.4A)
None
None
 0.81A 1cd2A-4p1cA:
undetectable		 1cd2A-4p1cA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2p NA(+)/H(+) EXCHANGE
REGULATORY COFACTOR
NHE-RF3

(Homo sapiens) 		PF00595
(PDZ) 		3 GLU A 182
ILE A 181
ARG A 134
 None
 0.83A 1cd2A-4q2pA:
undetectable		 1cd2A-4q2pA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlr CYTOCHROME C, 1
HEME-BINDING SITE

(Geobacter
sulfurreducens) 		no annotation 3 GLU A 121
ILE A 117
ARG A  68
 None
 0.77A 1cd2A-4rlrA:
undetectable		 1cd2A-4rlrA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzz PEPTIDASE M24

(Ruegeria
lacuscaerulensis) 		PF00557
(Peptidase_M24) 		3 GLU A 261
ILE A 299
ARG A 204
 None
 0.79A 1cd2A-4rzzA:
undetectable		 1cd2A-4rzzA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmz EIF5B

(Chaetomium
thermophilum) 		no annotation 3 GLU B 552
ILE B 556
ARG B 605
 MG  B 902 ( 3.9A)
GSP  B 901 (-4.2A)
None
 0.71A 1cd2A-4tmzB:
undetectable		 1cd2A-4tmzB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tw5 EPS1P

(Saccharomyces
cerevisiae) 		PF00085
(Thioredoxin) 		3 GLU A  80
ILE A 134
ARG A 139
 None
 0.83A 1cd2A-4tw5A:
undetectable		 1cd2A-4tw5A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd9 NISIN BIOSYNTHESIS
PROTEIN NISB

(Lactococcus
lactis) 		PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C) 		3 GLU A 496
ILE A 514
ARG A 477
 None
 0.83A 1cd2A-4wd9A:
undetectable		 1cd2A-4wd9A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woq N-ACETYLNEURAMINATE
LYASE

(Clostridioides
difficile) 		PF00701
(DHDPS) 		3 GLU A  84
ILE A  85
ARG A 228
 None
 0.74A 1cd2A-4woqA:
undetectable		 1cd2A-4woqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xfe TRAP DICARBOXYLATE
TRANSPORTER SUBUNIT
DCTP

(Pseudomonas
putida) 		PF03480
(DctP) 		3 GLU A  31
ILE A  32
ARG A 149
 None
BDP  A 401 ( 4.5A)
BDP  A 401 (-2.9A)
 0.67A 1cd2A-4xfeA:
undetectable		 1cd2A-4xfeA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa5 NIFE-HYDROGENASE
SMALL SUBUNIT, HOFK
NIFE-HYDROGENASE
LARGE SUBUNIT, HOFG

(Cupriavidus
necator;
Cupriavidus
necator) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
PF00374
(NiFeSe_Hases) 		3 GLU A 127
ILE A 123
ARG C 364
 None
 0.82A 1cd2A-5aa5A:
undetectable		 1cd2A-5aa5A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aor DOSAGE COMPENSATION
REGULATOR

(Drosophila
melanogaster) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind) 		3 GLU A1054
ILE A1056
ARG A 739
 None
None
U  C   5 ( 3.0A)
 0.84A 1cd2A-5aorA:
undetectable		 1cd2A-5aorA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7z LACTOYLGLUTATHIONE
LYASE

(Zea mays) 		PF00903
(Glyoxalase) 		3 GLU A 288
ILE A 262
ARG A 254
 None
 0.69A 1cd2A-5d7zA:
undetectable		 1cd2A-5d7zA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 GLU A 264
ILE A 266
ARG A 526
 None
 0.74A 1cd2A-5eawA:
undetectable		 1cd2A-5eawA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ftg CHOLINE KINASE ALPHA

(Homo sapiens) 		PF01633
(Choline_kinase) 		3 GLU A 227
ILE A 224
ARG A 212
 None
 0.81A 1cd2A-5ftgA:
undetectable		 1cd2A-5ftgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gte LACHRYMATORY-FACTOR
SYNTHASE

(Allium cepa) 		PF10604
(Polyketide_cyc2) 		3 GLU A 158
ILE A 159
ARG A  71
 None
 0.75A 1cd2A-5gteA:
undetectable		 1cd2A-5gteA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)

(Naja atra) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		3 GLU A 580
ILE A 606
ARG A 646
 None
 0.80A 1cd2A-5gz4A:
undetectable		 1cd2A-5gz4A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jj2 A-KINASE ANCHOR
PROTEIN 7 ISOFORM
GAMMA

(Homo sapiens) 		PF10469
(AKAP7_NLS) 		3 GLU A 140
ILE A 208
ARG A  80
 None
 0.78A 1cd2A-5jj2A:
undetectable		 1cd2A-5jj2A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0u CAPSID PROTEIN VP1
CAPSID PROTEIN VP3

(Rhinovirus C;
Rhinovirus C) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU B  79
ILE B  81
ARG A 273
 None
 0.81A 1cd2A-5k0uB:
undetectable		 1cd2A-5k0uB:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 GLU A 125
ILE A 147
ARG A 296
 None
 0.77A 1cd2A-5mzsA:
undetectable		 1cd2A-5mzsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		3 GLU T2876
ILE T2877
ARG T2885
 None
 0.79A 1cd2A-5ojsT:
undetectable		 1cd2A-5ojsT:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol8 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 GLU A 352
ILE A 348
ARG A 293
 None
 0.82A 1cd2A-5ol8A:
undetectable		 1cd2A-5ol8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 GLU A 352
ILE A 348
ARG A 293
 None
 0.82A 1cd2A-5olaA:
undetectable		 1cd2A-5olaA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vae ACCESSORY SEC SYSTEM
PROTEIN ASP1

(Streptococcus
gordonii) 		no annotation 3 GLU A 375
ILE A 378
ARG A 410
 None
 0.72A 1cd2A-5vaeA:
undetectable		 1cd2A-5vaeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgj PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM

(Homo sapiens) 		no annotation 3 GLU A 722
ILE A 718
ARG A  38
 None
 0.82A 1cd2A-5xgjA:
undetectable		 1cd2A-5xgjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Komagataella
phaffii) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 GLU B 694
ILE B 609
ARG B 398
 None
 0.85A 1cd2A-5xogB:
undetectable		 1cd2A-5xogB:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B
ALTERNATIVE COMPLEX
III SUBUNIT D

(Flavobacterium
johnsoniae;
Flavobacterium
johnsoniae) 		no annotation
no annotation 		3 GLU B 856
ILE D  84
ARG B 878
 None
 0.63A 1cd2A-6btmB:
undetectable		 1cd2A-6btmB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eic MYCOBACTERIUM
TUBERCULOSIS
MONOGLYCERIDE LIPASE

(Mycobacterium
tuberculosis) 		no annotation 3 GLU C 250
ILE C 231
ARG C 236
 None
 0.84A 1cd2A-6eicC:
undetectable		 1cd2A-6eicC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Sus scrofa) 		no annotation 3 GLU B 669
ILE B 604
ARG B 392
 None
 0.81A 1cd2A-6exvB:
undetectable		 1cd2A-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 3 GLU A2583
ILE A2581
ARG A1928
 None
 0.65A 1cd2A-6fb3A:
undetectable		 1cd2A-6fb3A:
undetectable