SIMILAR PATTERNS OF AMINO ACIDS FOR 1C8L_A_CFFA940
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aor | ALDEHYDE FERREDOXINOXIDOREDUCTASE (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 4 | ASN A 260PHE A 261ALA A 352GLY A 349 | None | 0.98A | 1c8lA-1aorA:undetectable | 1c8lA-1aorA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ayz | UBIQUITIN-CONJUGATING ENZYME RAD6 (Saccharomycescerevisiae) |
PF00179(UQ_con) | 4 | ASN A 114HIS A 78GLY A 42TYR A 48 | None | 1.10A | 1c8lA-1ayzA:undetectable | 1c8lA-1ayzA:11.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1e4o | MALTODEXTRINPHOSPHORYLASE (Escherichiacoli) |
PF00343(Phosphorylase) | 4 | HIS A 536ALA A 575GLY A 577TYR A 578 | GLC A 995 (-4.4A)GLC A 995 (-3.5A)NoneGLC A 995 (-3.8A) | 0.73A | 1c8lA-1e4oA:51.0 | 1c8lA-1e4oA:42.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ig8 | HEXOKINASE PII (Saccharomycescerevisiae) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | ASN A 267ALA A 239GLY A 238TYR A 240 | None | 1.14A | 1c8lA-1ig8A:0.9 | 1c8lA-1ig8A:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1omo | ALANINEDEHYDROGENASE (Archaeoglobusfulgidus) |
PF02423(OCD_Mu_crystall) | 4 | ASN A 214PHE A 288ALA A 117GLY A 114 | ASN A 214 ( 0.6A)PHE A 288 ( 1.3A)ALA A 117 ( 0.0A)GLY A 114 ( 0.0A) | 1.08A | 1c8lA-1omoA:undetectable | 1c8lA-1omoA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ope | SUCCINYL-COA:3-KETOACID-COENZYME ATRANSFERASE (Sus scrofa) |
PF01144(CoA_trans) | 4 | ASN A 51PHE A 25GLY A 385TYR A 76 | None | 1.13A | 1c8lA-1opeA:undetectable | 1c8lA-1opeA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjz | ENDOGLUCANASE (Thermotogamaritima) |
PF00150(Cellulase) | 4 | PHE A 30ALA A 34GLY A 78TYR A 77 | None | 1.10A | 1c8lA-1vjzA:0.4 | 1c8lA-1vjzA:15.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | HIS A 571ALA A 610GLY A 612TYR A 613 | None | 0.67A | 1c8lA-1ygpA:45.8 | 1c8lA-1ygpA:48.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zef | ALKALINE PHOSPHATASE (Homo sapiens) |
PF00245(Alk_phosphatase) | 4 | ASN A 84PHE A 107ALA A 94GLY A 93 | NonePHE A 802 (-4.4A)NoneSEP A 92 ( 2.4A) | 1.03A | 1c8lA-1zefA:undetectable | 1c8lA-1zefA:20.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 4 | HIS A 525ALA A 564GLY A 566TYR A 567 | None | 0.75A | 1c8lA-2c4mA:50.2 | 1c8lA-2c4mA:43.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb9 | FENGYCIN SYNTHETASE (Bacillussubtilis) |
PF00975(Thioesterase) | 4 | HIS A 201ALA A 112GLY A 82TYR A 83 | ACY A1225 (-3.9A)NoneNoneNone | 1.08A | 1c8lA-2cb9A:6.0 | 1c8lA-2cb9A:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3a | GLUTAMINE SYNTHETASE (Zea mays) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 4 | HIS A 280ALA A 283GLY A 285TYR A 284 | None | 1.07A | 1c8lA-2d3aA:0.1 | 1c8lA-2d3aA:18.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gj4 | GLYCOGENPHOSPHORYLASE,MUSCLE FORM (Oryctolaguscuniculus) |
PF00343(Phosphorylase) | 6 | ASN A 282PHE A 285HIS A 571ALA A 610GLY A 612TYR A 613 | None | 0.52A | 1c8lA-2gj4A:55.6 | 1c8lA-2gj4A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmh | ELECTRON TRANSFERFLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE (Sus scrofa) |
PF05187(ETF_QO)PF13450(NAD_binding_8) | 4 | HIS A 216ALA A 332GLY A 239TYR A 238 | None | 0.93A | 1c8lA-2gmhA:undetectable | 1c8lA-2gmhA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i00 | ACETYLTRANSFERASE,GNAT FAMILY (Enterococcusfaecalis) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 4 | ASN A 247ALA A 250GLY A 227TYR A 245 | None | 1.14A | 1c8lA-2i00A:undetectable | 1c8lA-2i00A:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ox4 | PUTATIVE MANDELATERACEMASE (Zymomonasmobilis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASN A 120ALA A 332GLY A 117TYR A 113 | NoneNoneGOL A3414 (-3.8A)None | 0.98A | 1c8lA-2ox4A:2.1 | 1c8lA-2ox4A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r3v | MEVALONATE KINASE (Homo sapiens) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | ASN A 205PHE A 190ALA A 189GLY A 192 | None | 1.13A | 1c8lA-2r3vA:1.6 | 1c8lA-2r3vA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rdy | BH0842 PROTEIN (Bacillushalodurans) |
PF14498(Glyco_hyd_65N_2) | 4 | HIS A 421ALA A 409GLY A 414TYR A 413 | None | 1.11A | 1c8lA-2rdyA:2.4 | 1c8lA-2rdyA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv8 | FATTY ACID SYNTHASESUBUNIT BETA (FAS1) (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF01575(MaoC_dehydratas)PF08354(DUF1729)PF13452(MaoC_dehydrat_N)PF16073(SAT) | 4 | ASN G 153HIS G 500ALA G 148GLY G 150 | None | 0.98A | 1c8lA-2uv8G:0.0 | 1c8lA-2uv8G:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7y | CHAPERONE PROTEINDNAK (Geobacilluskaustophilus) |
PF00012(HSP70) | 4 | ASN A 121PHE A 120ALA A 123GLY A 72 | None | 1.12A | 1c8lA-2v7yA:undetectable | 1c8lA-2v7yA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2veo | LIPASE A (Moesziomycesantarcticus) |
PF03583(LIP) | 4 | HIS A 366ALA A 187GLY A 182TYR A 183 | None | 1.14A | 1c8lA-2veoA:undetectable | 1c8lA-2veoA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0q | ALCALIGINBIOSYNTHESIS PROTEIN (Bordetellabronchiseptica) |
PF04183(IucA_IucC)PF06276(FhuF) | 4 | PHE A 174HIS A 130GLY A 181TYR A 179 | None | 1.12A | 1c8lA-2x0qA:undetectable | 1c8lA-2x0qA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y8d | ERYTHROCYTE MEMBRANEPROTEIN 1 (Plasmodiumfalciparum) |
PF05424(Duffy_binding) | 4 | ASN A2352ALA A2410GLY A2412TYR A2411 | None | 0.94A | 1c8lA-2y8dA:undetectable | 1c8lA-2y8dA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3k | LEUCYL/PHENYLALANYL-TRNA-PROTEINTRANSFERASE (Escherichiacoli) |
PF03588(Leu_Phe_trans) | 4 | PHE A 47ALA A 41GLY A 45TYR A 42 | None | 1.06A | 1c8lA-2z3kA:undetectable | 1c8lA-2z3kA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z8z | LIPASE (Pseudomonas sp.MIS38) |
PF00353(HemolysinCabind) | 4 | ASN A 344ALA A 317GLY A 319TYR A 318 | None | 0.86A | 1c8lA-2z8zA:undetectable | 1c8lA-2z8zA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zt9 | CYTOCHROME B6CYTOCHROME B6-FCOMPLEX SUBUNIT 5 (Nostoc sp. PCC7120) |
PF00033(Cytochrome_B)PF02529(PetG) | 4 | ASN A 31ALA G 24GLY G 20TYR G 23 | NoneNoneBCR G 101 (-3.4A)BCR G 101 (-3.7A) | 1.00A | 1c8lA-2zt9A:undetectable | 1c8lA-2zt9A:13.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ail | 303AA LONGHYPOTHETICALESTERASE (Sulfurisphaeratokodaii) |
PF07859(Abhydrolase_3) | 4 | ASN A 254ALA A 251GLY A 249TYR A 252 | None | 1.14A | 1c8lA-3ailA:5.5 | 1c8lA-3ailA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b5e | MLL8374 PROTEIN (Mesorhizobiumjaponicum) |
no annotation | 4 | ASN A 122HIS A 198GLY A 116TYR A 117 | EDO A 229 (-3.2A)NoneNoneEDO A 232 (-4.6A) | 1.12A | 1c8lA-3b5eA:undetectable | 1c8lA-3b5eA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bws | PROTEIN LP49 (Leptospirainterrogans) |
PF10282(Lactonase) | 4 | ASN A 435HIS A 136GLY A 379TYR A 381 | None | 0.91A | 1c8lA-3bwsA:undetectable | 1c8lA-3bwsA:19.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 6 | ASN A 282PHE A 285HIS A 571ALA A 610GLY A 612TYR A 613 | None | 0.78A | 1c8lA-3cemA:67.4 | 1c8lA-3cemA:80.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f44 | PUTATIVEMONOOXYGENASE (Lactobacillusacidophilus) |
PF03992(ABM) | 4 | ASN A 173ALA A 176GLY A 149TYR A 171 | None | 1.12A | 1c8lA-3f44A:undetectable | 1c8lA-3f44A:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcr | PUTATIVEAMINOTRANSFERASE (Ruegeria sp.TM1040) |
PF00202(Aminotran_3) | 4 | ASN A 126HIS A 322ALA A 122GLY A 299 | None | 1.13A | 1c8lA-3fcrA:undetectable | 1c8lA-3fcrA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcr | PUTATIVEAMINOTRANSFERASE (Ruegeria sp.TM1040) |
PF00202(Aminotran_3) | 4 | ASN A 126HIS A 322GLY A 299TYR A 114 | None | 1.12A | 1c8lA-3fcrA:undetectable | 1c8lA-3fcrA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7n | LIPASE (Penicilliumexpansum) |
PF01764(Lipase_3) | 4 | ASN A 185HIS A 131ALA A 243GLY A 246 | None | 1.09A | 1c8lA-3g7nA:2.6 | 1c8lA-3g7nA:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gju | PUTATIVEAMINOTRANSFERASE (Mesorhizobiumjaponicum) |
PF00202(Aminotran_3) | 4 | ASN A 127HIS A 323GLY A 300TYR A 115 | None | 1.13A | 1c8lA-3gjuA:undetectable | 1c8lA-3gjuA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gl1 | HEAT SHOCK PROTEINSSB1 (Saccharomycescerevisiae) |
PF00012(HSP70) | 4 | ASN A 153PHE A 152ALA A 155GLY A 77 | None | 1.08A | 1c8lA-3gl1A:undetectable | 1c8lA-3gl1A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnq | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE, TYPEI (Burkholderiapseudomallei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 290PHE A 287ALA A 292GLY A 276 | None | 0.83A | 1c8lA-3gnqA:2.8 | 1c8lA-3gnqA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4j | AMINOTRANSFERASE,CLASS III (Deinococcusradiodurans) |
PF00202(Aminotran_3) | 4 | ASN A 171ALA A 210GLY A 212TYR A 213 | None | 0.91A | 1c8lA-3i4jA:undetectable | 1c8lA-3i4jA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i7j | BETA-LACTAMASEMB2281C (Mycobacteriumbovis) |
PF00144(Beta-lactamase) | 4 | ASN A 198HIS A 213GLY A 193TYR A 192 | None | 1.14A | 1c8lA-3i7jA:undetectable | 1c8lA-3i7jA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll7 | PUTATIVEMETHYLTRANSFERASE (Porphyromonasgingivalis) |
no annotation | 4 | PHE A 269HIS A 295ALA A 301GLY A 302 | NoneFMT A 504 ( 4.1A)NoneNone | 1.04A | 1c8lA-3ll7A:undetectable | 1c8lA-3ll7A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p24 | BFT-3 (Bacteroidesfragilis) |
PF13583(Reprolysin_4)PF16376(fragilysinNterm) | 4 | ASN A 357HIS A 348ALA A 356GLY A 355 | None ZN A 999 (-3.2A)NoneNone | 1.00A | 1c8lA-3p24A:undetectable | 1c8lA-3p24A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3phg | SHIKIMATEDEHYDROGENASE (Helicobacterpylori) |
PF08501(Shikimate_dh_N) | 4 | HIS A 15ALA A 209GLY A 230TYR A 210 | None | 1.02A | 1c8lA-3phgA:2.7 | 1c8lA-3phgA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfw | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE/OXYGENASE LARGE SUBUNIT (Rhodopseudomonaspalustris) |
PF00016(RuBisCO_large) | 4 | ASN A 192HIS A 153ALA A 156GLY A 159 | None | 1.11A | 1c8lA-3qfwA:undetectable | 1c8lA-3qfwA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qj3 | CATHEPSIN L-LIKEPROTEIN (Tenebriomolitor) |
PF00112(Peptidase_C1)PF08246(Inhibitor_I29) | 4 | ASN A 287PHE A 299GLY A 248TYR A 250 | None | 1.11A | 1c8lA-3qj3A:undetectable | 1c8lA-3qj3A:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qml | 78 KDAGLUCOSE-REGULATEDPROTEIN HOMOLOG (Saccharomycescerevisiae) |
PF00012(HSP70) | 4 | ASN A 197PHE A 196ALA A 199GLY A 121 | None | 1.12A | 1c8lA-3qmlA:undetectable | 1c8lA-3qmlA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qyg | CO-TYPE NITRILEHYDRATASE BETASUBUNIT (Pseudomonasputida) |
PF02211(NHase_beta) | 4 | ASN B 47HIS B 147ALA B 174GLY B 177 | None | 1.13A | 1c8lA-3qygB:undetectable | 1c8lA-3qygB:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r44 | FATTY ACYL COASYNTHETASE FADD13(FATTY-ACYL-COASYNTHETASE) (Mycobacteriumtuberculosis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ASN A 3ALA A 75GLY A 73TYR A 72 | None | 1.00A | 1c8lA-3r44A:undetectable | 1c8lA-3r44A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4j | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 4 | ASN A 297HIS A 349ALA A 298GLY A 342 | None | 1.08A | 1c8lA-3u4jA:4.8 | 1c8lA-3u4jA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubm | FORMYL-COA:OXALATECOA-TRANSFERASE (Acetobacteraceti) |
PF02515(CoA_transf_3) | 4 | ASN A 72ALA A 33GLY A 36TYR A 35 | None | 1.12A | 1c8lA-3ubmA:2.1 | 1c8lA-3ubmA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bma | UDP-N-ACETYLGLUCOSAMINEPYROPHOSPHORYLASE (Aspergillusfumigatus) |
PF01704(UDPGP) | 4 | ASN A 75ALA A 42GLY A 43TYR A 39 | None | 1.13A | 1c8lA-4bmaA:undetectable | 1c8lA-4bmaA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d72 | GLYCOSIDE HYDROLASE (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 4 | ASN A 591ALA A 595GLY A 593TYR A 560 | NoneNoneNoneNAG A2009 (-4.6A) | 1.11A | 1c8lA-4d72A:undetectable | 1c8lA-4d72A:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h32 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | ASN A 190HIS A 180GLY A 193TYR A 192 | None | 1.09A | 1c8lA-4h32A:undetectable | 1c8lA-4h32A:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpe | PUTATIVE CELL WALLHYDROLASETN916-LIKE,CTN1-ORF17 (Clostridioidesdifficile) |
PF00877(NLPC_P60)PF13702(Lysozyme_like) | 4 | ASN A 139HIS A 155GLY A 141TYR A 144 | GOL A 406 ( 3.9A)NoneNoneNone | 1.10A | 1c8lA-4hpeA:undetectable | 1c8lA-4hpeA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3m | AEROTAXIS TRANSDUCERAER2 (Pseudomonasaeruginosa) |
no annotation | 4 | PHE A 130ALA A 124GLY A 126TYR A 125 | None | 0.96A | 1c8lA-4i3mA:undetectable | 1c8lA-4i3mA:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jlw | GLUTATHIONE-INDEPENDENT FORMALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ASN A 4HIS A 393ALA A 137GLY A 6 | None | 1.14A | 1c8lA-4jlwA:undetectable | 1c8lA-4jlwA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ljs | PERIPLASMIC BINDINGPROTEIN (Veillonellaparvula) |
PF01497(Peripla_BP_2) | 4 | ASN A 69ALA A 155GLY A 129TYR A 153 | None | 1.12A | 1c8lA-4ljsA:undetectable | 1c8lA-4ljsA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lyp | EXO-BETA-1,4-MANNOSIDASE (Rhizomucormiehei) |
no annotation | 4 | ASN A 166PHE A 169ALA A 165TYR A 126 | None | 1.05A | 1c8lA-4lypA:undetectable | 1c8lA-4lypA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nuz | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE F2 (Streptococcuspyogenes) |
no annotation | 4 | ASN A 677PHE A 666GLY A 645TYR A 644 | None | 1.09A | 1c8lA-4nuzA:undetectable | 1c8lA-4nuzA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o5f | TYPE IIIPANTOTHENATE KINASE (Burkholderiathailandensis) |
PF03309(Pan_kinase) | 4 | ASN A 91PHE A 139ALA A 82GLY A 100 | NoneNoneNonePAU A 301 (-3.4A) | 1.06A | 1c8lA-4o5fA:undetectable | 1c8lA-4o5fA:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oah | MITOCHONDRIALDYNAMIC PROTEINMID51 (Mus musculus) |
PF03281(Mab-21) | 4 | ASN A 433HIS A 391GLY A 422TYR A 418 | None | 1.14A | 1c8lA-4oahA:undetectable | 1c8lA-4oahA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rtf | CHAPERONE PROTEINDNAK (Mycobacteriumtuberculosis) |
PF00012(HSP70) | 4 | ASN D 123PHE D 122ALA D 125GLY D 74 | None | 1.14A | 1c8lA-4rtfD:undetectable | 1c8lA-4rtfD:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ryb | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Neisseriameningitidis) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | ASN A 125ALA A 4GLY A 175TYR A 3 | None | 1.10A | 1c8lA-4rybA:undetectable | 1c8lA-4rybA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u0t | ADC-7 BETA-LACTAMASE (Acinetobacterbaumannii) |
PF00144(Beta-lactamase) | 4 | ASN A 79ALA A 251GLY A 74TYR A 76 | None | 1.10A | 1c8lA-4u0tA:undetectable | 1c8lA-4u0tA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uph | SULFATASE (SULFURICESTER HYDROLASE)PROTEIN (Agrobacteriumtumefaciens) |
PF00884(Sulfatase)PF16347(DUF4976) | 4 | PHE A 58ALA A 330GLY A 347TYR A 349 | None | 1.13A | 1c8lA-4uphA:undetectable | 1c8lA-4uphA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjb | PUTATIVEAMIDOHYDROLASE/PEPTIDASE (Burkholderiacenocepacia) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | PHE A 292ALA A 265GLY A 258TYR A 261 | None | 0.97A | 1c8lA-4wjbA:undetectable | 1c8lA-4wjbA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wqt | RNA CLEAVAGESTIMULATING FACTOR(GREA/GFH1 CHIMERICPROTEIN GRE-C1) (Thermusthermophilus) |
PF01272(GreA_GreB)PF03449(GreA_GreB_N) | 4 | PHE X 33ALA X 36GLY X 47TYR X 48 | None | 0.99A | 1c8lA-4wqtX:undetectable | 1c8lA-4wqtX:10.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy9 | PUTATIVE MCP-TYPESIGNAL TRANSDUCTIONPROTEIN (Campylobacterjejuni) |
PF02743(dCache_1) | 4 | ASN A 265HIS A 251ALA A 289GLY A 292 | ACT A 401 ( 4.3A)ACT A 401 (-4.0A)ACT A 401 (-3.5A)None | 1.05A | 1c8lA-4wy9A:undetectable | 1c8lA-4wy9A:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgc | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 2ORIGIN RECOGNITIONCOMPLEX SUBUNIT 3 (Drosophilamelanogaster) |
PF04084(ORC2)PF07034(ORC3_N) | 4 | ASN B 484PHE B 351GLY C 317TYR C 320 | None | 1.05A | 1c8lA-4xgcB:undetectable | 1c8lA-4xgcB:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z11 | AURONE SYNTHASE (Coreopsisgrandiflora) |
PF00264(Tyrosinase)PF12142(PPO1_DWL)PF12143(PPO1_KFDV) | 4 | PHE A 273HIS A 286ALA A 276GLY A 271 | None CU A 701 (-3.1A)NoneNone | 1.11A | 1c8lA-4z11A:undetectable | 1c8lA-4z11A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgj | NITRILE HYDRATASEBETA SUBUNIT (Comamonastestosteroni) |
PF02211(NHase_beta) | 4 | ASN B 47HIS B 135ALA B 162GLY B 165 | None | 1.07A | 1c8lA-4zgjB:undetectable | 1c8lA-4zgjB:12.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5af3 | VAPBC49 (Mycobacteriumtuberculosis) |
PF04255(DUF433) | 4 | ASN A 182ALA A 181GLY A 179TYR A 178 | None | 0.99A | 1c8lA-5af3A:undetectable | 1c8lA-5af3A:14.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e84 | 78 KDAGLUCOSE-REGULATEDPROTEIN (Homo sapiens) |
PF00012(HSP70) | 4 | ASN A 177PHE A 176ALA A 179GLY A 100 | None | 1.08A | 1c8lA-5e84A:undetectable | 1c8lA-5e84A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eco | JASMONIC ACID-AMIDOSYNTHETASE JAR1 (Arabidopsisthaliana) |
PF03321(GH3) | 4 | PHE A 223HIS A 229ALA A 221GLY A 303 | None | 1.08A | 1c8lA-5ecoA:undetectable | 1c8lA-5ecoA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fn4 | NICASTRIN (Homo sapiens) |
PF05450(Nicastrin) | 4 | PHE A 448HIS A 449ALA A 442GLY A 366 | None | 1.08A | 1c8lA-5fn4A:undetectable | 1c8lA-5fn4A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fur | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 6 (Homo sapiens) |
PF07571(TAF6_C) | 4 | HIS J 422ALA J 378GLY J 375TYR J 374 | None | 1.13A | 1c8lA-5furJ:undetectable | 1c8lA-5furJ:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gai | TAIL FIBER PROTEIN (Salmonellavirus P22) |
no annotation | 4 | ASN Y 340PHE Y 337HIS Y 427GLY Y 348 | None | 1.05A | 1c8lA-5gaiY:undetectable | 1c8lA-5gaiY:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ghf | AMINOTRANSFERASECLASS-III (Ochrobactrumanthropi) |
PF00202(Aminotran_3) | 4 | ASN A 167HIS A 180ALA A 159GLY A 153 | NoneNoneNonePMP A 501 ( 3.7A) | 1.14A | 1c8lA-5ghfA:undetectable | 1c8lA-5ghfA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h4r | BETA-1,3-1,4-GLUCANASE (Caldicellulosiruptorsp. F32) |
PF00150(Cellulase) | 4 | ASN A 362PHE A 372ALA A 364GLY A 369 | CTT A 401 (-4.0A)CTT A 401 ( 4.5A)NoneNone | 1.07A | 1c8lA-5h4rA:undetectable | 1c8lA-5h4rA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iai | SUGAR ABCTRANSPORTER (Agrobacteriumtumefaciens) |
PF01547(SBP_bac_1) | 4 | PHE A 356HIS A 345ALA A 353GLY A 352 | None | 0.92A | 1c8lA-5iaiA:undetectable | 1c8lA-5iaiA:18.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikp | GLYCOGENPHOSPHORYLASE, BRAINFORM (Homo sapiens) |
PF00343(Phosphorylase) | 4 | HIS A 571ALA A 610GLY A 612TYR A 613 | None | 0.72A | 1c8lA-5ikpA:undetectable | 1c8lA-5ikpA:83.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjo | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF08238(Sel1) | 4 | ASN A 188ALA A 185GLY A 183TYR A 184 | None | 1.13A | 1c8lA-5jjoA:undetectable | 1c8lA-5jjoA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 4 | ASN A 307ALA A 306GLY A 264TYR A 266 | None | 1.07A | 1c8lA-5jlcA:undetectable | 1c8lA-5jlcA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9h | 0940_GH29 (unidentified) |
PF00754(F5_F8_type_C)PF01120(Alpha_L_fucos) | 4 | ASN A 175ALA A 174GLY A 172TYR A 171 | None | 0.91A | 1c8lA-5k9hA:undetectable | 1c8lA-5k9hA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqi | CATALASE-PEROXIDASE (Burkholderiapseudomallei) |
PF00141(peroxidase) | 4 | PHE A 728ALA A 724GLY A 720TYR A 719 | None | 0.99A | 1c8lA-5kqiA:undetectable | 1c8lA-5kqiA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kx4 | 10.7 KDA SALIVARYPROTEIN (Lutzomyialongipalpis) |
no annotation | 4 | ASN A 13PHE A 10ALA A 14TYR A 79 | None | 1.11A | 1c8lA-5kx4A:undetectable | 1c8lA-5kx4A:9.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2p | ARYLESTERASE (Sulfolobussolfataricus) |
PF07859(Abhydrolase_3) | 4 | PHE A 185HIS A 281ALA A 85GLY A 213 | None | 1.02A | 1c8lA-5l2pA:undetectable | 1c8lA-5l2pA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5na4 | NADHDEHYDROGENASE-LIKEPROTEINSAOUHSC_00878 (Staphylococcusaureus) |
no annotation | 4 | PHE A 145ALA A 149GLY A 189TYR A 188 | None | 1.04A | 1c8lA-5na4A:undetectable | 1c8lA-5na4A:7.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5obu | CHAPERONE PROTEINDNAK (Mycoplasmagenitalium) |
no annotation | 4 | ASN A 130PHE A 129ALA A 132GLY A 76 | None | 1.11A | 1c8lA-5obuA:undetectable | 1c8lA-5obuA:7.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5obw | CHAPERONE PROTEINDNAK (Mycoplasmagenitalium) |
no annotation | 4 | ASN A 130PHE A 129ALA A 132GLY A 76 | SO4 A 406 (-4.3A)GOL A 410 (-4.8A)NoneNone | 1.13A | 1c8lA-5obwA:undetectable | 1c8lA-5obwA:7.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5pep | PEPSIN (Sus scrofa) |
PF00026(Asp) | 4 | ASN A 180ALA A 324GLY A 177TYR A 175 | None | 1.02A | 1c8lA-5pepA:undetectable | 1c8lA-5pepA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyq | UNCHARACTERIZEDPROTEIN (Mycobacteriumtuberculosis) |
PF00551(Formyl_trans_N) | 4 | HIS A 12ALA A 140GLY A 136TYR A 139 | NoneNone CL A 307 (-3.6A)0FX A 302 (-3.8A) | 1.11A | 1c8lA-5vyqA:undetectable | 1c8lA-5vyqA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8x | LIPID-A-DISACCHARIDESYNTHASE (Escherichiacoli) |
no annotation | 4 | ASN A 103PHE A 102ALA A 99GLY A 14 | None | 0.78A | 1c8lA-5w8xA:undetectable | 1c8lA-5w8xA:6.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbl | CRISPR-ASSOCIATEDENDONUCLEASECAS9/CSN1 (Streptococcuspyogenes) |
PF13395(HNH_4)PF16592(Cas9_REC)PF16593(Cas9-BH)PF16595(Cas9_PI) | 4 | PHE A 351ALA A 360GLY A 358TYR A 359 | G B 43 ( 4.9A) G B 43 ( 3.4A)None G B 43 ( 4.8A) | 0.84A | 1c8lA-5xblA:undetectable | 1c8lA-5xblA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 4 | ASN A 266PHE A 263ALA A 373GLY A 375 | None | 0.76A | 1c8lA-5xsyA:undetectable | 1c8lA-5xsyA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9d | ACYL-COENZYME AOXIDASE 1 (Yarrowialipolytica) |
no annotation | 4 | ASN A 428PHE A 430ALA A 636GLY A 639 | None | 1.13A | 1c8lA-5y9dA:undetectable | 1c8lA-5y9dA:7.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ys9 | ACYL-COENZYME AOXIDASE 3 (Yarrowialipolytica) |
no annotation | 4 | ASN A 439PHE A 441ALA A 646GLY A 649 | None | 1.07A | 1c8lA-5ys9A:undetectable | 1c8lA-5ys9A:6.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b7p | SDED (Legionellapneumophila) |
no annotation | 4 | PHE A 176HIS A 93GLY A 182TYR A 183 | None | 1.08A | 1c8lA-6b7pA:undetectable | 1c8lA-6b7pA:7.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoe | 78 KDAGLUCOSE-REGULATEDPROTEIN (Cricetulusgriseus) |
no annotation | 4 | ASN A 177PHE A 176ALA A 179GLY A 100 | None | 1.07A | 1c8lA-6eoeA:undetectable | 1c8lA-6eoeA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f74 | ALCOHOL OXIDASE (Thermothelomycesthermophila) |
no annotation | 4 | HIS A 301ALA A 203GLY A 201TYR A 188 | None | 1.03A | 1c8lA-6f74A:undetectable | 1c8lA-6f74A:7.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fyd | PUTATIVEFAD-DEPENDENTOXYGENASE ENCM (Streptomycesmaritimus) |
no annotation | 4 | ASN A 375ALA A 431GLY A 433TYR A 432 | None | 1.05A | 1c8lA-6fydA:undetectable | 1c8lA-6fydA:8.86 |