SIMILAR PATTERNS OF AMINO ACIDS FOR 1BDW_B_DVAB8_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ii2 PHOSPHOENOLPYRUVATE
CARBOXYKINASE


(Trypanosoma
cruzi)
PF01293
(PEPCK_ATP)
3 VAL A 330
VAL A 216
TRP A 411
None
0.91A 1bdwA-1ii2A:
undetectable
1bdwB-1ii2A:
undetectable
1bdwA-1ii2A:
3.38
1bdwB-1ii2A:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmz AMINE DEHYDROGENASE

(Pseudomonas
putida)
PF09098
(Dehyd-heme_bind)
PF09099
(Qn_am_d_aIII)
PF09100
(Qn_am_d_aIV)
PF14930
(Qn_am_d_aII)
3 VAL A 368
VAL A 370
TRP A 398
None
0.98A 1bdwA-1jmzA:
undetectable
1bdwB-1jmzA:
undetectable
1bdwA-1jmzA:
2.23
1bdwB-1jmzA:
2.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN


(Escherichia
coli)
PF01497
(Peripla_BP_2)
3 VAL N  46
VAL N 101
TRP N  43
None
0.96A 1bdwA-1k7sN:
undetectable
1bdwB-1k7sN:
undetectable
1bdwA-1k7sN:
5.05
1bdwB-1k7sN:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE


(Comamonas
testosteroni)
PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3)
3 VAL A  74
VAL A  76
TRP A  29
None
0.93A 1bdwA-1kb0A:
undetectable
1bdwB-1kb0A:
undetectable
1bdwA-1kb0A:
2.73
1bdwB-1kb0A:
2.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqq ALPHA-D-GLUCURONIDAS
E


(Geobacillus
stearothermophilus)
PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M)
3 VAL A  60
VAL A  57
TRP A  68
None
None
GOL  A 756 (-3.8A)
0.99A 1bdwA-1mqqA:
undetectable
1bdwB-1mqqA:
undetectable
1bdwA-1mqqA:
3.46
1bdwB-1mqqA:
3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7d LYSOSOMAL
ALPHA-MANNOSIDASE


(Bos taurus)
PF01074
(Glyco_hydro_38)
3 VAL A 156
VAL A 119
TRP A 155
None
0.92A 1bdwA-1o7dA:
undetectable
1bdwB-1o7dA:
undetectable
1bdwA-1o7dA:
4.71
1bdwB-1o7dA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p22 F-BOX/WD-REPEAT
PROTEIN 1A


(Homo sapiens)
PF00400
(WD40)
PF12937
(F-box-like)
3 VAL A 404
VAL A 395
TRP A 415
None
0.84A 1bdwA-1p22A:
undetectable
1bdwB-1p22A:
undetectable
1bdwA-1p22A:
2.92
1bdwB-1p22A:
2.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE


(Escherichia
coli)
PF13419
(HAD_2)
3 VAL A  57
VAL A  76
TRP A  61
None
0.94A 1bdwA-1te2A:
undetectable
1bdwB-1te2A:
undetectable
1bdwA-1te2A:
8.77
1bdwB-1te2A:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u7g PROBABLE AMMONIUM
TRANSPORTER


(Escherichia
coli)
PF00909
(Ammonium_transp)
3 VAL A 369
VAL A 364
TRP A 135
None
0.89A 1bdwA-1u7gA:
undetectable
1bdwB-1u7gA:
undetectable
1bdwA-1u7gA:
5.19
1bdwB-1u7gA:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhd PUTATIVE
ACETYLTRANSFERASE/AC
YLTRANSFERASE


(Bacillus cereus)
PF00132
(Hexapep)
3 VAL A  57
VAL A  77
TRP A  37
None
0.86A 1bdwA-1xhdA:
undetectable
1bdwB-1xhdA:
undetectable
1bdwA-1xhdA:
9.78
1bdwB-1xhdA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y96 GEM-ASSOCIATED
PROTEIN 6


(Homo sapiens)
PF06372
(Gemin6)
3 VAL A  47
VAL A  45
TRP A  33
None
0.83A 1bdwA-1y96A:
undetectable
1bdwB-1y96A:
undetectable
1bdwA-1y96A:
12.31
1bdwB-1y96A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN


(Alicyclobacillus
acidocaldarius)
PF00005
(ABC_tran)
PF08402
(TOBE_2)
3 VAL A 282
VAL A 280
TRP A 252
None
0.82A 1bdwA-1z47A:
undetectable
1bdwB-1z47A:
undetectable
1bdwA-1z47A:
2.96
1bdwB-1z47A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zag PROTEIN
(ZINC-ALPHA-2-GLYCOP
ROTEIN)


(Homo sapiens)
PF00129
(MHC_I)
PF07654
(C1-set)
3 VAL A 247
VAL A 191
TRP A 245
None
0.96A 1bdwA-1zagA:
undetectable
1bdwB-1zagA:
undetectable
1bdwA-1zagA:
4.38
1bdwB-1zagA:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0h MANNAN
ENDO-1,4-BETA-MANNOS
IDASE


(Mytilus edulis)
PF00150
(Cellulase)
3 VAL A 235
VAL A 237
TRP A 172
None
0.77A 1bdwA-2c0hA:
undetectable
1bdwB-2c0hA:
undetectable
1bdwA-2c0hA:
7.64
1bdwB-2c0hA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1d SOXA

(Paracoccus
denitrificans)
no annotation 3 VAL A 288
VAL A 286
TRP A  65
None
0.96A 1bdwA-2c1dA:
undetectable
1bdwB-2c1dA:
undetectable
1bdwA-2c1dA:
3.82
1bdwB-2c1dA:
3.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ckb ALPHA, BETA T CELL
RECEPTOR


(Mus musculus)
PF07686
(V-set)
PF09291
(DUF1968)
3 VAL A 114
VAL A 112
TRP A  82
None
0.75A 1bdwA-2ckbA:
undetectable
1bdwB-2ckbA:
undetectable
1bdwA-2ckbA:
6.29
1bdwB-2ckbA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvj V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG, ISOFORM A


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
3 VAL A  37
VAL A  51
TRP A  15
None
0.84A 1bdwA-2dvjA:
undetectable
1bdwB-2dvjA:
undetectable
1bdwA-2dvjA:
7.61
1bdwB-2dvjA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
3 VAL A  37
VAL A  51
TRP A  15
None
0.95A 1bdwA-2eyyA:
undetectable
1bdwB-2eyyA:
undetectable
1bdwA-2eyyA:
4.41
1bdwB-2eyyA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fko 173AA LONG
HYPOTHETICAL
FERRIPYOCHELIN
BINDING PROTEIN


(Pyrococcus
horikoshii)
PF00132
(Hexapep)
3 VAL A  58
VAL A  78
TRP A  38
None
0.75A 1bdwA-2fkoA:
undetectable
1bdwB-2fkoA:
undetectable
1bdwA-2fkoA:
7.46
1bdwB-2fkoA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fwr DNA REPAIR PROTEIN
RAD25


(Archaeoglobus
fulgidus)
PF04851
(ResIII)
PF16203
(ERCC3_RAD25_C)
3 VAL A 246
VAL A 114
TRP A 105
None
0.92A 1bdwA-2fwrA:
undetectable
1bdwB-2fwrA:
undetectable
1bdwA-2fwrA:
3.40
1bdwB-2fwrA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hu9 MERCURIC TRANSPORT
PROTEIN PERIPLASMIC
COMPONENT


(Archaeoglobus
fulgidus)
no annotation 3 VAL A  14
VAL A 110
TRP A  12
None
0.93A 1bdwA-2hu9A:
undetectable
1bdwB-2hu9A:
undetectable
1bdwA-2hu9A:
9.82
1bdwB-2hu9A:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipi ACLACINOMYCIN
OXIDOREDUCTASE
(AKNOX)


(Streptomyces
galilaeus)
PF01565
(FAD_binding_4)
PF08031
(BBE)
3 VAL A 161
VAL A 175
TRP A 207
None
0.91A 1bdwA-2ipiA:
undetectable
1bdwB-2ipiA:
undetectable
1bdwA-2ipiA:
5.41
1bdwB-2ipiA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix5 ACYL-COENZYME A
OXIDASE 4,
PEROXISOMAL


(Arabidopsis
thaliana)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
3 VAL A 265
VAL A 263
TRP A 197
None
0.88A 1bdwA-2ix5A:
undetectable
1bdwB-2ix5A:
undetectable
1bdwA-2ix5A:
3.28
1bdwB-2ix5A:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf4 PERIPLASMIC
TREHALASE


(Escherichia
coli)
PF01204
(Trehalase)
3 VAL A 459
VAL A 411
TRP A 458
None
0.97A 1bdwA-2jf4A:
undetectable
1bdwB-2jf4A:
undetectable
1bdwA-2jf4A:
3.75
1bdwB-2jf4A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o4u DIMERIC DIHYDRODIOL
DEHYDROGENASE


(Macaca
fascicularis)
PF01408
(GFO_IDH_MocA)
3 VAL X1031
VAL X1034
TRP X1005
None
0.93A 1bdwA-2o4uX:
undetectable
1bdwB-2o4uX:
undetectable
1bdwA-2o4uX:
3.08
1bdwB-2o4uX:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oap TYPE II SECRETION
SYSTEM PROTEIN


(Archaeoglobus
fulgidus)
PF00437
(T2SSE)
3 VAL 1 291
VAL 1 339
TRP 1 306
None
0.89A 1bdwA-2oap1:
undetectable
1bdwB-2oap1:
undetectable
1bdwA-2oap1:
3.58
1bdwB-2oap1:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pan GLYOXYLATE
CARBOLIGASE


(Escherichia
coli)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
3 VAL A 232
VAL A 234
TRP A 348
None
0.99A 1bdwA-2panA:
undetectable
1bdwB-2panA:
undetectable
1bdwA-2panA:
7.35
1bdwB-2panA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcd UNCHARACTERIZED
PROTEIN


(Pectobacterium
atrosepticum)
PF11533
(DUF3225)
3 VAL A  89
VAL A  79
TRP A 109
None
0.68A 1bdwA-2rcdA:
undetectable
1bdwB-2rcdA:
undetectable
1bdwA-2rcdA:
8.93
1bdwB-2rcdA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x30 PHOSPHORIBOSYL
ISOMERASE A


(Streptomyces
coelicolor)
PF00977
(His_biosynth)
3 VAL A  10
VAL A  18
TRP A  41
None
0.83A 1bdwA-2x30A:
undetectable
1bdwB-2x30A:
undetectable
1bdwA-2x30A:
7.04
1bdwB-2x30A:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z36 CYTOCHROME P450 TYPE
COMPACTIN
3'',4''-HYDROXYLASE


(Nonomuraea
recticatena)
PF00067
(p450)
3 VAL A 317
VAL A 319
TRP A  49
None
0.99A 1bdwA-2z36A:
undetectable
1bdwB-2z36A:
undetectable
1bdwA-2z36A:
3.22
1bdwB-2z36A:
3.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a21 PUTATIVE SECRETED
ALPHA-GALACTOSIDASE


(Streptomyces
avermitilis)
PF00652
(Ricin_B_lectin)
PF16499
(Melibiase_2)
3 VAL A 423
VAL A 369
TRP A 401
None
0.75A 1bdwA-3a21A:
undetectable
1bdwB-3a21A:
undetectable
1bdwA-3a21A:
2.51
1bdwB-3a21A:
2.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqx BETA-1,3-GLUCAN-BIND
ING PROTEIN


(Bombyx mori)
PF15886
(CBM39)
3 VAL A  20
VAL A  18
TRP A  58
None
0.94A 1bdwA-3aqxA:
undetectable
1bdwB-3aqxA:
undetectable
1bdwA-3aqxA:
12.24
1bdwB-3aqxA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5h GLUCOCORTICOID
RECEPTOR DNA-BINDING
FACTOR 1


(Homo sapiens)
PF00071
(Ras)
3 VAL A  94
VAL A  19
TRP A  76
None
0.94A 1bdwA-3c5hA:
undetectable
1bdwB-3c5hA:
undetectable
1bdwA-3c5hA:
3.90
1bdwB-3c5hA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0e REPLICATION PROTEIN
A


(Methanococcus
maripaludis)
PF01336
(tRNA_anti-codon)
3 VAL A  86
VAL A  75
TRP A  55
None
0.99A 1bdwA-3e0eA:
undetectable
1bdwB-3e0eA:
undetectable
1bdwA-3e0eA:
14.04
1bdwB-3e0eA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3esh PROTEIN SIMILAR TO
METAL-DEPENDENT
HYDROLASE


(Staphylococcus
aureus)
PF00753
(Lactamase_B)
3 VAL A  27
VAL A 219
TRP A  32
None
0.74A 1bdwA-3eshA:
undetectable
1bdwB-3eshA:
undetectable
1bdwA-3eshA:
3.65
1bdwB-3eshA:
3.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3im0 VAL-1

(Paramecium
bursaria
Chlorella virus
CVK2)
no annotation 3 VAL A  79
VAL A  39
TRP A  77
None
0.85A 1bdwA-3im0A:
undetectable
1bdwB-3im0A:
undetectable
1bdwA-3im0A:
5.33
1bdwB-3im0A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lun ULILYSIN

(Methanosarcina
acetivorans)
PF05572
(Peptidase_M43)
3 VAL A  74
VAL A 145
TRP A  75
None
0.97A 1bdwA-3lunA:
undetectable
1bdwB-3lunA:
undetectable
1bdwA-3lunA:
5.65
1bdwB-3lunA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3md0 ARGININE/ORNITHINE
TRANSPORT SYSTEM
ATPASE


(Mycobacterium
tuberculosis)
PF03308
(ArgK)
3 VAL A 294
VAL A 290
TRP A 295
None
0.84A 1bdwA-3md0A:
undetectable
1bdwB-3md0A:
undetectable
1bdwA-3md0A:
6.67
1bdwB-3md0A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mj8 STIMULATORY HAMSTER
ANTIBODY HL4E10 FAB
LIGHT CHAIN


(Cricetulus
migratorius)
no annotation 3 VAL L  31
VAL L  33
TRP L  91
None
0.97A 1bdwA-3mj8L:
undetectable
1bdwB-3mj8L:
undetectable
1bdwA-3mj8L:
6.18
1bdwB-3mj8L:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyf D-ARGININE
DEHYDROGENASE


(Pseudomonas
aeruginosa)
PF01266
(DAO)
3 VAL A1194
VAL A1008
TRP A1181
None
0.70A 1bdwA-3nyfA:
undetectable
1bdwB-3nyfA:
undetectable
1bdwA-3nyfA:
3.46
1bdwB-3nyfA:
3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogj PRKG1 PROTEIN

(Homo sapiens)
PF00027
(cNMP_binding)
3 VAL A 157
VAL A 155
TRP A 205
None
0.66A 1bdwA-3ogjA:
undetectable
1bdwB-3ogjA:
undetectable
1bdwA-3ogjA:
12.33
1bdwB-3ogjA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz9 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE. GLYCOSYL
HYDROLASE FAMILY 5


(Thermotoga
petrophila)
PF00150
(Cellulase)
3 VAL A 230
VAL A 232
TRP A 193
None
0.73A 1bdwA-3pz9A:
undetectable
1bdwB-3pz9A:
undetectable
1bdwA-3pz9A:
3.37
1bdwB-3pz9A:
3.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r1w CARBONIC ANHYDRASE

(unidentified)
PF00132
(Hexapep)
3 VAL A  67
VAL A  94
TRP A  47
None
0.73A 1bdwA-3r1wA:
undetectable
1bdwB-3r1wA:
undetectable
1bdwA-3r1wA:
5.71
1bdwB-3r1wA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shr CGMP-DEPENDENT
PROTEIN KINASE 1


(Bos taurus)
PF00027
(cNMP_binding)
3 VAL A 141
VAL A 139
TRP A 189
None
0.67A 1bdwA-3shrA:
undetectable
1bdwB-3shrA:
undetectable
1bdwA-3shrA:
6.29
1bdwB-3shrA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq8 BETA-GLUCOSIDASE

(Pyrococcus
furiosus)
PF00232
(Glyco_hydro_1)
3 VAL A 259
VAL A 261
TRP A 202
None
0.97A 1bdwA-3wq8A:
undetectable
1bdwB-3wq8A:
undetectable
1bdwA-3wq8A:
7.34
1bdwB-3wq8A:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A


(Cellvibrio
japonicus)
PF02449
(Glyco_hydro_42)
3 VAL A 202
VAL A 206
TRP A 129
None
0.75A 1bdwA-4d1iA:
undetectable
1bdwB-4d1iA:
undetectable
1bdwA-4d1iA:
4.55
1bdwB-4d1iA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eex ALCOHOL
DEHYDROGENASE 1


(Lactococcus
lactis)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 VAL A 288
VAL A 262
TRP A  86
None
0.97A 1bdwA-4eexA:
undetectable
1bdwB-4eexA:
undetectable
1bdwA-4eexA:
3.42
1bdwB-4eexA:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f2g ORNITHINE
CARBAMOYLTRANSFERASE
1


(Burkholderia
thailandensis)
PF00185
(OTCace)
PF02729
(OTCace_N)
3 VAL A 160
VAL A 273
TRP A 245
None
0.97A 1bdwA-4f2gA:
undetectable
1bdwB-4f2gA:
undetectable
1bdwA-4f2gA:
8.00
1bdwB-4f2gA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdj N-ACETYLGALACTOSAMIN
E-6-SULFATASE


(Homo sapiens)
PF00884
(Sulfatase)
PF14707
(Sulfatase_C)
3 VAL A 138
VAL A 232
TRP A 159
None
0.81A 1bdwA-4fdjA:
undetectable
1bdwB-4fdjA:
undetectable
1bdwA-4fdjA:
2.94
1bdwB-4fdjA:
2.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2r ACCD6,
CARBOXYLTRANSFERASE
BETA-SUBUNIT OF
ACYL-COA CARBOXYLASE


(Mycobacterium
tuberculosis)
PF01039
(Carboxyl_trans)
3 VAL A 130
VAL A 148
TRP A  94
None
0.78A 1bdwA-4g2rA:
undetectable
1bdwB-4g2rA:
undetectable
1bdwA-4g2rA:
3.67
1bdwB-4g2rA:
3.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gi2 CROTONYL-COA
CARBOXYLASE/REDUCTAS
E


(Methylobacterium
extorquens)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 VAL A  81
VAL A  76
TRP A  82
None
0.82A 1bdwA-4gi2A:
undetectable
1bdwB-4gi2A:
undetectable
1bdwA-4gi2A:
5.09
1bdwB-4gi2A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkv ALCOHOL
DEHYDROGENASE,
PROPANOL-PREFERRING


(Escherichia
coli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 VAL A 284
VAL A 258
TRP A  84
NAD  A 401 (-3.6A)
NAD  A 401 (-3.9A)
None
0.99A 1bdwA-4gkvA:
undetectable
1bdwB-4gkvA:
undetectable
1bdwA-4gkvA:
5.24
1bdwB-4gkvA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hc6 HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE


(Mycobacterium
tuberculosis)
PF01648
(ACPS)
3 VAL A   4
VAL A   6
TRP A  64
None
0.98A 1bdwA-4hc6A:
undetectable
1bdwB-4hc6A:
undetectable
1bdwA-4hc6A:
8.73
1bdwB-4hc6A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN


(Acidovorax
citrulli)
PF00544
(Pec_lyase_C)
3 VAL A 338
VAL A 251
TRP A  40
None
0.98A 1bdwA-4hwvA:
undetectable
1bdwB-4hwvA:
undetectable
1bdwA-4hwvA:
3.08
1bdwB-4hwvA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ihq FLAI ATPASE

(Sulfolobus
acidocaldarius)
PF00437
(T2SSE)
3 VAL A 286
VAL A 334
TRP A 301
None
0.78A 1bdwA-4ihqA:
undetectable
1bdwB-4ihqA:
undetectable
1bdwA-4ihqA:
7.50
1bdwB-4ihqA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkm BETA-GLUCURONIDASE

(Clostridium
perfringens)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
3 VAL A 441
VAL A 443
TRP A 407
None
0.87A 1bdwA-4jkmA:
undetectable
1bdwB-4jkmA:
undetectable
1bdwA-4jkmA:
4.10
1bdwB-4jkmA:
4.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kmr TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY


(Sanguibacter
keddieii)
PF13377
(Peripla_BP_3)
3 VAL A 227
VAL A 225
TRP A 230
None
0.84A 1bdwA-4kmrA:
undetectable
1bdwB-4kmrA:
undetectable
1bdwA-4kmrA:
6.19
1bdwB-4kmrA:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN


(Caulobacter
vibrioides)
PF04390
(LptE)
3 VAL A 100
VAL A 120
TRP A 102
None
0.98A 1bdwA-4kwyA:
undetectable
1bdwB-4kwyA:
undetectable
1bdwA-4kwyA:
8.09
1bdwB-4kwyA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx6 TRAP-TYPE
C4-DICARBOXYLATE:H+
SYMPORT SYSTEM
SUBSTRATE-BINDING
COMPONENT DCTP


(Shewanella
oneidensis)
PF03480
(DctP)
3 VAL A 318
VAL A 314
TRP A 319
None
0.85A 1bdwA-4mx6A:
undetectable
1bdwB-4mx6A:
undetectable
1bdwA-4mx6A:
3.85
1bdwB-4mx6A:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9n STEROL UPTAKE
CONTROL PROTEIN 2,
LYSOZYME


(Saccharomyces
cerevisiae;
Escherichia
virus T4)
PF00959
(Phage_lysozyme)
PF11951
(Fungal_trans_2)
3 VAL A 866
VAL A 875
TRP A 867
None
0.96A 1bdwA-4n9nA:
undetectable
1bdwB-4n9nA:
undetectable
1bdwA-4n9nA:
3.16
1bdwB-4n9nA:
3.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qp0 ENDO-BETA-MANNANASE

(Rhizomucor
miehei)
PF00150
(Cellulase)
3 VAL A 215
VAL A 217
TRP A 170
None
0.68A 1bdwA-4qp0A:
undetectable
1bdwB-4qp0A:
undetectable
1bdwA-4qp0A:
5.02
1bdwB-4qp0A:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u28 PHOSPHORIBOSYL
ISOMERASE A


(Streptomyces
sviceus)
PF00977
(His_biosynth)
3 VAL A  14
VAL A  22
TRP A  45
None
0.93A 1bdwA-4u28A:
undetectable
1bdwB-4u28A:
undetectable
1bdwA-4u28A:
6.90
1bdwB-4u28A:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6z ALCOHOL
DEHYDROGENASE 1


(Saccharomyces
cerevisiae)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 VAL A 295
VAL A 268
TRP A  92
8ID  A 403 (-3.5A)
8ID  A 403 (-3.9A)
ETF  A 404 (-3.3A)
0.98A 1bdwA-4w6zA:
undetectable
1bdwB-4w6zA:
undetectable
1bdwA-4w6zA:
6.06
1bdwB-4w6zA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd1 ACETOACETATE-COA
LIGASE


(Streptomyces
lividans)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N)
3 VAL A  59
VAL A  65
TRP A  62
None
EDO  A 715 (-3.8A)
None
0.87A 1bdwA-4wd1A:
undetectable
1bdwB-4wd1A:
undetectable
1bdwA-4wd1A:
4.07
1bdwB-4wd1A:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x2r 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)METHYLIDENEAM
INO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE


(Actinomyces
urogenitalis)
PF00977
(His_biosynth)
3 VAL A   8
VAL A  16
TRP A  39
None
0.98A 1bdwA-4x2rA:
undetectable
1bdwB-4x2rA:
undetectable
1bdwA-4x2rA:
15.00
1bdwB-4x2rA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6d T-CELL SURFACE
GLYCOPROTEIN CD1A


(Homo sapiens)
PF07654
(C1-set)
PF16497
(MHC_I_3)
3 VAL A  12
VAL A  98
TRP A  31
None
0.61A 1bdwA-4x6dA:
undetectable
1bdwB-4x6dA:
undetectable
1bdwA-4x6dA:
3.75
1bdwB-4x6dA:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9s PHOSPHORIBOSYL
ISOMERASE A


(Streptomyces
sp. Mg1)
PF00977
(His_biosynth)
3 VAL A  12
VAL A  20
TRP A  43
None
0.91A 1bdwA-4x9sA:
undetectable
1bdwB-4x9sA:
undetectable
1bdwA-4x9sA:
7.48
1bdwB-4x9sA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeq TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT


(Desulfovibrio
vulgaris)
PF03480
(DctP)
3 VAL A  45
VAL A 101
TRP A 204
None
None
PAF  A 401 (-3.7A)
0.83A 1bdwA-4xeqA:
undetectable
1bdwB-4xeqA:
undetectable
1bdwA-4xeqA:
5.49
1bdwB-4xeqA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xxw PROTOCADHERIN-15

(Mus musculus)
no annotation 3 VAL B  60
VAL B  94
TRP B  63
None
0.95A 1bdwA-4xxwB:
undetectable
1bdwB-4xxwB:
undetectable
1bdwA-4xxwB:
8.16
1bdwB-4xxwB:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE


(Aspergillus
flavus)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
3 VAL A 107
VAL A 103
TRP A 108
None
0.86A 1bdwA-4ynuA:
undetectable
1bdwB-4ynuA:
undetectable
1bdwA-4ynuA:
2.96
1bdwB-4ynuA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z07 CGMP-DEPENDENT
PROTEIN KINASE 1


(Homo sapiens)
PF00027
(cNMP_binding)
3 VAL A 157
VAL A 155
TRP A 205
None
0.66A 1bdwA-4z07A:
undetectable
1bdwB-4z07A:
undetectable
1bdwA-4z07A:
5.19
1bdwB-4z07A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5q CYTOCHROME P450
HYDROXYLASE


(Streptomyces
atroolivaceus)
PF00067
(p450)
3 VAL A 313
VAL A 315
TRP A  50
None
0.99A 1bdwA-4z5qA:
undetectable
1bdwB-4z5qA:
undetectable
1bdwA-4z5qA:
5.31
1bdwB-4z5qA:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5an9 60S RIBOSOMAL
PROTEIN L3


(Dictyostelium
discoideum)
PF00297
(Ribosomal_L3)
3 VAL A  87
VAL A 163
TRP A 106
None
0.92A 1bdwA-5an9A:
undetectable
1bdwB-5an9A:
undetectable
1bdwA-5an9A:
5.06
1bdwB-5an9A:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF14492
(EFG_II)
3 VAL K 232
VAL K 144
TRP K 268
None
0.93A 1bdwA-5anbK:
undetectable
1bdwB-5anbK:
undetectable
1bdwA-5anbK:
1.54
1bdwB-5anbK:
1.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT


(Candidatus
Kuenenia
stuttgartiensis)
no annotation 3 VAL A 746
VAL A 735
TRP A 747
None
0.53A 1bdwA-5c2vA:
undetectable
1bdwB-5c2vA:
undetectable
1bdwA-5c2vA:
2.33
1bdwB-5c2vA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9j T-CELL SURFACE
GLYCOPROTEIN
CD1C,T-CELL SURFACE
GLYCOPROTEIN CD1B


(Homo sapiens)
PF07654
(C1-set)
PF16497
(MHC_I_3)
3 VAL A  15
VAL A 101
TRP A  34
STE  A 303 ( 4.7A)
None
PO4  A 308 (-3.2A)
0.70A 1bdwA-5c9jA:
undetectable
1bdwB-5c9jA:
undetectable
1bdwA-5c9jA:
4.62
1bdwB-5c9jA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9l PLL LECTIN

(Photorhabdus
luminescens)
PF03984
(DUF346)
3 VAL A  91
VAL A  89
TRP A  99
None
None
EDO  A 413 (-3.6A)
0.95A 1bdwA-5c9lA:
undetectable
1bdwB-5c9lA:
undetectable
1bdwA-5c9lA:
4.52
1bdwB-5c9lA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehk LANTIBIOTIC
DEHYDRATASE


(Microbispora
corallina)
PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C)
3 VAL A 976
VAL A 973
TRP A 984
None
0.61A 1bdwA-5ehkA:
undetectable
1bdwB-5ehkA:
undetectable
1bdwA-5ehkA:
5.22
1bdwB-5ehkA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw7 GLUCOSIDASE YGJK

(Escherichia
coli)
PF01204
(Trehalase)
3 VAL A 686
VAL A 684
TRP A 744
None
0.89A 1bdwA-5gw7A:
undetectable
1bdwB-5gw7A:
undetectable
1bdwA-5gw7A:
1.76
1bdwB-5gw7A:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hl6 PUTATIVE GAF SENSOR
PROTEIN


(Burkholderia
vietnamiensis)
PF13185
(GAF_2)
3 VAL A 119
VAL A  96
TRP A 132
None
0.84A 1bdwA-5hl6A:
undetectable
1bdwB-5hl6A:
undetectable
1bdwA-5hl6A:
13.27
1bdwB-5hl6A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6z SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER


(Homo sapiens)
PF00209
(SNF)
3 VAL A 102
VAL A  97
TRP A 103
None
0.75A 1bdwA-5i6zA:
undetectable
1bdwB-5i6zA:
undetectable
1bdwA-5i6zA:
2.87
1bdwB-5i6zA:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihx TYROSINE--TRNA
LIGASE,
MITOCHONDRIAL


(Aspergillus
nidulans)
PF00579
(tRNA-synt_1b)
3 VAL A 153
VAL A 158
TRP A 154
None
0.92A 1bdwA-5ihxA:
undetectable
1bdwB-5ihxA:
undetectable
1bdwA-5ihxA:
4.60
1bdwB-5ihxA:
4.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F


(Escherichia
coli)
PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C)
3 VAL A 753
VAL A 755
TRP A 652
75C  A1301 (-4.7A)
None
None
0.98A 1bdwA-5ja1A:
undetectable
1bdwB-5ja1A:
undetectable
1bdwA-5ja1A:
2.26
1bdwB-5ja1A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jx5 GLUCANASE

(Orpinomyces sp.
Y102)
PF01341
(Glyco_hydro_6)
3 VAL A 400
VAL A 327
TRP A 401
None
NH4  A 516 (-3.6A)
None
0.96A 1bdwA-5jx5A:
undetectable
1bdwB-5jx5A:
undetectable
1bdwA-5jx5A:
5.47
1bdwB-5jx5A:
5.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxv SCAFFOLDIN C

(Ruminococcus
flavefaciens)
PF00963
(Cohesin)
3 VAL A  55
VAL A 107
TRP A  91
None
0.91A 1bdwA-5lxvA:
undetectable
1bdwB-5lxvA:
undetectable
1bdwA-5lxvA:
8.74
1bdwB-5lxvA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m2d ENDOGLUCANASE-LIKE
PROTEIN


(Acremonium
chrysogenum)
no annotation 3 VAL A  53
VAL A 218
TRP A  55
None
0.89A 1bdwA-5m2dA:
undetectable
1bdwB-5m2dA:
undetectable
1bdwA-5m2dA:
6.83
1bdwB-5m2dA:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mus L PROTEIN

(California
reptarenavirus)
no annotation 3 VAL A2013
VAL A2004
TRP A2030
None
0.95A 1bdwA-5musA:
undetectable
1bdwB-5musA:
undetectable
1bdwA-5musA:
3.40
1bdwB-5musA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oee LARGE SUBUNIT
TERMINASE


(Phage D6E)
no annotation 3 VAL A 260
VAL A 325
TRP A 275
None
0.81A 1bdwA-5oeeA:
undetectable
1bdwB-5oeeA:
undetectable
1bdwA-5oeeA:
3.94
1bdwB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT FWDD


(Methanothermobacter
wolfeii)
PF01568
(Molydop_binding)
3 VAL D  60
VAL D  51
TRP D  83
None
0.99A 1bdwA-5t5iD:
undetectable
1bdwB-5t5iD:
undetectable
1bdwA-5t5iD:
10.42
1bdwB-5t5iD:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tnu DNA-DEPENDENT ATPASE
XPBII


(Sulfurisphaera
tokodaii)
no annotation 3 VAL A 221
VAL A  89
TRP A  80
None
0.97A 1bdwA-5tnuA:
undetectable
1bdwB-5tnuA:
undetectable
1bdwA-5tnuA:
3.45
1bdwB-5tnuA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7


(Homo sapiens)
PF01663
(Phosphodiest)
3 VAL A 191
VAL A  36
TRP A 127
None
0.94A 1bdwA-5udyA:
undetectable
1bdwB-5udyA:
undetectable
1bdwA-5udyA:
5.17
1bdwB-5udyA:
5.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uk5 NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1


(Rattus
norvegicus)
PF00008
(EGF)
PF07645
(EGF_CA)
3 VAL A 324
VAL A 322
TRP A 327
FUC  A 604 ( 4.9A)
FUC  A 604 (-4.4A)
None
0.70A 1bdwA-5uk5A:
undetectable
1bdwB-5uk5A:
undetectable
1bdwA-5uk5A:
3.47
1bdwB-5uk5A:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbu CYTOCHROME P450
21-HYDROXYLASE


(Homo sapiens)
PF00067
(p450)
3 VAL A 359
VAL A 470
TRP A 303
HEM  A 501 (-4.7A)
None
None
0.98A 1bdwA-5vbuA:
undetectable
1bdwB-5vbuA:
undetectable
1bdwA-5vbuA:
6.52
1bdwB-5vbuA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vms POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY
KQT MEMBER 1


(Xenopus laevis)
PF00520
(Ion_trans)
PF03520
(KCNQ_channel)
3 VAL A 177
VAL A 175
TRP A 178
None
0.97A 1bdwA-5vmsA:
undetectable
1bdwB-5vmsA:
undetectable
1bdwA-5vmsA:
5.58
1bdwB-5vmsA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wug BETA-GLUCOSIDASE

(Paenibacillus
barengoltzii)
no annotation 3 VAL A 315
VAL A 382
TRP A 313
None
0.97A 1bdwA-5wugA:
undetectable
1bdwB-5wugA:
undetectable
1bdwA-5wugA:
undetectable
1bdwB-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MEMBRANE-BOUND
HYDROGENASE SUBUNIT
ALPHA


(Pyrococcus
furiosus)
no annotation 3 VAL L 327
VAL L 337
TRP L 339
None
0.68A 1bdwA-6cfwL:
undetectable
1bdwB-6cfwL:
undetectable
1bdwA-6cfwL:
undetectable
1bdwB-6cfwL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cv7 -

(-)
no annotation 3 VAL A  60
VAL A  94
TRP A  63
EDO  A 407 (-4.2A)
None
None
0.95A 1bdwA-6cv7A:
undetectable
1bdwB-6cv7A:
undetectable
1bdwA-6cv7A:
undetectable
1bdwB-6cv7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu6 AMMONIUM TRANSPORTER

(Candidatus
Kuenenia
stuttgartiensis)
no annotation 3 VAL A 231
VAL A 233
TRP A  12
None
0.96A 1bdwA-6eu6A:
undetectable
1bdwB-6eu6A:
undetectable
1bdwA-6eu6A:
undetectable
1bdwB-6eu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33


(Homo sapiens)
no annotation 3 VAL B 135
VAL B 124
TRP B 146
None
0.90A 1bdwA-6f9nB:
undetectable
1bdwB-6f9nB:
undetectable
1bdwA-6f9nB:
undetectable
1bdwB-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fvs CYS-LOOP
LIGAND-GATED ION
CHANNEL


(endosymbiont of
Tevnia
jerichonana)
no annotation 3 VAL A 275
VAL A 270
TRP A 276
None
0.95A 1bdwA-6fvsA:
undetectable
1bdwB-6fvsA:
undetectable
1bdwA-6fvsA:
undetectable
1bdwB-6fvsA:
undetectable