SIMILAR PATTERNS OF AMINO ACIDS FOR 1BDW_B_DVAB8_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ii2 | PHOSPHOENOLPYRUVATECARBOXYKINASE (Trypanosomacruzi) |
PF01293(PEPCK_ATP) | 3 | VAL A 330VAL A 216TRP A 411 | None | 0.91A | 1bdwA-1ii2A:undetectable1bdwB-1ii2A:undetectable | 1bdwA-1ii2A:3.381bdwB-1ii2A:3.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmz | AMINE DEHYDROGENASE (Pseudomonasputida) |
PF09098(Dehyd-heme_bind)PF09099(Qn_am_d_aIII)PF09100(Qn_am_d_aIV)PF14930(Qn_am_d_aII) | 3 | VAL A 368VAL A 370TRP A 398 | None | 0.98A | 1bdwA-1jmzA:undetectable1bdwB-1jmzA:undetectable | 1bdwA-1jmzA:2.231bdwB-1jmzA:2.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7s | FERRICHROME-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF01497(Peripla_BP_2) | 3 | VAL N 46VAL N 101TRP N 43 | None | 0.96A | 1bdwA-1k7sN:undetectable1bdwB-1k7sN:undetectable | 1bdwA-1k7sN:5.051bdwB-1k7sN:5.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kb0 | QUINOHEMOPROTEINALCOHOLDEHYDROGENASE (Comamonastestosteroni) |
PF13360(PQQ_2)PF13442(Cytochrome_CBB3) | 3 | VAL A 74VAL A 76TRP A 29 | None | 0.93A | 1bdwA-1kb0A:undetectable1bdwB-1kb0A:undetectable | 1bdwA-1kb0A:2.731bdwB-1kb0A:2.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqq | ALPHA-D-GLUCURONIDASE (Geobacillusstearothermophilus) |
PF03648(Glyco_hydro_67N)PF07477(Glyco_hydro_67C)PF07488(Glyco_hydro_67M) | 3 | VAL A 60VAL A 57TRP A 68 | NoneNoneGOL A 756 (-3.8A) | 0.99A | 1bdwA-1mqqA:undetectable1bdwB-1mqqA:undetectable | 1bdwA-1mqqA:3.461bdwB-1mqqA:3.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o7d | LYSOSOMALALPHA-MANNOSIDASE (Bos taurus) |
PF01074(Glyco_hydro_38) | 3 | VAL A 156VAL A 119TRP A 155 | None | 0.92A | 1bdwA-1o7dA:undetectable1bdwB-1o7dA:undetectable | 1bdwA-1o7dA:4.711bdwB-1o7dA:4.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p22 | F-BOX/WD-REPEATPROTEIN 1A (Homo sapiens) |
PF00400(WD40)PF12937(F-box-like) | 3 | VAL A 404VAL A 395TRP A 415 | None | 0.84A | 1bdwA-1p22A:undetectable1bdwB-1p22A:undetectable | 1bdwA-1p22A:2.921bdwB-1p22A:2.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1te2 | 2-DEOXYGLUCOSE-6-PPHOSPHATASE (Escherichiacoli) |
PF13419(HAD_2) | 3 | VAL A 57VAL A 76TRP A 61 | None | 0.94A | 1bdwA-1te2A:undetectable1bdwB-1te2A:undetectable | 1bdwA-1te2A:8.771bdwB-1te2A:8.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 3 | VAL A 369VAL A 364TRP A 135 | None | 0.89A | 1bdwA-1u7gA:undetectable1bdwB-1u7gA:undetectable | 1bdwA-1u7gA:5.191bdwB-1u7gA:5.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xhd | PUTATIVEACETYLTRANSFERASE/ACYLTRANSFERASE (Bacillus cereus) |
PF00132(Hexapep) | 3 | VAL A 57VAL A 77TRP A 37 | None | 0.86A | 1bdwA-1xhdA:undetectable1bdwB-1xhdA:undetectable | 1bdwA-1xhdA:9.781bdwB-1xhdA:9.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y96 | GEM-ASSOCIATEDPROTEIN 6 (Homo sapiens) |
PF06372(Gemin6) | 3 | VAL A 47VAL A 45TRP A 33 | None | 0.83A | 1bdwA-1y96A:undetectable1bdwB-1y96A:undetectable | 1bdwA-1y96A:12.311bdwB-1y96A:12.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z47 | PUTATIVEABC-TRANSPORTERATP-BINDING PROTEIN (Alicyclobacillusacidocaldarius) |
PF00005(ABC_tran)PF08402(TOBE_2) | 3 | VAL A 282VAL A 280TRP A 252 | None | 0.82A | 1bdwA-1z47A:undetectable1bdwB-1z47A:undetectable | 1bdwA-1z47A:2.961bdwB-1z47A:2.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zag | PROTEIN(ZINC-ALPHA-2-GLYCOPROTEIN) (Homo sapiens) |
PF00129(MHC_I)PF07654(C1-set) | 3 | VAL A 247VAL A 191TRP A 245 | None | 0.96A | 1bdwA-1zagA:undetectable1bdwB-1zagA:undetectable | 1bdwA-1zagA:4.381bdwB-1zagA:4.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c0h | MANNANENDO-1,4-BETA-MANNOSIDASE (Mytilus edulis) |
PF00150(Cellulase) | 3 | VAL A 235VAL A 237TRP A 172 | None | 0.77A | 1bdwA-2c0hA:undetectable1bdwB-2c0hA:undetectable | 1bdwA-2c0hA:7.641bdwB-2c0hA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1d | SOXA (Paracoccusdenitrificans) |
no annotation | 3 | VAL A 288VAL A 286TRP A 65 | None | 0.96A | 1bdwA-2c1dA:undetectable1bdwB-2c1dA:undetectable | 1bdwA-2c1dA:3.821bdwB-2c1dA:3.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ckb | ALPHA, BETA T CELLRECEPTOR (Mus musculus) |
PF07686(V-set)PF09291(DUF1968) | 3 | VAL A 114VAL A 112TRP A 82 | None | 0.75A | 1bdwA-2ckbA:undetectable1bdwB-2ckbA:undetectable | 1bdwA-2ckbA:6.291bdwB-2ckbA:6.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dvj | V-CRK SARCOMA VIRUSCT10 ONCOGENEHOMOLOG, ISOFORM A (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 3 | VAL A 37VAL A 51TRP A 15 | None | 0.84A | 1bdwA-2dvjA:undetectable1bdwB-2dvjA:undetectable | 1bdwA-2dvjA:7.611bdwB-2dvjA:7.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eyy | V-CRK SARCOMA VIRUSCT10 ONCOGENEHOMOLOG ISOFORM A (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 3 | VAL A 37VAL A 51TRP A 15 | None | 0.95A | 1bdwA-2eyyA:undetectable1bdwB-2eyyA:undetectable | 1bdwA-2eyyA:4.411bdwB-2eyyA:4.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fko | 173AA LONGHYPOTHETICALFERRIPYOCHELINBINDING PROTEIN (Pyrococcushorikoshii) |
PF00132(Hexapep) | 3 | VAL A 58VAL A 78TRP A 38 | None | 0.75A | 1bdwA-2fkoA:undetectable1bdwB-2fkoA:undetectable | 1bdwA-2fkoA:7.461bdwB-2fkoA:7.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fwr | DNA REPAIR PROTEINRAD25 (Archaeoglobusfulgidus) |
PF04851(ResIII)PF16203(ERCC3_RAD25_C) | 3 | VAL A 246VAL A 114TRP A 105 | None | 0.92A | 1bdwA-2fwrA:undetectable1bdwB-2fwrA:undetectable | 1bdwA-2fwrA:3.401bdwB-2fwrA:3.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hu9 | MERCURIC TRANSPORTPROTEIN PERIPLASMICCOMPONENT (Archaeoglobusfulgidus) |
no annotation | 3 | VAL A 14VAL A 110TRP A 12 | None | 0.93A | 1bdwA-2hu9A:undetectable1bdwB-2hu9A:undetectable | 1bdwA-2hu9A:9.821bdwB-2hu9A:9.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipi | ACLACINOMYCINOXIDOREDUCTASE(AKNOX) (Streptomycesgalilaeus) |
PF01565(FAD_binding_4)PF08031(BBE) | 3 | VAL A 161VAL A 175TRP A 207 | None | 0.91A | 1bdwA-2ipiA:undetectable1bdwB-2ipiA:undetectable | 1bdwA-2ipiA:5.411bdwB-2ipiA:5.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ix5 | ACYL-COENZYME AOXIDASE 4,PEROXISOMAL (Arabidopsisthaliana) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | VAL A 265VAL A 263TRP A 197 | None | 0.88A | 1bdwA-2ix5A:undetectable1bdwB-2ix5A:undetectable | 1bdwA-2ix5A:3.281bdwB-2ix5A:3.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jf4 | PERIPLASMICTREHALASE (Escherichiacoli) |
PF01204(Trehalase) | 3 | VAL A 459VAL A 411TRP A 458 | None | 0.97A | 1bdwA-2jf4A:undetectable1bdwB-2jf4A:undetectable | 1bdwA-2jf4A:3.751bdwB-2jf4A:3.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o4u | DIMERIC DIHYDRODIOLDEHYDROGENASE (Macacafascicularis) |
PF01408(GFO_IDH_MocA) | 3 | VAL X1031VAL X1034TRP X1005 | None | 0.93A | 1bdwA-2o4uX:undetectable1bdwB-2o4uX:undetectable | 1bdwA-2o4uX:3.081bdwB-2o4uX:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oap | TYPE II SECRETIONSYSTEM PROTEIN (Archaeoglobusfulgidus) |
PF00437(T2SSE) | 3 | VAL 1 291VAL 1 339TRP 1 306 | None | 0.89A | 1bdwA-2oap1:undetectable1bdwB-2oap1:undetectable | 1bdwA-2oap1:3.581bdwB-2oap1:3.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pan | GLYOXYLATECARBOLIGASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 3 | VAL A 232VAL A 234TRP A 348 | None | 0.99A | 1bdwA-2panA:undetectable1bdwB-2panA:undetectable | 1bdwA-2panA:7.351bdwB-2panA:7.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rcd | UNCHARACTERIZEDPROTEIN (Pectobacteriumatrosepticum) |
PF11533(DUF3225) | 3 | VAL A 89VAL A 79TRP A 109 | None | 0.68A | 1bdwA-2rcdA:undetectable1bdwB-2rcdA:undetectable | 1bdwA-2rcdA:8.931bdwB-2rcdA:8.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x30 | PHOSPHORIBOSYLISOMERASE A (Streptomycescoelicolor) |
PF00977(His_biosynth) | 3 | VAL A 10VAL A 18TRP A 41 | None | 0.83A | 1bdwA-2x30A:undetectable1bdwB-2x30A:undetectable | 1bdwA-2x30A:7.041bdwB-2x30A:7.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z36 | CYTOCHROME P450 TYPECOMPACTIN3'',4''-HYDROXYLASE (Nonomuraearecticatena) |
PF00067(p450) | 3 | VAL A 317VAL A 319TRP A 49 | None | 0.99A | 1bdwA-2z36A:undetectable1bdwB-2z36A:undetectable | 1bdwA-2z36A:3.221bdwB-2z36A:3.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a21 | PUTATIVE SECRETEDALPHA-GALACTOSIDASE (Streptomycesavermitilis) |
PF00652(Ricin_B_lectin)PF16499(Melibiase_2) | 3 | VAL A 423VAL A 369TRP A 401 | None | 0.75A | 1bdwA-3a21A:undetectable1bdwB-3a21A:undetectable | 1bdwA-3a21A:2.511bdwB-3a21A:2.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqx | BETA-1,3-GLUCAN-BINDING PROTEIN (Bombyx mori) |
PF15886(CBM39) | 3 | VAL A 20VAL A 18TRP A 58 | None | 0.94A | 1bdwA-3aqxA:undetectable1bdwB-3aqxA:undetectable | 1bdwA-3aqxA:12.241bdwB-3aqxA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c5h | GLUCOCORTICOIDRECEPTOR DNA-BINDINGFACTOR 1 (Homo sapiens) |
PF00071(Ras) | 3 | VAL A 94VAL A 19TRP A 76 | None | 0.94A | 1bdwA-3c5hA:undetectable1bdwB-3c5hA:undetectable | 1bdwA-3c5hA:3.901bdwB-3c5hA:3.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0e | REPLICATION PROTEINA (Methanococcusmaripaludis) |
PF01336(tRNA_anti-codon) | 3 | VAL A 86VAL A 75TRP A 55 | None | 0.99A | 1bdwA-3e0eA:undetectable1bdwB-3e0eA:undetectable | 1bdwA-3e0eA:14.041bdwB-3e0eA:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3esh | PROTEIN SIMILAR TOMETAL-DEPENDENTHYDROLASE (Staphylococcusaureus) |
PF00753(Lactamase_B) | 3 | VAL A 27VAL A 219TRP A 32 | None | 0.74A | 1bdwA-3eshA:undetectable1bdwB-3eshA:undetectable | 1bdwA-3eshA:3.651bdwB-3eshA:3.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3im0 | VAL-1 (ParameciumbursariaChlorella virusCVK2) |
no annotation | 3 | VAL A 79VAL A 39TRP A 77 | None | 0.85A | 1bdwA-3im0A:undetectable1bdwB-3im0A:undetectable | 1bdwA-3im0A:5.331bdwB-3im0A:5.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lun | ULILYSIN (Methanosarcinaacetivorans) |
PF05572(Peptidase_M43) | 3 | VAL A 74VAL A 145TRP A 75 | None | 0.97A | 1bdwA-3lunA:undetectable1bdwB-3lunA:undetectable | 1bdwA-3lunA:5.651bdwB-3lunA:5.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3md0 | ARGININE/ORNITHINETRANSPORT SYSTEMATPASE (Mycobacteriumtuberculosis) |
PF03308(ArgK) | 3 | VAL A 294VAL A 290TRP A 295 | None | 0.84A | 1bdwA-3md0A:undetectable1bdwB-3md0A:undetectable | 1bdwA-3md0A:6.671bdwB-3md0A:6.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mj8 | STIMULATORY HAMSTERANTIBODY HL4E10 FABLIGHT CHAIN (Cricetulusmigratorius) |
no annotation | 3 | VAL L 31VAL L 33TRP L 91 | None | 0.97A | 1bdwA-3mj8L:undetectable1bdwB-3mj8L:undetectable | 1bdwA-3mj8L:6.181bdwB-3mj8L:6.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyf | D-ARGININEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF01266(DAO) | 3 | VAL A1194VAL A1008TRP A1181 | None | 0.70A | 1bdwA-3nyfA:undetectable1bdwB-3nyfA:undetectable | 1bdwA-3nyfA:3.461bdwB-3nyfA:3.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogj | PRKG1 PROTEIN (Homo sapiens) |
PF00027(cNMP_binding) | 3 | VAL A 157VAL A 155TRP A 205 | None | 0.66A | 1bdwA-3ogjA:undetectable1bdwB-3ogjA:undetectable | 1bdwA-3ogjA:12.331bdwB-3ogjA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pz9 | MANNANENDO-1,4-BETA-MANNOSIDASE. GLYCOSYLHYDROLASE FAMILY 5 (Thermotogapetrophila) |
PF00150(Cellulase) | 3 | VAL A 230VAL A 232TRP A 193 | None | 0.73A | 1bdwA-3pz9A:undetectable1bdwB-3pz9A:undetectable | 1bdwA-3pz9A:3.371bdwB-3pz9A:3.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r1w | CARBONIC ANHYDRASE (unidentified) |
PF00132(Hexapep) | 3 | VAL A 67VAL A 94TRP A 47 | None | 0.73A | 1bdwA-3r1wA:undetectable1bdwB-3r1wA:undetectable | 1bdwA-3r1wA:5.711bdwB-3r1wA:5.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3shr | CGMP-DEPENDENTPROTEIN KINASE 1 (Bos taurus) |
PF00027(cNMP_binding) | 3 | VAL A 141VAL A 139TRP A 189 | None | 0.67A | 1bdwA-3shrA:undetectable1bdwB-3shrA:undetectable | 1bdwA-3shrA:6.291bdwB-3shrA:6.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wq8 | BETA-GLUCOSIDASE (Pyrococcusfuriosus) |
PF00232(Glyco_hydro_1) | 3 | VAL A 259VAL A 261TRP A 202 | None | 0.97A | 1bdwA-3wq8A:undetectable1bdwB-3wq8A:undetectable | 1bdwA-3wq8A:7.341bdwB-3wq8A:7.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d1i | BETA-GALACTOSIDASE,PUTATIVE, BGL35A (Cellvibriojaponicus) |
PF02449(Glyco_hydro_42) | 3 | VAL A 202VAL A 206TRP A 129 | None | 0.75A | 1bdwA-4d1iA:undetectable1bdwB-4d1iA:undetectable | 1bdwA-4d1iA:4.551bdwB-4d1iA:4.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eex | ALCOHOLDEHYDROGENASE 1 (Lactococcuslactis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | VAL A 288VAL A 262TRP A 86 | None | 0.97A | 1bdwA-4eexA:undetectable1bdwB-4eexA:undetectable | 1bdwA-4eexA:3.421bdwB-4eexA:3.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f2g | ORNITHINECARBAMOYLTRANSFERASE1 (Burkholderiathailandensis) |
PF00185(OTCace)PF02729(OTCace_N) | 3 | VAL A 160VAL A 273TRP A 245 | None | 0.97A | 1bdwA-4f2gA:undetectable1bdwB-4f2gA:undetectable | 1bdwA-4f2gA:8.001bdwB-4f2gA:8.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdj | N-ACETYLGALACTOSAMINE-6-SULFATASE (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 3 | VAL A 138VAL A 232TRP A 159 | None | 0.81A | 1bdwA-4fdjA:undetectable1bdwB-4fdjA:undetectable | 1bdwA-4fdjA:2.941bdwB-4fdjA:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2r | ACCD6,CARBOXYLTRANSFERASEBETA-SUBUNIT OFACYL-COA CARBOXYLASE (Mycobacteriumtuberculosis) |
PF01039(Carboxyl_trans) | 3 | VAL A 130VAL A 148TRP A 94 | None | 0.78A | 1bdwA-4g2rA:undetectable1bdwB-4g2rA:undetectable | 1bdwA-4g2rA:3.671bdwB-4g2rA:3.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gi2 | CROTONYL-COACARBOXYLASE/REDUCTASE (Methylobacteriumextorquens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | VAL A 81VAL A 76TRP A 82 | None | 0.82A | 1bdwA-4gi2A:undetectable1bdwB-4gi2A:undetectable | 1bdwA-4gi2A:5.091bdwB-4gi2A:5.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkv | ALCOHOLDEHYDROGENASE,PROPANOL-PREFERRING (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | VAL A 284VAL A 258TRP A 84 | NAD A 401 (-3.6A)NAD A 401 (-3.9A)None | 0.99A | 1bdwA-4gkvA:undetectable1bdwB-4gkvA:undetectable | 1bdwA-4gkvA:5.241bdwB-4gkvA:5.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hc6 | HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (Mycobacteriumtuberculosis) |
PF01648(ACPS) | 3 | VAL A 4VAL A 6TRP A 64 | None | 0.98A | 1bdwA-4hc6A:undetectable1bdwB-4hc6A:undetectable | 1bdwA-4hc6A:8.731bdwB-4hc6A:8.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwv | PECTATE LYASE/AMBALLERGEN (Acidovoraxcitrulli) |
PF00544(Pec_lyase_C) | 3 | VAL A 338VAL A 251TRP A 40 | None | 0.98A | 1bdwA-4hwvA:undetectable1bdwB-4hwvA:undetectable | 1bdwA-4hwvA:3.081bdwB-4hwvA:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ihq | FLAI ATPASE (Sulfolobusacidocaldarius) |
PF00437(T2SSE) | 3 | VAL A 286VAL A 334TRP A 301 | None | 0.78A | 1bdwA-4ihqA:undetectable1bdwB-4ihqA:undetectable | 1bdwA-4ihqA:7.501bdwB-4ihqA:7.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jkm | BETA-GLUCURONIDASE (Clostridiumperfringens) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 3 | VAL A 441VAL A 443TRP A 407 | None | 0.87A | 1bdwA-4jkmA:undetectable1bdwB-4jkmA:undetectable | 1bdwA-4jkmA:4.101bdwB-4jkmA:4.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kmr | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Sanguibacterkeddieii) |
PF13377(Peripla_BP_3) | 3 | VAL A 227VAL A 225TRP A 230 | None | 0.84A | 1bdwA-4kmrA:undetectable1bdwB-4kmrA:undetectable | 1bdwA-4kmrA:6.191bdwB-4kmrA:6.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kwy | PUTATIVEUNCHARACTERIZEDPROTEIN (Caulobactervibrioides) |
PF04390(LptE) | 3 | VAL A 100VAL A 120TRP A 102 | None | 0.98A | 1bdwA-4kwyA:undetectable1bdwB-4kwyA:undetectable | 1bdwA-4kwyA:8.091bdwB-4kwyA:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mx6 | TRAP-TYPEC4-DICARBOXYLATE:H+SYMPORT SYSTEMSUBSTRATE-BINDINGCOMPONENT DCTP (Shewanellaoneidensis) |
PF03480(DctP) | 3 | VAL A 318VAL A 314TRP A 319 | None | 0.85A | 1bdwA-4mx6A:undetectable1bdwB-4mx6A:undetectable | 1bdwA-4mx6A:3.851bdwB-4mx6A:3.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n9n | STEROL UPTAKECONTROL PROTEIN 2,LYSOZYME (Saccharomycescerevisiae;Escherichiavirus T4) |
PF00959(Phage_lysozyme)PF11951(Fungal_trans_2) | 3 | VAL A 866VAL A 875TRP A 867 | None | 0.96A | 1bdwA-4n9nA:undetectable1bdwB-4n9nA:undetectable | 1bdwA-4n9nA:3.161bdwB-4n9nA:3.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qp0 | ENDO-BETA-MANNANASE (Rhizomucormiehei) |
PF00150(Cellulase) | 3 | VAL A 215VAL A 217TRP A 170 | None | 0.68A | 1bdwA-4qp0A:undetectable1bdwB-4qp0A:undetectable | 1bdwA-4qp0A:5.021bdwB-4qp0A:5.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u28 | PHOSPHORIBOSYLISOMERASE A (Streptomycessviceus) |
PF00977(His_biosynth) | 3 | VAL A 14VAL A 22TRP A 45 | None | 0.93A | 1bdwA-4u28A:undetectable1bdwB-4u28A:undetectable | 1bdwA-4u28A:6.901bdwB-4u28A:6.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w6z | ALCOHOLDEHYDROGENASE 1 (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | VAL A 295VAL A 268TRP A 92 | 8ID A 403 (-3.5A)8ID A 403 (-3.9A)ETF A 404 (-3.3A) | 0.98A | 1bdwA-4w6zA:undetectable1bdwB-4w6zA:undetectable | 1bdwA-4w6zA:6.061bdwB-4w6zA:6.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd1 | ACETOACETATE-COALIGASE (Streptomyceslividans) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 3 | VAL A 59VAL A 65TRP A 62 | NoneEDO A 715 (-3.8A)None | 0.87A | 1bdwA-4wd1A:undetectable1bdwB-4wd1A:undetectable | 1bdwA-4wd1A:4.071bdwB-4wd1A:4.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x2r | 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO]IMIDAZOLE-4-CARBOXAMIDE ISOMERASE (Actinomycesurogenitalis) |
PF00977(His_biosynth) | 3 | VAL A 8VAL A 16TRP A 39 | None | 0.98A | 1bdwA-4x2rA:undetectable1bdwB-4x2rA:undetectable | 1bdwA-4x2rA:15.001bdwB-4x2rA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x6d | T-CELL SURFACEGLYCOPROTEIN CD1A (Homo sapiens) |
PF07654(C1-set)PF16497(MHC_I_3) | 3 | VAL A 12VAL A 98TRP A 31 | None | 0.61A | 1bdwA-4x6dA:undetectable1bdwB-4x6dA:undetectable | 1bdwA-4x6dA:3.751bdwB-4x6dA:3.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x9s | PHOSPHORIBOSYLISOMERASE A (Streptomycessp. Mg1) |
PF00977(His_biosynth) | 3 | VAL A 12VAL A 20TRP A 43 | None | 0.91A | 1bdwA-4x9sA:undetectable1bdwB-4x9sA:undetectable | 1bdwA-4x9sA:7.481bdwB-4x9sA:7.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xeq | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Desulfovibriovulgaris) |
PF03480(DctP) | 3 | VAL A 45VAL A 101TRP A 204 | NoneNonePAF A 401 (-3.7A) | 0.83A | 1bdwA-4xeqA:undetectable1bdwB-4xeqA:undetectable | 1bdwA-4xeqA:5.491bdwB-4xeqA:5.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xxw | PROTOCADHERIN-15 (Mus musculus) |
no annotation | 3 | VAL B 60VAL B 94TRP B 63 | None | 0.95A | 1bdwA-4xxwB:undetectable1bdwB-4xxwB:undetectable | 1bdwA-4xxwB:8.161bdwB-4xxwB:8.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ynu | GLUCOSE OXIDASE,PUTATIVE (Aspergillusflavus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 3 | VAL A 107VAL A 103TRP A 108 | None | 0.86A | 1bdwA-4ynuA:undetectable1bdwB-4ynuA:undetectable | 1bdwA-4ynuA:2.961bdwB-4ynuA:2.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z07 | CGMP-DEPENDENTPROTEIN KINASE 1 (Homo sapiens) |
PF00027(cNMP_binding) | 3 | VAL A 157VAL A 155TRP A 205 | None | 0.66A | 1bdwA-4z07A:undetectable1bdwB-4z07A:undetectable | 1bdwA-4z07A:5.191bdwB-4z07A:5.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5q | CYTOCHROME P450HYDROXYLASE (Streptomycesatroolivaceus) |
PF00067(p450) | 3 | VAL A 313VAL A 315TRP A 50 | None | 0.99A | 1bdwA-4z5qA:undetectable1bdwB-4z5qA:undetectable | 1bdwA-4z5qA:5.311bdwB-4z5qA:5.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5an9 | 60S RIBOSOMALPROTEIN L3 (Dictyosteliumdiscoideum) |
PF00297(Ribosomal_L3) | 3 | VAL A 87VAL A 163TRP A 106 | None | 0.92A | 1bdwA-5an9A:undetectable1bdwB-5an9A:undetectable | 1bdwA-5an9A:5.061bdwB-5an9A:5.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | ELONGATION FACTOR TUGTP-BINDINGDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF14492(EFG_II) | 3 | VAL K 232VAL K 144TRP K 268 | None | 0.93A | 1bdwA-5anbK:undetectable1bdwB-5anbK:undetectable | 1bdwA-5anbK:1.541bdwB-5anbK:1.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2v | HYDRAZINE SYNTHASEALPHA SUBUNIT (CandidatusKueneniastuttgartiensis) |
no annotation | 3 | VAL A 746VAL A 735TRP A 747 | None | 0.53A | 1bdwA-5c2vA:undetectable1bdwB-5c2vA:undetectable | 1bdwA-5c2vA:2.331bdwB-5c2vA:2.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9j | T-CELL SURFACEGLYCOPROTEINCD1C,T-CELL SURFACEGLYCOPROTEIN CD1B (Homo sapiens) |
PF07654(C1-set)PF16497(MHC_I_3) | 3 | VAL A 15VAL A 101TRP A 34 | STE A 303 ( 4.7A)NonePO4 A 308 (-3.2A) | 0.70A | 1bdwA-5c9jA:undetectable1bdwB-5c9jA:undetectable | 1bdwA-5c9jA:4.621bdwB-5c9jA:4.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9l | PLL LECTIN (Photorhabdusluminescens) |
PF03984(DUF346) | 3 | VAL A 91VAL A 89TRP A 99 | NoneNoneEDO A 413 (-3.6A) | 0.95A | 1bdwA-5c9lA:undetectable1bdwB-5c9lA:undetectable | 1bdwA-5c9lA:4.521bdwB-5c9lA:4.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ehk | LANTIBIOTICDEHYDRATASE (Microbisporacorallina) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 3 | VAL A 976VAL A 973TRP A 984 | None | 0.61A | 1bdwA-5ehkA:undetectable1bdwB-5ehkA:undetectable | 1bdwA-5ehkA:5.221bdwB-5ehkA:5.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw7 | GLUCOSIDASE YGJK (Escherichiacoli) |
PF01204(Trehalase) | 3 | VAL A 686VAL A 684TRP A 744 | None | 0.89A | 1bdwA-5gw7A:undetectable1bdwB-5gw7A:undetectable | 1bdwA-5gw7A:1.761bdwB-5gw7A:1.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hl6 | PUTATIVE GAF SENSORPROTEIN (Burkholderiavietnamiensis) |
PF13185(GAF_2) | 3 | VAL A 119VAL A 96TRP A 132 | None | 0.84A | 1bdwA-5hl6A:undetectable1bdwB-5hl6A:undetectable | 1bdwA-5hl6A:13.271bdwB-5hl6A:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6z | SODIUM-DEPENDENTSEROTONINTRANSPORTER (Homo sapiens) |
PF00209(SNF) | 3 | VAL A 102VAL A 97TRP A 103 | None | 0.75A | 1bdwA-5i6zA:undetectable1bdwB-5i6zA:undetectable | 1bdwA-5i6zA:2.871bdwB-5i6zA:2.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihx | TYROSINE--TRNALIGASE,MITOCHONDRIAL (Aspergillusnidulans) |
PF00579(tRNA-synt_1b) | 3 | VAL A 153VAL A 158TRP A 154 | None | 0.92A | 1bdwA-5ihxA:undetectable1bdwB-5ihxA:undetectable | 1bdwA-5ihxA:4.601bdwB-5ihxA:4.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja1 | ENTEROBACTINSYNTHASE COMPONENT F (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 3 | VAL A 753VAL A 755TRP A 652 | 75C A1301 (-4.7A)NoneNone | 0.98A | 1bdwA-5ja1A:undetectable1bdwB-5ja1A:undetectable | 1bdwA-5ja1A:2.261bdwB-5ja1A:2.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jx5 | GLUCANASE (Orpinomyces sp.Y102) |
PF01341(Glyco_hydro_6) | 3 | VAL A 400VAL A 327TRP A 401 | NoneNH4 A 516 (-3.6A)None | 0.96A | 1bdwA-5jx5A:undetectable1bdwB-5jx5A:undetectable | 1bdwA-5jx5A:5.471bdwB-5jx5A:5.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lxv | SCAFFOLDIN C (Ruminococcusflavefaciens) |
PF00963(Cohesin) | 3 | VAL A 55VAL A 107TRP A 91 | None | 0.91A | 1bdwA-5lxvA:undetectable1bdwB-5lxvA:undetectable | 1bdwA-5lxvA:8.741bdwB-5lxvA:8.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m2d | ENDOGLUCANASE-LIKEPROTEIN (Acremoniumchrysogenum) |
no annotation | 3 | VAL A 53VAL A 218TRP A 55 | None | 0.89A | 1bdwA-5m2dA:undetectable1bdwB-5m2dA:undetectable | 1bdwA-5m2dA:6.831bdwB-5m2dA:6.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mus | L PROTEIN (Californiareptarenavirus) |
no annotation | 3 | VAL A2013VAL A2004TRP A2030 | None | 0.95A | 1bdwA-5musA:undetectable1bdwB-5musA:undetectable | 1bdwA-5musA:3.401bdwB-5musA:3.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oee | LARGE SUBUNITTERMINASE (Phage D6E) |
no annotation | 3 | VAL A 260VAL A 325TRP A 275 | None | 0.81A | 1bdwA-5oeeA:undetectable1bdwB-5oeeA:undetectable | 1bdwA-5oeeA:3.941bdwB-5oeeA:3.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDD (Methanothermobacterwolfeii) |
PF01568(Molydop_binding) | 3 | VAL D 60VAL D 51TRP D 83 | None | 0.99A | 1bdwA-5t5iD:undetectable1bdwB-5t5iD:undetectable | 1bdwA-5t5iD:10.421bdwB-5t5iD:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tnu | DNA-DEPENDENT ATPASEXPBII (Sulfurisphaeratokodaii) |
no annotation | 3 | VAL A 221VAL A 89TRP A 80 | None | 0.97A | 1bdwA-5tnuA:undetectable1bdwB-5tnuA:undetectable | 1bdwA-5tnuA:3.451bdwB-5tnuA:3.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udy | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 7 (Homo sapiens) |
PF01663(Phosphodiest) | 3 | VAL A 191VAL A 36TRP A 127 | None | 0.94A | 1bdwA-5udyA:undetectable1bdwB-5udyA:undetectable | 1bdwA-5udyA:5.171bdwB-5udyA:5.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uk5 | NEUROGENIC LOCUSNOTCH HOMOLOGPROTEIN 1 (Rattusnorvegicus) |
PF00008(EGF)PF07645(EGF_CA) | 3 | VAL A 324VAL A 322TRP A 327 | FUC A 604 ( 4.9A)FUC A 604 (-4.4A)None | 0.70A | 1bdwA-5uk5A:undetectable1bdwB-5uk5A:undetectable | 1bdwA-5uk5A:3.471bdwB-5uk5A:3.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vbu | CYTOCHROME P45021-HYDROXYLASE (Homo sapiens) |
PF00067(p450) | 3 | VAL A 359VAL A 470TRP A 303 | HEM A 501 (-4.7A)NoneNone | 0.98A | 1bdwA-5vbuA:undetectable1bdwB-5vbuA:undetectable | 1bdwA-5vbuA:6.521bdwB-5vbuA:6.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vms | POTASSIUMVOLTAGE-GATEDCHANNEL SUBFAMILYKQT MEMBER 1 (Xenopus laevis) |
PF00520(Ion_trans)PF03520(KCNQ_channel) | 3 | VAL A 177VAL A 175TRP A 178 | None | 0.97A | 1bdwA-5vmsA:undetectable1bdwB-5vmsA:undetectable | 1bdwA-5vmsA:5.581bdwB-5vmsA:5.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 3 | VAL A 315VAL A 382TRP A 313 | None | 0.97A | 1bdwA-5wugA:undetectable1bdwB-5wugA:undetectable | 1bdwA-5wugA:undetectable1bdwB-5wugA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MEMBRANE-BOUNDHYDROGENASE SUBUNITALPHA (Pyrococcusfuriosus) |
no annotation | 3 | VAL L 327VAL L 337TRP L 339 | None | 0.68A | 1bdwA-6cfwL:undetectable1bdwB-6cfwL:undetectable | 1bdwA-6cfwL:undetectable1bdwB-6cfwL:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cv7 | - (-) |
no annotation | 3 | VAL A 60VAL A 94TRP A 63 | EDO A 407 (-4.2A)NoneNone | 0.95A | 1bdwA-6cv7A:undetectable1bdwB-6cv7A:undetectable | 1bdwA-6cv7A:undetectable1bdwB-6cv7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu6 | AMMONIUM TRANSPORTER (CandidatusKueneniastuttgartiensis) |
no annotation | 3 | VAL A 231VAL A 233TRP A 12 | None | 0.96A | 1bdwA-6eu6A:undetectable1bdwB-6eu6A:undetectable | 1bdwA-6eu6A:undetectable1bdwB-6eu6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9n | PRE-MRNA 3' ENDPROCESSING PROTEINWDR33 (Homo sapiens) |
no annotation | 3 | VAL B 135VAL B 124TRP B 146 | None | 0.90A | 1bdwA-6f9nB:undetectable1bdwB-6f9nB:undetectable | 1bdwA-6f9nB:undetectable1bdwB-6f9nB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fvs | CYS-LOOPLIGAND-GATED IONCHANNEL (endosymbiont ofTevniajerichonana) |
no annotation | 3 | VAL A 275VAL A 270TRP A 276 | None | 0.95A | 1bdwA-6fvsA:undetectable1bdwB-6fvsA:undetectable | 1bdwA-6fvsA:undetectable1bdwB-6fvsA:undetectable |