SIMILAR PATTERNS OF AMINO ACIDS FOR 1AVN_A_HSMA264

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ll2 GLYCOGENIN-1

(Oryctolagus
cuniculus) 		PF01501
(Glyco_transf_8) 		4 ASN A 188
HIS A 212
ASN A 133
GLN A 164
 None
MN  A 333 ( 3.4A)
UPG  A 334 (-3.4A)
UPG  A 334 (-2.9A)
 1.18A 1avnA-1ll2A:
0.0		 1avnA-1ll2A:
21.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qk3 CARBONIC ANHYDRASE 2

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 ASN A  62
HIS A  64
ASN A  67
GLN A  92
 None
 0.29A 1avnA-4qk3A:
43.8		 1avnA-4qk3A:
95.75