SIMILAR PATTERNS OF AMINO ACIDS FOR 1AV2_A_DVAA6_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bnl | COLLAGEN XVIII (Homo sapiens) |
PF06482(Endostatin) | 3 | ALA A 17VAL A 171TRP A 120 | None | 0.97A | 1av2A-1bnlA:undetectable1av2B-1bnlA:undetectable | 1av2A-1bnlA:11.211av2B-1bnlA:11.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) |
PF00089(Trypsin) | 3 | ALA A 55VAL A 99TRP A 215 | None0GJ A 1 ( 4.2A)None | 0.83A | 1av2A-1bqyA:undetectable1av2B-1bqyA:undetectable | 1av2A-1bqyA:7.011av2B-1bqyA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6m | DNA TOPOISOMERASEIII (Escherichiacoli) |
PF01131(Topoisom_bac)PF01751(Toprim) | 3 | ALA A 238VAL A 224TRP A 240 | None | 0.95A | 1av2A-1d6mA:undetectable1av2B-1d6mA:undetectable | 1av2A-1d6mA:3.411av2B-1d6mA:3.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezw | COENZYMEF420-DEPENDENTN5,N10-METHYLENETETRAHYDROMETHANOPTERINREDUCTASE (Methanopyruskandleri) |
PF00296(Bac_luciferase) | 3 | ALA A 130VAL A 154TRP A 117 | None | 0.97A | 1av2A-1ezwA:undetectable1av2B-1ezwA:undetectable | 1av2A-1ezwA:4.631av2B-1ezwA:4.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hzv | NITRITE REDUCTASE (Pseudomonasaeruginosa) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 3 | ALA A 48VAL A 53TRP A 246 | None | 0.89A | 1av2A-1hzvA:undetectable1av2B-1hzvA:undetectable | 1av2A-1hzvA:4.441av2B-1hzvA:4.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 3 | ALA A 335VAL A 338TRP A 378 | None | 0.82A | 1av2A-1kfwA:undetectable1av2B-1kfwA:undetectable | 1av2A-1kfwA:3.191av2B-1kfwA:3.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1l | RIBONUCLEOSIDETRIPHOSPHATEREDUCTASE (Lactobacillusleichmannii) |
PF02867(Ribonuc_red_lgC) | 3 | ALA A 321VAL A 163TRP A 120 | None | 0.87A | 1av2A-1l1lA:undetectable1av2B-1l1lA:undetectable | 1av2A-1l1lA:2.701av2B-1l1lA:2.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1l | RIBONUCLEOSIDETRIPHOSPHATEREDUCTASE (Lactobacillusleichmannii) |
PF02867(Ribonuc_red_lgC) | 3 | ALA A 646VAL A 547TRP A 642 | None | 0.91A | 1av2A-1l1lA:undetectable1av2B-1l1lA:undetectable | 1av2A-1l1lA:2.701av2B-1l1lA:2.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7u | ADSORPTION PROTEINP2 (Salmonellavirus PRD1) |
PF09214(Prd1-P2) | 3 | ALA A 499VAL A 6TRP A 501 | None | 0.97A | 1av2A-1n7uA:undetectable1av2B-1n7uA:undetectable | 1av2A-1n7uA:2.711av2B-1n7uA:2.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1npm | NEUROPSIN (Mus musculus) |
PF00089(Trypsin) | 3 | ALA A 32VAL A 45TRP A 29 | None | 0.91A | 1av2A-1npmA:undetectable1av2B-1npmA:undetectable | 1av2A-1npmA:5.261av2B-1npmA:5.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odo | PUTATIVE CYTOCHROMEP450 154A1 (Streptomycescoelicolor) |
PF00067(p450) | 3 | ALA A 184VAL A 174TRP A 81 | NoneNonePIM A1408 (-4.6A) | 0.78A | 1av2A-1odoA:undetectable1av2B-1odoA:undetectable | 1av2A-1odoA:14.861av2B-1odoA:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ppr | PERIDININ-CHLOROPHYLL PROTEIN (Amphidiniumcarterae) |
PF02429(PCP) | 3 | ALA M 238VAL M 241TRP M 186 | NonePID M 624 (-4.2A)PID M 624 ( 3.6A) | 0.93A | 1av2A-1pprM:undetectable1av2B-1pprM:undetectable | 1av2A-1pprM:7.101av2B-1pprM:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfc | PROTEIN (PURPLE ACIDPHOSPHATASE) (Rattusnorvegicus) |
PF00149(Metallophos) | 3 | ALA A 241VAL A 12TRP A 15 | None | 0.86A | 1av2A-1qfcA:undetectable1av2B-1qfcA:undetectable | 1av2A-1qfcA:5.001av2B-1qfcA:5.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhq | PROTEIN (AURACYANIN) (Chloroflexusaurantiacus) |
PF00127(Copper-bind) | 3 | ALA A 23VAL A 21TRP A 59 | None | 0.87A | 1av2A-1qhqA:undetectable1av2B-1qhqA:undetectable | 1av2A-1qhqA:6.431av2B-1qhqA:6.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rbl | RIBULOSE 1,5BISPHOSPHATECARBOXYLASE/OXYGENASE (LARGE CHAIN) (Synechococcuselongatus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ALA A 15VAL A 69TRP A 70 | None | 0.78A | 1av2A-1rblA:undetectable1av2B-1rblA:undetectable | 1av2A-1rblA:4.081av2B-1rblA:4.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1to3 | PUTATIVE ALDOLASEYIHT (Salmonellaenterica) |
PF01791(DeoC) | 3 | ALA A 274VAL A 255TRP A 256 | None | 0.90A | 1av2A-1to3A:undetectable1av2B-1to3A:undetectable | 1av2A-1to3A:6.401av2B-1to3A:6.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tue | REGULATORY PROTEINE2 (Alphapapillomavirus7) |
PF00508(PPV_E2_N) | 3 | ALA B 154VAL B 141TRP B 138 | None | 0.95A | 1av2A-1tueB:undetectable1av2B-1tueB:undetectable | 1av2A-1tueB:5.701av2B-1tueB:5.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5w | HYPOTHETICAL UPF0244PROTEIN YJJX (Escherichiacoli) |
PF01931(NTPase_I-T) | 3 | ALA A 77VAL A 8TRP A 75 | None | 0.91A | 1av2A-1u5wA:undetectable1av2B-1u5wA:undetectable | 1av2A-1u5wA:6.181av2B-1u5wA:6.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 3 | ALA A 174VAL A 369TRP A 365 | None | 0.78A | 1av2A-1u7gA:undetectable1av2B-1u7gA:undetectable | 1av2A-1u7gA:5.191av2B-1u7gA:5.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1up2 | CELA1 PROTEIN (Mycobacteriumtuberculosis) |
PF01341(Glyco_hydro_6) | 3 | ALA A 137VAL A 139TRP A 186 | None | 0.93A | 1av2A-1up2A:undetectable1av2B-1up2A:undetectable | 1av2A-1up2A:6.251av2B-1up2A:6.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y43 | ASPERGILLOPEPSIN IIHEAVY CHAIN (Aspergillusniger) |
PF01828(Peptidase_A4) | 3 | ALA B 9VAL B 11TRP B 107 | None | 0.48A | 1av2A-1y43B:undetectable1av2B-1y43B:undetectable | 1av2A-1y43B:6.131av2B-1y43B:6.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a7w | PHOSPHORIBOSYL-ATPPYROPHOSPHATASE (Chromobacteriumviolaceum) |
PF01503(PRA-PH) | 3 | ALA A 45VAL A 64TRP A 68 | None | 0.81A | 1av2A-2a7wA:undetectable1av2B-2a7wA:undetectable | 1av2A-2a7wA:8.041av2B-2a7wA:8.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2btd | PTS-DEPENDENTDIHYDROXYACETONEKINASE (Escherichiacoli) |
PF02734(Dak2) | 3 | ALA A 123VAL A 117TRP A 134 | ADP A1211 ( 4.4A)NoneNone | 0.93A | 1av2A-2btdA:undetectable1av2B-2btdA:undetectable | 1av2A-2btdA:7.521av2B-2btdA:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2co6 | PUTATIVE FIMBRIAEASSEMBLY CHAPERONE (Salmonellaenterica) |
PF00345(PapD_N)PF02753(PapD_C) | 3 | ALA B 168VAL B 170TRP B 203 | None | 0.83A | 1av2A-2co6B:undetectable1av2B-2co6B:undetectable | 1av2A-2co6B:8.051av2B-2co6B:8.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cwf | DELTA1-PIPERIDEINE-2-CARBOXYLATEREDUCTASE (Pseudomonassyringae groupgenomosp. 3) |
PF02615(Ldh_2) | 3 | ALA A 67VAL A 71TRP A 70 | None | 0.91A | 1av2A-2cwfA:undetectable1av2B-2cwfA:undetectable | 1av2A-2cwfA:6.221av2B-2cwfA:6.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3y | URACIL-DNAGLYCOSYLASE (Thermusthermophilus) |
PF03167(UDG) | 3 | ALA A 116VAL A 43TRP A 39 | None | 0.85A | 1av2A-2d3yA:undetectable1av2B-2d3yA:undetectable | 1av2A-2d3yA:8.731av2B-2d3yA:8.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4w | GLYCEROL KINASE (Cellulomonassp.) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | ALA A 85VAL A 101TRP A 102 | NoneNoneMPD A 1 ( 3.9A) | 0.89A | 1av2A-2d4wA:undetectable1av2B-2d4wA:undetectable | 1av2A-2d4wA:4.981av2B-2d4wA:4.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ffi | 2-PYRONE-4,6-DICARBOXYLIC ACIDHYDROLASE, PUTATIVE (Pseudomonasputida) |
PF04909(Amidohydro_2) | 3 | ALA A 215VAL A 198TRP A 233 | None | 0.89A | 1av2A-2ffiA:undetectable1av2B-2ffiA:undetectable | 1av2A-2ffiA:5.681av2B-2ffiA:5.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hqm | GLUTATHIONEREDUCTASE (Saccharomycescerevisiae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 3 | ALA A 213VAL A 215TRP A 73 | None | 0.97A | 1av2A-2hqmA:undetectable1av2B-2hqmA:undetectable | 1av2A-2hqmA:3.191av2B-2hqmA:3.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lpu | KMATG10 (Kluyveromycesmarxianus) |
PF03987(Autophagy_act_C) | 3 | ALA A 120VAL A 122TRP A 133 | None | 0.91A | 1av2A-2lpuA:undetectable1av2B-2lpuA:undetectable | 1av2A-2lpuA:8.261av2B-2lpuA:8.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvn | HYPOTHETICAL PROTEIN (Synechococcuselongatus) |
PF08848(DUF1818) | 3 | ALA A 106VAL A 108TRP A 103 | None | 0.95A | 1av2A-2nvnA:undetectable1av2B-2nvnA:undetectable | 1av2A-2nvnA:10.481av2B-2nvnA:10.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pnc | COPPER AMINEOXIDASE, LIVERISOZYME (Bos taurus) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 3 | ALA A 427VAL A 464TRP A 474 | None | 0.95A | 1av2A-2pncA:undetectable1av2B-2pncA:undetectable | 1av2A-2pncA:3.081av2B-2pncA:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vob | TRYPANOTHIONESYNTHETASE (Leishmaniamajor) |
PF03738(GSP_synth)PF05257(CHAP) | 3 | ALA A 32VAL A 30TRP A 66 | None | 0.97A | 1av2A-2vobA:undetectable1av2B-2vobA:undetectable | 1av2A-2vobA:3.501av2B-2vobA:3.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vtc | CEL61B (Trichodermareesei) |
PF03443(Glyco_hydro_61) | 3 | ALA A 226VAL A 116TRP A 228 | None | 0.92A | 1av2A-2vtcA:undetectable1av2B-2vtcA:undetectable | 1av2A-2vtcA:4.841av2B-2vtcA:4.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axx | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 3 | ALA A 271VAL A 298TRP A 323 | None | 0.77A | 1av2A-3axxA:undetectable1av2B-3axxA:undetectable | 1av2A-3axxA:3.231av2B-3axxA:3.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e2s | PROLINEDEHYDROGENASE (Escherichiacoli) |
PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | ALA A 405VAL A 455TRP A 438 | NoneNoneFAD A2001 (-3.6A) | 0.81A | 1av2A-3e2sA:undetectable1av2B-3e2sA:undetectable | 1av2A-3e2sA:1.861av2B-3e2sA:1.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fsc | QDTC (Thermoanaerobacteriumthermosaccharolyticum) |
PF00132(Hexapep) | 3 | ALA A 195VAL A 178TRP A 239 | None | 0.96A | 1av2A-3fscA:undetectable1av2B-3fscA:undetectable | 1av2A-3fscA:13.891av2B-3fscA:13.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i2t | EPIDERMAL GROWTHFACTOR RECEPTOR,ISOFORM A (Drosophilamelanogaster) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 3 | ALA A 405VAL A 430TRP A 457 | None | 0.88A | 1av2A-3i2tA:undetectable1av2B-3i2tA:undetectable | 1av2A-3i2tA:3.281av2B-3i2tA:3.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ian | CHITINASE (Lactococcuslactis) |
PF00704(Glyco_hydro_18) | 3 | ALA A 327VAL A 323TRP A 49 | EDO A 364 ( 4.2A)NoneNone | 0.95A | 1av2A-3ianA:undetectable1av2B-3ianA:undetectable | 1av2A-3ianA:3.251av2B-3ianA:3.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcx | FAB E HEAVY CHAIN (Rattusnorvegicus) |
PF07686(V-set) | 3 | ALA H 192VAL H 135TRP H 213 | None | 0.97A | 1av2A-3jcxH:undetectable1av2B-3jcxH:undetectable | 1av2A-3jcxH:9.351av2B-3jcxH:9.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8h | PUTATIVE HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bordetellabronchiseptica) |
PF13242(Hydrolase_like) | 3 | ALA A 134VAL A 124TRP A 142 | None | 0.94A | 1av2A-3l8hA:undetectable1av2B-3l8hA:undetectable | 1av2A-3l8hA:9.681av2B-3l8hA:9.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njb | ENOYL-COA HYDRATASE (Mycolicibacteriumsmegmatis) |
PF00378(ECH_1) | 3 | ALA A 281VAL A 283TRP A 177 | None | 0.88A | 1av2A-3njbA:undetectable1av2B-3njbA:undetectable | 1av2A-3njbA:6.801av2B-3njbA:6.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oft | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 3 | ALA A 342VAL A 340TRP A 61 | NoneNoneHEM A 417 (-4.1A) | 0.59A | 1av2A-3oftA:undetectable1av2B-3oftA:undetectable | 1av2A-3oftA:19.641av2B-3oftA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pty | ARABINOSYLTRANSFERASE C (Mycobacteriumtuberculosis) |
PF14896(Arabino_trans_C) | 3 | ALA A 771VAL A 769TRP A 868 | None | 0.87A | 1av2A-3ptyA:undetectable1av2B-3ptyA:undetectable | 1av2A-3ptyA:3.981av2B-3ptyA:3.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3riq | TAILSPIKE PROTEIN (Salmonellavirus 9NA) |
PF09251(PhageP22-tail) | 3 | ALA A 414VAL A 412TRP A 457 | None | 0.88A | 1av2A-3riqA:undetectable1av2B-3riqA:undetectable | 1av2A-3riqA:2.241av2B-3riqA:2.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w36 | NAPH1 (Streptomycessp. CNQ525) |
no annotation | 3 | ALA A 186VAL A 98TRP A 146 | None | 0.90A | 1av2A-3w36A:undetectable1av2B-3w36A:undetectable | 1av2A-3w36A:4.621av2B-3w36A:4.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w6m | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 3 | ALA A 271VAL A 298TRP A 323 | None | 0.74A | 1av2A-3w6mA:undetectable1av2B-3w6mA:undetectable | 1av2A-3w6mA:3.531av2B-3w6mA:3.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwe | OXIDIZED POLYVINYLALCOHOL HYDROLASE (Pseudomonas sp.VM15C) |
no annotation | 3 | ALA A 50VAL A 92TRP A 60 | None | 0.97A | 1av2A-3wweA:undetectable1av2B-3wweA:undetectable | 1av2A-3wweA:4.601av2B-3wweA:4.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akk | NITRATE REGULATORYPROTEIN (Klebsiellaoxytoca) |
PF03861(ANTAR)PF08376(NIT) | 3 | ALA A 124VAL A 118TRP A 56 | None | 0.93A | 1av2A-4akkA:undetectable1av2B-4akkA:undetectable | 1av2A-4akkA:3.241av2B-4akkA:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akk | NITRATE REGULATORYPROTEIN (Klebsiellaoxytoca) |
PF03861(ANTAR)PF08376(NIT) | 3 | ALA A 125VAL A 118TRP A 56 | None | 0.86A | 1av2A-4akkA:undetectable1av2B-4akkA:undetectable | 1av2A-4akkA:3.241av2B-4akkA:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4di1 | ENOYL-COA HYDRATASEECHA17 (Mycobacteriummarinum) |
PF00378(ECH_1) | 3 | ALA A 49VAL A 98TRP A 192 | None | 0.87A | 1av2A-4di1A:undetectable1av2B-4di1A:undetectable | 1av2A-4di1A:17.391av2B-4di1A:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4epa | PESTICIN RECEPTOR (Yersinia pestis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | ALA A 468VAL A 470TRP A 513 | None | 0.76A | 1av2A-4epaA:undetectable1av2B-4epaA:undetectable | 1av2A-4epaA:2.151av2B-4epaA:2.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fom | POLIOVIRUSRECEPTOR-RELATEDPROTEIN 3 (Homo sapiens) |
PF07686(V-set)PF08205(C2-set_2) | 3 | ALA A 68VAL A 168TRP A 70 | NoneNAG A 415 ( 4.6A)NAG A 415 ( 4.1A) | 0.96A | 1av2A-4fomA:undetectable1av2B-4fomA:undetectable | 1av2A-4fomA:4.861av2B-4fomA:4.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ftd | UNCHARACTERIZEDPROTEIN (Bacteroideseggerthii) |
PF15416(DUF4623) | 3 | ALA A 362VAL A 323TRP A 334 | None | 0.81A | 1av2A-4ftdA:undetectable1av2B-4ftdA:undetectable | 1av2A-4ftdA:2.431av2B-4ftdA:2.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hi4 | AEROTAXIS TRANSDUCERAER2 (Pseudomonasaeruginosa) |
PF13188(PAS_8) | 3 | ALA A 184VAL A 202TRP A 283 | None | 0.51A | 1av2A-4hi4A:undetectable1av2B-4hi4A:undetectable | 1av2A-4hi4A:8.741av2B-4hi4A:8.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6k | AMIDOHYDROLASEFAMILY PROTEIN (Acinetobacterbaumannii) |
PF04909(Amidohydro_2) | 3 | ALA A 205VAL A 189TRP A 223 | None | 0.92A | 1av2A-4i6kA:undetectable1av2B-4i6kA:undetectable | 1av2A-4i6kA:6.031av2B-4i6kA:6.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i9r | CELLULAR RETINOICACID-BINDING PROTEIN2 (Homo sapiens) |
PF00061(Lipocalin) | 3 | ALA A 35VAL A 33TRP A 32 | NoneNoneRET A 201 (-4.5A) | 0.85A | 1av2A-4i9rA:undetectable1av2B-4i9rA:undetectable | 1av2A-4i9rA:10.481av2B-4i9rA:10.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j4j | DNA DC->DU-EDITINGENZYME APOBEC-3F (Homo sapiens) |
PF08210(APOBEC_N) | 3 | ALA A 250VAL A 242TRP A 277 | None | 0.78A | 1av2A-4j4jA:undetectable1av2B-4j4jA:undetectable | 1av2A-4j4jA:5.671av2B-4j4jA:5.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jpq | UNCHARACTERIZEDPROTEIN (Bacteroidesuniformis) |
PF16011(CBM9_2) | 3 | ALA A 101VAL A 103TRP A 185 | None | 0.96A | 1av2A-4jpqA:undetectable1av2B-4jpqA:undetectable | 1av2A-4jpqA:8.111av2B-4jpqA:8.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kna | N-SUCCINYLGLUTAMATE5-SEMIALDEHYDEDEHYDROGENASE (Burkholderiathailandensis) |
PF00171(Aldedh) | 3 | ALA A 180VAL A 182TRP A 185 | None | 0.91A | 1av2A-4knaA:undetectable1av2B-4knaA:undetectable | 1av2A-4knaA:2.721av2B-4knaA:2.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2j | AMINOTRANSFERASE (Streptomyceslavendulae) |
PF00155(Aminotran_1_2) | 3 | ALA A 239VAL A 85TRP A 236 | None | 0.85A | 1av2A-4m2jA:undetectable1av2B-4m2jA:undetectable | 1av2A-4m2jA:3.691av2B-4m2jA:3.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7r | ANAMORSIN (Homo sapiens) |
PF08241(Methyltransf_11) | 3 | ALA A 37VAL A 68TRP A 40 | None | 0.91A | 1av2A-4m7rA:undetectable1av2B-4m7rA:undetectable | 1av2A-4m7rA:9.911av2B-4m7rA:9.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkv | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Pisum sativum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ALA A 15VAL A 69TRP A 70 | None | 0.73A | 1av2A-4mkvA:undetectable1av2B-4mkvA:undetectable | 1av2A-4mkvA:3.791av2B-4mkvA:3.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mpt | PUTATIVELEU/ILE/VAL-BINDINGPROTEIN (Bordetellapertussis) |
PF13458(Peripla_BP_6) | 3 | ALA A 298VAL A 301TRP A 285 | None | 0.93A | 1av2A-4mptA:undetectable1av2B-4mptA:undetectable | 1av2A-4mptA:5.631av2B-4mptA:5.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 3 | ALA A 277VAL A 326TRP A 310 | NoneNoneP5F A1101 (-3.6A) | 0.82A | 1av2A-4nmeA:undetectable1av2B-4nmeA:undetectable | 1av2A-4nmeA:2.231av2B-4nmeA:2.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8a | BIFUNCTIONAL PROTEINPUTA (Escherichiacoli) |
PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | ALA A 405VAL A 455TRP A 438 | NoneNoneFAD A2001 (-3.5A) | 0.81A | 1av2A-4o8aA:undetectable1av2B-4o8aA:undetectable | 1av2A-4o8aA:3.021av2B-4o8aA:3.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4og1 | ENOYL-COAHYDRATASE/ISOMERASE (Novosphingobiumaromaticivorans) |
PF00378(ECH_1) | 3 | ALA A 154VAL A 125TRP A 103 | None | 0.87A | 1av2A-4og1A:undetectable1av2B-4og1A:undetectable | 1av2A-4og1A:7.561av2B-4og1A:7.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqr | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 3 | ALA A 290VAL A 308TRP A 48 | None | 0.92A | 1av2A-4oqrA:undetectable1av2B-4oqrA:undetectable | 1av2A-4oqrA:3.201av2B-4oqrA:3.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqs | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 3 | ALA A 290VAL A 308TRP A 48 | None | 0.91A | 1av2A-4oqsA:undetectable1av2B-4oqsA:undetectable | 1av2A-4oqsA:3.201av2B-4oqsA:3.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvi | GH62 HYDROLASE (Mycothermusthermophilus) |
PF03664(Glyco_hydro_62) | 3 | ALA A 288VAL A 290TRP A 34 | None | 0.70A | 1av2A-4pviA:undetectable1av2B-4pviA:undetectable | 1av2A-4pviA:3.271av2B-4pviA:3.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q73 | PROLINEDEHYDROGENASE (Bradyrhizobiumdiazoefficiens) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | ALA A 313VAL A 363TRP A 346 | NoneNoneFAD A2001 (-3.6A) | 0.82A | 1av2A-4q73A:undetectable1av2B-4q73A:undetectable | 1av2A-4q73A:2.581av2B-4q73A:2.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ruw | ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE (Beutenbergiacavernae) |
PF03372(Exo_endo_phos) | 3 | ALA A 195VAL A 181TRP A 124 | None | 0.93A | 1av2A-4ruwA:undetectable1av2B-4ruwA:undetectable | 1av2A-4ruwA:3.081av2B-4ruwA:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7m | BETA-XYLOSIDASE (Trichodermareesei) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 3 | ALA A 578VAL A 529TRP A 501 | None | 0.75A | 1av2A-5a7mA:undetectable1av2B-5a7mA:undetectable | 1av2A-5a7mA:1.951av2B-5a7mA:1.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITALPHA (Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 3 | ALA A 166VAL A 213TRP A 229 | None | 0.83A | 1av2A-5a8rA:undetectable1av2B-5a8rA:undetectable | 1av2A-5a8rA:4.081av2B-5a8rA:4.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aca | VP1 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 3 | ALA 1 50VAL 1 173TRP 1 89 | None | 0.89A | 1av2A-5aca1:undetectable1av2B-5aca1:undetectable | 1av2A-5aca1:10.611av2B-5aca1:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 3 | ALA A 355VAL A 391TRP A 368 | None | 0.91A | 1av2A-5cjuA:undetectable1av2B-5cjuA:undetectable | 1av2A-5cjuA:2.131av2B-5cjuA:2.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7l | CONTACTIN-2 (Mus musculus) |
PF00041(fn3) | 3 | ALA A 819VAL A 821TRP A 835 | None | 0.96A | 1av2A-5e7lA:undetectable1av2B-5e7lA:undetectable | 1av2A-5e7lA:10.671av2B-5e7lA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ebb | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3A (Homo sapiens) |
PF00149(Metallophos) | 3 | ALA A 318VAL A 43TRP A 107 | None | 0.90A | 1av2A-5ebbA:undetectable1av2B-5ebbA:undetectable | 1av2A-5ebbA:3.981av2B-5ebbA:3.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewn | STRUCTURAL PROTEIN (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | ALA A 376VAL A 353TRP A 351 | None | 0.97A | 1av2A-5ewnA:undetectable1av2B-5ewnA:undetectable | 1av2A-5ewnA:6.371av2B-5ewnA:6.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewn | STRUCTURAL PROTEIN (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | ALA A 376VAL A 369TRP A 351 | None | 0.87A | 1av2A-5ewnA:undetectable1av2B-5ewnA:undetectable | 1av2A-5ewnA:6.371av2B-5ewnA:6.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fca | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3A (Mus musculus) |
PF00149(Metallophos) | 3 | ALA A 315VAL A 40TRP A 104 | None | 0.93A | 1av2A-5fcaA:undetectable1av2B-5fcaA:undetectable | 1av2A-5fcaA:5.501av2B-5fcaA:5.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g06 | EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae) |
PF14382(ECR1_N)PF15985(KH_6) | 3 | ALA H 117VAL H 119TRP H 124 | None | 0.75A | 1av2A-5g06H:undetectable1av2B-5g06H:undetectable | 1av2A-5g06H:4.711av2B-5g06H:4.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | ALA A 376VAL A 369TRP A 351 | None | 0.96A | 1av2A-5ibvA:undetectable1av2B-5ibvA:undetectable | 1av2A-5ibvA:6.861av2B-5ibvA:6.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf7 | BIFUNCTIONAL PROTEINPUTA (Sinorhizobiummeliloti) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | ALA A 341VAL A 391TRP A 374 | NoneNoneFAD A2001 (-3.6A) | 0.81A | 1av2A-5kf7A:undetectable1av2B-5kf7A:undetectable | 1av2A-5kf7A:1.641av2B-5kf7A:1.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 3 | ALA B 478VAL B 472TRP B 473 | None | 0.56A | 1av2A-5kohB:undetectable1av2B-5kohB:undetectable | 1av2A-5kohB:3.101av2B-5kohB:3.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lb8 | ATP-DEPENDENT DNAHELICASE Q5 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF16124(RecQ_Zn_bind) | 3 | ALA A 286VAL A 310TRP A 305 | None | 0.97A | 1av2A-5lb8A:undetectable1av2B-5lb8A:undetectable | 1av2A-5lb8A:4.121av2B-5lb8A:4.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lpe | KALLIKREIN-10 (Homo sapiens) |
PF00089(Trypsin) | 3 | ALA A 43VAL A 45TRP A 29 | None | 0.76A | 1av2A-5lpeA:undetectable1av2B-5lpeA:undetectable | 1av2A-5lpeA:11.251av2B-5lpeA:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ms3 | KALLIKREIN-8 (Homo sapiens) |
no annotation | 3 | ALA A 32VAL A 45TRP A 29 | None | 0.93A | 1av2A-5ms3A:undetectable1av2B-5ms3A:undetectable | 1av2A-5ms3A:undetectable1av2B-5ms3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanotorrisformicicus) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 3 | ALA A 166VAL A 213TRP A 229 | None | 0.80A | 1av2A-5n28A:undetectable1av2B-5n28A:undetectable | 1av2A-5n28A:2.321av2B-5n28A:2.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv3 | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Rhodobactersphaeroides) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ALA A 16VAL A 71TRP A 72 | None | 0.71A | 1av2A-5nv3A:undetectable1av2B-5nv3A:undetectable | 1av2A-5nv3A:3.901av2B-5nv3A:3.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o7g | ALPHA/BETA HYDROLASEFAMILY PROTEIN (Bacilluscoagulans) |
no annotation | 3 | ALA A 71VAL A 65TRP A 80 | None | 0.89A | 1av2A-5o7gA:undetectable1av2B-5o7gA:undetectable | 1av2A-5o7gA:undetectable1av2B-5o7gA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5okz | EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae) |
PF14382(ECR1_N)PF15985(KH_6) | 3 | ALA H 117VAL H 119TRP H 124 | None | 0.87A | 1av2A-5okzH:undetectable1av2B-5okzH:undetectable | 1av2A-5okzH:5.081av2B-5okzH:5.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tkm | DNA DC->DU-EDITINGENZYME APOBEC-3B (Homo sapiens) |
PF08210(APOBEC_N) | 3 | ALA A 67VAL A 59TRP A 94 | None | 0.85A | 1av2A-5tkmA:undetectable1av2B-5tkmA:undetectable | 1av2A-5tkmA:6.541av2B-5tkmA:6.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u0s | MEDIATOR COMPLEXSUBUNIT 8MEDIATOR COMPLEXSUBUNIT 18 (Schizosaccharomycespombe;Schizosaccharomycespombe) |
PF10232(Med8)PF09637(Med18) | 3 | ALA H 184VAL R 10TRP R 165 | None | 0.93A | 1av2A-5u0sH:undetectable1av2B-5u0sH:undetectable | 1av2A-5u0sH:6.201av2B-5u0sH:6.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1o | GLUTATHIONEREDUCTASE (Vibrioparahaemolyticus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 3 | ALA A 187VAL A 189TRP A 58 | None | 0.97A | 1av2A-5u1oA:undetectable1av2B-5u1oA:undetectable | 1av2A-5u1oA:12.501av2B-5u1oA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 3 | ALA A 63VAL A 66TRP A 59 | None | 0.79A | 1av2A-5uldA:undetectable1av2B-5uldA:undetectable | 1av2A-5uldA:2.971av2B-5uldA:2.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur2 | BIFUNCTIONAL PROTEINPUTA (Bdellovibriobacteriovorus) |
PF00171(Aldedh)PF01619(Pro_dh) | 3 | ALA A 272VAL A 321TRP A 305 | NoneNoneP5F A1001 (-3.7A) | 0.89A | 1av2A-5ur2A:undetectable1av2B-5ur2A:undetectable | 1av2A-5ur2A:2.821av2B-5ur2A:2.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vf4 | UNCHARACTERIZEDPROTEIN (Thermusaquaticus) |
PF03781(FGE-sulfatase) | 3 | ALA A 90VAL A 373TRP A 201 | None | 0.85A | 1av2A-5vf4A:undetectable1av2B-5vf4A:undetectable | 1av2A-5vf4A:6.061av2B-5vf4A:6.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsx | CHITINASE (Thermococcuschitonophagus) |
no annotation | 3 | ALA A 646VAL A 680TRP A 682 | None | 0.89A | 1av2A-5xsxA:undetectable1av2B-5xsxA:undetectable | 1av2A-5xsxA:undetectable1av2B-5xsxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yim | SDEA (Legionellapneumophila) |
no annotation | 3 | ALA A 399VAL A 401TRP A 394 | None | 0.73A | 1av2A-5yimA:undetectable1av2B-5yimA:undetectable | 1av2A-5yimA:undetectable1av2B-5yimA:undetectable |