SIMILAR PATTERNS OF AMINO ACIDS FOR 1ALZ_B_DVAB6

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v69 PROTEIN FILIA

(Mus musculus) 		PF16005
(MOEP19) 		4 TRP A  87
TRP A  78
ALA A   2
VAL A  75
 None
 1.42A 1alzA-3v69A:
undetectable
1alzB-3v69A:
undetectable		 1alzA-3v69A:
6.57
1alzB-3v69A:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfe EXODEOXYRIBONUCLEASE

(Bacillus
subtilis) 		PF03372
(Exo_endo_phos) 		4 TRP A   6
TRP A 201
ALA A 236
VAL A 246
 None
 1.22A 1alzA-5cfeA:
undetectable
1alzB-5cfeA:
undetectable		 1alzA-5cfeA:
4.48
1alzB-5cfeA:
5.67