SIMILAR PATTERNS OF AMINO ACIDS FOR 1AJ0_A_SANA561_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmb FOLIC ACID SYNTHESIS
PROTEIN FOL1

(Saccharomyces
cerevisiae) 		PF00809
(Pterin_bind)
PF01288
(HPPK) 		4 ARG A 598
ARG A 806
LYS A 807
HIS A 844
 PMM  A1865 (-4.1A)
None
PMM  A1865 (-2.8A)
PMM  A1865 (-4.0A)
 0.78A 1aj0A-2bmbA:
33.9		 1aj0A-2bmbA:
21.49