SIMILAR PATTERNS OF AMINO ACIDS FOR 11GS_B_EAAB211_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8x PROTEIN (AML-1B)

(Escherichia
coli) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   6
GLY A  11
TYR A 110
GLY A 204
 None
 0.59A 11gsB-1b8xA:
23.9		 11gsB-1b8xA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8x PROTEIN (AML-1B)

(Escherichia
coli) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 110
GLY A 204
TYR A   6
GLY A  11
 None
 0.82A 11gsB-1b8xA:
23.9		 11gsB-1b8xA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhg BETA-GLUCURONIDASE

(Homo sapiens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		5 GLY A 583
ARG A 577
ILE A 629
TYR A 626
GLY A 347
 None
 1.48A 11gsB-1bhgA:
undetectable		 11gsB-1bhgA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evj GLUCOSE-FRUCTOSE
OXIDOREDUCTASE

(Zymomonas
mobilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 GLY A 215
ILE A 359
TYR A 360
GLY A 209
 None
 0.83A 11gsB-1evjA:
undetectable		 11gsB-1evjA:
18.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN

(Mus musculus) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 TYR A   8
PHE A   9
GLY A  13
ARG A  14
 GBX  A 223 (-4.9A)
GBX  A 223 (-3.7A)
GBX  A 223 ( 4.5A)
GBX  A 223 (-3.8A)
 0.69A 11gsB-1f3bA:
23.6		 11gsB-1f3bA:
30.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3l PROTEIN ARGININE
METHYLTRANSFERASE
PRMT3

(Rattus
norvegicus) 		PF06325
(PrmA) 		4 TYR A 330
PHE A 334
ILE A 226
TYR A 221
 None
None
None
SAH  A 529 (-3.5A)
 0.78A 11gsB-1f3lA:
undetectable		 11gsB-1f3lA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fhe GLUTATHIONE
TRANSFERASE

(Fasciola
hepatica) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   6
GLY A  11
TYR A 110
GLY A 204
 None
 0.73A 11gsB-1fheA:
24.7		 11gsB-1fheA:
29.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gsq GLUTATHIONE
S-TRANSFERASE

(Todarodes
pacificus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
PHE A   8
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
GDN  A 203 (-4.9A)
 0.46A 11gsB-1gsqA:
25.7		 11gsB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6d PRECURSOR FORM OF
GLUCOSE-FRUCTOSE
OXIDOREDUCTASE

(Zymomonas
mobilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 GLY A 267
ILE A 411
TYR A 412
GLY A 261
 None
 0.82A 11gsB-1h6dA:
undetectable		 11gsB-1h6dA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F

(Corynebacterium
ammoniagenes) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.76A 11gsB-1kgpA:
undetectable		 11gsB-1kgpA:
20.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
GLY A  12
ARG A  13
ILE A 104
TYR A 108
 None
GSH  A 504 (-4.7A)
None
GSH  A 504 (-3.7A)
None
None
 0.53A 11gsB-1lbkA:
36.1		 11gsB-1lbkA:
97.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mty METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylococcus
capsulatus) 		PF02332
(Phenol_Hydrox) 		4 GLY B 131
ARG D  18
ILE B 203
GLY B 126
 None
 0.85A 11gsB-1mtyB:
undetectable		 11gsB-1mtyB:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd2 HEMATOPOIETIC
PROSTAGLANDIN D
SYNTHASE

(Rattus
norvegicus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR 1   8
PHE 1   9
GLY 1  13
ARG 1  14
 GSH  1 301 (-4.8A)
None
None
GSH  1 301 (-3.4A)
 0.48A 11gsB-1pd21:
23.9		 11gsB-1pd21:
28.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)

(Salmonella
enterica) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 105
PHE A  60
ILE A 189
GLY A 165
 None
 0.83A 11gsB-1r2fA:
undetectable		 11gsB-1r2fA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjr BX1

(Zea mays) 		PF00290
(Trp_syntA) 		5 TYR A 255
PHE A 253
GLY A 291
ILE A 313
GLY A 310
 None
 1.23A 11gsB-1tjrA:
undetectable		 11gsB-1tjrA:
22.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
PHE A   8
GLY A  12
TYR A 106
GLY A 204
 None
GSH  A1001 (-4.8A)
None
None
None
 0.39A 11gsB-1tu7A:
30.9		 11gsB-1tu7A:
42.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 106
GLY A 204
TYR A   7
GLY A  12
 None
 0.71A 11gsB-1tu7A:
30.9		 11gsB-1tu7A:
42.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3i GLUTATHIONE
S-TRANSFERASE 28 KDA

(Schistosoma
mansoni) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  10
PHE A  11
GLY A  15
ARG A  16
 None
None
None
GSH  A 301 (-4.2A)
 0.66A 11gsB-1u3iA:
23.6		 11gsB-1u3iA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT

(Mycobacterium
tuberculosis) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 110
PHE A  65
ILE A 194
GLY A 170
 None
 0.81A 11gsB-1uzrA:
undetectable		 11gsB-1uzrA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   8
PHE A   9
GLY A  13
ARG A  14
 None
O16  A3201 (-3.0A)
O16  A3201 ( 3.7A)
O16  A3201 ( 3.8A)
 0.38A 11gsB-1v40A:
24.5		 11gsB-1v40A:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8q U8 SNORNA-BINDING
PROTEIN X29

(Xenopus laevis) 		PF00293
(NUDIX) 		5 PHE A 172
ARG A 156
ILE A  54
TYR A 160
GLY A 168
 None
 1.35A 11gsB-2a8qA:
undetectable		 11gsB-2a8qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2apj PUTATIVE ESTERASE

(Arabidopsis
thaliana) 		PF03629
(SASA) 		4 GLY A 150
ARG A 146
ILE A 152
GLY A 114
 None
 0.85A 11gsB-2apjA:
undetectable		 11gsB-2apjA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bco SUCCINYLGLUTAMATE
DESUCCINYLASE

(Vibrio
parahaemolyticus) 		PF04952
(AstE_AspA) 		4 GLY A 160
ARG A 159
ILE A 158
GLY A 221
 None
 0.86A 11gsB-2bcoA:
undetectable		 11gsB-2bcoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cdq ASPARTOKINASE

(Arabidopsis
thaliana) 		PF00696
(AA_kinase) 		4 PHE A 182
GLY A 217
ILE A 177
GLY A 185
 None
 0.81A 11gsB-2cdqA:
undetectable		 11gsB-2cdqA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dnm SRP46 SPLICING
FACTOR

(Homo sapiens) 		PF00076
(RRM_1) 		4 PHE A  34
GLY A  41
ARG A  61
GLY A  38
 None
 0.86A 11gsB-2dnmA:
undetectable		 11gsB-2dnmA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2edy RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE F

(Homo sapiens) 		PF00041
(fn3) 		4 GLY A  39
ARG A  37
ILE A  41
GLY A   7
 None
 0.78A 11gsB-2edyA:
undetectable		 11gsB-2edyA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egu CYSTEINE SYNTHASE

(Geobacillus
kaustophilus) 		PF00291
(PALP) 		4 TYR A 304
GLY A 263
ILE A 271
GLY A 260
 None
 0.80A 11gsB-2eguA:
undetectable		 11gsB-2eguA:
20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fhe GLUTATHIONE
S-TRANSFERASE

(Fasciola
hepatica) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   6
GLY A  11
TYR A 110
GLY A 204
 None
 0.47A 11gsB-2fheA:
25.4		 11gsB-2fheA:
31.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fhe GLUTATHIONE
S-TRANSFERASE

(Fasciola
hepatica) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 110
GLY A 204
TYR A   6
GLY A  11
 None
 0.76A 11gsB-2fheA:
25.4		 11gsB-2fheA:
31.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
GLY A  12
ARG A  13
TYR A 106
GLY A 203
 GTS  A 208 (-4.5A)
GTS  A 208 (-4.7A)
None
GTS  A 208 (-4.0A)
None
None
 0.20A 11gsB-2gsrA:
35.4		 11gsB-2gsrA:
82.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 106
GLY A 203
TYR A   7
GLY A  12
 None
None
GTS  A 208 (-4.5A)
None
 0.61A 11gsB-2gsrA:
35.4		 11gsB-2gsrA:
82.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnl GLUTATHIONE
S-TRANSFERASE 1

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A  32
PHE A  33
GLY A  37
ARG A  38
ILE A 127
 None
None
None
GSH  A 501 (-4.3A)
None
 0.62A 11gsB-2hnlA:
25.5		 11gsB-2hnlA:
28.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j8x URACIL-DNA
GLYCOSYLASE

(Human
gammaherpesvirus
4) 		PF03167
(UDG) 		4 TYR A  93
ILE A 118
TYR A 119
GLY A 135
 None
 0.83A 11gsB-2j8xA:
undetectable		 11gsB-2j8xA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kom PARTITIONING
DEFECTIVE 3 HOMOLOG

(Homo sapiens) 		PF00595
(PDZ) 		4 PHE A 473
GLY A 503
ARG A 504
GLY A 497
 None
 0.86A 11gsB-2komA:
undetectable		 11gsB-2komA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lj8 COFILIN/ACTIN
DEPOLYMERIZING
FACTOR, PUTATIVE

(Trypanosoma
brucei) 		PF00241
(Cofilin_ADF) 		4 PHE A  57
ILE A  36
TYR A  34
GLY A  54
 None
 0.84A 11gsB-2lj8A:
undetectable		 11gsB-2lj8A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3e DIAMINOPIMELATE
DECARBOXYLASE

(Aquifex
aeolicus) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 TYR A  51
ILE A 212
TYR A 215
GLY A 243
 None
 0.86A 11gsB-2p3eA:
undetectable		 11gsB-2p3eA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wdu GLUTATHIONE
TRANSFERASE SIGMA
CLASS

(Fasciola
hepatica) 		PF14497
(GST_C_3) 		4 TYR A  10
PHE A  11
GLY A  15
ARG A  16
 DMS  A1214 ( 4.3A)
GSH  A 301 (-4.4A)
DMS  A1214 (-3.0A)
GDS  A 300 ( 4.1A)
 0.80A 11gsB-2wduA:
24.4		 11gsB-2wduA:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk8 CAI-1 AUTOINDUCER
SYNTHASE

(Vibrio cholerae) 		PF00155
(Aminotran_1_2) 		4 GLY A 196
ILE A 170
TYR A 127
GLY A 166
 None
 0.86A 11gsB-2wk8A:
undetectable		 11gsB-2wk8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wkn FORMAMIDASE

(Delftia
acidovorans) 		PF03069
(FmdA_AmdA) 		4 GLY A 256
ILE A 260
TYR A 328
GLY A 360
 None
 0.75A 11gsB-2wknA:
undetectable		 11gsB-2wknA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
SULFUR RELAY
PROTEIN,
TUSE/DSRC/DSVC
FAMILY

(Desulfomicrobium
norvegicum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
PF04358
(DsrC) 		4 GLY C  89
ILE C  80
TYR C  81
GLY A  77
 None
 0.84A 11gsB-2xsjC:
undetectable		 11gsB-2xsjC:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zp2 KINASE A INHIBITOR

(Bacillus
subtilis) 		PF02682
(CT_C_D) 		4 TYR A 142
PHE A 152
GLY A 154
GLY A 185
 None
 0.80A 11gsB-2zp2A:
undetectable		 11gsB-2zp2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqq METHYLGLUTACONYL-COA
HYDRATASE

(Homo sapiens) 		PF00378
(ECH_1) 		4 GLY A 220
ARG A 223
ILE A 165
GLY A 185
 None
 0.75A 11gsB-2zqqA:
undetectable		 11gsB-2zqqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ail 303AA LONG
HYPOTHETICAL
ESTERASE

(Sulfurisphaera
tokodaii) 		PF07859
(Abhydrolase_3) 		4 GLY A 285
ILE A 238
TYR A 177
GLY A 274
 None
 0.78A 11gsB-3ailA:
undetectable		 11gsB-3ailA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cru GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME

(Schistosoma
japonicum) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
GLY A  12
TYR A 111
GLY A 205
 None
 0.56A 11gsB-3cruA:
26.0		 11gsB-3cruA:
29.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cru GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME

(Schistosoma
japonicum) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 111
GLY A 205
TYR A   7
GLY A  12
 None
 0.69A 11gsB-3cruA:
26.0		 11gsB-3cruA:
29.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC

(Bordetella
parapertussis) 		no annotation 4 TYR A  98
PHE A 150
GLY A  59
GLY A 143
 None
None
SO4  A 306 (-3.2A)
None
 0.70A 11gsB-3d0kA:
undetectable		 11gsB-3d0kA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC

(Bordetella
parapertussis) 		no annotation 4 TYR A  98
PHE A 150
GLY A  59
GLY A 148
 None
None
SO4  A 306 (-3.2A)
None
 0.84A 11gsB-3d0kA:
undetectable		 11gsB-3d0kA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e73 LANC-LIKE PROTEIN 1

(Homo sapiens) 		PF05147
(LANC_like) 		4 PHE A 199
GLY A 190
ILE A 224
TYR A 225
 None
 0.76A 11gsB-3e73A:
2.7		 11gsB-3e73A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fij LIN1909 PROTEIN

(Listeria
innocua) 		PF07722
(Peptidase_C26) 		4 TYR A 212
GLY A 214
ILE A 182
GLY A 117
 None
 0.84A 11gsB-3fijA:
undetectable		 11gsB-3fijA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftb HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Clostridium
acetobutylicum) 		PF00155
(Aminotran_1_2) 		4 PHE A 186
ILE A  91
TYR A 111
GLY A 151
 None
 0.79A 11gsB-3ftbA:
undetectable		 11gsB-3ftbA:
18.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gtu GLUTATHIONE
S-TRANSFERASE

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 TYR B  10
GLY B  15
ILE B 115
TYR B 119
 None
 0.31A 11gsB-3gtuB:
27.0		 11gsB-3gtuB:
32.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i83 2-DEHYDROPANTOATE
2-REDUCTASE

(Methylococcus
capsulatus) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		5 PHE A 127
GLY A 129
ILE A  11
TYR A  15
GLY A 144
 None
 1.19A 11gsB-3i83A:
undetectable		 11gsB-3i83A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibs CONSERVED
HYPOTHETICAL PROTEIN
BATB

(Bacteroides
thetaiotaomicron) 		PF00092
(VWA) 		4 TYR A 186
GLY A 140
ARG A 188
GLY A 115
 None
 0.53A 11gsB-3ibsA:
undetectable		 11gsB-3ibsA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igx TRANSALDOLASE

(Francisella
tularensis) 		PF00923
(TAL_FSA) 		4 TYR A 217
PHE A 222
ILE A 143
GLY A 174
 None
 0.64A 11gsB-3igxA:
undetectable		 11gsB-3igxA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9d ALDEHYDE
DEHYDROGENASE

(Listeria
monocytogenes) 		PF00171
(Aldedh) 		4 TYR A 208
GLY A 216
ILE A 434
GLY A 423
 None
 0.82A 11gsB-3k9dA:
undetectable		 11gsB-3k9dA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lhx KETODEOXYGLUCONOKINA
SE

(Shigella
flexneri) 		PF00294
(PfkB) 		5 GLY A 372
ARG A 171
ILE A 163
TYR A 161
GLY A 100
 None
 1.39A 11gsB-3lhxA:
undetectable		 11gsB-3lhxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica) 		PF00923
(TAL_FSA) 		4 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.76A 11gsB-3m16A:
undetectable		 11gsB-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F

(Corynebacterium
ammoniagenes) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.82A 11gsB-3mjoA:
undetectable		 11gsB-3mjoA:
18.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
GLY A  12
ARG A  13
TYR A 108
GLY A 205
 None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
 0.30A 11gsB-3o76A:
36.4		 11gsB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 108
GLY A 205
TYR A   7
GLY A  12
 GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
None
None
 0.70A 11gsB-3o76A:
36.4		 11gsB-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE

(Synechocystis
sp. PCC 6803) 		no annotation 4 PHE B 791
GLY B 782
ILE B 778
GLY B 804
 None
 0.81A 11gsB-3ohwB:
undetectable		 11gsB-3ohwB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohw PHYCOBILISOME LCM
CORE-MEMBRANE LINKER
POLYPEPTIDE

(Synechocystis
sp. PCC 6803) 		no annotation 4 PHE B 834
GLY B 782
ILE B 778
GLY B 836
 None
 0.87A 11gsB-3ohwB:
undetectable		 11gsB-3ohwB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		PF01547
(SBP_bac_1) 		4 PHE A 238
GLY A 241
ILE A 461
TYR A 460
 None
 0.64A 11gsB-3ombA:
undetectable		 11gsB-3ombA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u5u RAUCAFFRICINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 TYR A 257
PHE A 261
GLY A 267
GLY A 264
 None
 0.74A 11gsB-3u5uA:
undetectable		 11gsB-3u5uA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrc GALLATE DIOXYGENASE

(Sphingomonas
paucimobilis) 		PF02900
(LigB)
PF07746
(LigA) 		4 TYR A  54
GLY A 125
ILE A  16
GLY A 188
 None
 0.82A 11gsB-3wrcA:
undetectable		 11gsB-3wrcA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq4 RIBONUCLEASE J 1

(Bacillus
subtilis) 		PF00753
(Lactamase_B)
PF07521
(RMMBL) 		4 TYR A  25
GLY A  16
ILE A  20
GLY A  39
 None
 0.75A 11gsB-3zq4A:
undetectable		 11gsB-3zq4A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aio LIMIT DEXTRINASE

(Hordeum vulgare) 		PF02922
(CBM_48)
PF11852
(DUF3372) 		4 PHE A 539
ILE A 254
TYR A 506
GLY A 537
 None
 0.81A 11gsB-4aioA:
undetectable		 11gsB-4aioA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4atw ALPHA-L-ARABINOFURAN
OSIDASE DOMAIN
PROTEIN

(Thermotoga
maritima) 		PF06964
(Alpha-L-AF_C) 		4 TYR A 412
GLY A 307
ILE A 353
GLY A 302
 None
 0.80A 11gsB-4atwA:
undetectable		 11gsB-4atwA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvq GLUTAMATE-PYRUVATE
AMINOTRANSFERASE
ALAA

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 PHE A 235
GLY A 237
ILE A  81
TYR A  85
 None
 0.79A 11gsB-4cvqA:
undetectable		 11gsB-4cvqA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4di1 ENOYL-COA HYDRATASE
ECHA17

(Mycobacterium
marinum) 		PF00378
(ECH_1) 		4 GLY A 142
ARG A 145
ILE A  87
GLY A 107
 None
 0.76A 11gsB-4di1A:
undetectable		 11gsB-4di1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dns FAD-LINKED
OXIDOREDUCTASE BG60

(Cynodon
dactylon) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 PHE A 161
GLY A 208
ARG A 207
GLY A 165
 None
None
None
FAD  A 501 (-3.6A)
 0.86A 11gsB-4dnsA:
undetectable		 11gsB-4dnsA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 PHE A 394
ARG A 412
ILE A 580
TYR A 582
 None
 0.84A 11gsB-4ecnA:
undetectable		 11gsB-4ecnA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l5o PUTATIVE GLUTATHIONE
TRANSFERASE

(Clonorchis
sinensis) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
GLY A  12
TYR A 111
GLY A 205
 None
 0.80A 11gsB-4l5oA:
25.1		 11gsB-4l5oA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		4 TYR A 147
ILE A 173
TYR A 174
GLY A 190
 None
 0.86A 11gsB-4lylA:
undetectable		 11gsB-4lylA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mou ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Paenarthrobacter
aurescens) 		PF00378
(ECH_1) 		4 TYR A 151
GLY A 120
ILE A 140
GLY A 175
 None
 0.84A 11gsB-4mouA:
undetectable		 11gsB-4mouA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nte DEPH

(Chromobacterium
violaceum) 		PF07992
(Pyr_redox_2) 		4 GLY A  52
ARG A  56
ILE A  61
GLY A  49
 None
None
None
NA  A 303 (-4.5A)
 0.76A 11gsB-4nteA:
undetectable		 11gsB-4nteA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzk UNCHARACTERIZED
PROTEIN

([Eubacterium]
siraeum) 		PF14286
(DHHW) 		5 TYR A 108
PHE A 367
GLY A 111
ILE A 164
GLY A 371
 None
 1.20A 11gsB-4nzkA:
undetectable		 11gsB-4nzkA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5p UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF09994
(DUF2235) 		4 PHE A 234
GLY A 116
ILE A 135
GLY A 237
 None
 0.85A 11gsB-4o5pA:
undetectable		 11gsB-4o5pA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqj PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 TYR A 227
PHE A 235
GLY A 239
GLY A 250
 None
 0.70A 11gsB-4oqjA:
undetectable		 11gsB-4oqjA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9n CARBOXYLESTERASE

(Sulfolobus
shibatae) 		PF07859
(Abhydrolase_3) 		4 GLY A 286
ILE A 239
TYR A 177
GLY A 275
 None
 0.86A 11gsB-4p9nA:
undetectable		 11gsB-4p9nA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pue ENDO-1,4-BETA-XYLANA
SE

(Geobacillus
stearothermophilus) 		PF00331
(Glyco_hydro_10) 		4 PHE A 360
ILE A 284
TYR A 281
GLY A 363
 None
 0.67A 11gsB-4pueA:
undetectable		 11gsB-4pueA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5n GLUTHATIONE
S-TRANSFERASE BLO T
8 ISOFORM

(Blomia
tropicalis) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   8
GLY A  13
ILE A 116
TYR A 120
 None
None
GSH  A 402 ( 4.5A)
GSH  A 402 (-3.9A)
 0.81A 11gsB-4q5nA:
25.7		 11gsB-4q5nA:
27.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q5q GLUTATHIONE
S-TRANSFERASE

(Dermatophagoides
pteronyssinus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   8
GLY A  13
ILE A 113
TYR A 117
 None
 0.77A 11gsB-4q5qA:
25.8		 11gsB-4q5qA:
30.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wr4 GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME

(Schistosoma
japonicum) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   6
GLY A  11
TYR A 110
GLY A 204
 None
 0.68A 11gsB-4wr4A:
26.0		 11gsB-4wr4A:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wr4 GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME

(Schistosoma
japonicum) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 110
GLY A 204
TYR A   6
GLY A  11
 None
 0.81A 11gsB-4wr4A:
26.0		 11gsB-4wr4A:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE

(Caulobacter
vibrioides) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 GLY A 187
ILE A 327
TYR A 328
GLY A 181
 None
 0.84A 11gsB-5a05A:
undetectable		 11gsB-5a05A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5u PROLYL 4-HYDROXYLASE

(Paramecium
bursaria
Chlorella virus
1) 		PF13640
(2OG-FeII_Oxy_3) 		4 PHE A 188
GLY A 223
ILE A 233
TYR A 174
 None
UNX  A 302 ( 3.5A)
UNX  A 303 ( 4.4A)
None
 0.82A 11gsB-5c5uA:
undetectable		 11gsB-5c5uA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1i CYCLIC
NUCLEOTIDE-BINDING
PROTEIN

(Brucella
abortus) 		PF00027
(cNMP_binding) 		4 PHE A  19
GLY A  14
ILE A  81
GLY A  11
 None
 0.76A 11gsB-5d1iA:
undetectable		 11gsB-5d1iA:
21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
PHE A   8
GLY A  12
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
None
 0.37A 11gsB-5d73A:
31.0		 11gsB-5d73A:
42.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 106
GLY A 204
TYR A   7
GLY A  12
 None
 0.65A 11gsB-5d73A:
31.0		 11gsB-5d73A:
42.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)

(Aspergillus
fumigatus) 		PF00982
(Glyco_transf_20) 		4 PHE A  87
GLY A  62
ILE A  23
GLY A  59
 None
 0.70A 11gsB-5hvmA:
undetectable		 11gsB-5hvmA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 TYR B 196
PHE B  76
ILE B 249
GLY B  80
 None
 0.83A 11gsB-5kohB:
undetectable		 11gsB-5kohB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnt PYRIDOXAL
5'-PHOSPHATE
SYNTHASE SUBUNIT
PDX1.1

(Arabidopsis
thaliana) 		PF01680
(SOR_SNZ) 		4 PHE A 250
GLY A 230
ARG A 166
GLY A 252
 KPR  A 401 (-4.2A)
KPR  A 401 (-3.4A)
None
KPR  A 401 (-3.4A)
 0.84A 11gsB-5lntA:
undetectable		 11gsB-5lntA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT B
TUNGSTEN-CONTAINING
FORMYLMETHANOFURAN
DEHYDROGENASE 2
SUBUNIT C

(Methanothermobacter
sp. CaT2;
Methanothermobacter
wolfeii) 		PF00384
(Molybdopterin)
PF01493
(GXGXG) 		4 TYR B 207
GLY C 202
ILE C 251
GLY C 221
 None
 0.77A 11gsB-5t5iB:
undetectable		 11gsB-5t5iB:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vn4 ADENINE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE

(Trypanosoma
brucei) 		PF00156
(Pribosyltran) 		4 TYR A  10
PHE A 200
GLY A 177
GLY A 174
 None
 0.79A 11gsB-5vn4A:
undetectable		 11gsB-5vn4A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhu FERREDOXIN--NADP
REDUCTASE

(Bacillus
subtilis) 		no annotation 4 PHE A 302
GLY A 305
ILE A  12
GLY A 286
 None
None
None
FAD  A1000 (-3.2A)
 0.85A 11gsB-5xhuA:
undetectable		 11gsB-5xhuA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cf8 LYTIC
TRANSGLYCOSYLASE

(Campylobacter
jejuni) 		no annotation 4 TYR A 461
PHE A 458
GLY A 503
ILE A 282
 None
 0.80A 11gsB-6cf8A:
undetectable		 11gsB-6cf8A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cv0 SPIKE GLYCOPROTEIN

(Avian
coronavirus) 		no annotation 4 GLY A 560
ILE A 562
TYR A 525
GLY A 507
 None
 0.86A 11gsB-6cv0A:
undetectable		 11gsB-6cv0A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fth EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		no annotation 4 PHE A 216
GLY A 219
ILE A 439
TYR A 438
 None
 0.73A 11gsB-6fthA:
undetectable		 11gsB-6fthA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g21 PROBABLE FERULOYL
ESTERASE B-2

(Aspergillus
oryzae) 		no annotation 4 PHE A 469
GLY A 427
ILE A 416
GLY A 424
 None
 0.80A 11gsB-6g21A:
undetectable		 11gsB-6g21A:
15.24