SIMILAR PATTERNS OF AMINO ACIDS FOR 11GS_A_EAAA211_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bud PROTEIN (ACUTOLYSIN
A)


(Deinagkistrodon
acutus)
PF01421
(Reprolysin)
4 VAL A 150
ARG A 187
ILE A  49
TYR A  44
None
0.78A 11gsA-1budA:
undetectable
11gsA-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3l PROTEIN ARGININE
METHYLTRANSFERASE
PRMT3


(Rattus
norvegicus)
PF06325
(PrmA)
4 TYR A 330
PHE A 334
ILE A 226
TYR A 221
None
None
None
SAH  A 529 (-3.5A)
0.78A 11gsA-1f3lA:
undetectable
11gsA-1f3lA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f7u ARGINYL-TRNA
SYNTHETASE


(Saccharomyces
cerevisiae)
PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1)
4 TYR A 471
VAL A 405
ILE A 167
GLY A 161
None
0.96A 11gsA-1f7uA:
2.5
11gsA-1f7uA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flz URACIL-DNA
GLYCOSYLASE


(Escherichia
coli)
PF03167
(UDG)
4 TYR A  66
VAL A  79
TYR A  93
GLY A 109
URA  A 230 (-3.2A)
None
None
None
0.92A 11gsA-1flzA:
undetectable
11gsA-1flzA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1huj INORGANIC
PYROPHOSPHATASE


(Saccharomyces
cerevisiae)
PF00719
(Pyrophosphatase)
4 TYR A  15
VAL A  17
ILE A  49
GLY A 132
None
0.93A 11gsA-1hujA:
undetectable
11gsA-1hujA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsc ACETOHYDROXY-ACID
SYNTHASE


(Saccharomyces
cerevisiae)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 PHE A 111
VAL A 159
ILE A 182
GLY A 143
None
0.95A 11gsA-1jscA:
0.0
11gsA-1jscA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka9 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE


(Thermus
thermophilus)
PF00117
(GATase)
4 TYR H  10
PHE H  59
VAL H  55
ILE H  81
None
0.96A 11gsA-1ka9H:
undetectable
11gsA-1ka9H:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
None
0.76A 11gsA-1kgpA:
undetectable
11gsA-1kgpA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1j HEAT SHOCK PROTEASE
HTRA


(Thermotoga
maritima)
PF13365
(Trypsin_2)
4 PHE A  84
VAL A  40
ILE A 158
GLY A 161
None
0.95A 11gsA-1l1jA:
undetectable
11gsA-1l1jA:
24.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)


(Homo sapiens)
PF02798
(GST_N)
PF14497
(GST_C_3)
6 TYR A   7
PHE A   8
VAL A  10
ARG A  13
ILE A 104
TYR A 108
None
GSH  A 504 (-4.7A)
None
GSH  A 504 (-3.7A)
None
None
0.59A 11gsA-1lbkA:
36.1
11gsA-1lbkA:
97.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p9b ADENYLOSUCCINATE
SYNTHETASE


(Plasmodium
falciparum)
PF00709
(Adenylsucc_synt)
4 PHE A  46
ILE A 145
TYR A 149
GLY A  84
None
IMO  A1601 ( 4.6A)
None
None
0.89A 11gsA-1p9bA:
undetectable
11gsA-1p9bA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz3 ALPHA-L-ARABINOFURAN
OSIDASE


(Geobacillus
stearothermophilus)
PF06964
(Alpha-L-AF_C)
4 VAL A 413
ILE A  23
TYR A  24
GLY A 383
None
0.81A 11gsA-1pz3A:
undetectable
11gsA-1pz3A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qc5 PROTEIN (ALPHA1
BETA1 INTEGRIN)


(Homo sapiens)
PF00092
(VWA)
4 VAL B 338
ARG B 466
ILE B 456
GLY B 415
None
0.92A 11gsA-1qc5B:
undetectable
11gsA-1qc5B:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
4 TYR A 105
PHE A  60
ILE A 189
GLY A 165
None
0.83A 11gsA-1r2fA:
undetectable
11gsA-1r2fA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfj 3-DEHYDROQUINATE
DEHYDRATASE


(Staphylococcus
aureus)
PF01487
(DHquinase_I)
4 VAL A   4
ARG A 202
ILE A 192
GLY A 210
None
DHK  A 239 (-2.6A)
DHK  A 239 ( 4.2A)
None
0.96A 11gsA-1sfjA:
undetectable
11gsA-1sfjA:
22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2


(Onchocerca
volvulus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   7
PHE A   8
TYR A 106
GLY A 204
None
GSH  A1001 (-4.8A)
None
None
0.40A 11gsA-1tu7A:
31.0
11gsA-1tu7A:
42.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT


(Mycobacterium
tuberculosis)
PF00268
(Ribonuc_red_sm)
4 TYR A 110
PHE A  65
ILE A 194
GLY A 170
None
0.81A 11gsA-1uzrA:
undetectable
11gsA-1uzrA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE


(Pyrobaculum
aerophilum)
PF09171
(AGOG)
4 PHE A  76
VAL A  38
ILE A 148
GLY A  47
None
0.79A 11gsA-1xqpA:
undetectable
11gsA-1xqpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE
SUBUNIT C2
PARTICULATE METHANE
MONOOXYGENASE, A
SUBUNIT


(Methylococcus
capsulatus)
PF02461
(AMO)
PF04896
(AmoC)
4 TYR C 146
PHE B  31
VAL B  34
GLY B  95
None
0.93A 11gsA-1yewC:
undetectable
11gsA-1yewC:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8q U8 SNORNA-BINDING
PROTEIN X29


(Xenopus laevis)
PF00293
(NUDIX)
5 PHE A 172
ARG A 156
ILE A  54
TYR A 160
GLY A 168
None
1.35A 11gsA-2a8qA:
undetectable
11gsA-2a8qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2x INTEGRIN ALPHA-1

(Rattus
norvegicus)
PF00092
(VWA)
4 VAL A 152
ARG A 280
ILE A 270
GLY A 229
None
0.87A 11gsA-2b2xA:
undetectable
11gsA-2b2xA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcu PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 3


(Arabidopsis
thaliana)
PF00753
(Lactamase_B)
4 TYR A  29
PHE A 150
ILE A 157
GLY A 152
None
None
EDO  A2003 (-4.9A)
None
0.93A 11gsA-2gcuA:
undetectable
11gsA-2gcuA:
23.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE


(Sus scrofa)
PF02798
(GST_N)
PF14497
(GST_C_3)
6 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TYR A 106
GLY A 203
GTS  A 208 (-4.5A)
GTS  A 208 (-4.7A)
None
GTS  A 208 (-4.0A)
None
None
0.22A 11gsA-2gsrA:
35.4
11gsA-2gsrA:
82.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gup ROK FAMILY PROTEIN

(Streptococcus
pneumoniae)
PF00480
(ROK)
4 TYR A  78
VAL A  76
ILE A  30
GLY A   9
None
0.81A 11gsA-2gupA:
undetectable
11gsA-2gupA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnl GLUTATHIONE
S-TRANSFERASE 1


(Onchocerca
volvulus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A  32
PHE A  33
ARG A  38
ILE A 127
None
None
GSH  A 501 (-4.3A)
None
0.61A 11gsA-2hnlA:
25.5
11gsA-2hnlA:
28.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hp3 IDS-EPIMERASE

(Agrobacterium
tumefaciens)
PF03972
(MmgE_PrpD)
4 PHE A 371
VAL A 306
ILE A 393
GLY A 373
None
None
None
UNX  A1212 ( 3.6A)
0.96A 11gsA-2hp3A:
undetectable
11gsA-2hp3A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE


(Streptomyces
clavuligerus)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 TYR A 561
PHE A 412
ILE A 460
GLY A 411
TPP  A 600 ( 4.2A)
None
None
TPP  A 600 (-3.6A)
0.88A 11gsA-2ihtA:
undetectable
11gsA-2ihtA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j8x URACIL-DNA
GLYCOSYLASE


(Human
gammaherpesvirus
4)
PF03167
(UDG)
5 TYR A  93
VAL A 105
ILE A 118
TYR A 119
GLY A 135
None
1.05A 11gsA-2j8xA:
undetectable
11gsA-2j8xA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhq URACIL
DNA-GLYCOSYLASE


(Vibrio cholerae)
PF03167
(UDG)
5 TYR A  66
VAL A  79
ILE A  92
TYR A  93
GLY A 109
None
1.01A 11gsA-2jhqA:
undetectable
11gsA-2jhqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lj8 COFILIN/ACTIN
DEPOLYMERIZING
FACTOR, PUTATIVE


(Trypanosoma
brucei)
PF00241
(Cofilin_ADF)
4 PHE A  57
ILE A  36
TYR A  34
GLY A  54
None
0.84A 11gsA-2lj8A:
undetectable
11gsA-2lj8A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2msk NITROGEN REGULATION
PROTEIN NR(I)


(Salmonella
enterica)
PF00072
(Response_reg)
4 PHE A  33
VAL A   9
ILE A  69
GLY A  36
None
0.92A 11gsA-2mskA:
undetectable
11gsA-2mskA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p14 HETERODIMERIC
RESTRICTION
ENDONUCLEASE
R.BSPD6I SMALL
SUBUNIT


(Bacillus sp. D6)
PF09491
(RE_AlwI)
4 TYR A   8
VAL A 135
ILE A  72
GLY A 110
None
0.85A 11gsA-2p14A:
undetectable
11gsA-2p14A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3e DIAMINOPIMELATE
DECARBOXYLASE


(Aquifex
aeolicus)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
4 TYR A  51
ILE A 212
TYR A 215
GLY A 243
None
0.85A 11gsA-2p3eA:
undetectable
11gsA-2p3eA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q9u A-TYPE FLAVOPROTEIN

(Giardia
intestinalis)
no annotation 4 PHE A  30
VAL A  27
ILE A  22
GLY A  38
NO3  A 501 (-4.7A)
None
None
None
0.93A 11gsA-2q9uA:
undetectable
11gsA-2q9uA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qiw PEP PHOSPHONOMUTASE

(Corynebacterium
glutamicum)
PF13714
(PEP_mutase)
4 VAL A  86
ILE A 132
TYR A 131
GLY A  89
None
0.94A 11gsA-2qiwA:
undetectable
11gsA-2qiwA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qru UNCHARACTERIZED
PROTEIN


(Enterococcus
faecalis)
PF07859
(Abhydrolase_3)
4 TYR A 131
ILE A  75
TYR A  64
GLY A  33
None
None
None
PO4  A 273 ( 3.7A)
0.93A 11gsA-2qruA:
undetectable
11gsA-2qruA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c26 PUTATIVE
ACETYLTRANSFERASE
TA0821


(Thermoplasma
acidophilum)
PF00583
(Acetyltransf_1)
4 VAL A  63
ARG A  90
ILE A  52
GLY A  10
None
NO3  A 266 (-3.9A)
None
None
0.97A 11gsA-3c26A:
undetectable
11gsA-3c26A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM


(Lactococcus
lactis)
PF03610
(EIIA-man)
4 PHE C  88
VAL C  90
ILE C   7
GLY C  95
None
0.92A 11gsA-3cr3C:
undetectable
11gsA-3cr3C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE


(Leishmania
naiffi)
PF03167
(UDG)
5 TYR A 208
VAL A 221
ILE A 234
TYR A 235
GLY A 251
URB  A 401 ( 3.3A)
None
None
None
None
1.00A 11gsA-3cxmA:
undetectable
11gsA-3cxmA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE


(Burkholderia
pseudomallei)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 TYR A 373
VAL A 369
ILE A 210
GLY A 215
None
0.76A 11gsA-3d6bA:
1.5
11gsA-3d6bA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftb HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE


(Clostridium
acetobutylicum)
PF00155
(Aminotran_1_2)
4 PHE A 186
ILE A  91
TYR A 111
GLY A 151
None
0.79A 11gsA-3ftbA:
undetectable
11gsA-3ftbA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2t BASEPLATE STRUCTURAL
PROTEIN GP6


(Escherichia
virus T4)
no annotation 4 PHE A 517
VAL A 538
ILE A 592
GLY A 556
None
0.86A 11gsA-3h2tA:
undetectable
11gsA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i83 2-DEHYDROPANTOATE
2-REDUCTASE


(Methylococcus
capsulatus)
PF02558
(ApbA)
PF08546
(ApbA_C)
4 PHE A 127
ILE A  11
TYR A  15
GLY A 144
None
0.86A 11gsA-3i83A:
undetectable
11gsA-3i83A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igx TRANSALDOLASE

(Francisella
tularensis)
PF00923
(TAL_FSA)
4 TYR A 217
PHE A 222
ILE A 143
GLY A 174
None
0.65A 11gsA-3igxA:
undetectable
11gsA-3igxA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3is6 PUTATIVE PERMEASE
PROTEIN, ABC
TRANSPORTER


(Porphyromonas
gingivalis)
PF12704
(MacB_PCD)
4 TYR A 262
VAL A  84
ILE A 216
GLY A  82
None
0.93A 11gsA-3is6A:
undetectable
11gsA-3is6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isl PURINE CATABOLISM
PROTEIN PUCG


(Bacillus
subtilis)
PF00266
(Aminotran_5)
4 PHE A  99
VAL A 145
ILE A 106
GLY A 100
PLP  A 419 (-3.5A)
None
None
None
0.89A 11gsA-3islA:
undetectable
11gsA-3islA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kc2 UNCHARACTERIZED
PROTEIN YKR070W


(Saccharomyces
cerevisiae)
PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6)
4 TYR A 111
VAL A 107
ILE A  79
GLY A  56
None
0.84A 11gsA-3kc2A:
undetectable
11gsA-3kc2A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT


(Acetoanaerobium
sticklandii)
PF02310
(B12-binding)
PF09043
(Lys-AminoMut_A)
PF16554
(OAM_dimer)
4 PHE A  87
VAL A 130
ILE A 105
TYR A 157
None
0.85A 11gsA-3koyA:
undetectable
11gsA-3koyA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kux PUTATIVE
OXIDOREDUCTASE


(Yersinia pestis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 PHE A 250
ARG A 237
TYR A 247
GLY A 277
None
0.88A 11gsA-3kuxA:
undetectable
11gsA-3kuxA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica)
PF00923
(TAL_FSA)
4 TYR A 220
PHE A 225
ILE A 147
GLY A 178
None
0.77A 11gsA-3m16A:
undetectable
11gsA-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
None
0.82A 11gsA-3mjoA:
undetectable
11gsA-3mjoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 4 TYR B 105
PHE B  60
ILE B 189
GLY B 165
None
0.96A 11gsA-3n3bB:
undetectable
11gsA-3n3bB:
19.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1


(Mus musculus)
PF02798
(GST_N)
PF14497
(GST_C_3)
6 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.31A 11gsA-3o76A:
36.5
11gsA-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvz UDP-N-ACETYLGLUCOSAM
INE 4,6-DEHYDRATASE


(Aliivibrio
fischeri)
PF02719
(Polysacc_synt_2)
4 TYR A 157
VAL A 113
ILE A  95
TYR A 100
None
None
NAD  A 501 (-3.9A)
None
0.88A 11gsA-3pvzA:
undetectable
11gsA-3pvzA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s88 16F6 - HEAVY CHAIN
ENVELOPE
GLYCOPROTEIN


(Mus musculus;
Sudan
ebolavirus)
PF01611
(Filo_glycop)
PF07654
(C1-set)
PF07686
(V-set)
4 TYR H  31
VAL I  45
ILE I  48
GLY I  36
None
0.95A 11gsA-3s88H:
undetectable
11gsA-3s88H:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sh5 LG3 PEPTIDE

(Homo sapiens)
PF00054
(Laminin_G_1)
4 PHE A 152
VAL A 144
ILE A 138
GLY A 155
None
0.76A 11gsA-3sh5A:
undetectable
11gsA-3sh5A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t90 GLUCOSE-6-PHOSPHATE
ACETYLTRANSFERASE 1


(Arabidopsis
thaliana)
PF00583
(Acetyltransf_1)
4 PHE A 107
VAL A 104
ILE A  64
GLY A  68
None
0.83A 11gsA-3t90A:
undetectable
11gsA-3t90A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tbj ACTIBIND

(Aspergillus
niger)
PF00445
(Ribonuclease_T2)
4 TYR A 237
VAL A 228
ILE A 145
GLY A 230
None
0.87A 11gsA-3tbjA:
undetectable
11gsA-3tbjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr7 URACIL-DNA
GLYCOSYLASE


(Coxiella
burnetii)
PF03167
(UDG)
4 TYR A  69
VAL A  82
ILE A  95
GLY A 111
None
0.89A 11gsA-3tr7A:
undetectable
11gsA-3tr7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ue9 ADENYLOSUCCINATE
SYNTHETASE


(Burkholderia
thailandensis)
PF00709
(Adenylsucc_synt)
4 PHE A  43
ILE A 143
TYR A 147
GLY A  81
None
0.94A 11gsA-3ue9A:
undetectable
11gsA-3ue9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdj TYPE I PULLULANASE

(Anoxybacillus
sp. LM18-11)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 VAL A 592
ILE A 267
TYR A 225
GLY A 569
None
0.89A 11gsA-3wdjA:
undetectable
11gsA-3wdjA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zoq URACIL-DNA
GLYCOSYLASE


(Bacillus
subtilis)
PF03167
(UDG)
4 TYR A  67
VAL A  80
ILE A  93
GLY A 109
None
0.96A 11gsA-3zoqA:
undetectable
11gsA-3zoqA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aio LIMIT DEXTRINASE

(Hordeum vulgare)
PF02922
(CBM_48)
PF11852
(DUF3372)
4 PHE A 539
ILE A 254
TYR A 506
GLY A 537
None
0.80A 11gsA-4aioA:
undetectable
11gsA-4aioA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni)
no annotation 4 PHE A  27
VAL A  29
TYR A  67
GLY A  65
None
0.82A 11gsA-4bg2A:
undetectable
11gsA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chl PERSULFIDE
DIOXYGENASE ETHE1,
MITOCHONDRIAL


(Homo sapiens)
PF00753
(Lactamase_B)
4 TYR A  38
PHE A 151
ILE A 158
GLY A 153
None
0.94A 11gsA-4chlA:
undetectable
11gsA-4chlA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4con ANAEROBIC
RIBONUCLEOSIDE-TRIPH
OSPHATE REDUCTASE


(Thermotoga
maritima)
PF13597
(NRDD)
4 TYR A 227
ILE A 555
TYR A 584
GLY A 361
None
0.94A 11gsA-4conA:
undetectable
11gsA-4conA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN


(Bacteroides
thetaiotaomicron)
PF14660
(DUF4458)
4 PHE A 394
ARG A 412
ILE A 580
TYR A 582
None
0.83A 11gsA-4ecnA:
undetectable
11gsA-4ecnA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqj HEMAGGLUTININ

(Influenza B
virus)
PF00509
(Hemagglutinin)
4 TYR A 202
VAL A 160
ILE A 243
GLY A 138
None
0.93A 11gsA-4fqjA:
undetectable
11gsA-4fqjA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hdt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE


(Mycolicibacterium
thermoresistibile)
PF16113
(ECH_2)
4 TYR A  92
VAL A 148
ILE A  73
GLY A 116
None
0.82A 11gsA-4hdtA:
undetectable
11gsA-4hdtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN


(Pseudomonas)
PF01804
(Penicil_amidase)
4 TYR B  32
PHE B  31
VAL B  49
ILE B 176
GLJ  B 601 (-4.9A)
None
None
None
0.96A 11gsA-4hstB:
undetectable
11gsA-4hstB:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE


(Gadus morhua)
PF03167
(UDG)
5 TYR A 147
VAL A 160
ILE A 173
TYR A 174
GLY A 190
None
1.02A 11gsA-4lylA:
undetectable
11gsA-4lylA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1b POLYSACCHARIDE
DEACETYLASE


(Bacillus
anthracis)
PF01522
(Polysacc_deac_1)
4 ARG A 132
ILE A 167
TYR A 123
GLY A 117
None
0.93A 11gsA-4m1bA:
undetectable
11gsA-4m1bA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n83 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Streptococcus
sanguinis)
PF00268
(Ribonuc_red_sm)
4 TYR A 104
PHE A  59
ILE A 188
GLY A 164
None
0.89A 11gsA-4n83A:
undetectable
11gsA-4n83A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4na3 POLYKETIDE SYNTHASE
PKSJ


(Bacillus
subtilis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 ARG A 266
ILE A 300
TYR A 295
GLY A 427
None
0.87A 11gsA-4na3A:
undetectable
11gsA-4na3A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE


(Geobacter
sulfurreducens)
PF00171
(Aldedh)
PF01619
(Pro_dh)
4 VAL A 938
ARG A 933
ILE A 943
GLY A 919
EDO  A1104 (-4.7A)
None
None
None
0.96A 11gsA-4nmeA:
undetectable
11gsA-4nmeA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE


(Rhodotorula
mucilaginosa)
PF13561
(adh_short_C2)
4 PHE A  76
VAL A  78
ILE A  33
GLY A  53
None
0.84A 11gsA-4o0lA:
undetectable
11gsA-4o0lA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pue ENDO-1,4-BETA-XYLANA
SE


(Geobacillus
stearothermophilus)
PF00331
(Glyco_hydro_10)
4 PHE A 360
ILE A 284
TYR A 281
GLY A 363
None
0.67A 11gsA-4pueA:
undetectable
11gsA-4pueA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3m 2-DEHYDROPANTOATE
2-REDUCTASE


(Staphylococcus
aureus)
PF02558
(ApbA)
PF08546
(ApbA_C)
4 TYR A  40
VAL A 126
ILE A 117
GLY A  11
None
None
None
NAP  A 500 (-3.1A)
0.85A 11gsA-4s3mA:
undetectable
11gsA-4s3mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA


(Bacillus
subtilis)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 VAL A  23
ILE A  31
TYR A 125
GLY A  48
None
0.88A 11gsA-4tr6A:
undetectable
11gsA-4tr6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqm URACIL-DNA
GLYCOSYLASE


(Deinococcus
radiodurans)
PF03167
(UDG)
5 TYR A  85
VAL A  98
ILE A 111
TYR A 112
GLY A 128
CL  A1245 (-4.3A)
None
None
None
None
1.08A 11gsA-4uqmA:
undetectable
11gsA-4uqmA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1e PECTINESTERASE

(Aspergillus
niger)
PF01095
(Pectinesterase)
4 TYR A  73
VAL A 102
TYR A  67
GLY A  89
None
0.93A 11gsA-5c1eA:
undetectable
11gsA-5c1eA:
20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE


(Wuchereria
bancrofti)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   7
PHE A   8
TYR A 106
GLY A 204
None
GSH  A 301 (-4.9A)
None
None
0.39A 11gsA-5d73A:
31.0
11gsA-5d73A:
42.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dis GTP-BINDING NUCLEAR
PROTEIN RAN


(Homo sapiens)
PF00071
(Ras)
4 TYR B 155
VAL B 124
TYR B 146
GLY B 121
None
0.95A 11gsA-5disB:
undetectable
11gsA-5disB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4y HOMOSERINE
O-ACETYLTRANSFERASE


(Pseudomonas
veronii)
PF00561
(Abhydrolase_1)
4 TYR A 194
PHE A 189
VAL A 200
GLY A 203
None
0.96A 11gsA-5e4yA:
undetectable
11gsA-5e4yA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewo STRUCTURAL PROTEIN

(Mamastrovirus 1)
PF12226
(Astro_capsid_p)
4 TYR A 588
PHE A 582
VAL A 543
GLY A 546
None
0.92A 11gsA-5ewoA:
undetectable
11gsA-5ewoA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE


(Plasmodium
falciparum)
PF00227
(Proteasome)
PF10584
(Proteasome_A_N)
4 TYR F 116
PHE F 128
ILE F  72
GLY F  76
None
0.94A 11gsA-5fmgF:
undetectable
11gsA-5fmgF:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5


(Saccharomyces
cerevisiae)
PF12717
(Cnd1)
4 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.86A 11gsA-5frsA:
undetectable
11gsA-5frsA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2


(Saccharomyces
cerevisiae)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
4 TYR B 859
VAL B 968
ARG B 942
GLY B 947
None
0.84A 11gsA-5ip9B:
undetectable
11gsA-5ip9B:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk7 URACIL-DNA
GLYCOSYLASE


(Homo sapiens)
PF03167
(UDG)
4 VAL D 160
ILE D 173
TYR D 174
GLY D 190
None
0.92A 11gsA-5jk7D:
undetectable
11gsA-5jk7D:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK


(Gluconacetobacter
diazotrophicus)
PF00148
(Oxidored_nitro)
PF11844
(DUF3364)
4 TYR B 196
PHE B  76
ILE B 249
GLY B  80
None
0.83A 11gsA-5kohB:
undetectable
11gsA-5kohB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans)
no annotation 4 TYR B  17
PHE B 130
ILE B 137
GLY B 132
None
0.93A 11gsA-5ve3B:
undetectable
11gsA-5ve3B:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x55 PROBABLE URACIL-DNA
GLYCOSYLASE


(Acanthamoeba
polyphaga
mimivirus)
PF03167
(UDG)
5 TYR A 193
VAL A 211
ILE A 224
TYR A 225
GLY A 241
None
0.95A 11gsA-5x55A:
undetectable
11gsA-5x55A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfa NAD-REDUCING
HYDROGENASE


(Hydrogenophilus
thermoluteolus)
PF00374
(NiFeSe_Hases)
4 TYR D 308
PHE D 244
VAL D 310
GLY D 397
None
0.96A 11gsA-5xfaD:
undetectable
11gsA-5xfaD:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwb 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE


(Colwellia
psychrerythraea)
PF00275
(EPSP_synthase)
4 PHE A 250
VAL A 261
ILE A   9
GLY A 254
None
0.92A 11gsA-5xwbA:
undetectable
11gsA-5xwbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0q UPF0348 PROTEIN
B4417_3650


(Bacillus
subtilis)
no annotation 4 TYR A  72
PHE A  41
VAL A  76
GLY A  45
None
0.88A 11gsA-5y0qA:
undetectable
11gsA-5y0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y37 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Streptococcus
agalactiae)
no annotation 4 VAL A 123
ILE A  17
TYR A 324
GLY A 153
None
NAD  A 401 (-4.3A)
NAD  A 401 (-3.6A)
None
0.92A 11gsA-5y37A:
undetectable
11gsA-5y37A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5k DRAXIN
NETRIN RECEPTOR DCC


(Rattus
norvegicus)
no annotation 4 ARG B 282
ILE A 387
TYR A 398
GLY A 396
None
0.95A 11gsA-5z5kB:
undetectable
11gsA-5z5kB:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER


(Homo sapiens)
no annotation 4 TYR A 452
VAL A 309
ILE A 355
GLY A 314
None
0.97A 11gsA-5zalA:
undetectable
11gsA-5zalA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ap4 DNA POLYMERASE III
SUBUNIT BETA


(Acinetobacter
baumannii)
no annotation 4 VAL A  21
ILE A  29
TYR A 119
GLY A  46
None
0.89A 11gsA-6ap4A:
undetectable
11gsA-6ap4A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gsw MU CLASS GLUTATHIONE
S-TRANSFERASE OF
ISOENZYME 3-3


(Rattus rattus)
PF00043
(GST_C)
PF02798
(GST_N)
4 TYR A   6
VAL A   9
ILE A 111
TYR A 115
None
None
GPS  A 221 (-4.5A)
None
0.89A 11gsA-6gswA:
25.7
11gsA-6gswA:
30.00