SIMILAR PATTERNS OF AMINO ACIDS FOR 11GS_A_EAAA211_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bud | PROTEIN (ACUTOLYSINA) (Deinagkistrodonacutus) |
PF01421(Reprolysin) | 4 | VAL A 150ARG A 187ILE A 49TYR A 44 | None | 0.78A | 11gsA-1budA:undetectable | 11gsA-1budA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f3l | PROTEIN ARGININEMETHYLTRANSFERASEPRMT3 (Rattusnorvegicus) |
PF06325(PrmA) | 4 | TYR A 330PHE A 334ILE A 226TYR A 221 | NoneNoneNoneSAH A 529 (-3.5A) | 0.78A | 11gsA-1f3lA:undetectable | 11gsA-1f3lA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f7u | ARGINYL-TRNASYNTHETASE (Saccharomycescerevisiae) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 4 | TYR A 471VAL A 405ILE A 167GLY A 161 | None | 0.96A | 11gsA-1f7uA:2.5 | 11gsA-1f7uA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flz | URACIL-DNAGLYCOSYLASE (Escherichiacoli) |
PF03167(UDG) | 4 | TYR A 66VAL A 79TYR A 93GLY A 109 | URA A 230 (-3.2A)NoneNoneNone | 0.92A | 11gsA-1flzA:undetectable | 11gsA-1flzA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1huj | INORGANICPYROPHOSPHATASE (Saccharomycescerevisiae) |
PF00719(Pyrophosphatase) | 4 | TYR A 15VAL A 17ILE A 49GLY A 132 | None | 0.93A | 11gsA-1hujA:undetectable | 11gsA-1hujA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jsc | ACETOHYDROXY-ACIDSYNTHASE (Saccharomycescerevisiae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | PHE A 111VAL A 159ILE A 182GLY A 143 | None | 0.95A | 11gsA-1jscA:0.0 | 11gsA-1jscA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ka9 | IMIDAZOLE GLYCEROLPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF00117(GATase) | 4 | TYR H 10PHE H 59VAL H 55ILE H 81 | None | 0.96A | 11gsA-1ka9H:undetectable | 11gsA-1ka9H:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 115PHE A 70ILE A 199GLY A 175 | None | 0.76A | 11gsA-1kgpA:undetectable | 11gsA-1kgpA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1j | HEAT SHOCK PROTEASEHTRA (Thermotogamaritima) |
PF13365(Trypsin_2) | 4 | PHE A 84VAL A 40ILE A 158GLY A 161 | None | 0.95A | 11gsA-1l1jA:undetectable | 11gsA-1l1jA:24.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbk | GLUTATHIONES-TRANSFERASE CLASSPI CHIMAERA (CODA) (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 6 | TYR A 7PHE A 8VAL A 10ARG A 13ILE A 104TYR A 108 | NoneGSH A 504 (-4.7A)NoneGSH A 504 (-3.7A)NoneNone | 0.59A | 11gsA-1lbkA:36.1 | 11gsA-1lbkA:97.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p9b | ADENYLOSUCCINATESYNTHETASE (Plasmodiumfalciparum) |
PF00709(Adenylsucc_synt) | 4 | PHE A 46ILE A 145TYR A 149GLY A 84 | NoneIMO A1601 ( 4.6A)NoneNone | 0.89A | 11gsA-1p9bA:undetectable | 11gsA-1p9bA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pz3 | ALPHA-L-ARABINOFURANOSIDASE (Geobacillusstearothermophilus) |
PF06964(Alpha-L-AF_C) | 4 | VAL A 413ILE A 23TYR A 24GLY A 383 | None | 0.81A | 11gsA-1pz3A:undetectable | 11gsA-1pz3A:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qc5 | PROTEIN (ALPHA1BETA1 INTEGRIN) (Homo sapiens) |
PF00092(VWA) | 4 | VAL B 338ARG B 466ILE B 456GLY B 415 | None | 0.92A | 11gsA-1qc5B:undetectable | 11gsA-1qc5B:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 105PHE A 60ILE A 189GLY A 165 | None | 0.83A | 11gsA-1r2fA:undetectable | 11gsA-1r2fA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sfj | 3-DEHYDROQUINATEDEHYDRATASE (Staphylococcusaureus) |
PF01487(DHquinase_I) | 4 | VAL A 4ARG A 202ILE A 192GLY A 210 | NoneDHK A 239 (-2.6A)DHK A 239 ( 4.2A)None | 0.96A | 11gsA-1sfjA:undetectable | 11gsA-1sfjA:22.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tu7 | GLUTATHIONES-TRANSFERASE 2 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 7PHE A 8TYR A 106GLY A 204 | NoneGSH A1001 (-4.8A)NoneNone | 0.40A | 11gsA-1tu7A:31.0 | 11gsA-1tu7A:42.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 110PHE A 65ILE A 194GLY A 170 | None | 0.81A | 11gsA-1uzrA:undetectable | 11gsA-1uzrA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xqp | 8-OXOGUANINE DNAGLYCOSYLASE (Pyrobaculumaerophilum) |
PF09171(AGOG) | 4 | PHE A 76VAL A 38ILE A 148GLY A 47 | None | 0.79A | 11gsA-1xqpA:undetectable | 11gsA-1xqpA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yew | PARTICULATE METHANEMONOOXYGENASESUBUNIT C2PARTICULATE METHANEMONOOXYGENASE, ASUBUNIT (Methylococcuscapsulatus) |
PF02461(AMO)PF04896(AmoC) | 4 | TYR C 146PHE B 31VAL B 34GLY B 95 | None | 0.93A | 11gsA-1yewC:undetectable | 11gsA-1yewC:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8q | U8 SNORNA-BINDINGPROTEIN X29 (Xenopus laevis) |
PF00293(NUDIX) | 5 | PHE A 172ARG A 156ILE A 54TYR A 160GLY A 168 | None | 1.35A | 11gsA-2a8qA:undetectable | 11gsA-2a8qA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b2x | INTEGRIN ALPHA-1 (Rattusnorvegicus) |
PF00092(VWA) | 4 | VAL A 152ARG A 280ILE A 270GLY A 229 | None | 0.87A | 11gsA-2b2xA:undetectable | 11gsA-2b2xA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gcu | PUTATIVEHYDROXYACYLGLUTATHIONE HYDROLASE 3 (Arabidopsisthaliana) |
PF00753(Lactamase_B) | 4 | TYR A 29PHE A 150ILE A 157GLY A 152 | NoneNoneEDO A2003 (-4.9A)None | 0.93A | 11gsA-2gcuA:undetectable | 11gsA-2gcuA:23.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gsr | CLASS PI GSTGLUTATHIONES-TRANSFERASE (Sus scrofa) |
PF02798(GST_N)PF14497(GST_C_3) | 6 | TYR A 7PHE A 8VAL A 10ARG A 13TYR A 106GLY A 203 | GTS A 208 (-4.5A)GTS A 208 (-4.7A)NoneGTS A 208 (-4.0A)NoneNone | 0.22A | 11gsA-2gsrA:35.4 | 11gsA-2gsrA:82.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gup | ROK FAMILY PROTEIN (Streptococcuspneumoniae) |
PF00480(ROK) | 4 | TYR A 78VAL A 76ILE A 30GLY A 9 | None | 0.81A | 11gsA-2gupA:undetectable | 11gsA-2gupA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnl | GLUTATHIONES-TRANSFERASE 1 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 32PHE A 33ARG A 38ILE A 127 | NoneNoneGSH A 501 (-4.3A)None | 0.61A | 11gsA-2hnlA:25.5 | 11gsA-2hnlA:28.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hp3 | IDS-EPIMERASE (Agrobacteriumtumefaciens) |
PF03972(MmgE_PrpD) | 4 | PHE A 371VAL A 306ILE A 393GLY A 373 | NoneNoneNoneUNX A1212 ( 3.6A) | 0.96A | 11gsA-2hp3A:undetectable | 11gsA-2hp3A:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iht | CARBOXYETHYLARGININESYNTHASE (Streptomycesclavuligerus) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | TYR A 561PHE A 412ILE A 460GLY A 411 | TPP A 600 ( 4.2A)NoneNoneTPP A 600 (-3.6A) | 0.88A | 11gsA-2ihtA:undetectable | 11gsA-2ihtA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8x | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus4) |
PF03167(UDG) | 5 | TYR A 93VAL A 105ILE A 118TYR A 119GLY A 135 | None | 1.05A | 11gsA-2j8xA:undetectable | 11gsA-2j8xA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jhq | URACILDNA-GLYCOSYLASE (Vibrio cholerae) |
PF03167(UDG) | 5 | TYR A 66VAL A 79ILE A 92TYR A 93GLY A 109 | None | 1.01A | 11gsA-2jhqA:undetectable | 11gsA-2jhqA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lj8 | COFILIN/ACTINDEPOLYMERIZINGFACTOR, PUTATIVE (Trypanosomabrucei) |
PF00241(Cofilin_ADF) | 4 | PHE A 57ILE A 36TYR A 34GLY A 54 | None | 0.84A | 11gsA-2lj8A:undetectable | 11gsA-2lj8A:25.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2msk | NITROGEN REGULATIONPROTEIN NR(I) (Salmonellaenterica) |
PF00072(Response_reg) | 4 | PHE A 33VAL A 9ILE A 69GLY A 36 | None | 0.92A | 11gsA-2mskA:undetectable | 11gsA-2mskA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p14 | HETERODIMERICRESTRICTIONENDONUCLEASER.BSPD6I SMALLSUBUNIT (Bacillus sp. D6) |
PF09491(RE_AlwI) | 4 | TYR A 8VAL A 135ILE A 72GLY A 110 | None | 0.85A | 11gsA-2p14A:undetectable | 11gsA-2p14A:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3e | DIAMINOPIMELATEDECARBOXYLASE (Aquifexaeolicus) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | TYR A 51ILE A 212TYR A 215GLY A 243 | None | 0.85A | 11gsA-2p3eA:undetectable | 11gsA-2p3eA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9u | A-TYPE FLAVOPROTEIN (Giardiaintestinalis) |
no annotation | 4 | PHE A 30VAL A 27ILE A 22GLY A 38 | NO3 A 501 (-4.7A)NoneNoneNone | 0.93A | 11gsA-2q9uA:undetectable | 11gsA-2q9uA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qiw | PEP PHOSPHONOMUTASE (Corynebacteriumglutamicum) |
PF13714(PEP_mutase) | 4 | VAL A 86ILE A 132TYR A 131GLY A 89 | None | 0.94A | 11gsA-2qiwA:undetectable | 11gsA-2qiwA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qru | UNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF07859(Abhydrolase_3) | 4 | TYR A 131ILE A 75TYR A 64GLY A 33 | NoneNoneNonePO4 A 273 ( 3.7A) | 0.93A | 11gsA-2qruA:undetectable | 11gsA-2qruA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c26 | PUTATIVEACETYLTRANSFERASETA0821 (Thermoplasmaacidophilum) |
PF00583(Acetyltransf_1) | 4 | VAL A 63ARG A 90ILE A 52GLY A 10 | NoneNO3 A 266 (-3.9A)NoneNone | 0.97A | 11gsA-3c26A:undetectable | 11gsA-3c26A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cr3 | PTS-DEPENDENTDIHYDROXYACETONEKINASE,PHOSPHOTRANSFERASESUBUNIT DHAM (Lactococcuslactis) |
PF03610(EIIA-man) | 4 | PHE C 88VAL C 90ILE C 7GLY C 95 | None | 0.92A | 11gsA-3cr3C:undetectable | 11gsA-3cr3C:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cxm | URACIL-DNAGLYCOSYLASE (Leishmanianaiffi) |
PF03167(UDG) | 5 | TYR A 208VAL A 221ILE A 234TYR A 235GLY A 251 | URB A 401 ( 3.3A)NoneNoneNoneNone | 1.00A | 11gsA-3cxmA:undetectable | 11gsA-3cxmA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6b | GLUTARYL-COADEHYDROGENASE (Burkholderiapseudomallei) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | TYR A 373VAL A 369ILE A 210GLY A 215 | None | 0.76A | 11gsA-3d6bA:1.5 | 11gsA-3d6bA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ftb | HISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Clostridiumacetobutylicum) |
PF00155(Aminotran_1_2) | 4 | PHE A 186ILE A 91TYR A 111GLY A 151 | None | 0.79A | 11gsA-3ftbA:undetectable | 11gsA-3ftbA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2t | BASEPLATE STRUCTURALPROTEIN GP6 (Escherichiavirus T4) |
no annotation | 4 | PHE A 517VAL A 538ILE A 592GLY A 556 | None | 0.86A | 11gsA-3h2tA:undetectable | 11gsA-3h2tA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i83 | 2-DEHYDROPANTOATE2-REDUCTASE (Methylococcuscapsulatus) |
PF02558(ApbA)PF08546(ApbA_C) | 4 | PHE A 127ILE A 11TYR A 15GLY A 144 | None | 0.86A | 11gsA-3i83A:undetectable | 11gsA-3i83A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igx | TRANSALDOLASE (Francisellatularensis) |
PF00923(TAL_FSA) | 4 | TYR A 217PHE A 222ILE A 143GLY A 174 | None | 0.65A | 11gsA-3igxA:undetectable | 11gsA-3igxA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3is6 | PUTATIVE PERMEASEPROTEIN, ABCTRANSPORTER (Porphyromonasgingivalis) |
PF12704(MacB_PCD) | 4 | TYR A 262VAL A 84ILE A 216GLY A 82 | None | 0.93A | 11gsA-3is6A:undetectable | 11gsA-3is6A:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3isl | PURINE CATABOLISMPROTEIN PUCG (Bacillussubtilis) |
PF00266(Aminotran_5) | 4 | PHE A 99VAL A 145ILE A 106GLY A 100 | PLP A 419 (-3.5A)NoneNoneNone | 0.89A | 11gsA-3islA:undetectable | 11gsA-3islA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kc2 | UNCHARACTERIZEDPROTEIN YKR070W (Saccharomycescerevisiae) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | TYR A 111VAL A 107ILE A 79GLY A 56 | None | 0.84A | 11gsA-3kc2A:undetectable | 11gsA-3kc2A:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3koy | D-ORNITHINEAMINOMUTASE ECOMPONENT (Acetoanaerobiumsticklandii) |
PF02310(B12-binding)PF09043(Lys-AminoMut_A)PF16554(OAM_dimer) | 4 | PHE A 87VAL A 130ILE A 105TYR A 157 | None | 0.85A | 11gsA-3koyA:undetectable | 11gsA-3koyA:15.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kux | PUTATIVEOXIDOREDUCTASE (Yersinia pestis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | PHE A 250ARG A 237TYR A 247GLY A 277 | None | 0.88A | 11gsA-3kuxA:undetectable | 11gsA-3kuxA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m16 | TRANSALDOLASE (Oleispiraantarctica) |
PF00923(TAL_FSA) | 4 | TYR A 220PHE A 225ILE A 147GLY A 178 | None | 0.77A | 11gsA-3m16A:undetectable | 11gsA-3m16A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 115PHE A 70ILE A 199GLY A 175 | None | 0.82A | 11gsA-3mjoA:undetectable | 11gsA-3mjoA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 4 | TYR B 105PHE B 60ILE B 189GLY B 165 | None | 0.96A | 11gsA-3n3bB:undetectable | 11gsA-3n3bB:19.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3o76 | GLUTATHIONES-TRANSFERASE P 1 (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 6 | TYR A 7PHE A 8VAL A 10ARG A 13TYR A 108GLY A 205 | NoneGTB A 210 (-4.5A)NoneGTB A 210 (-3.9A)GTB A 210 (-4.1A)GTB A 210 (-3.7A) | 0.31A | 11gsA-3o76A:36.5 | 11gsA-3o76A:84.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pvz | UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (Aliivibriofischeri) |
PF02719(Polysacc_synt_2) | 4 | TYR A 157VAL A 113ILE A 95TYR A 100 | NoneNoneNAD A 501 (-3.9A)None | 0.88A | 11gsA-3pvzA:undetectable | 11gsA-3pvzA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s88 | 16F6 - HEAVY CHAINENVELOPEGLYCOPROTEIN (Mus musculus;Sudanebolavirus) |
PF01611(Filo_glycop)PF07654(C1-set)PF07686(V-set) | 4 | TYR H 31VAL I 45ILE I 48GLY I 36 | None | 0.95A | 11gsA-3s88H:undetectable | 11gsA-3s88H:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sh5 | LG3 PEPTIDE (Homo sapiens) |
PF00054(Laminin_G_1) | 4 | PHE A 152VAL A 144ILE A 138GLY A 155 | None | 0.76A | 11gsA-3sh5A:undetectable | 11gsA-3sh5A:24.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t90 | GLUCOSE-6-PHOSPHATEACETYLTRANSFERASE 1 (Arabidopsisthaliana) |
PF00583(Acetyltransf_1) | 4 | PHE A 107VAL A 104ILE A 64GLY A 68 | None | 0.83A | 11gsA-3t90A:undetectable | 11gsA-3t90A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbj | ACTIBIND (Aspergillusniger) |
PF00445(Ribonuclease_T2) | 4 | TYR A 237VAL A 228ILE A 145GLY A 230 | None | 0.87A | 11gsA-3tbjA:undetectable | 11gsA-3tbjA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr7 | URACIL-DNAGLYCOSYLASE (Coxiellaburnetii) |
PF03167(UDG) | 4 | TYR A 69VAL A 82ILE A 95GLY A 111 | None | 0.89A | 11gsA-3tr7A:undetectable | 11gsA-3tr7A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ue9 | ADENYLOSUCCINATESYNTHETASE (Burkholderiathailandensis) |
PF00709(Adenylsucc_synt) | 4 | PHE A 43ILE A 143TYR A 147GLY A 81 | None | 0.94A | 11gsA-3ue9A:undetectable | 11gsA-3ue9A:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdj | TYPE I PULLULANASE (Anoxybacillussp. LM18-11) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | VAL A 592ILE A 267TYR A 225GLY A 569 | None | 0.89A | 11gsA-3wdjA:undetectable | 11gsA-3wdjA:14.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zoq | URACIL-DNAGLYCOSYLASE (Bacillussubtilis) |
PF03167(UDG) | 4 | TYR A 67VAL A 80ILE A 93GLY A 109 | None | 0.96A | 11gsA-3zoqA:undetectable | 11gsA-3zoqA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 4 | PHE A 539ILE A 254TYR A 506GLY A 537 | None | 0.80A | 11gsA-4aioA:undetectable | 11gsA-4aioA:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bg2 | PATF (Prochlorondidemni) |
no annotation | 4 | PHE A 27VAL A 29TYR A 67GLY A 65 | None | 0.82A | 11gsA-4bg2A:undetectable | 11gsA-4bg2A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4chl | PERSULFIDEDIOXYGENASE ETHE1,MITOCHONDRIAL (Homo sapiens) |
PF00753(Lactamase_B) | 4 | TYR A 38PHE A 151ILE A 158GLY A 153 | None | 0.94A | 11gsA-4chlA:undetectable | 11gsA-4chlA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4con | ANAEROBICRIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE (Thermotogamaritima) |
PF13597(NRDD) | 4 | TYR A 227ILE A 555TYR A 584GLY A 361 | None | 0.94A | 11gsA-4conA:undetectable | 11gsA-4conA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecn | LEUCINE-RICH REPEATPROTEIN (Bacteroidesthetaiotaomicron) |
PF14660(DUF4458) | 4 | PHE A 394ARG A 412ILE A 580TYR A 582 | None | 0.83A | 11gsA-4ecnA:undetectable | 11gsA-4ecnA:12.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fqj | HEMAGGLUTININ (Influenza Bvirus) |
PF00509(Hemagglutinin) | 4 | TYR A 202VAL A 160ILE A 243GLY A 138 | None | 0.93A | 11gsA-4fqjA:undetectable | 11gsA-4fqjA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hdt | 3-HYDROXYISOBUTYRYL-COA HYDROLASE (Mycolicibacteriumthermoresistibile) |
PF16113(ECH_2) | 4 | TYR A 92VAL A 148ILE A 73GLY A 116 | None | 0.82A | 11gsA-4hdtA:undetectable | 11gsA-4hdtA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hst | GLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE BETA CHAIN (Pseudomonas) |
PF01804(Penicil_amidase) | 4 | TYR B 32PHE B 31VAL B 49ILE B 176 | GLJ B 601 (-4.9A)NoneNoneNone | 0.96A | 11gsA-4hstB:undetectable | 11gsA-4hstB:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lyl | URACIL-DNAGLYCOSYLASE (Gadus morhua) |
PF03167(UDG) | 5 | TYR A 147VAL A 160ILE A 173TYR A 174GLY A 190 | None | 1.02A | 11gsA-4lylA:undetectable | 11gsA-4lylA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1b | POLYSACCHARIDEDEACETYLASE (Bacillusanthracis) |
PF01522(Polysacc_deac_1) | 4 | ARG A 132ILE A 167TYR A 123GLY A 117 | None | 0.93A | 11gsA-4m1bA:undetectable | 11gsA-4m1bA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 104PHE A 59ILE A 188GLY A 164 | None | 0.89A | 11gsA-4n83A:undetectable | 11gsA-4n83A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4na3 | POLYKETIDE SYNTHASEPKSJ (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | ARG A 266ILE A 300TYR A 295GLY A 427 | None | 0.87A | 11gsA-4na3A:undetectable | 11gsA-4na3A:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 4 | VAL A 938ARG A 933ILE A 943GLY A 919 | EDO A1104 (-4.7A)NoneNoneNone | 0.96A | 11gsA-4nmeA:undetectable | 11gsA-4nmeA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o0l | NADPH-DEPENDENT3-QUINUCLIDINONEREDUCTASE (Rhodotorulamucilaginosa) |
PF13561(adh_short_C2) | 4 | PHE A 76VAL A 78ILE A 33GLY A 53 | None | 0.84A | 11gsA-4o0lA:undetectable | 11gsA-4o0lA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pue | ENDO-1,4-BETA-XYLANASE (Geobacillusstearothermophilus) |
PF00331(Glyco_hydro_10) | 4 | PHE A 360ILE A 284TYR A 281GLY A 363 | None | 0.67A | 11gsA-4pueA:undetectable | 11gsA-4pueA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3m | 2-DEHYDROPANTOATE2-REDUCTASE (Staphylococcusaureus) |
PF02558(ApbA)PF08546(ApbA_C) | 4 | TYR A 40VAL A 126ILE A 117GLY A 11 | NoneNoneNoneNAP A 500 (-3.1A) | 0.85A | 11gsA-4s3mA:undetectable | 11gsA-4s3mA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | VAL A 23ILE A 31TYR A 125GLY A 48 | None | 0.88A | 11gsA-4tr6A:undetectable | 11gsA-4tr6A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uqm | URACIL-DNAGLYCOSYLASE (Deinococcusradiodurans) |
PF03167(UDG) | 5 | TYR A 85VAL A 98ILE A 111TYR A 112GLY A 128 | CL A1245 (-4.3A)NoneNoneNoneNone | 1.08A | 11gsA-4uqmA:undetectable | 11gsA-4uqmA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1e | PECTINESTERASE (Aspergillusniger) |
PF01095(Pectinesterase) | 4 | TYR A 73VAL A 102TYR A 67GLY A 89 | None | 0.93A | 11gsA-5c1eA:undetectable | 11gsA-5c1eA:20.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5d73 | GLUTATHIONES-TRANSFERASE (Wuchereriabancrofti) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 7PHE A 8TYR A 106GLY A 204 | NoneGSH A 301 (-4.9A)NoneNone | 0.39A | 11gsA-5d73A:31.0 | 11gsA-5d73A:42.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dis | GTP-BINDING NUCLEARPROTEIN RAN (Homo sapiens) |
PF00071(Ras) | 4 | TYR B 155VAL B 124TYR B 146GLY B 121 | None | 0.95A | 11gsA-5disB:undetectable | 11gsA-5disB:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4y | HOMOSERINEO-ACETYLTRANSFERASE (Pseudomonasveronii) |
PF00561(Abhydrolase_1) | 4 | TYR A 194PHE A 189VAL A 200GLY A 203 | None | 0.96A | 11gsA-5e4yA:undetectable | 11gsA-5e4yA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewo | STRUCTURAL PROTEIN (Mamastrovirus 1) |
PF12226(Astro_capsid_p) | 4 | TYR A 588PHE A 582VAL A 543GLY A 546 | None | 0.92A | 11gsA-5ewoA:undetectable | 11gsA-5ewoA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEOSOME SUBUNITALPHA TYPE 1,PUTATIVE (Plasmodiumfalciparum) |
PF00227(Proteasome)PF10584(Proteasome_A_N) | 4 | TYR F 116PHE F 128ILE F 72GLY F 76 | None | 0.94A | 11gsA-5fmgF:undetectable | 11gsA-5fmgF:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5frs | SISTER CHROMATIDCOHESION PROTEINPDS5 (Saccharomycescerevisiae) |
PF12717(Cnd1) | 4 | TYR A 157VAL A 219ILE A 179GLY A 172 | None | 0.86A | 11gsA-5frsA:undetectable | 11gsA-5frsA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB2 (Saccharomycescerevisiae) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | TYR B 859VAL B 968ARG B 942GLY B 947 | None | 0.84A | 11gsA-5ip9B:undetectable | 11gsA-5ip9B:10.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jk7 | URACIL-DNAGLYCOSYLASE (Homo sapiens) |
PF03167(UDG) | 4 | VAL D 160ILE D 173TYR D 174GLY D 190 | None | 0.92A | 11gsA-5jk7D:undetectable | 11gsA-5jk7D:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 4 | TYR B 196PHE B 76ILE B 249GLY B 80 | None | 0.83A | 11gsA-5kohB:undetectable | 11gsA-5kohB:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve3 | BPPRF (Paraburkholderiaphytofirmans) |
no annotation | 4 | TYR B 17PHE B 130ILE B 137GLY B 132 | None | 0.93A | 11gsA-5ve3B:undetectable | 11gsA-5ve3B:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x55 | PROBABLE URACIL-DNAGLYCOSYLASE (Acanthamoebapolyphagamimivirus) |
PF03167(UDG) | 5 | TYR A 193VAL A 211ILE A 224TYR A 225GLY A 241 | None | 0.95A | 11gsA-5x55A:undetectable | 11gsA-5x55A:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfa | NAD-REDUCINGHYDROGENASE (Hydrogenophilusthermoluteolus) |
PF00374(NiFeSe_Hases) | 4 | TYR D 308PHE D 244VAL D 310GLY D 397 | None | 0.96A | 11gsA-5xfaD:undetectable | 11gsA-5xfaD:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwb | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Colwelliapsychrerythraea) |
PF00275(EPSP_synthase) | 4 | PHE A 250VAL A 261ILE A 9GLY A 254 | None | 0.92A | 11gsA-5xwbA:undetectable | 11gsA-5xwbA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y0q | UPF0348 PROTEINB4417_3650 (Bacillussubtilis) |
no annotation | 4 | TYR A 72PHE A 41VAL A 76GLY A 45 | None | 0.88A | 11gsA-5y0qA:undetectable | 11gsA-5y0qA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y37 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Streptococcusagalactiae) |
no annotation | 4 | VAL A 123ILE A 17TYR A 324GLY A 153 | NoneNAD A 401 (-4.3A)NAD A 401 (-3.6A)None | 0.92A | 11gsA-5y37A:undetectable | 11gsA-5y37A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z5k | DRAXINNETRIN RECEPTOR DCC (Rattusnorvegicus) |
no annotation | 4 | ARG B 282ILE A 387TYR A 398GLY A 396 | None | 0.95A | 11gsA-5z5kB:undetectable | 11gsA-5z5kB:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zal | ENDORIBONUCLEASEDICER (Homo sapiens) |
no annotation | 4 | TYR A 452VAL A 309ILE A 355GLY A 314 | None | 0.97A | 11gsA-5zalA:undetectable | 11gsA-5zalA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ap4 | DNA POLYMERASE IIISUBUNIT BETA (Acinetobacterbaumannii) |
no annotation | 4 | VAL A 21ILE A 29TYR A 119GLY A 46 | None | 0.89A | 11gsA-6ap4A:undetectable | 11gsA-6ap4A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsw | MU CLASS GLUTATHIONES-TRANSFERASE OFISOENZYME 3-3 (Rattus rattus) |
PF00043(GST_C)PF02798(GST_N) | 4 | TYR A 6VAL A 9ILE A 111TYR A 115 | NoneNoneGPS A 221 (-4.5A)None | 0.89A | 11gsA-6gswA:25.7 | 11gsA-6gswA:30.00 |