DRUG BINDING INTERFACES MAPPED TO 'TOPOTECAN'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1K4T_D_TTCD990 1k4t TTC

DB01030
(Topotecan)
;
Homo sapiens
DNA TOPOISOMERASE I PF01028
(Topoisom_I)
PF02919
(Topoisom_I_N)
PF14370
(Topo_C_assoc)
no annotation
5 GLU A 356
ARG A 364
LYS A 532
ASP A 533
THR A 718
TTC D 990
1RR8_A_TTCA100 1rr8 TTC

DB01030
(Topotecan)
;
Homo sapiens
DNA TOPOISOMERASE I PF01028
(Topoisom_I)
PF02919
(Topoisom_I_N)
PF14370
(Topo_C_assoc)
no annotation
5 GLU C 356
ARG C 364
LYS C 532
ASP C 533
THR C 718
TTC A 100
1RRJ_B_TTCB990 1rrj TTC

DB01030
(Topotecan)
;
Homo sapiens
DNA TOPOISOMERASE I PF01028
(Topoisom_I)
PF02919
(Topoisom_I_N)
PF14370
(Topo_C_assoc)
no annotation
5 GLU A 356
ARG A 364
LYS A 532
ASP A 533
THR A 718
TTC B 990