DRUG BINDING INTERFACES MAPPED TO 'TOBRAMYCIN'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1M4D_A_TOYA500	1m4d	TOY DB00684 (Tobramycin)	Mycobacterium tuberculosis	AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE	PF13527 (Acetyltransf_9)	10	PHE A 32 ASP A 35 ASP A 40 GLU A 82 SER A 117 SER A 119 ALA A 120 ASP A 152 THR A 155 ASP A 179	TOY A 500
1M4D_B_TOYB501	1m4d	TOY DB00684 (Tobramycin)	Mycobacterium tuberculosis	AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE	no annotation	9	ASP B 35 ASP B 40 GLU B 82 SER B 117 SER B 119 ALA B 120 ASP B 152 THR B 155 ASP B 179	TOY B 501
3SG8_A_TOYA305	3sg8	TOY DB00684 (Tobramycin)	Enterococcus casseliflavus	APH(2'')-ID	PF01636 (APH)	13	ASN A 32 ASP A 197 SER A 199 ASP A 201 HIS A 202 ASP A 220 GLU A 235 GLU A 238 GLU A 239 TRP A 271 GLU A 274 TYR A 278 TRP A 287	TOY A 305
3SG8_B_TOYB305	3sg8	TOY DB00684 (Tobramycin)	Enterococcus casseliflavus	APH(2'')-ID	no annotation	12	ASN B 32 ASP B 197 SER B 199 ASP B 201 HIS B 202 ASP B 220 GLU B 235 GLU B 238 GLU B 239 TRP B 271 TYR B 278 TRP B 287	TOY B 305
3VET_A_TOYA604	3vet	TOY DB00684 (Tobramycin)	Streptoalloteichu s tenebrarius	O-CARBAMOYLTRANSFERA SE TOBZ	PF02543 (Carbam_trans_N) PF16861 (Carbam_trans_C)	9	ASP A 12 HIS A 14 TYR A 42 PHE A 169 GLU A 172 GLU A 176 ASP A 183 ASP A 228 TYR A 230	TOY A 604
4EBK_A_TOYA301	4ebk	TOY DB00684 (Tobramycin)	Pseudomonas aeruginosa	AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERA SE	PF01909 (NTP_transf_2) no annotation	9	ASP B 40 GLU B 51 TYR B 53 ALA B 70 GLU A 122 GLU A 124 GLU A 126 ASP A 127 GLU A 130	TOY A 301
4EBK_B_TOYB302	4ebk	TOY DB00684 (Tobramycin)	Pseudomonas aeruginosa	AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERA SE	PF01909 (NTP_transf_2) no annotation	9	ASP A 40 GLU A 51 TYR A 53 ALA A 70 GLU B 122 GLU B 124 GLU B 126 ASP B 127 GLU B 130	TOY B 302
4EVY_A_TOYA201	4evy	TOY DB00684 (Tobramycin)	Acinetobacter haemolyticus	AMINOGLYCOSIDE N(6')-ACETYLTRANSFER ASE TYPE 1	PF00583 (Acetyltransf_1) no annotation	9	ARG A 18 TRP A 22 GLU A 32 TYR B 65 ASN B 67 GLU A 78 GLY A 79 ASP A 114 GLU B 135	TOY A 201
4EVY_B_TOYB201	4evy	TOY DB00684 (Tobramycin)	Acinetobacter haemolyticus	AMINOGLYCOSIDE N(6')-ACETYLTRANSFER ASE TYPE 1	PF00583 (Acetyltransf_1) no annotation	10	ARG B 18 TRP B 22 ASP B 24 GLU B 32 TYR A 65 ASN A 67 GLU B 78 GLY B 79 ASP B 114 GLU A 135	TOY B 201
4JD6_A_TOYA501	4jd6	TOY DB00684 (Tobramycin)	Mycobacterium tuberculosis	ENHANCED INTRACELLULAR SURVIVAL PROTEIN	PF13527 (Acetyltransf_9) PF13530 (SCP2_2)	9	PHE A 24 ASP A 26 ILE A 28 TRP A 36 SER A 83 VAL A 85 TYR A 126 GLU A 203 GLU A 401	TOY A 501
4JD6_B_TOYB501	4jd6	TOY DB00684 (Tobramycin)	Mycobacterium tuberculosis	ENHANCED INTRACELLULAR SURVIVAL PROTEIN	no annotation	9	PHE B 24 ASP B 26 ILE B 28 TRP B 36 SER B 83 VAL B 85 TYR B 126 GLU B 203 GLU B 401	TOY B 501
4XJE_A_TOYA202	4xje	TOY DB00684 (Tobramycin)	Pseudomonas aeruginosa	AADB	PF10706 (Aminoglyc_resit)	8	ASP A 44 ASP A 46 TYR A 74 ASP A 86 GLU A 88 ILE A 99 ASP A 131 TYR A 134	TOY A 202
5CFS_A_TOYA203	5cfs	TOY DB00684 (Tobramycin)	Pseudomonas aeruginosa	AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN	PF10706 (Aminoglyc_resit)	8	ASP A 44 ASP A 46 TYR A 74 ASP A 86 GLU A 88 ILE A 99 ASP A 131 TYR A 134	TOY A 203

[["1M4D_A_TOYA500","1m4d","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","PF13527(Acetyltransf_9)",10,"PHE A  32;ASP A  35;ASP A  40;GLU A  82;SER A 117;SER A 119;ALA A 120;ASP A 152;THR A 155;ASP A 179","TOY A 500\r"],["1M4D_B_TOYB501","1m4d","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","no annotation",9,"ASP B  35;ASP B  40;GLU B  82;SER B 117;SER B 119;ALA B 120;ASP B 152;THR B 155;ASP B 179","TOY B 501\r"],["3SG8_A_TOYA305","3sg8","TOY","DB00684(Tobramycin)","Enterococcus casseliflavus","APH(2'')-ID","PF01636(APH)",13,"ASN A  32;ASP A 197;SER A 199;ASP A 201;HIS A 202;ASP A 220;GLU A 235;GLU A 238;GLU A 239;TRP A 271;GLU A 274;TYR A 278;TRP A 287","TOY A 305\r"],["3SG8_B_TOYB305","3sg8","TOY","DB00684(Tobramycin)","Enterococcus casseliflavus","APH(2'')-ID","no annotation",12,"ASN B  32;ASP B 197;SER B 199;ASP B 201;HIS B 202;ASP B 220;GLU B 235;GLU B 238;GLU B 239;TRP B 271;TYR B 278;TRP B 287","TOY B 305\r"],["3VET_A_TOYA604","3vet","TOY","DB00684(Tobramycin)","Streptoalloteichus tenebrarius","O-CARBAMOYLTRANSFERASE TOBZ","PF02543(Carbam_trans_N);PF16861(Carbam_trans_C)",9,"ASP A  12;HIS A  14;TYR A  42;PHE A 169;GLU A 172;GLU A 176;ASP A 183;ASP A 228;TYR A 230","TOY A 604\r"],["4EBK_A_TOYA301","4ebk","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE","PF01909(NTP_transf_2);no annotation",9,"ASP B  40;GLU B  51;TYR B  53;ALA B  70;GLU A 122;GLU A 124;GLU A 126;ASP A 127;GLU A 130","TOY A 301\r"],["4EBK_B_TOYB302","4ebk","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE","PF01909(NTP_transf_2);no annotation",9,"ASP A  40;GLU A  51;TYR A  53;ALA A  70;GLU B 122;GLU B 124;GLU B 126;ASP B 127;GLU B 130","TOY B 302\r"],["4EVY_A_TOYA201","4evy","TOY","DB00684(Tobramycin)","Acinetobacter haemolyticus","AMINOGLYCOSIDE N(6')-ACETYLTRANSFERASE TYPE 1","PF00583(Acetyltransf_1);no annotation",9,"ARG A  18;TRP A  22;GLU A  32;TYR B  65;ASN B  67;GLU A  78;GLY A  79;ASP A 114;GLU B 135","TOY A 201\r"],["4EVY_B_TOYB201","4evy","TOY","DB00684(Tobramycin)","Acinetobacter haemolyticus","AMINOGLYCOSIDE N(6')-ACETYLTRANSFERASE TYPE 1","PF00583(Acetyltransf_1);no annotation",10,"ARG B  18;TRP B  22;ASP B  24;GLU B  32;TYR A  65;ASN A  67;GLU B  78;GLY B  79;ASP B 114;GLU A 135","TOY B 201\r"],["4JD6_A_TOYA501","4jd6","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","PF13527(Acetyltransf_9);PF13530(SCP2_2)",9,"PHE A  24;ASP A  26;ILE A  28;TRP A  36;SER A  83;VAL A  85;TYR A 126;GLU A 203;GLU A 401","TOY A 501\r"],["4JD6_B_TOYB501","4jd6","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","no annotation",9,"PHE B  24;ASP B  26;ILE B  28;TRP B  36;SER B  83;VAL B  85;TYR B 126;GLU B 203;GLU B 401","TOY B 501\r"],["4XJE_A_TOYA202","4xje","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AADB","PF10706(Aminoglyc_resit)",8,"ASP A  44;ASP A  46;TYR A  74;ASP A  86;GLU A  88;ILE A  99;ASP A 131;TYR A 134","TOY A 202\r"],["5CFS_A_TOYA203","5cfs","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN","PF10706(Aminoglyc_resit)",8,"ASP A  44;ASP A  46;TYR A  74;ASP A  86;GLU A  88;ILE A  99;ASP A 131;TYR A 134","TOY A 203\r"]]