DRUG BINDING INTERFACES MAPPED TO 'TETRACYCLINE'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
2FJ1_A_CTCA222
2fj1
CTC
DB09093(Chlortetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR PROTEINCLASS D
PF00440(TetR_N)PF02909(TetR_C)
13
HIS A 64SER A 67ASN A 82PHE A 86HIS A 100ARG A 104PRO A 105THR A 112VAL A 113GLN A 116LEU A 131ILE A 134SER A 138
CTC A 222
2HCJ_B_TACB888
2hcj
TAC
DB00759(Tetracycline)
Escherichia coli
PROTEIN CHAINELONGATION FACTOREF-TU
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2)
4
THR A 25SER B 65ASP B 80PRO B 82
TAC B 888
2HDN_B_TACB1888
2hdn
TAC
DB00759(Tetracycline)
Escherichia coli
ELONGATION FACTOREF-TU
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2)no annotation
5
THR A 25SER B 65SER D 65ASP B 80PRO B 82
TAC B1888
2HDN_D_TACD2888
2hdn
TAC
DB00759(Tetracycline)
Escherichia coli
ELONGATION FACTOREF-TU
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2)no annotation
5
THR C 25SER B 65SER D 65ASP D 80PRO D 82
TAC D2888
2HDN_F_TACF3888
2hdn
TAC
DB00759(Tetracycline)
Escherichia coli
ELONGATION FACTOREF-TU
no annotation
7
THR E 25SER H 65SER F 65VAL H 67ASP F 80PRO F 82LEU H 178
TAC F3888
2HDN_H_TACH4888
2hdn
TAC
DB00759(Tetracycline)
Escherichia coli
ELONGATION FACTOREF-TU
no annotation
7
THR G 25SER H 65SER F 65VAL F 67ASP H 80PRO H 82LEU F 178
TAC H4888
2HDN_J_TACJ5888
2hdn
TAC
DB00759(Tetracycline)
Escherichia coli
ELONGATION FACTOREF-TU
no annotation
6
THR I 25SER L 65SER J 65VAL L 67ASP J 80PRO J 82
TAC J5888
2HDN_L_TACL6888
2hdn
TAC
DB00759(Tetracycline)
Escherichia coli
ELONGATION FACTOREF-TU
no annotation
6
THR K 25SER L 65SER J 65VAL J 67ASP L 80PRO L 82
TAC L6888
2TCT_A_CTCA222
2tct
CTC
DB09093(Chlortetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR
PF00440(TetR_C)PF02909(TetR_N)
13
HIS A 64SER A 67ASN A 82PHE A 86HIS A 100ARG A 104PRO A 105GLN A 109THR A 112VAL A 113GLN A 116ILE A 134SER A 138
CTC A 222
2TRT_A_TACA222
2trt
TAC
DB00759(Tetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR CLASS D
PF00440(TetR_N)PF02909(TetR_C)
11
HIS A 64SER A 67ASN A 82PHE A 86HIS A 100ARG A 104PRO A 105VAL A 113GLN A 116ILE A 134SER A 138
TAC A 222
2UXO_B_TACB1211
2uxo
TAC
DB00759(Tetracycline)
Pseudomonasputida
HTH-TYPETRANSCRIPTIONALREGULATOR TTGR
no annotation
11
LEU B 66HIS B 70LEU B 92VAL B 96ASN B 110LEU B 113CYS B 137ILE B 141MET B 167VAL B 171ILE B 175
TAC B1211
2VKE_A_TACA222
2vke
TAC
DB00759(Tetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR PROTEINCLASS D
PF00440(TetR_N)PF02909(TetR_C)
11
HIS A 64SER A 67ASN A 82PHE A 86HIS A 100ARG A 104PRO A 105VAL A 113GLN A 116ILE A 134SER A 138
TAC A 222
2XPW_A_OTCA222
2xpw
OTC
DB00595(Oxytetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR PROTEINCLASS D
PF00440(TetR_N)PF02909(TetR_C)
12
LEU A 60HIS A 64SER A 67ASN A 82PHE A 86HIS A 100ARG A 104PRO A 105VAL A 113GLN A 116ILE A 134SER A 138
OTC A 222
2Y6R_A_CTCA1385
2y6r
CTC
DB09093(Chlortetracycline)
Bacteroidesthetaiotaomicron
TETX2 PROTEIN
PF01494(FAD_binding_3)
10
ASP A 61GLN A 192ARG A 213MET A 215PHE A 224ASN A 226GLY A 236PRO A 318GLY A 321MET A 375
CTC A1385
2Y6R_B_CTCB1385
2y6r
CTC
DB09093(Chlortetracycline)
Bacteroidesthetaiotaomicron
TETX2 PROTEIN
None
8
GLN B 192ARG B 213MET B 215PHE B 224GLY B 236PRO B 318GLY B 321MET B 375
CTC B1385
2Y6R_C_CTCC1385
2y6r
CTC
DB09093(Chlortetracycline)
Bacteroidesthetaiotaomicron
TETX2 PROTEIN
None
12
ASP C 61ASN C 190GLN C 192ARG C 213MET C 215PHE C 224HIS C 234GLY C 236SER C 238PRO C 318GLY C 321MET C 375
CTC C1385
2Y6R_D_CTCD1385
2y6r
CTC
DB09093(Chlortetracycline)
Bacteroidesthetaiotaomicron
TETX2 PROTEIN
None
10
ASP D 61GLN D 192ARG D 213MET D 215PHE D 224HIS D 234GLY D 236SER D 238PRO D 318MET D 375
CTC D1385
3Q5P_A_TACA7101
3q5p
TAC
DB00759(Tetracycline)
Bacillus subtilis
MULTIDRUG-EFFLUXTRANSPORTER 1REGULATOR
PF06445(GyrI-like)PF13411(MerR_1)
12
PRO A 144VAL A 147ASN A 149TYR A 152TYR A 170ILE A 182TYR A 187PHE A 224TYR A 229GLU A 253ILE A 255TYR A 268
TAC A7101
4B3A_A_TACA222
4b3a
TAC
DB00759(Tetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR PROTEINCLASS D
PF00440(TetR_N)PF02909(TetR_C)
12
LEU A 60HIS A 64SER A 67ASN A 82PHE A 86ARG A 104PRO A 105GLN A 109VAL A 113GLN A 116ILE A 134SER A 138
TAC A 222
4V2G_B_CTCB222
4v2g
CTC
DB09093(Chlortetracycline)
Escherichia coli
TETRACYCLINEREPRESSOR PROTEINCLASS D
NonePF00440(TetR_N)PF02909(TetR_C)
14
HIS B 64SER B 67ASN B 82PHE B 86HIS B 100ARG B 104PRO B 105THR B 112VAL B 113GLN B 116ILE B 134SER B 138LEU A 170LEU A 174
CTC B 222
5TUI_B_CTCB405
5tui
CTC
DB09093(Chlortetracycline)
unculturedbacterium
TETRACYCLINEDESTRUCTASE TET(50)
None
17
ASP B 47ARG B 49GLY B 94PHE B 95ARG B 96GLU B 102VAL B 181LEU B 198LEU B 205THR B 207GLY B 220MET B 222PRO B 296GLY B 299PHE B 344VAL B 348ILE B 371
CTC B 405
[["2FJ1_A_CTCA222","2fj1","CTC","DB09093(Chlortetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR PROTEIN CLASS D","PF00440(TetR_N);PF02909(TetR_C)",13,"HIS A 64;SER A 67;ASN A 82;PHE A 86;HIS A 100;ARG A 104;PRO A 105;THR A 112;VAL A 113;GLN A 116;LEU A 131;ILE A 134;SER A 138","CTC A 222\r"],["2HCJ_B_TACB888","2hcj","TAC","DB00759(Tetracycline)","Escherichia coli","PROTEIN CHAIN ELONGATION FACTOR EF-TU","PF00009(GTP_EFTU);PF03143(GTP_EFTU_D3);PF03144(GTP_EFTU_D2)",4,"THR A 25;SER B 65;ASP B 80;PRO B 82","TAC B 888\r"],["2HDN_B_TACB1888","2hdn","TAC","DB00759(Tetracycline)","Escherichia coli","ELONGATION FACTOR EF-TU","PF00009(GTP_EFTU);PF03143(GTP_EFTU_D3);PF03144(GTP_EFTU_D2);no annotation",5,"THR A 25;SER B 65;SER D 65;ASP B 80;PRO B 82","TAC B1888\r"],["2HDN_D_TACD2888","2hdn","TAC","DB00759(Tetracycline)","Escherichia coli","ELONGATION FACTOR EF-TU","PF00009(GTP_EFTU);PF03143(GTP_EFTU_D3);PF03144(GTP_EFTU_D2);no annotation",5,"THR C 25;SER B 65;SER D 65;ASP D 80;PRO D 82","TAC D2888\r"],["2HDN_F_TACF3888","2hdn","TAC","DB00759(Tetracycline)","Escherichia coli","ELONGATION FACTOR EF-TU","no annotation",7,"THR E 25;SER H 65;SER F 65;VAL H 67;ASP F 80;PRO F 82;LEU H 178","TAC F3888\r"],["2HDN_H_TACH4888","2hdn","TAC","DB00759(Tetracycline)","Escherichia coli","ELONGATION FACTOR EF-TU","no annotation",7,"THR G 25;SER H 65;SER F 65;VAL F 67;ASP H 80;PRO H 82;LEU F 178","TAC H4888\r"],["2HDN_J_TACJ5888","2hdn","TAC","DB00759(Tetracycline)","Escherichia coli","ELONGATION FACTOR EF-TU","no annotation",6,"THR I 25;SER L 65;SER J 65;VAL L 67;ASP J 80;PRO J 82","TAC J5888\r"],["2HDN_L_TACL6888","2hdn","TAC","DB00759(Tetracycline)","Escherichia coli","ELONGATION FACTOR EF-TU","no annotation",6,"THR K 25;SER L 65;SER J 65;VAL J 67;ASP L 80;PRO L 82","TAC L6888\r"],["2TCT_A_CTCA222","2tct","CTC","DB09093(Chlortetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR","PF00440(TetR_C);PF02909(TetR_N)",13,"HIS A 64;SER A 67;ASN A 82;PHE A 86;HIS A 100;ARG A 104;PRO A 105;GLN A 109;THR A 112;VAL A 113;GLN A 116;ILE A 134;SER A 138","CTC A 222\r"],["2TRT_A_TACA222","2trt","TAC","DB00759(Tetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR CLASS D","PF00440(TetR_N);PF02909(TetR_C)",11,"HIS A 64;SER A 67;ASN A 82;PHE A 86;HIS A 100;ARG A 104;PRO A 105;VAL A 113;GLN A 116;ILE A 134;SER A 138","TAC A 222\r"],["2UXO_B_TACB1211","2uxo","TAC","DB00759(Tetracycline)","Pseudomonas putida","HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR","no annotation",11,"LEU B 66;HIS B 70;LEU B 92;VAL B 96;ASN B 110;LEU B 113;CYS B 137;ILE B 141;MET B 167;VAL B 171;ILE B 175","TAC B1211\r"],["2VKE_A_TACA222","2vke","TAC","DB00759(Tetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR PROTEIN CLASS D","PF00440(TetR_N);PF02909(TetR_C)",11,"HIS A 64;SER A 67;ASN A 82;PHE A 86;HIS A 100;ARG A 104;PRO A 105;VAL A 113;GLN A 116;ILE A 134;SER A 138","TAC A 222\r"],["2XPW_A_OTCA222","2xpw","OTC","DB00595(Oxytetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR PROTEIN CLASS D","PF00440(TetR_N);PF02909(TetR_C)",12,"LEU A 60;HIS A 64;SER A 67;ASN A 82;PHE A 86;HIS A 100;ARG A 104;PRO A 105;VAL A 113;GLN A 116;ILE A 134;SER A 138","OTC A 222\r"],["2Y6R_A_CTCA1385","2y6r","CTC","DB09093(Chlortetracycline)","Bacteroides thetaiotaomicron","TETX2 PROTEIN","PF01494(FAD_binding_3)",10,"ASP A 61;GLN A 192;ARG A 213;MET A 215;PHE A 224;ASN A 226;GLY A 236;PRO A 318;GLY A 321;MET A 375","CTC A1385\r"],["2Y6R_B_CTCB1385","2y6r","CTC","DB09093(Chlortetracycline)","Bacteroides thetaiotaomicron","TETX2 PROTEIN","None",8,"GLN B 192;ARG B 213;MET B 215;PHE B 224;GLY B 236;PRO B 318;GLY B 321;MET B 375","CTC B1385\r"],["2Y6R_C_CTCC1385","2y6r","CTC","DB09093(Chlortetracycline)","Bacteroides thetaiotaomicron","TETX2 PROTEIN","None",12,"ASP C 61;ASN C 190;GLN C 192;ARG C 213;MET C 215;PHE C 224;HIS C 234;GLY C 236;SER C 238;PRO C 318;GLY C 321;MET C 375","CTC C1385\r"],["2Y6R_D_CTCD1385","2y6r","CTC","DB09093(Chlortetracycline)","Bacteroides thetaiotaomicron","TETX2 PROTEIN","None",10,"ASP D 61;GLN D 192;ARG D 213;MET D 215;PHE D 224;HIS D 234;GLY D 236;SER D 238;PRO D 318;MET D 375","CTC D1385\r"],["3Q5P_A_TACA7101","3q5p","TAC","DB00759(Tetracycline)","Bacillus subtilis","MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR","PF06445(GyrI-like);PF13411(MerR_1)",12,"PRO A 144;VAL A 147;ASN A 149;TYR A 152;TYR A 170;ILE A 182;TYR A 187;PHE A 224;TYR A 229;GLU A 253;ILE A 255;TYR A 268","TAC A7101\r"],["4B3A_A_TACA222","4b3a","TAC","DB00759(Tetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR PROTEIN CLASS D","PF00440(TetR_N);PF02909(TetR_C)",12,"LEU A 60;HIS A 64;SER A 67;ASN A 82;PHE A 86;ARG A 104;PRO A 105;GLN A 109;VAL A 113;GLN A 116;ILE A 134;SER A 138","TAC A 222\r"],["4V2G_B_CTCB222","4v2g","CTC","DB09093(Chlortetracycline)","Escherichia coli","TETRACYCLINE REPRESSOR PROTEIN CLASS D","None;PF00440(TetR_N);PF02909(TetR_C)",14,"HIS B 64;SER B 67;ASN B 82;PHE B 86;HIS B 100;ARG B 104;PRO B 105;THR B 112;VAL B 113;GLN B 116;ILE B 134;SER B 138;LEU A 170;LEU A 174","CTC B 222\r"],["5TUI_B_CTCB405","5tui","CTC","DB09093(Chlortetracycline)","uncultured bacterium","TETRACYCLINE DESTRUCTASE TET(50)","None",17,"ASP B 47;ARG B 49;GLY B 94;PHE B 95;ARG B 96;GLU B 102;VAL B 181;LEU B 198;LEU B 205;THR B 207;GLY B 220;MET B 222;PRO B 296;GLY B 299;PHE B 344;VAL B 348;ILE B 371","CTC B 405\r"]]