DRUG BINDING INTERFACES MAPPED TO 'RIFABUTIN'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
2A68_C_RBTC8001 2a68 RBT

DB00615
(Rifabutin)
Thermus
thermophilus
DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN;
RNA POLYMERASE SIGMA
FACTOR RPOD
PF00140
(Sigma70_r1_2)
PF00562
(RNA_pol_Rpb2_6)
PF04539
(Sigma70_r3)
PF04542
(Sigma70_r2)
PF04545
(Sigma70_r4)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF10385
(RNA_pol_Rpb2_45)
11 ARG C 134
ASP F 323
GLN C 390
GLN C 393
PHE C 394
ASP C 396
HIS C 406
ARG C 409
SER C 411
PRO C 444
ILE C 452
RBT C8001
2A68_M_RBTM8002 2a68 RBT

DB00615
(Rifabutin)
Thermus
thermophilus
DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN;
RNA POLYMERASE SIGMA
FACTOR RPOD
no annotation 13 ARG M 134
ASP P 323
LYS P 325
GLN M 390
GLN M 393
PHE M 394
ASP M 396
HIS M 406
ARG M 409
SER M 411
PRO M 444
ILE M 452
ASN M 563
RBT M8002
4CP3_B_RBTB1129 4cp3 RBT

DB00615
(Rifabutin)
Homo sapiens B-CELL LYMPHOMA 6
PROTEIN
PF00651
(BTB)
no annotation
7 ASN A  21
ARG A  24
LEU A  25
ARG A  28
GLY B  55
TYR B  58
SER B  59
RBT B1129
6BEC_C_RBTC601 6bec RBT

DB00615
(Rifabutin)
Vaccinia virus SCAFFOLD PROTEIN D13 no annotation 12 VAL B  24
VAL A  24
GLN C  27
GLU A 165
PHE C 168
PHE B 168
PRO A 483
PRO C 483
ILE C 485
PHE B 486
PHE C 486
PHE A 486
RBT C 601