DRUG BINDING INTERFACES MAPPED TO 'NILOTINIB'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3CS9_A_NILA600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	22	LEU A 248 TYR A 253 VAL A 256 ALA A 269 LYS A 271 LYS A 285 GLU A 286 VAL A 289 MET A 290 ILE A 293 LEU A 298 VAL A 299 ILE A 313 THR A 315 PHE A 317 GLY A 321 PHE A 359 HIS A 361 LEU A 370 VAL A 379 ALA A 380 ASP A 381	NIL A 600
3CS9_B_NILB600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	21	LEU B 248 TYR B 253 VAL B 256 ALA B 269 LYS B 271 GLU B 286 VAL B 289 MET B 290 ILE B 293 LEU B 298 VAL B 299 ILE B 313 THR B 315 GLY B 321 PHE B 359 HIS B 361 LEU B 370 VAL B 379 ALA B 380 ASP B 381 PHE B 382	NIL B 600
3CS9_C_NILC600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	21	LEU C 248 TYR C 253 VAL C 256 ALA C 269 LYS C 271 GLU C 286 VAL C 289 MET C 290 ILE C 293 LEU C 298 VAL C 299 ILE C 313 THR C 315 PHE C 317 MET C 318 PHE C 359 HIS C 361 VAL C 379 ALA C 380 ASP C 381 PHE C 382	NIL C 600
3CS9_D_NILD600	3cs9	NIL DB04868 (Nilotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	18	LEU D 248 TYR D 253 VAL D 256 ALA D 269 LYS D 271 GLU D 286 VAL D 289 MET D 290 ILE D 293 LEU D 298 THR D 315 PHE D 317 GLY D 321 PHE D 359 HIS D 361 LEU D 370 ALA D 380 ASP D 381	NIL D 600
3GP0_A_NILA1	3gp0	NIL DB04868 (Nilotinib)	Homo sapiens	MITOGEN-ACTIVATED PROTEIN KINASE 11	PF00069 (Pkinase)	19	VAL A 38 ALA A 51 LYS A 53 ARG A 67 GLU A 71 LEU A 74 LEU A 75 VAL A 83 ILE A 84 LEU A 104 THR A 106 LEU A 108 MET A 109 HIS A 148 ALA A 157 ILE A 166 LEU A 167 ASP A 168 PHE A 169	NIL A 1
5MO4_A_NILA601	5mo4	NIL DB04868 (Nilotinib)	Homo sapiens	TYROSINE-PROTEIN KINASE ABL1	PF00017 (SH2) PF00018 (SH3_1) PF07714 (Pkinase_Tyr)	22	LEU A 267 TYR A 272 VAL A 275 ALA A 288 LYS A 290 GLU A 305 VAL A 308 MET A 309 ILE A 312 LEU A 317 VAL A 318 ILE A 332 ILE A 334 PHE A 336 MET A 337 GLY A 340 PHE A 378 HIS A 380 LEU A 389 ALA A 399 ASP A 400 PHE A 401	NIL A 601

[["3CS9_A_NILA600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",22,"LEU A 248;TYR A 253;VAL A 256;ALA A 269;LYS A 271;LYS A 285;GLU A 286;VAL A 289;MET A 290;ILE A 293;LEU A 298;VAL A 299;ILE A 313;THR A 315;PHE A 317;GLY A 321;PHE A 359;HIS A 361;LEU A 370;VAL A 379;ALA A 380;ASP A 381","NIL A 600\r"],["3CS9_B_NILB600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",21,"LEU B 248;TYR B 253;VAL B 256;ALA B 269;LYS B 271;GLU B 286;VAL B 289;MET B 290;ILE B 293;LEU B 298;VAL B 299;ILE B 313;THR B 315;GLY B 321;PHE B 359;HIS B 361;LEU B 370;VAL B 379;ALA B 380;ASP B 381;PHE B 382","NIL B 600\r"],["3CS9_C_NILC600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",21,"LEU C 248;TYR C 253;VAL C 256;ALA C 269;LYS C 271;GLU C 286;VAL C 289;MET C 290;ILE C 293;LEU C 298;VAL C 299;ILE C 313;THR C 315;PHE C 317;MET C 318;PHE C 359;HIS C 361;VAL C 379;ALA C 380;ASP C 381;PHE C 382","NIL C 600\r"],["3CS9_D_NILD600","3cs9","NIL","DB04868(Nilotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",18,"LEU D 248;TYR D 253;VAL D 256;ALA D 269;LYS D 271;GLU D 286;VAL D 289;MET D 290;ILE D 293;LEU D 298;THR D 315;PHE D 317;GLY D 321;PHE D 359;HIS D 361;LEU D 370;ALA D 380;ASP D 381","NIL D 600\r"],["3GP0_A_NILA1","3gp0","NIL","DB04868(Nilotinib)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 11","PF00069(Pkinase)",19,"VAL A  38;ALA A  51;LYS A  53;ARG A  67;GLU A  71;LEU A  74;LEU A  75;VAL A  83;ILE A  84;LEU A 104;THR A 106;LEU A 108;MET A 109;HIS A 148;ALA A 157;ILE A 166;LEU A 167;ASP A 168;PHE A 169","NIL A   1\r"],["5MO4_A_NILA601","5mo4","NIL","DB04868(Nilotinib)","Homo sapiens","TYROSINE-PROTEIN KINASE ABL1","PF00017(SH2);PF00018(SH3_1);PF07714(Pkinase_Tyr)",22,"LEU A 267;TYR A 272;VAL A 275;ALA A 288;LYS A 290;GLU A 305;VAL A 308;MET A 309;ILE A 312;LEU A 317;VAL A 318;ILE A 332;ILE A 334;PHE A 336;MET A 337;GLY A 340;PHE A 378;HIS A 380;LEU A 389;ALA A 399;ASP A 400;PHE A 401","NIL A 601\r"]]