DRUG BINDING INTERFACES MAPPED TO 'MITOXANTRONE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
2FUM_A_MIXA539	2fum	MIX DB01204 (Mitoxantrone)	Mycobacterium tuberculosis	PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB	PF00069 (Pkinase)	14	LEU A 17 GLY A 18 VAL A 25 ALA A 38 TYR A 94 VAL A 95 ASP A 102 ASP A 138 LYS A 140 ALA A 142 ASN A 143 MET A 145 MET A 155 ASP A 156	MIX A 539
2FUM_B_MIXB1539	2fum	MIX DB01204 (Mitoxantrone)	Mycobacterium tuberculosis	PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB	no annotation	12	LEU B 17 GLY B 18 VAL B 25 ALA B 38 MET B 92 TYR B 94 VAL B 95 LYS B 140 ASN B 143 MET B 145 MET B 155 ASP B 156	MIX B1539
2FUM_C_MIXC2539	2fum	MIX DB01204 (Mitoxantrone)	Mycobacterium tuberculosis	PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB	no annotation	13	LEU C 17 GLY C 18 VAL C 25 ALA C 38 MET C 92 TYR C 94 VAL C 95 THR C 99 ASP C 102 ASN C 143 MET C 145 MET C 155 ASP C 156	MIX C2539
2FUM_D_MIXD3539	2fum	MIX DB01204 (Mitoxantrone)	Mycobacterium tuberculosis	PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB	no annotation	15	LEU D 17 GLY D 18 GLY D 20 VAL D 25 ALA D 38 MET D 92 VAL D 95 VAL D 98 THR D 99 ASP D 138 LYS D 140 ASN D 143 MET D 145 MET D 155 ASP D 156	MIX D3539
4G0V_A_MIXA1301	4g0v	MIX DB01204 (Mitoxantrone)	Homo sapiens	DNA TOPOISOMERASE 2-BETA	PF00521 (DNA_topoisoIV) PF01751 (Toprim) PF16898 (TOPRIM_C)	7	ARG A 503 GLY A 504 ILE A 506 ASN A 520 GLU A 522 GLN A 778 MET A 782	MIX A1301
4G0V_D_MIXD101	4g0v	MIX DB01204 (Mitoxantrone)	; Homo sapiens	DNA TOPOISOMERASE 2-BETA	no annotation	6	ARG B 503 GLY B 504 ASN B 520 GLU B 522 GLN B 778 MET B 782	MIX D 101
4I41_A_MIXA500	4i41	MIX DB01204 (Mitoxantrone)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE PIM-1	PF00069 (Pkinase)	16	LEU A 44 PHE A 49 VAL A 52 ALA A 65 ILE A 104 LEU A 120 GLN A 127 ASP A 128 ASP A 131 ASP A 167 LYS A 169 GLU A 171 ASN A 172 LEU A 174 ILE A 185 ASP A 186	MIX A 500
4I41_A_MIXA501	4i41	MIX DB01204 (Mitoxantrone)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE PIM-1	PF00069 (Pkinase)	12	ILE A 133 THR A 134 LYS A 169 ASP A 170 THR A 204 VAL A 206 ASP A 234 ASP A 239 ILE A 240 GLU A 243 GLU A 247 ARG A 256	MIX A 501
6GH9_A_MIXA1003	6gh9	MIX DB01204 (Mitoxantrone)	Homo sapiens	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15	PF00443 (UCH)	5	ASN A 264 TYR A 855 GLY A 856 HIS A 862 ASP A 879	MIX A1003

[["2FUM_A_MIXA539","2fum","MIX","DB01204(Mitoxantrone)","Mycobacterium tuberculosis","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","PF00069(Pkinase)",14,"LEU A  17;GLY A  18;VAL A  25;ALA A  38;TYR A  94;VAL A  95;ASP A 102;ASP A 138;LYS A 140;ALA A 142;ASN A 143;MET A 145;MET A 155;ASP A 156","MIX A 539\r"],["2FUM_B_MIXB1539","2fum","MIX","DB01204(Mitoxantrone)","Mycobacterium tuberculosis","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","no annotation",12,"LEU B  17;GLY B  18;VAL B  25;ALA B  38;MET B  92;TYR B  94;VAL B  95;LYS B 140;ASN B 143;MET B 145;MET B 155;ASP B 156","MIX B1539\r"],["2FUM_C_MIXC2539","2fum","MIX","DB01204(Mitoxantrone)","Mycobacterium tuberculosis","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","no annotation",13,"LEU C  17;GLY C  18;VAL C  25;ALA C  38;MET C  92;TYR C  94;VAL C  95;THR C  99;ASP C 102;ASN C 143;MET C 145;MET C 155;ASP C 156","MIX C2539\r"],["2FUM_D_MIXD3539","2fum","MIX","DB01204(Mitoxantrone)","Mycobacterium tuberculosis","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","no annotation",15,"LEU D  17;GLY D  18;GLY D  20;VAL D  25;ALA D  38;MET D  92;VAL D  95;VAL D  98;THR D  99;ASP D 138;LYS D 140;ASN D 143;MET D 145;MET D 155;ASP D 156","MIX D3539\r"],["4G0V_A_MIXA1301","4g0v","MIX","DB01204(Mitoxantrone)","Homo sapiens","DNA TOPOISOMERASE 2-BETA","PF00521(DNA_topoisoIV);PF01751(Toprim);PF16898(TOPRIM_C)",7,"ARG A 503;GLY A 504;ILE A 506;ASN A 520;GLU A 522;GLN A 778;MET A 782","MIX A1301\r"],["4G0V_D_MIXD101","4g0v","MIX","DB01204(Mitoxantrone)",";Homo sapiens","DNA TOPOISOMERASE 2-BETA","no annotation",6,"ARG B 503;GLY B 504;ASN B 520;GLU B 522;GLN B 778;MET B 782","MIX D 101\r"],["4I41_A_MIXA500","4i41","MIX","DB01204(Mitoxantrone)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE PIM-1","PF00069(Pkinase)",16,"LEU A  44;PHE A  49;VAL A  52;ALA A  65;ILE A 104;LEU A 120;GLN A 127;ASP A 128;ASP A 131;ASP A 167;LYS A 169;GLU A 171;ASN A 172;LEU A 174;ILE A 185;ASP A 186","MIX A 500\r"],["4I41_A_MIXA501","4i41","MIX","DB01204(Mitoxantrone)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE PIM-1","PF00069(Pkinase)",12,"ILE A 133;THR A 134;LYS A 169;ASP A 170;THR A 204;VAL A 206;ASP A 234;ASP A 239;ILE A 240;GLU A 243;GLU A 247;ARG A 256","MIX A 501\r"],["6GH9_A_MIXA1003","6gh9","MIX","DB01204(Mitoxantrone)","Homo sapiens","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15","PF00443(UCH)",5,"ASN A 264;TYR A 855;GLY A 856;HIS A 862;ASP A 879","MIX A1003\r"]]