DRUG BINDING INTERFACES MAPPED TO 'LIOTHYRONINE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1BSX_A_T3A1	1bsx	T3 DB00279 (Liothyronine)	Homo sapiens	PROTEIN (THYROID HORMONE RECEPTOR BETA)	PF00104 (Hormone_recep)	14	ILE A 275 ILE A 276 ARG A 282 MET A 310 MET A 313 ARG A 316 ALA A 317 ARG A 320 LEU A 330 LEU A 346 ILE A 353 HIS A 435 MET A 442 PHE A 455	T3 A 1
1BSX_B_T3B2	1bsx	T3 DB00279 (Liothyronine)	Homo sapiens	PROTEIN (THYROID HORMONE RECEPTOR BETA)	no annotation	14	ILE B 275 ILE B 276 ARG B 282 MET B 310 MET B 313 ARG B 316 ALA B 317 ARG B 320 LEU B 330 LEU B 346 ILE B 353 HIS B 435 MET B 442 PHE B 455	T3 B 2
1SN5_C_T3C601	1sn5	T3 DB00279 (Liothyronine)	Sparus aurata	TRANSTHYRETIN	PF00576 (Transthyretin) no annotation	14	MET C 13 LYS C 15 LYS A 15 LEU A 17 LEU C 17 GLU C 54 GLU A 54 THR C 106 ALA A 108 ALA C 108 LEU A 110 LEU C 110 VAL A 121 VAL C 121	T3 C 601
1SN5_D_T3D602	1sn5	T3 DB00279 (Liothyronine)	Sparus aurata	TRANSTHYRETIN	no annotation	12	LYS B 15 LYS D 15 LEU B 17 LEU D 17 GLU D 54 GLU B 54 ALA D 108 ALA B 108 LEU D 110 LEU B 110 VAL B 121 VAL D 121	T3 D 602
1XZX_X_T3X500	1xzx	T3 DB00279 (Liothyronine)	Homo sapiens	THYROID HORMONE RECEPTOR BETA-1	PF00104 (Hormone_recep)	15	PHE X 272 ILE X 275 ILE X 276 ALA X 279 ARG X 282 MET X 310 MET X 313 ARG X 316 LEU X 330 ASN X 331 LEU X 346 ILE X 353 HIS X 435 MET X 442 PHE X 455	T3 X 500
2H77_A_T3A1	2h77	T3 DB00279 (Liothyronine)	Homo sapiens	THRA PROTEIN	PF00104 (Hormone_recep)	14	ILE A 221 ILE A 222 ALA A 225 ARG A 228 MET A 256 MET A 259 ARG A 262 ALA A 263 LEU A 276 SER A 277 LEU A 292 ILE A 299 HIS A 381 PHE A 401	T3 A 1
2H79_A_T3A1	2h79	T3 DB00279 (Liothyronine)	Homo sapiens	THRA PROTEIN	PF00104 (Hormone_recep)	14	ILE A 221 ILE A 222 ALA A 225 ARG A 228 MET A 256 MET A 259 ARG A 262 ALA A 263 LEU A 276 SER A 277 LEU A 292 ILE A 299 HIS A 381 PHE A 401	T3 A 1
2PIV_A_T3A933	2piv	T3 DB00279 (Liothyronine)	Homo sapiens	ANDROGEN RECEPTOR	PF00104 (Hormone_recep)	9	PRO A 671 ILE A 672 PHE A 673 GLY A 724 GLU A 829 ASN A 833 TYR A 834 GLU A 837 ARG A 840	T3 A 933
2PIW_A_T3A932	2piw	T3 DB00279 (Liothyronine)	Homo sapiens	ANDROGEN RECEPTOR	PF00104 (Hormone_recep)	6	LEU A 712 VAL A 716 LYS A 717 ILE A 737 MET A 894 ILE A 898	T3 A 932
2PIW_A_T3A933	2piw	T3 DB00279 (Liothyronine)	Homo sapiens	ANDROGEN RECEPTOR	PF00104 (Hormone_recep)	10	ILE A 672 PHE A 673 GLY A 724 ASN A 727 PHE A 826 GLU A 829 ASN A 833 TYR A 834 GLU A 837 ARG A 840	T3 A 933
3GWS_X_T3X500	3gws	T3 DB00279 (Liothyronine)	Homo sapiens	THYROID HORMONE RECEPTOR BETA	PF00104 (Hormone_recep)	14	ILE X 275 ILE X 276 ALA X 279 ARG X 282 MET X 310 MET X 313 ARG X 316 ALA X 317 LEU X 330 ASN X 331 LEU X 346 ILE X 353 HIS X 435 PHE X 455	T3 X 500
3UVV_A_T3A501	3uvv	T3 DB00279 (Liothyronine)	Gallus gallus	THYROID HORMONE RECEPTOR ALPHA	PF00104 (Hormone_recep)	15	ILE A 219 ILE A 220 ALA A 223 ARG A 226 MET A 254 MET A 257 ARG A 260 ALA A 261 LEU A 274 LEU A 285 LEU A 290 ILE A 297 HIS A 379 MET A 386 PHE A 399	T3 A 501
3VKX_A_T3A301	3vkx	T3 DB00279 (Liothyronine)	Homo sapiens	PROLIFERATING CELL NUCLEAR ANTIGEN	PF00705 (PCNA_N) PF02747 (PCNA_C)	6	MET A 40 LEU A 47 PRO A 129 GLN A 131 PRO A 234 TYR A 250	T3 A 301
4BVA_A_T3A1314	4bva	T3 DB00279 (Liothyronine)	Mus musculus	THIOMORPHOLINE-CARBO XYLATE DEHYDROGENASE	PF02423 (OCD_Mu_crystall)	12	ARG A 47 VAL A 49 PHE A 58 GLY A 60 VAL A 77 PHE A 79 HIS A 91 SER A 228 ARG A 229 PRO A 230 TRP A 232 GLU A 256	T3 A1314
4BVA_B_T3B1314	4bva	T3 DB00279 (Liothyronine)	Mus musculus	THIOMORPHOLINE-CARBO XYLATE DEHYDROGENASE	no annotation	12	ARG B 47 VAL B 49 PHE B 58 GLY B 60 VAL B 77 PHE B 79 HIS B 91 SER B 228 ARG B 229 PRO B 230 TRP B 232 GLU B 256	T3 B1314
4LNW_A_T3A501	4lnw	T3 DB00279 (Liothyronine)	Homo sapiens	THYROID HORMONE RECEPTOR ALPHA	PF00104 (Hormone_recep)	15	ILE A 221 ILE A 222 ALA A 225 ARG A 228 MET A 256 MET A 259 ARG A 262 ALA A 263 LEU A 276 SER A 277 LEU A 292 ILE A 299 HIS A 381 MET A 388 PHE A 401	T3 A 501
4LNW_A_T3A502	4lnw	T3 DB00279 (Liothyronine)	Homo sapiens	THYROID HORMONE RECEPTOR ALPHA	PF00104 (Hormone_recep)	8	SER A 326 ASP A 328 GLU A 339 GLN A 342 MET A 369 VAL A 371 THR A 372 ARG A 375	T3 A 502
4LNX_A_T3A502	4lnx	T3 DB00279 (Liothyronine)	Homo sapiens	THYROID HORMONE RECEPTOR ALPHA	PF00104 (Hormone_recep)	15	ILE A 221 ILE A 222 ALA A 225 ARG A 228 MET A 256 MET A 259 ARG A 262 ALA A 263 LEU A 276 SER A 277 LEU A 292 ILE A 299 HIS A 381 MET A 388 PHE A 401	T3 A 502
4ZO1_X_T3X500	4zo1	T3 DB00279 (Liothyronine)	Homo sapiens	THYROID HORMONE RECEPTOR BETA	PF00104 (Hormone_recep)	14	PHE X 272 ILE X 276 ALA X 279 ARG X 282 MET X 310 MET X 313 ARG X 316 ALA X 317 ARG X 320 LEU X 330 ASN X 331 HIS X 435 MET X 442 PHE X 455	T3 X 500

[["1BSX_A_T3A1","1bsx","T3","DB00279(Liothyronine)","Homo sapiens","PROTEIN (THYROID HORMONE RECEPTOR BETA)","PF00104(Hormone_recep)",14,"ILE A 275;ILE A 276;ARG A 282;MET A 310;MET A 313;ARG A 316;ALA A 317;ARG A 320;LEU A 330;LEU A 346;ILE A 353;HIS A 435;MET A 442;PHE A 455"," T3 A   1\r"],["1BSX_B_T3B2","1bsx","T3","DB00279(Liothyronine)","Homo sapiens","PROTEIN (THYROID HORMONE RECEPTOR BETA)","no annotation",14,"ILE B 275;ILE B 276;ARG B 282;MET B 310;MET B 313;ARG B 316;ALA B 317;ARG B 320;LEU B 330;LEU B 346;ILE B 353;HIS B 435;MET B 442;PHE B 455"," T3 B   2\r"],["1SN5_C_T3C601","1sn5","T3","DB00279(Liothyronine)","Sparus aurata","TRANSTHYRETIN","PF00576(Transthyretin);no annotation",14,"MET C  13;LYS C  15;LYS A  15;LEU A  17;LEU C  17;GLU C  54;GLU A  54;THR C 106;ALA A 108;ALA C 108;LEU A 110;LEU C 110;VAL A 121;VAL C 121"," T3 C 601\r"],["1SN5_D_T3D602","1sn5","T3","DB00279(Liothyronine)","Sparus aurata","TRANSTHYRETIN","no annotation",12,"LYS B  15;LYS D  15;LEU B  17;LEU D  17;GLU D  54;GLU B  54;ALA D 108;ALA B 108;LEU D 110;LEU B 110;VAL B 121;VAL D 121"," T3 D 602\r"],["1XZX_X_T3X500","1xzx","T3","DB00279(Liothyronine)","Homo sapiens","THYROID HORMONE RECEPTOR BETA-1","PF00104(Hormone_recep)",15,"PHE X 272;ILE X 275;ILE X 276;ALA X 279;ARG X 282;MET X 310;MET X 313;ARG X 316;LEU X 330;ASN X 331;LEU X 346;ILE X 353;HIS X 435;MET X 442;PHE X 455"," T3 X 500\r"],["2H77_A_T3A1","2h77","T3","DB00279(Liothyronine)","Homo sapiens","THRA PROTEIN","PF00104(Hormone_recep)",14,"ILE A 221;ILE A 222;ALA A 225;ARG A 228;MET A 256;MET A 259;ARG A 262;ALA A 263;LEU A 276;SER A 277;LEU A 292;ILE A 299;HIS A 381;PHE A 401"," T3 A   1\r"],["2H79_A_T3A1","2h79","T3","DB00279(Liothyronine)","Homo sapiens","THRA PROTEIN","PF00104(Hormone_recep)",14,"ILE A 221;ILE A 222;ALA A 225;ARG A 228;MET A 256;MET A 259;ARG A 262;ALA A 263;LEU A 276;SER A 277;LEU A 292;ILE A 299;HIS A 381;PHE A 401"," T3 A   1\r"],["2PIV_A_T3A933","2piv","T3","DB00279(Liothyronine)","Homo sapiens","ANDROGEN RECEPTOR","PF00104(Hormone_recep)",9,"PRO A 671;ILE A 672;PHE A 673;GLY A 724;GLU A 829;ASN A 833;TYR A 834;GLU A 837;ARG A 840"," T3 A 933\r"],["2PIW_A_T3A932","2piw","T3","DB00279(Liothyronine)","Homo sapiens","ANDROGEN RECEPTOR","PF00104(Hormone_recep)",6,"LEU A 712;VAL A 716;LYS A 717;ILE A 737;MET A 894;ILE A 898"," T3 A 932\r"],["2PIW_A_T3A933","2piw","T3","DB00279(Liothyronine)","Homo sapiens","ANDROGEN RECEPTOR","PF00104(Hormone_recep)",10,"ILE A 672;PHE A 673;GLY A 724;ASN A 727;PHE A 826;GLU A 829;ASN A 833;TYR A 834;GLU A 837;ARG A 840"," T3 A 933\r"],["3GWS_X_T3X500","3gws","T3","DB00279(Liothyronine)","Homo sapiens","THYROID HORMONE RECEPTOR BETA","PF00104(Hormone_recep)",14,"ILE X 275;ILE X 276;ALA X 279;ARG X 282;MET X 310;MET X 313;ARG X 316;ALA X 317;LEU X 330;ASN X 331;LEU X 346;ILE X 353;HIS X 435;PHE X 455"," T3 X 500\r"],["3UVV_A_T3A501","3uvv","T3","DB00279(Liothyronine)","Gallus gallus","THYROID HORMONE RECEPTOR ALPHA","PF00104(Hormone_recep)",15,"ILE A 219;ILE A 220;ALA A 223;ARG A 226;MET A 254;MET A 257;ARG A 260;ALA A 261;LEU A 274;LEU A 285;LEU A 290;ILE A 297;HIS A 379;MET A 386;PHE A 399"," T3 A 501\r"],["3VKX_A_T3A301","3vkx","T3","DB00279(Liothyronine)","Homo sapiens","PROLIFERATING CELL NUCLEAR ANTIGEN","PF00705(PCNA_N);PF02747(PCNA_C)",6,"MET A  40;LEU A  47;PRO A 129;GLN A 131;PRO A 234;TYR A 250"," T3 A 301\r"],["4BVA_A_T3A1314","4bva","T3","DB00279(Liothyronine)","Mus musculus","THIOMORPHOLINE-CARBOXYLATE DEHYDROGENASE","PF02423(OCD_Mu_crystall)",12,"ARG A  47;VAL A  49;PHE A  58;GLY A  60;VAL A  77;PHE A  79;HIS A  91;SER A 228;ARG A 229;PRO A 230;TRP A 232;GLU A 256"," T3 A1314\r"],["4BVA_B_T3B1314","4bva","T3","DB00279(Liothyronine)","Mus musculus","THIOMORPHOLINE-CARBOXYLATE DEHYDROGENASE","no annotation",12,"ARG B  47;VAL B  49;PHE B  58;GLY B  60;VAL B  77;PHE B  79;HIS B  91;SER B 228;ARG B 229;PRO B 230;TRP B 232;GLU B 256"," T3 B1314\r"],["4LNW_A_T3A501","4lnw","T3","DB00279(Liothyronine)","Homo sapiens","THYROID HORMONE RECEPTOR ALPHA","PF00104(Hormone_recep)",15,"ILE A 221;ILE A 222;ALA A 225;ARG A 228;MET A 256;MET A 259;ARG A 262;ALA A 263;LEU A 276;SER A 277;LEU A 292;ILE A 299;HIS A 381;MET A 388;PHE A 401"," T3 A 501\r"],["4LNW_A_T3A502","4lnw","T3","DB00279(Liothyronine)","Homo sapiens","THYROID HORMONE RECEPTOR ALPHA","PF00104(Hormone_recep)",8,"SER A 326;ASP A 328;GLU A 339;GLN A 342;MET A 369;VAL A 371;THR A 372;ARG A 375"," T3 A 502\r"],["4LNX_A_T3A502","4lnx","T3","DB00279(Liothyronine)","Homo sapiens","THYROID HORMONE RECEPTOR ALPHA","PF00104(Hormone_recep)",15,"ILE A 221;ILE A 222;ALA A 225;ARG A 228;MET A 256;MET A 259;ARG A 262;ALA A 263;LEU A 276;SER A 277;LEU A 292;ILE A 299;HIS A 381;MET A 388;PHE A 401"," T3 A 502\r"],["4ZO1_X_T3X500","4zo1","T3","DB00279(Liothyronine)","Homo sapiens","THYROID HORMONE RECEPTOR BETA","PF00104(Hormone_recep)",14,"PHE X 272;ILE X 276;ALA X 279;ARG X 282;MET X 310;MET X 313;ARG X 316;ALA X 317;ARG X 320;LEU X 330;ASN X 331;HIS X 435;MET X 442;PHE X 455"," T3 X 500\r"]]