DRUG BINDING INTERFACES MAPPED TO 'KETOCONAZOLE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

Filter list by:

DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1JIN_A_KTNA801	1jin	KTN DB01026 (Ketoconazole)	Saccharopolyspora erythraea	CYTOCHROME P450 107A1	PF00067 (p450)	11	SER A 59 PHE A 72 ALA A 74 TYR A 75 THR A 92 VAL A 237 LEU A 240 ALA A 241 ALA A 245 THR A 292 LEU A 391	KTN A 801
1JIP_A_KTNA801	1jip	KTN DB01026 (Ketoconazole)	Saccharopolyspora erythraea	CYTOCHROME P450 107A1	PF00067 (p450)	13	PHE A 72 ALA A 74 TYR A 75 GLY A 91 THR A 92 ILE A 174 LEU A 175 ARG A 185 VAL A 237 LEU A 240 ALA A 241 THR A 292 LEU A 391	KTN A 801
2JJP_A_KLNA413	2jjp	KLN DB01026 (Ketoconazole)	Saccharopolyspora erythraea	CYTOCHROME P450 113A1	PF00067 (p450)	12	HIS A 88 MET A 174 PRO A 177 ALA A 237 LEU A 240 ALA A 241 THR A 245 PHE A 288 GLN A 290 MET A 291 GLN A 292 ILE A 392	KLN A 413
2V0M_A_KLNA1500	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	PF00067 (p450)	11	PHE A 57 ARG A 105 SER A 119 LEU A 210 ILE A 301 PHE A 304 ALA A 305 MET A 371 ARG A 372 GLU A 374 LEU A 482	KLN A1500
2V0M_A_KLNA1501	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	PF00067 (p450)	10	PHE A 57 ASP A 76 ARG A 106 SER A 119 ILE A 120 PHE A 213 LEU A 221 THR A 224 ILE A 301 GLY A 481	KLN A1501
2V0M_B_KLNB1498	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	9	PHE B 57 ARG B 105 SER B 119 LEU B 210 ILE B 301 ALA B 305 GLU B 374 GLY B 481 LEU B 482	KLN B1498
2V0M_B_KLNB1499	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	7	PHE B 57 PHE B 108 SER B 119 ILE B 120 THR B 224 ILE B 301 GLY B 481	KLN B1499
2V0M_C_KLNC1498	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	12	PHE C 57 ARG C 105 SER C 119 LEU C 210 LEU C 211 PHE C 241 ILE C 301 ALA C 305 THR C 309 MET C 371 ARG C 372 GLU C 374	KLN C1498
2V0M_C_KLNC1499	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	7	PHE C 57 PHE C 108 SER C 119 LEU C 211 PHE C 241 ILE C 301 GLY C 481	KLN C1499
2V0M_D_KLND1498	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	11	ARG D 105 SER D 119 LEU D 210 ILE D 301 PHE D 304 ALA D 305 THR D 309 MET D 371 ARG D 372 GLU D 374 LEU D 482	KLN D1498
2V0M_D_KLND1499	2v0m	KLN DB01026 (Ketoconazole)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	5	PHE D 57 PHE D 108 SER D 119 PHE D 213 ILE D 301	KLN D1499
3LD6_A_KKKA602	3ld6	KKK DB01026 (Ketoconazole)	Homo sapiens	LANOSTEROL 14-ALPHA DEMETHYLASE	PF00067 (p450)	13	TYR A 131 LEU A 134 PHE A 139 TYR A 145 PHE A 234 TRP A 239 GLY A 307 ALA A 311 THR A 315 ILE A 377 ILE A 379 MET A 381 MET A 487	KKK A 602
3LD6_B_KKKB602	3ld6	KKK DB01026 (Ketoconazole)	Homo sapiens	LANOSTEROL 14-ALPHA DEMETHYLASE	no annotation	13	PHE B 105 TYR B 131 PHE B 139 TYR B 145 PHE B 234 TRP B 239 GLY B 307 ALA B 311 THR B 315 ILE B 377 ILE B 379 MET B 381 MET B 487	KKK B 602
3OZW_A_KKKA413	3ozw	KKK DB01026 (Ketoconazole)	Cupriavidus necator	FLAVOHEMOGLOBIN	PF00042 (Globin) PF00175 (NAD_binding_1) PF00970 (FAD_binding_6)	8	ILE A 25 TYR A 29 GLN A 50 GLN A 53 ALA A 56 LEU A 57 LEU A 102 PRO A 398	KKK A 413
3OZW_B_KKKB413	3ozw	KKK DB01026 (Ketoconazole)	Cupriavidus necator	FLAVOHEMOGLOBIN	no annotation	12	ILE B 25 TYR B 29 HIS B 47 GLN B 52 GLN B 53 ALA B 56 LEU B 57 HIS B 85 LEU B 102 ILE B 371 GLY B 397 PRO B 398	KKK B 413
5LI8_A_KKKA502	5li8	KKK DB01026 (Ketoconazole)	Mycobacterium tuberculosis	PUTATIVE CYTOCHROME P450 126	PF00067 (p450)	12	THR A 13 PRO A 46 PHE A 51 VAL A 94 ASN A 96 ALA A 253 SER A 302 LYS A 303 ARG A 304 TRP A 327 ASN A 399 ARG A 400	KKK A 502
6AYB_A_KKKA508	6ayb	KKK DB01026 (Ketoconazole)	Naegleria fowleri	CYP51, STEROL 14ALPHA-DEMETHYLASE	no annotation	14	PRO A 57 TYR A 107 PHE A 109 PHE A 114 TYR A 120 PRO A 213 PHE A 217 ALA A 289 ALA A 293 THR A 297 LEU A 358 ILE A 359 MET A 362 LEU A 467	KKK A 508

[["1JIN_A_KTNA801","1jin","KTN","DB01026(Ketoconazole)","Saccharopolyspora erythraea","CYTOCHROME P450 107A1","PF00067(p450)",11,"SER A  59;PHE A  72;ALA A  74;TYR A  75;THR A  92;VAL A 237;LEU A 240;ALA A 241;ALA A 245;THR A 292;LEU A 391","KTN A 801\r"],["1JIP_A_KTNA801","1jip","KTN","DB01026(Ketoconazole)","Saccharopolyspora erythraea","CYTOCHROME P450 107A1","PF00067(p450)",13,"PHE A  72;ALA A  74;TYR A  75;GLY A  91;THR A  92;ILE A 174;LEU A 175;ARG A 185;VAL A 237;LEU A 240;ALA A 241;THR A 292;LEU A 391","KTN A 801\r"],["2JJP_A_KLNA413","2jjp","KLN","DB01026(Ketoconazole)","Saccharopolyspora erythraea","CYTOCHROME P450 113A1","PF00067(p450)",12,"HIS A  88;MET A 174;PRO A 177;ALA A 237;LEU A 240;ALA A 241;THR A 245;PHE A 288;GLN A 290;MET A 291;GLN A 292;ILE A 392","KLN A 413\r"],["2V0M_A_KLNA1500","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","PF00067(p450)",11,"PHE A  57;ARG A 105;SER A 119;LEU A 210;ILE A 301;PHE A 304;ALA A 305;MET A 371;ARG A 372;GLU A 374;LEU A 482","KLN A1500\r"],["2V0M_A_KLNA1501","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","PF00067(p450)",10,"PHE A  57;ASP A  76;ARG A 106;SER A 119;ILE A 120;PHE A 213;LEU A 221;THR A 224;ILE A 301;GLY A 481","KLN A1501\r"],["2V0M_B_KLNB1498","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",9,"PHE B  57;ARG B 105;SER B 119;LEU B 210;ILE B 301;ALA B 305;GLU B 374;GLY B 481;LEU B 482","KLN B1498\r"],["2V0M_B_KLNB1499","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",7,"PHE B  57;PHE B 108;SER B 119;ILE B 120;THR B 224;ILE B 301;GLY B 481","KLN B1499\r"],["2V0M_C_KLNC1498","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",12,"PHE C  57;ARG C 105;SER C 119;LEU C 210;LEU C 211;PHE C 241;ILE C 301;ALA C 305;THR C 309;MET C 371;ARG C 372;GLU C 374","KLN C1498\r"],["2V0M_C_KLNC1499","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",7,"PHE C  57;PHE C 108;SER C 119;LEU C 211;PHE C 241;ILE C 301;GLY C 481","KLN C1499\r"],["2V0M_D_KLND1498","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",11,"ARG D 105;SER D 119;LEU D 210;ILE D 301;PHE D 304;ALA D 305;THR D 309;MET D 371;ARG D 372;GLU D 374;LEU D 482","KLN D1498\r"],["2V0M_D_KLND1499","2v0m","KLN","DB01026(Ketoconazole)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",5,"PHE D  57;PHE D 108;SER D 119;PHE D 213;ILE D 301","KLN D1499\r"],["3LD6_A_KKKA602","3ld6","KKK","DB01026(Ketoconazole)","Homo sapiens","LANOSTEROL 14-ALPHA DEMETHYLASE","PF00067(p450)",13,"TYR A 131;LEU A 134;PHE A 139;TYR A 145;PHE A 234;TRP A 239;GLY A 307;ALA A 311;THR A 315;ILE A 377;ILE A 379;MET A 381;MET A 487","KKK A 602\r"],["3LD6_B_KKKB602","3ld6","KKK","DB01026(Ketoconazole)","Homo sapiens","LANOSTEROL 14-ALPHA DEMETHYLASE","no annotation",13,"PHE B 105;TYR B 131;PHE B 139;TYR B 145;PHE B 234;TRP B 239;GLY B 307;ALA B 311;THR B 315;ILE B 377;ILE B 379;MET B 381;MET B 487","KKK B 602\r"],["3OZW_A_KKKA413","3ozw","KKK","DB01026(Ketoconazole)","Cupriavidus necator","FLAVOHEMOGLOBIN","PF00042(Globin);PF00175(NAD_binding_1);PF00970(FAD_binding_6)",8,"ILE A  25;TYR A  29;GLN A  50;GLN A  53;ALA A  56;LEU A  57;LEU A 102;PRO A 398","KKK A 413\r"],["3OZW_B_KKKB413","3ozw","KKK","DB01026(Ketoconazole)","Cupriavidus necator","FLAVOHEMOGLOBIN","no annotation",12,"ILE B  25;TYR B  29;HIS B  47;GLN B  52;GLN B  53;ALA B  56;LEU B  57;HIS B  85;LEU B 102;ILE B 371;GLY B 397;PRO B 398","KKK B 413\r"],["5LI8_A_KKKA502","5li8","KKK","DB01026(Ketoconazole)","Mycobacterium tuberculosis","PUTATIVE CYTOCHROME P450 126","PF00067(p450)",12,"THR A  13;PRO A  46;PHE A  51;VAL A  94;ASN A  96;ALA A 253;SER A 302;LYS A 303;ARG A 304;TRP A 327;ASN A 399;ARG A 400","KKK A 502\r"],["6AYB_A_KKKA508","6ayb","KKK","DB01026(Ketoconazole)","Naegleria fowleri","CYP51, STEROL 14ALPHA-DEMETHYLASE","no annotation",14,"PRO A  57;TYR A 107;PHE A 109;PHE A 114;TYR A 120;PRO A 213;PHE A 217;ALA A 289;ALA A 293;THR A 297;LEU A 358;ILE A 359;MET A 362;LEU A 467","KKK A 508\r"]]