DRUG BINDING INTERFACES MAPPED TO 'INDOMETHACIN'
DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1S2A_A_IMNA2001 | 1s2a | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 14 | TYR A 24LEU A 54TRP A 86HIS A 117SER A 118MET A 120GLU A 192TYR A 216SER A 217SER A 221GLN A 222TRP A 227TYR A 305PHE A 306 | IMN A2001 |
1Z9H_A_IMNA379 | 1z9h | IMN DB00328(Indomethacin) | Macacafascicularis | MEMBRANE-ASSOCIATEDPROSTAGLANDIN ESYNTHASE-2 | PF13417(GST_N_3) | 13 | TYR A 107THR A 109CYS A 110PRO A 111PRO A 134ILE A 246VAL A 250TYR A 251SER A 260TYR A 263ILE A 264VAL A 343LEU A 347 | IMN A 379 |
1Z9H_B_IMNB381 | 1z9h | IMN DB00328(Indomethacin) | Macacafascicularis | MEMBRANE-ASSOCIATEDPROSTAGLANDIN ESYNTHASE-2 | no annotation | 13 | TYR B 107THR B 109CYS B 110PRO B 111PRO B 134ILE B 246VAL B 250TYR B 251SER B 260TYR B 263ILE B 264VAL B 343LEU B 347 | IMN B 381 |
1Z9H_C_IMNC379 | 1z9h | IMN DB00328(Indomethacin) | Macacafascicularis | MEMBRANE-ASSOCIATEDPROSTAGLANDIN ESYNTHASE-2 | no annotation | 13 | TYR C 107THR C 109CYS C 110PRO C 111PRO C 134ILE C 246VAL C 250TYR C 251SER C 260TYR C 263ILE C 264VAL C 343LEU C 347 | IMN C 379 |
1Z9H_D_IMND476 | 1z9h | IMN DB00328(Indomethacin) | Macacafascicularis | MEMBRANE-ASSOCIATEDPROSTAGLANDIN ESYNTHASE-2 | no annotation | 13 | TYR D 107THR D 109CYS D 110PRO D 111PRO D 134ILE D 246VAL D 250TYR D 251SER D 260TYR D 263ILE D 264VAL D 343LEU D 347 | IMN D 476 |
2BXK_A_IMNA2001 | 2bxk | IMN DB00328(Indomethacin) | Homo sapiens | SERUM ALBUMIN | PF00273(Serum_albumin) | 8 | LYS A 199SER A 202PHE A 211TRP A 214ALA A 215ARG A 218LEU A 238ASP A 451 | IMN A2001 |
2BXM_A_IMNA2001 | 2bxm | IMN DB00328(Indomethacin) | Homo sapiens | SERUM ALBUMIN | PF00273(Serum_albumin) | 8 | LYS A 199SER A 202ALA A 210PHE A 211TRP A 214ALA A 215ARG A 218LEU A 238 | IMN A2001 |
2BXM_A_IMNA2002 | 2bxm | IMN DB00328(Indomethacin) | Homo sapiens | SERUM ALBUMIN | PF00273(Serum_albumin) | 11 | ARG A 114LEU A 115ILE A 142ARG A 145HIS A 146LEU A 154PHE A 157TYR A 161ARG A 186GLY A 189LYS A 190 | IMN A2002 |
2BXQ_A_IMNA2001 | 2bxq | IMN DB00328(Indomethacin) | Homo sapiens | SERUM ALBUMIN | PF00273(Serum_albumin) | 10 | LYS A 199SER A 202ALA A 210PHE A 211TRP A 214ALA A 215ARG A 218LEU A 219LEU A 238LEU A 481 | IMN A2001 |
2BXQ_A_IMNA2003 | 2bxq | IMN DB00328(Indomethacin) | Homo sapiens | SERUM ALBUMIN | PF00273(Serum_albumin) | 10 | ARG A 114LEU A 115ILE A 142ARG A 145HIS A 146PHE A 157TYR A 161ARG A 186GLY A 189LYS A 190 | IMN A2003 |
2DM6_A_IMNA1401 | 2dm6 | IMN DB00328(Indomethacin) | Cavia porcellus | NADP-DEPENDENTLEUKOTRIENE B412-HYDROXYDEHYDROGENASE | PF00107(ADH_zinc_N)PF16884(ADH_N_2)no annotation | 10 | TYR A 49ILE A 52ALA A 53ARG A 56TYR A 245PRO B 257GLU B 258ILE B 261TYR B 262ILE A 271 | IMN A1401 |
2OTH_A_IMNA301 | 2oth | IMN DB00328(Indomethacin) | Daboia russelii | PHOSPHOLIPASE A2VRV-PL-VIIIA | PF00068(Phospholip_A2_1) | 3 | ASP A 49TYR A 52LYS A 69 | IMN A 301 |
2ZB8_A_IMNA800 | 2zb8 | IMN DB00328(Indomethacin) | Homo sapiens | PROSTAGLANDINREDUCTASE 2 | PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 9 | TYR A 51CYS A 54THR A 60PHE A 99TYR A 100TYR A 259LEU A 288VAL A 289LEU A 290 | IMN A 800 |
3ADS_A_IMNA1 | 3ads | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | PF00104(Hormone_recep) | 10 | GLU A 259ARG A 280ILE A 281GLY A 284CYS A 285ARG A 288LEU A 330ILE A 341MET A 348MET A 364 | IMN A 1 |
3ADS_A_IMNA2 | 3ads | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | PF00104(Hormone_recep) | 18 | ILE A 281PHE A 282CYS A 285SER A 289HIS A 323ILE A 326TYR A 327LEU A 330LEU A 353LEU A 356PHE A 360PHE A 363MET A 364LYS A 367HIS A 449LEU A 453LEU A 469TYR A 473 | IMN A 2 |
3ADS_B_IMNB3 | 3ads | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | no annotation | 12 | ILE B 281GLY B 284CYS B 285ARG B 288SER B 289ALA B 292ILE B 326LEU B 330LEU B 333VAL B 339ILE B 341MET B 364 | IMN B 3 |
3ADX_A_IMNA2 | 3adx | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | PF00104(Hormone_recep) | 19 | ILE A 281PHE A 282CYS A 285GLN A 286SER A 289HIS A 323ILE A 326TYR A 327LEU A 330LEU A 353LEU A 356PHE A 360PHE A 363MET A 364LYS A 367HIS A 449LEU A 453LEU A 469TYR A 473 | IMN A 2 |
3ADX_B_IMNB3 | 3adx | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | no annotation | 13 | LEU B 228ILE B 281GLY B 284CYS B 285ARG B 288SER B 289ALA B 292ILE B 326LEU B 330LEU B 333VAL B 339ILE B 341MET B 364 | IMN B 3 |
3FO7_A_IMNA301 | 3fo7 | IMN DB00328(Indomethacin) | Daboia russelii | PHOSPHOLIPASE A2VRV-PL-VIIIA | PF00068(Phospholip_A2_1) | 5 | HIS A 48ASP A 49TYR A 52PRO A 68LYS A 69 | IMN A 301 |
3H1X_A_IMNA301 | 3h1x | IMN DB00328(Indomethacin) | Daboia russelii | PHOSPHOLIPASE A2VRV-PL-VIIIA | PF00068(Phospholip_A2_1) | 5 | HIS A 48ASP A 49TYR A 52PRO A 68LYS A 69 | IMN A 301 |
3IB1_A_IMNA701 | 3ib1 | IMN DB00328(Indomethacin) | Bos taurus | LACTOTRANSFERRIN | PF00405(Transferrin) | 4 | PRO A 429THR A 430GLY A 662THR A 663 | IMN A 701 |
3OGW_A_IMNA597 | 3ogw | IMN DB00328(Indomethacin) | Bos taurus | LACTOPEROXIDASE | PF03098(An_peroxidase) | 9 | GLN A 105HIS A 109PHE A 113GLU A 116PHE A 254ARG A 255GLU A 258PHE A 381GLN A 423 | IMN A 597 |
3UG8_A_IMNA2001 | 3ug8 | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 15 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117MET A 120ASN A 167GLU A 192TYR A 216SER A 217SER A 221TYR A 305PHE A 306PRO A 318TYR A 319 | IMN A2001 |
3UGR_A_IMNA2001 | 3ugr | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 19 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117SER A 118MET A 120ASN A 167GLU A 192TYR A 216SER A 217SER A 221GLN A 222TRP A 227TYR A 305PHE A 306PHE A 311PRO A 318TYR A 319 | IMN A2001 |
4COX_A_IMNA701 | 4cox | IMN DB00328(Indomethacin) | Mus musculus | CYCLOOXYGENASE-2 | PF00008(EGF)PF03098(An_peroxidase) | 13 | ARG A 120VAL A 349SER A 353TYR A 355LEU A 384TYR A 385TRP A 387MET A 522VAL A 523GLY A 526ALA A 527SER A 530LEU A 531 | IMN A 701 |
4COX_B_IMNB701 | 4cox | IMN DB00328(Indomethacin) | Mus musculus | CYCLOOXYGENASE-2 | no annotation | 13 | ARG B 120VAL B 349SER B 353TYR B 355LEU B 384TYR B 385TRP B 387MET B 522VAL B 523GLY B 526ALA B 527SER B 530LEU B 531 | IMN B 701 |
4COX_C_IMNC701 | 4cox | IMN DB00328(Indomethacin) | Mus musculus | CYCLOOXYGENASE-2 | no annotation | 14 | ARG C 120VAL C 349LEU C 352SER C 353TYR C 355LEU C 384TYR C 385TRP C 387MET C 522VAL C 523GLY C 526ALA C 527SER C 530LEU C 531 | IMN C 701 |
4COX_D_IMND701 | 4cox | IMN DB00328(Indomethacin) | Mus musculus | CYCLOOXYGENASE-2 | no annotation | 13 | ARG D 120VAL D 349SER D 353TYR D 355LEU D 384TYR D 385TRP D 387MET D 522VAL D 523GLY D 526ALA D 527SER D 530LEU D 531 | IMN D 701 |
4IK7_A_IMNA201 | 4ik7 | IMN DB00328(Indomethacin) | Homo sapiens | TRANSTHYRETIN | PF00576(Transthyretin) | 7 | MET A 13LYS A 15LEU A 17THR A 106ALA A 108THR A 119VAL A 121 | IMN A 201 |
4IK7_B_IMNB201 | 4ik7 | IMN DB00328(Indomethacin) | Homo sapiens | TRANSTHYRETIN | no annotation | 8 | LYS B 15LEU B 17THR B 106ALA B 108LEU B 110SER B 117THR B 119VAL B 121 | IMN B 201 |
4IKI_A_IMNA201 | 4iki | IMN DB00328(Indomethacin) | Homo sapiens | TRANSTHYRETIN | PF00576(Transthyretin) | 3 | LYS A 15LEU A 17ALA A 108 | IMN A 201 |
4IKI_B_IMNB201 | 4iki | IMN DB00328(Indomethacin) | Homo sapiens | TRANSTHYRETIN | no annotation | 6 | LYS B 15LEU B 17ALA B 108LEU B 110SER B 117THR B 119 | IMN B 201 |
4JQ4_A_IMNA401 | 4jq4 | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 | PF00248(Aldo_ket_red) | 10 | TYR A 24VAL A 54TYR A 55HIS A 117VAL A 128TYR A 216GLU A 224TRP A 227LEU A 306LEU A 308 | IMN A 401 |
4JQ4_B_IMNB401 | 4jq4 | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 | no annotation | 10 | TYR B 24TYR B 55HIS B 117VAL B 128ILE B 129ASN B 167TYR B 216TRP B 227LEU B 306LEU B 308 | IMN B 401 |
4KYK_B_IMNB300 | 4kyk | IMN DB00328(Indomethacin) | Mus musculus | LACTOYLGLUTATHIONELYASE | PF00903(Glyoxalase)no annotation | 12 | PHE A 63ALA A 65MET A 66PHE A 68LEU A 70PHE A 93LYS B 151GLY B 156LYS B 157MET B 158LEU B 161PHE B 163 | IMN B 300 |
4XUM_A_IMNA501 | 4xum | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | PF00104(Hormone_recep) | 13 | PHE A 282CYS A 285SER A 289HIS A 323ILE A 326LEU A 356PHE A 363MET A 364HIS A 449LEU A 453LEU A 465LEU A 469TYR A 473 | IMN A 501 |
4XUM_A_IMNA502 | 4xum | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | PF00104(Hormone_recep) | 7 | GLU A 259ILE A 281CYS A 285ARG A 288LEU A 330ILE A 341MET A 348 | IMN A 502 |
4XUM_B_IMNB501 | 4xum | IMN DB00328(Indomethacin) | Homo sapiens | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA | no annotation | 11 | GLY B 284CYS B 285ARG B 288SER B 289ALA B 292ILE B 326MET B 329LEU B 330LEU B 333ILE B 341MET B 348 | IMN B 501 |
4YIA_B_IMNB401 | 4yia | IMN DB00328(Indomethacin) | Homo sapiens | THYROXINE-BINDINGGLOBULIN | PF00079(Serpin) | 13 | SER A 23SER A 24GLN A 238LEU A 246LEU A 248SER A 266LEU A 269TRP A 272ASN A 273LEU A 276LEU B 376ARG B 378ARG B 381 | IMN B 401 |