DRUG BINDING INTERFACES MAPPED TO 'IBRUTINIB'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
4IFG_A_1E8A601	4ifg	1E8 DB09053 (Ibrutinib)	Toxoplasma gondii	CALMODULIN-DOMAIN PROTEIN KINASE 1	PF00069 (Pkinase) PF13499 (EF-hand_7)	14	GLY A 58 VAL A 65 ALA A 78 LYS A 80 MET A 112 LEU A 114 LEU A 126 TYR A 131 GLY A 134 GLU A 135 LEU A 181 ILE A 194 ASP A 195 LEU A 198	1E8 A 601
4RZ7_A_1E8A901	4rz7	1E8 DB09053 (Ibrutinib)	Plasmodium vivax	CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE	PF00027 (cNMP_binding) PF00069 (Pkinase)	10	ILE A 540 ALA A 561 LYS A 563 THR A 586 ILE A 595 PHE A 609 THR A 611 LEU A 613 VAL A 614 LEU A 664	1E8 A 901
5P9I_A_1E8A701	5p9i	1E8 DB09053 (Ibrutinib)	Homo sapiens	TYROSINE-PROTEIN KINASE BTK	PF07714 (Pkinase_Tyr)	17	LEU A 408 GLY A 411 VAL A 416 ALA A 428 LYS A 430 MET A 449 ILE A 472 THR A 474 TYR A 476 MET A 477 GLY A 480 CYS A 481 ASN A 484 LEU A 528 SER A 538 ASP A 539 PHE A 540	1E8 A 701
5YU9_A_1E8A1101	5yu9	1E8 DB09053 (Ibrutinib)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	no annotation	14	LEU A 718 GLY A 719 VAL A 726 ALA A 743 LYS A 745 MET A 766 LEU A 788 MET A 790 MET A 793 CYS A 797 ARG A 841 LEU A 844 THR A 854 ASP A 855	1E8 A1101
5YU9_B_1E8B1101	5yu9	1E8 DB09053 (Ibrutinib)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	no annotation	14	LEU B 718 GLY B 719 VAL B 726 ALA B 743 LYS B 745 MET B 766 LEU B 788 MET B 790 MET B 793 CYS B 797 ASP B 800 LEU B 844 THR B 854 ASP B 855	1E8 B1101
5YU9_C_1E8C1101	5yu9	1E8 DB09053 (Ibrutinib)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	no annotation	14	VAL C 726 ALA C 743 LYS C 745 MET C 766 LEU C 788 MET C 790 LEU C 792 MET C 793 GLY C 796 CYS C 797 ASP C 800 ARG C 841 THR C 854 ASP C 855	1E8 C1101
5YU9_D_1E8D1101	5yu9	1E8 DB09053 (Ibrutinib)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	no annotation	15	VAL D 726 ALA D 743 LYS D 745 MET D 766 LEU D 788 MET D 790 MET D 793 GLY D 796 CYS D 797 ASP D 800 LEU D 844 THR D 854 ASP D 855 LEU D 858 ARG B 962	1E8 D1101

[["4IFG_A_1E8A601","4ifg","1E8","DB09053(Ibrutinib)","Toxoplasma gondii","CALMODULIN-DOMAIN PROTEIN KINASE 1","PF00069(Pkinase);PF13499(EF-hand_7)",14,"GLY A  58;VAL A  65;ALA A  78;LYS A  80;MET A 112;LEU A 114;LEU A 126;TYR A 131;GLY A 134;GLU A 135;LEU A 181;ILE A 194;ASP A 195;LEU A 198","1E8 A 601\r"],["4RZ7_A_1E8A901","4rz7","1E8","DB09053(Ibrutinib)","Plasmodium vivax","CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE","PF00027(cNMP_binding);PF00069(Pkinase)",10,"ILE A 540;ALA A 561;LYS A 563;THR A 586;ILE A 595;PHE A 609;THR A 611;LEU A 613;VAL A 614;LEU A 664","1E8 A 901\r"],["5P9I_A_1E8A701","5p9i","1E8","DB09053(Ibrutinib)","Homo sapiens","TYROSINE-PROTEIN KINASE BTK","PF07714(Pkinase_Tyr)",17,"LEU A 408;GLY A 411;VAL A 416;ALA A 428;LYS A 430;MET A 449;ILE A 472;THR A 474;TYR A 476;MET A 477;GLY A 480;CYS A 481;ASN A 484;LEU A 528;SER A 538;ASP A 539;PHE A 540","1E8 A 701\r"],["5YU9_A_1E8A1101","5yu9","1E8","DB09053(Ibrutinib)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","no annotation",14,"LEU A 718;GLY A 719;VAL A 726;ALA A 743;LYS A 745;MET A 766;LEU A 788;MET A 790;MET A 793;CYS A 797;ARG A 841;LEU A 844;THR A 854;ASP A 855","1E8 A1101\r"],["5YU9_B_1E8B1101","5yu9","1E8","DB09053(Ibrutinib)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","no annotation",14,"LEU B 718;GLY B 719;VAL B 726;ALA B 743;LYS B 745;MET B 766;LEU B 788;MET B 790;MET B 793;CYS B 797;ASP B 800;LEU B 844;THR B 854;ASP B 855","1E8 B1101\r"],["5YU9_C_1E8C1101","5yu9","1E8","DB09053(Ibrutinib)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","no annotation",14,"VAL C 726;ALA C 743;LYS C 745;MET C 766;LEU C 788;MET C 790;LEU C 792;MET C 793;GLY C 796;CYS C 797;ASP C 800;ARG C 841;THR C 854;ASP C 855","1E8 C1101\r"],["5YU9_D_1E8D1101","5yu9","1E8","DB09053(Ibrutinib)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","no annotation",15,"VAL D 726;ALA D 743;LYS D 745;MET D 766;LEU D 788;MET D 790;MET D 793;GLY D 796;CYS D 797;ASP D 800;LEU D 844;THR D 854;ASP D 855;LEU D 858;ARG B 962","1E8 D1101\r"]]