DRUG BINDING INTERFACES MAPPED TO 'HALOFUGINONE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
4HVC_A_HFGA1602	4hvc	HFG DB04866 (Halofuginone)	Homo sapiens	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE	PF00587 (HGTP_anticodon) PF03129 (ProRS-C_1) PF09180 (tRNA-synt_2b)	16	HIS A1093 PHE A1097 GLU A1100 VAL A1101 PRO A1120 THR A1121 GLU A1123 ARG A1152 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 HIS A1242 SER A1272 GLY A1274	HFG A1602
4HVC_B_HFGB1602	4hvc	HFG DB04866 (Halofuginone)	Homo sapiens	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE	None	17	LEU B1087 HIS B1093 PHE B1097 GLU B1100 VAL B1101 PRO B1120 THR B1121 GLU B1123 ARG B1152 TRP B1169 GLU B1171 HIS B1173 PHE B1216 THR B1240 HIS B1242 SER B1272 GLY B1274	HFG B1602
4K88_A_HFGA602	4k88	HFG DB04866 (Halofuginone)	Homo sapiens	PROLINE--TRNA LIGASE	PF00587 (ProRS-C_1) PF03129 (tRNA-synt_2b) PF09180 (HGTP_anticodon)	12	PHE A 97 GLU A 100 VAL A 101 PRO A 120 THR A 121 GLU A 123 ARG A 152 TRP A 169 GLU A 171 PHE A 216 HIS A 242 SER A 272	HFG A 602
4OLF_A_HFGA802	4olf	HFG DB04866 (Halofuginone)	Plasmodium falciparum	PROLINE--TRNA LIGASE	PF00587 (tRNA-synt_2b) PF03129 (HGTP_anticodon) PF09180 (ProRS-C_1)	16	PHE A 335 GLU A 338 VAL A 339 PRO A 358 THR A 359 GLU A 361 ARG A 390 TRP A 407 GLU A 409 HIS A 411 PHE A 454 THR A 478 HIS A 480 SER A 508 TRP A 509 GLY A 510	HFG A 802
4Q15_A_HFGA803	4q15	HFG DB04866 (Halofuginone)	Plasmodium falciparum	PROLINE--TRNA LIGASE	PF00587 (HGTP_anticodon) PF03129 (ProRS-C_1) PF09180 (tRNA-synt_2b)	15	LEU A 325 PHE A 335 GLU A 338 VAL A 339 PRO A 358 THR A 359 GLU A 361 ARG A 390 TRP A 407 HIS A 411 PHE A 454 THR A 478 HIS A 480 SER A 508 GLY A 510	HFG A 803
4Q15_B_HFGB803	4q15	HFG DB04866 (Halofuginone)	Plasmodium falciparum	PROLINE--TRNA LIGASE	None	15	LEU B 325 PHE B 335 GLU B 338 VAL B 339 PRO B 358 THR B 359 GLU B 361 ARG B 390 TRP B 407 GLU B 409 PHE B 454 THR B 478 HIS B 480 SER B 508 GLY B 510	HFG B 803
4YDQ_A_HFGA802	4ydq	HFG DB04866 (Halofuginone)	Plasmodium falciparum	PROLINE--TRNA LIGASE	PF00587 (ProRS-C_1) PF03129 (tRNA-synt_2b) PF09180 (HGTP_anticodon)	16	LEU A 325 PHE A 335 GLU A 338 VAL A 339 PRO A 358 THR A 359 GLU A 361 ARG A 390 TRP A 407 GLU A 409 HIS A 411 PHE A 454 THR A 478 HIS A 480 SER A 508 GLY A 510	HFG A 802
4YDQ_B_HFGB802	4ydq	HFG DB04866 (Halofuginone)	Plasmodium falciparum	PROLINE--TRNA LIGASE	None	15	PHE B 335 GLU B 338 VAL B 339 PRO B 358 THR B 359 GLU B 361 ARG B 390 TRP B 407 GLU B 409 HIS B 411 PHE B 454 THR B 478 HIS B 480 SER B 508 GLY B 510	HFG B 802
5F9Z_A_HFGA702	5f9z	HFG DB04866 (Halofuginone)	Cryptosporidium parvum	AMINOACYL-TRNA SYNTHETASE	PF00587 (HGTP_anticodon) PF03129 (ProRS-C_1) PF09180 (tRNA-synt_2b)	16	LEU A 266 GLU A 274 GLY A 275 GLU A 279 VAL A 280 PRO A 299 THR A 300 GLU A 302 ARG A 331 TRP A 348 GLU A 350 PHE A 395 THR A 419 HIS A 421 SER A 449 GLY A 451	HFG A 702
5F9Z_B_HFGB703	5f9z	HFG DB04866 (Halofuginone)	Cryptosporidium parvum	AMINOACYL-TRNA SYNTHETASE	None	16	LEU B 266 PHE B 276 SER B 277 GLU B 279 VAL B 280 PRO B 299 THR B 300 GLU B 302 ARG B 331 TRP B 348 GLU B 350 PHE B 395 THR B 419 HIS B 421 SER B 449 GLY B 451	HFG B 703
5XIO_A_HFGA801	5xio	HFG DB04866 (Halofuginone)	Cryptosporidium parvum	PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE)	PF00587 (ProRS-C_1) PF03129 (tRNA-synt_2b) PF09180 (HGTP_anticodon)	15	PHE A 307 GLU A 310 VAL A 311 PRO A 330 THR A 331 GLU A 333 ARG A 362 TRP A 379 GLU A 381 HIS A 383 PHE A 426 THR A 450 HIS A 452 SER A 480 GLY A 482	HFG A 801
5XIO_B_HFGB802	5xio	HFG DB04866 (Halofuginone)	Cryptosporidium parvum	PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE)	None	13	PHE B 307 GLU B 310 VAL B 311 PRO B 330 THR B 331 GLU B 333 ARG B 362 TRP B 379 GLU B 381 HIS B 383 PHE B 426 THR B 450 HIS B 452	HFG B 802
5XIP_A_HFGA1003	5xip	HFG DB04866 (Halofuginone)	Eimeria tenella	PROLYL-TRNA SYNTHETASE, PUTATIVE	PF00587 (ProRS-C_1) PF03129 (tRNA-synt_2b) PF09180 (HGTP_anticodon)	15	LEU A 325 PHE A 335 GLU A 338 VAL A 339 PRO A 358 THR A 359 GLU A 361 ARG A 390 TRP A 407 HIS A 411 PHE A 454 THR A 478 HIS A 480 SER A 508 GLY A 510	HFG A1003
5XIP_B_HFGB1003	5xip	HFG DB04866 (Halofuginone)	Eimeria tenella	PROLYL-TRNA SYNTHETASE, PUTATIVE	None	12	PHE B 335 GLU B 338 VAL B 339 PRO B 358 THR B 359 GLU B 361 ARG B 390 TRP B 407 HIS B 411 PHE B 454 THR B 478 HIS B 480	HFG B1003
5XIP_C_HFGC1003	5xip	HFG DB04866 (Halofuginone)	Eimeria tenella	PROLYL-TRNA SYNTHETASE, PUTATIVE	None	14	LEU C 325 GLU C 338 VAL C 339 PRO C 358 THR C 359 GLU C 361 ARG C 390 TRP C 407 GLU C 409 HIS C 411 PHE C 454 THR C 478 HIS C 480 GLY C 510	HFG C1003
5XIP_D_HFGD1003	5xip	HFG DB04866 (Halofuginone)	Eimeria tenella	PROLYL-TRNA SYNTHETASE, PUTATIVE	None	13	LEU D 325 GLU D 338 VAL D 339 PRO D 358 THR D 359 GLU D 361 ARG D 390 TRP D 407 GLU D 409 PHE D 454 THR D 478 HIS D 480 TRP D 509	HFG D1003
5XIQ_A_HFGA1002	5xiq	HFG DB04866 (Halofuginone)	Toxoplasma gondii	PROLYL-TRNA SYNTHETASE (PRORS)	PF00587 (HGTP_anticodon) PF03129 (ProRS-C_1) PF09180 (tRNA-synt_2b)	16	LEU A 405 PHE A 415 GLU A 418 VAL A 419 PRO A 438 THR A 439 GLU A 441 ARG A 470 TRP A 487 GLU A 489 HIS A 491 PHE A 534 THR A 558 HIS A 560 SER A 588 GLY A 590	HFG A1002
5XIQ_B_HFGB1002	5xiq	HFG DB04866 (Halofuginone)	Toxoplasma gondii	PROLYL-TRNA SYNTHETASE (PRORS)	None	15	LEU B 405 PHE B 415 GLU B 418 VAL B 419 PRO B 438 THR B 439 GLU B 441 ARG B 470 TRP B 487 GLU B 489 HIS B 491 PHE B 534 THR B 558 HIS B 560 SER B 588	HFG B1002
5XIQ_C_HFGC1002	5xiq	HFG DB04866 (Halofuginone)	Toxoplasma gondii	PROLYL-TRNA SYNTHETASE (PRORS)	None	14	PHE C 415 GLU C 418 VAL C 419 PRO C 438 THR C 439 GLU C 441 ARG C 470 TRP C 487 GLU C 489 HIS C 491 PHE C 534 THR C 558 HIS C 560 SER C 588	HFG C1002
5XIQ_D_HFGD1002	5xiq	HFG DB04866 (Halofuginone)	Toxoplasma gondii	PROLYL-TRNA SYNTHETASE (PRORS)	None	15	LEU D 405 PHE D 415 GLU D 418 VAL D 419 PRO D 438 THR D 439 GLU D 441 ARG D 470 TRP D 487 GLU D 489 HIS D 491 PHE D 534 THR D 558 HIS D 560 GLY D 590	HFG D1002
6MN8_A_HFGA603	6mn8	HFG DB04866 (Halofuginone)	Onchocerca volvulus	UNCHARACTERIZED PROTEIN	PF00587 (HGTP_anticodon) PF03129 (tRNA-synt_2b)	16	LEU A 125 PHE A 135 GLU A 138 VAL A 139 PRO A 158 THR A 159 GLU A 161 ARG A 190 TRP A 207 GLU A 209 HIS A 211 THR A 278 HIS A 280 SER A 309 TRP A 310 GLY A 311	HFG A 603

[["4HVC_A_HFGA1602","4hvc","HFG","DB04866(Halofuginone)","Homo sapiens","BIFUNCTIONAL GLUTAMATE\/PROLINE--TRNA LIGASE","PF00587(HGTP_anticodon);PF03129(ProRS-C_1);PF09180(tRNA-synt_2b)",16,"HIS A1093;PHE A1097;GLU A1100;VAL A1101;PRO A1120;THR A1121;GLU A1123;ARG A1152;TRP A1169;GLU A1171;HIS A1173;PHE A1216;THR A1240;HIS A1242;SER A1272;GLY A1274","HFG A1602\r"],["4HVC_B_HFGB1602","4hvc","HFG","DB04866(Halofuginone)","Homo sapiens","BIFUNCTIONAL GLUTAMATE\/PROLINE--TRNA LIGASE","None",17,"LEU B1087;HIS B1093;PHE B1097;GLU B1100;VAL B1101;PRO B1120;THR B1121;GLU B1123;ARG B1152;TRP B1169;GLU B1171;HIS B1173;PHE B1216;THR B1240;HIS B1242;SER B1272;GLY B1274","HFG B1602\r"],["4K88_A_HFGA602","4k88","HFG","DB04866(Halofuginone)","Homo sapiens","PROLINE--TRNA LIGASE","PF00587(ProRS-C_1);PF03129(tRNA-synt_2b);PF09180(HGTP_anticodon)",12,"PHE A  97;GLU A 100;VAL A 101;PRO A 120;THR A 121;GLU A 123;ARG A 152;TRP A 169;GLU A 171;PHE A 216;HIS A 242;SER A 272","HFG A 602\r"],["4OLF_A_HFGA802","4olf","HFG","DB04866(Halofuginone)","Plasmodium falciparum","PROLINE--TRNA LIGASE","PF00587(tRNA-synt_2b);PF03129(HGTP_anticodon);PF09180(ProRS-C_1)",16,"PHE A 335;GLU A 338;VAL A 339;PRO A 358;THR A 359;GLU A 361;ARG A 390;TRP A 407;GLU A 409;HIS A 411;PHE A 454;THR A 478;HIS A 480;SER A 508;TRP A 509;GLY A 510","HFG A 802\r"],["4Q15_A_HFGA803","4q15","HFG","DB04866(Halofuginone)","Plasmodium falciparum","PROLINE--TRNA LIGASE","PF00587(HGTP_anticodon);PF03129(ProRS-C_1);PF09180(tRNA-synt_2b)",15,"LEU A 325;PHE A 335;GLU A 338;VAL A 339;PRO A 358;THR A 359;GLU A 361;ARG A 390;TRP A 407;HIS A 411;PHE A 454;THR A 478;HIS A 480;SER A 508;GLY A 510","HFG A 803\r"],["4Q15_B_HFGB803","4q15","HFG","DB04866(Halofuginone)","Plasmodium falciparum","PROLINE--TRNA LIGASE","None",15,"LEU B 325;PHE B 335;GLU B 338;VAL B 339;PRO B 358;THR B 359;GLU B 361;ARG B 390;TRP B 407;GLU B 409;PHE B 454;THR B 478;HIS B 480;SER B 508;GLY B 510","HFG B 803\r"],["4YDQ_A_HFGA802","4ydq","HFG","DB04866(Halofuginone)","Plasmodium falciparum","PROLINE--TRNA LIGASE","PF00587(ProRS-C_1);PF03129(tRNA-synt_2b);PF09180(HGTP_anticodon)",16,"LEU A 325;PHE A 335;GLU A 338;VAL A 339;PRO A 358;THR A 359;GLU A 361;ARG A 390;TRP A 407;GLU A 409;HIS A 411;PHE A 454;THR A 478;HIS A 480;SER A 508;GLY A 510","HFG A 802\r"],["4YDQ_B_HFGB802","4ydq","HFG","DB04866(Halofuginone)","Plasmodium falciparum","PROLINE--TRNA LIGASE","None",15,"PHE B 335;GLU B 338;VAL B 339;PRO B 358;THR B 359;GLU B 361;ARG B 390;TRP B 407;GLU B 409;HIS B 411;PHE B 454;THR B 478;HIS B 480;SER B 508;GLY B 510","HFG B 802\r"],["5F9Z_A_HFGA702","5f9z","HFG","DB04866(Halofuginone)","Cryptosporidium parvum","AMINOACYL-TRNA SYNTHETASE","PF00587(HGTP_anticodon);PF03129(ProRS-C_1);PF09180(tRNA-synt_2b)",16,"LEU A 266;GLU A 274;GLY A 275;GLU A 279;VAL A 280;PRO A 299;THR A 300;GLU A 302;ARG A 331;TRP A 348;GLU A 350;PHE A 395;THR A 419;HIS A 421;SER A 449;GLY A 451","HFG A 702\r"],["5F9Z_B_HFGB703","5f9z","HFG","DB04866(Halofuginone)","Cryptosporidium parvum","AMINOACYL-TRNA SYNTHETASE","None",16,"LEU B 266;PHE B 276;SER B 277;GLU B 279;VAL B 280;PRO B 299;THR B 300;GLU B 302;ARG B 331;TRP B 348;GLU B 350;PHE B 395;THR B 419;HIS B 421;SER B 449;GLY B 451","HFG B 703\r"],["5XIO_A_HFGA801","5xio","HFG","DB04866(Halofuginone)","Cryptosporidium parvum","PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE)","PF00587(ProRS-C_1);PF03129(tRNA-synt_2b);PF09180(HGTP_anticodon)",15,"PHE A 307;GLU A 310;VAL A 311;PRO A 330;THR A 331;GLU A 333;ARG A 362;TRP A 379;GLU A 381;HIS A 383;PHE A 426;THR A 450;HIS A 452;SER A 480;GLY A 482","HFG A 801\r"],["5XIO_B_HFGB802","5xio","HFG","DB04866(Halofuginone)","Cryptosporidium parvum","PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE)","None",13,"PHE B 307;GLU B 310;VAL B 311;PRO B 330;THR B 331;GLU B 333;ARG B 362;TRP B 379;GLU B 381;HIS B 383;PHE B 426;THR B 450;HIS B 452","HFG B 802\r"],["5XIP_A_HFGA1003","5xip","HFG","DB04866(Halofuginone)","Eimeria tenella","PROLYL-TRNA SYNTHETASE, PUTATIVE","PF00587(ProRS-C_1);PF03129(tRNA-synt_2b);PF09180(HGTP_anticodon)",15,"LEU A 325;PHE A 335;GLU A 338;VAL A 339;PRO A 358;THR A 359;GLU A 361;ARG A 390;TRP A 407;HIS A 411;PHE A 454;THR A 478;HIS A 480;SER A 508;GLY A 510","HFG A1003\r"],["5XIP_B_HFGB1003","5xip","HFG","DB04866(Halofuginone)","Eimeria tenella","PROLYL-TRNA SYNTHETASE, PUTATIVE","None",12,"PHE B 335;GLU B 338;VAL B 339;PRO B 358;THR B 359;GLU B 361;ARG B 390;TRP B 407;HIS B 411;PHE B 454;THR B 478;HIS B 480","HFG B1003\r"],["5XIP_C_HFGC1003","5xip","HFG","DB04866(Halofuginone)","Eimeria tenella","PROLYL-TRNA SYNTHETASE, PUTATIVE","None",14,"LEU C 325;GLU C 338;VAL C 339;PRO C 358;THR C 359;GLU C 361;ARG C 390;TRP C 407;GLU C 409;HIS C 411;PHE C 454;THR C 478;HIS C 480;GLY C 510","HFG C1003\r"],["5XIP_D_HFGD1003","5xip","HFG","DB04866(Halofuginone)","Eimeria tenella","PROLYL-TRNA SYNTHETASE, PUTATIVE","None",13,"LEU D 325;GLU D 338;VAL D 339;PRO D 358;THR D 359;GLU D 361;ARG D 390;TRP D 407;GLU D 409;PHE D 454;THR D 478;HIS D 480;TRP D 509","HFG D1003\r"],["5XIQ_A_HFGA1002","5xiq","HFG","DB04866(Halofuginone)","Toxoplasma gondii","PROLYL-TRNA SYNTHETASE (PRORS)","PF00587(HGTP_anticodon);PF03129(ProRS-C_1);PF09180(tRNA-synt_2b)",16,"LEU A 405;PHE A 415;GLU A 418;VAL A 419;PRO A 438;THR A 439;GLU A 441;ARG A 470;TRP A 487;GLU A 489;HIS A 491;PHE A 534;THR A 558;HIS A 560;SER A 588;GLY A 590","HFG A1002\r"],["5XIQ_B_HFGB1002","5xiq","HFG","DB04866(Halofuginone)","Toxoplasma gondii","PROLYL-TRNA SYNTHETASE (PRORS)","None",15,"LEU B 405;PHE B 415;GLU B 418;VAL B 419;PRO B 438;THR B 439;GLU B 441;ARG B 470;TRP B 487;GLU B 489;HIS B 491;PHE B 534;THR B 558;HIS B 560;SER B 588","HFG B1002\r"],["5XIQ_C_HFGC1002","5xiq","HFG","DB04866(Halofuginone)","Toxoplasma gondii","PROLYL-TRNA SYNTHETASE (PRORS)","None",14,"PHE C 415;GLU C 418;VAL C 419;PRO C 438;THR C 439;GLU C 441;ARG C 470;TRP C 487;GLU C 489;HIS C 491;PHE C 534;THR C 558;HIS C 560;SER C 588","HFG C1002\r"],["5XIQ_D_HFGD1002","5xiq","HFG","DB04866(Halofuginone)","Toxoplasma gondii","PROLYL-TRNA SYNTHETASE (PRORS)","None",15,"LEU D 405;PHE D 415;GLU D 418;VAL D 419;PRO D 438;THR D 439;GLU D 441;ARG D 470;TRP D 487;GLU D 489;HIS D 491;PHE D 534;THR D 558;HIS D 560;GLY D 590","HFG D1002\r"],["6MN8_A_HFGA603","6mn8","HFG","DB04866(Halofuginone)","Onchocerca volvulus","UNCHARACTERIZED PROTEIN","PF00587(HGTP_anticodon);PF03129(tRNA-synt_2b)",16,"LEU A 125;PHE A 135;GLU A 138;VAL A 139;PRO A 158;THR A 159;GLU A 161;ARG A 190;TRP A 207;GLU A 209;HIS A 211;THR A 278;HIS A 280;SER A 309;TRP A 310;GLY A 311","HFG A 603\r"]]