DRUG BINDING INTERFACES MAPPED TO 'FLUDARABINE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1PK9_A_2FAA306	1pk9	2FA DB01073 (Fludarabine)	Escherichia coli	PURINE NUCLEOSIDE PHOSPHORYLASE	PF01048 (PNP_UDP_1)	10	MET A 64 ARG A 87 SER A 90 GLY A 92 VAL A 178 GLU A 179 MET A 180 GLU A 181 SER A 203 ASP A 204	2FA A 306
1PK9_B_2FAB307	1pk9	2FA DB01073 (Fludarabine)	Escherichia coli	PURINE NUCLEOSIDE PHOSPHORYLASE	no annotation	9	MET B 64 ARG B 87 SER B 90 GLY B 92 GLU B 179 MET B 180 GLU B 181 SER B 203 ASP B 204	2FA B 307
1PK9_C_2FAC308	1pk9	2FA DB01073 (Fludarabine)	Escherichia coli	PURINE NUCLEOSIDE PHOSPHORYLASE	no annotation	11	MET C 64 ARG C 87 SER C 90 GLY C 92 VAL C 178 GLU C 179 MET C 180 GLU C 181 SER C 203 ASP C 204 ILE C 206	2FA C 308
1Z35_A_2FAA300	1z35	2FA DB01073 (Fludarabine)	Trichomonas vaginalis	PURINE NUCLEOSIDE PHOSPHORYLASE	PF01048 (PNP_UDP_1)	10	MET A 64 ARG A 87 THR A 90 GLY A 92 THR A 156 VAL A 178 GLU A 179 MET A 180 GLU A 181 SER A 203	2FA A 300
2PKK_A_2FAA501	2pkk	2FA DB01073 (Fludarabine)	Mycobacterium tuberculosis	ADENOSINE KINASE	PF00294 (PfkB)	16	SER A 8 ALA A 10 ASP A 12 GLY A 47 GLY A 48 VAL A 49 ASN A 52 PHE A 102 PHE A 116 MET A 121 ALA A 146 GLN A 172 GLN A 173 GLY A 254 ASP A 257 THR A 293	2FA A 501
2ZJ0_A_2FAA500	2zj0	2FA DB01073 (Fludarabine)	Mycobacterium tuberculosis	ADENOSYLHOMOCYSTEINA SE	PF00670 (AdoHcyase_NAD) PF05221 (AdoHcyase)	17	LEU A 68 HIS A 69 THR A 71 GLN A 73 THR A 74 ASP A 156 GLU A 218 THR A 219 LYS A 248 ASP A 252 HIS A 363 LEU A 407 LEU A 410 GLY A 415 HIS A 416 MET A 421 PHE A 425	2FA A 500
2ZJ0_B_2FAB500	2zj0	2FA DB01073 (Fludarabine)	Mycobacterium tuberculosis	ADENOSYLHOMOCYSTEINA SE	no annotation	17	LEU B 68 HIS B 69 THR B 71 GLN B 73 THR B 74 ASP B 156 GLU B 218 THR B 219 LYS B 248 ASP B 252 HIS B 363 LEU B 407 LEU B 410 GLY B 415 HIS B 416 MET B 421 PHE B 425	2FA B 500
2ZJ0_C_2FAC500	2zj0	2FA DB01073 (Fludarabine)	Mycobacterium tuberculosis	ADENOSYLHOMOCYSTEINA SE	no annotation	17	LEU C 68 HIS C 69 THR C 71 GLN C 73 THR C 74 ASP C 156 GLU C 218 THR C 219 LYS C 248 ASP C 252 HIS C 363 LEU C 407 LEU C 410 GLY C 415 HIS C 416 MET C 421 PHE C 425	2FA C 500
2ZJ0_D_2FAD500	2zj0	2FA DB01073 (Fludarabine)	Mycobacterium tuberculosis	ADENOSYLHOMOCYSTEINA SE	no annotation	16	LEU D 68 HIS D 69 THR D 71 GLN D 73 THR D 74 ASP D 156 GLU D 218 THR D 219 LYS D 248 ASP D 252 HIS D 363 LEU D 410 GLY D 415 HIS D 416 MET D 421 PHE D 425	2FA D 500
4DAN_A_2FAA301	4dan	2FA DB01073 (Fludarabine)	Bacillus subtilis	PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE	PF01048 (PNP_UDP_1) no annotation	13	HIS B 4 ARG B 43 MET A 64 ARG A 87 SER A 90 GLY A 92 VAL A 177 GLU A 178 MET A 179 GLU A 180 SER A 202 ASP A 203 VAL A 205	2FA A 301
4DAN_B_2FAB301	4dan	2FA DB01073 (Fludarabine)	Bacillus subtilis	PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE	PF01048 (PNP_UDP_1) no annotation	12	HIS A 4 ARG A 43 ARG B 87 SER B 90 GLY B 92 VAL B 177 GLU B 178 MET B 179 GLU B 180 SER B 202 ASP B 203 VAL B 205	2FA B 301
4DC3_B_2FAB401	4dc3	2FA DB01073 (Fludarabine)	Schistosoma mansoni	ADENOSINE KINASE	no annotation	17	ASN B 14 LEU B 16 ASP B 18 ILE B 38 LEU B 40 GLY B 63 GLY B 64 ALA B 65 ASN B 68 VAL B 123 MET B 134 THR B 136 LEU B 138 PHE B 169 ASN B 298 GLY B 299 ASP B 302	2FA B 401
4UBE_A_2FAA401	4ube	2FA DB01073 (Fludarabine)	Mycobacterium bovis	ADENOSINE KINASE	PF00294 (PfkB)	16	SER A 8 ALA A 10 ASP A 12 GLY A 47 GLY A 48 VAL A 49 ASN A 52 PHE A 102 PHE A 116 MET A 121 ALA A 146 GLN A 172 GLN A 173 GLY A 254 ASP A 257 THR A 293	2FA A 401

[["1PK9_A_2FAA306","1pk9","2FA","DB01073(Fludarabine)","Escherichia coli","PURINE NUCLEOSIDE PHOSPHORYLASE","PF01048(PNP_UDP_1)",10,"MET A  64;ARG A  87;SER A  90;GLY A  92;VAL A 178;GLU A 179;MET A 180;GLU A 181;SER A 203;ASP A 204","2FA A 306\r"],["1PK9_B_2FAB307","1pk9","2FA","DB01073(Fludarabine)","Escherichia coli","PURINE NUCLEOSIDE PHOSPHORYLASE","no annotation",9,"MET B  64;ARG B  87;SER B  90;GLY B  92;GLU B 179;MET B 180;GLU B 181;SER B 203;ASP B 204","2FA B 307\r"],["1PK9_C_2FAC308","1pk9","2FA","DB01073(Fludarabine)","Escherichia coli","PURINE NUCLEOSIDE PHOSPHORYLASE","no annotation",11,"MET C  64;ARG C  87;SER C  90;GLY C  92;VAL C 178;GLU C 179;MET C 180;GLU C 181;SER C 203;ASP C 204;ILE C 206","2FA C 308\r"],["1Z35_A_2FAA300","1z35","2FA","DB01073(Fludarabine)","Trichomonas vaginalis","PURINE NUCLEOSIDE PHOSPHORYLASE","PF01048(PNP_UDP_1)",10,"MET A  64;ARG A  87;THR A  90;GLY A  92;THR A 156;VAL A 178;GLU A 179;MET A 180;GLU A 181;SER A 203","2FA A 300\r"],["2PKK_A_2FAA501","2pkk","2FA","DB01073(Fludarabine)","Mycobacterium tuberculosis","ADENOSINE KINASE","PF00294(PfkB)",16,"SER A   8;ALA A  10;ASP A  12;GLY A  47;GLY A  48;VAL A  49;ASN A  52;PHE A 102;PHE A 116;MET A 121;ALA A 146;GLN A 172;GLN A 173;GLY A 254;ASP A 257;THR A 293","2FA A 501\r"],["2ZJ0_A_2FAA500","2zj0","2FA","DB01073(Fludarabine)","Mycobacterium tuberculosis","ADENOSYLHOMOCYSTEINASE","PF00670(AdoHcyase_NAD);PF05221(AdoHcyase)",17,"LEU A  68;HIS A  69;THR A  71;GLN A  73;THR A  74;ASP A 156;GLU A 218;THR A 219;LYS A 248;ASP A 252;HIS A 363;LEU A 407;LEU A 410;GLY A 415;HIS A 416;MET A 421;PHE A 425","2FA A 500\r"],["2ZJ0_B_2FAB500","2zj0","2FA","DB01073(Fludarabine)","Mycobacterium tuberculosis","ADENOSYLHOMOCYSTEINASE","no annotation",17,"LEU B  68;HIS B  69;THR B  71;GLN B  73;THR B  74;ASP B 156;GLU B 218;THR B 219;LYS B 248;ASP B 252;HIS B 363;LEU B 407;LEU B 410;GLY B 415;HIS B 416;MET B 421;PHE B 425","2FA B 500\r"],["2ZJ0_C_2FAC500","2zj0","2FA","DB01073(Fludarabine)","Mycobacterium tuberculosis","ADENOSYLHOMOCYSTEINASE","no annotation",17,"LEU C  68;HIS C  69;THR C  71;GLN C  73;THR C  74;ASP C 156;GLU C 218;THR C 219;LYS C 248;ASP C 252;HIS C 363;LEU C 407;LEU C 410;GLY C 415;HIS C 416;MET C 421;PHE C 425","2FA C 500\r"],["2ZJ0_D_2FAD500","2zj0","2FA","DB01073(Fludarabine)","Mycobacterium tuberculosis","ADENOSYLHOMOCYSTEINASE","no annotation",16,"LEU D  68;HIS D  69;THR D  71;GLN D  73;THR D  74;ASP D 156;GLU D 218;THR D 219;LYS D 248;ASP D 252;HIS D 363;LEU D 410;GLY D 415;HIS D 416;MET D 421;PHE D 425","2FA D 500\r"],["4DAN_A_2FAA301","4dan","2FA","DB01073(Fludarabine)","Bacillus subtilis","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","PF01048(PNP_UDP_1);no annotation",13,"HIS B   4;ARG B  43;MET A  64;ARG A  87;SER A  90;GLY A  92;VAL A 177;GLU A 178;MET A 179;GLU A 180;SER A 202;ASP A 203;VAL A 205","2FA A 301\r"],["4DAN_B_2FAB301","4dan","2FA","DB01073(Fludarabine)","Bacillus subtilis","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","PF01048(PNP_UDP_1);no annotation",12,"HIS A   4;ARG A  43;ARG B  87;SER B  90;GLY B  92;VAL B 177;GLU B 178;MET B 179;GLU B 180;SER B 202;ASP B 203;VAL B 205","2FA B 301\r"],["4DC3_B_2FAB401","4dc3","2FA","DB01073(Fludarabine)","Schistosoma mansoni","ADENOSINE KINASE","no annotation",17,"ASN B  14;LEU B  16;ASP B  18;ILE B  38;LEU B  40;GLY B  63;GLY B  64;ALA B  65;ASN B  68;VAL B 123;MET B 134;THR B 136;LEU B 138;PHE B 169;ASN B 298;GLY B 299;ASP B 302","2FA B 401\r"],["4UBE_A_2FAA401","4ube","2FA","DB01073(Fludarabine)","Mycobacterium bovis","ADENOSINE KINASE","PF00294(PfkB)",16,"SER A   8;ALA A  10;ASP A  12;GLY A  47;GLY A  48;VAL A  49;ASN A  52;PHE A 102;PHE A 116;MET A 121;ALA A 146;GLN A 172;GLN A 173;GLY A 254;ASP A 257;THR A 293","2FA A 401\r"]]