DRUG BINDING INTERFACES MAPPED TO 'EDETIC ACID'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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All hits from Homo Sapiens
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1NNF_A_EDTA400
1nnf
EDT
DB00974(EdeticAcid)
Haemophilusinfluenzae
IRON-UTILIZATIONPERIPLASMIC PROTEIN
PF01547(SBP_bac_1)
11
GLN A 9GLU A 57ARG A 101SER A 139ALA A 141LYS A 174ASN A 175ASN A 193TYR A 195TYR A 196ARG A 262
EDT A 400
1ZLQ_A_EDTA1513
1zlq
EDT
DB00974(EdeticAcid)
Escherichia coli
NICKEL-BINDINGPERIPLASMIC PROTEIN
PF00496(SBP_bac_5)
9
TYR A 22MET A 27ARG A 97TRP A 100ARG A 137TRP A 398TYR A 402HIS A 416THR A 490
EDT A1513
1ZLQ_B_EDTB1511
1zlq
EDT
DB00974(EdeticAcid)
Escherichia coli
NICKEL-BINDINGPERIPLASMIC PROTEIN
None
8
TYR B 22MET B 27ARG B 97TRP B 100ARG B 137TRP B 398TYR B 402THR B 490
EDT B1511
2AXN_A_EDTA737
2axn
EDT
DB00974(EdeticAcid)
Homo sapiens
6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 3(6PF-2-K/FRU-2,6-P2ASEBRAIN/PLACENTA-TYPEISOZYME) (IPFK-2)[INCLUDES: 6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC3.1.3.46)]
PF00300(6PF2K)PF01591(His_Phos_1)
13
PRO A 43LYS A 47THR A 48ASN A 69GLY A 71ARG A 74ARG A 75PHE A 87ARG A 98ALA A 125THR A 126ARG A 189TYR A 193
EDT A 737
3L7K_A_EDTA739
3l7k
EDT
DB00974(EdeticAcid)
Staphylococcusepidermidis
TEICHOIC ACIDBIOSYNTHESIS PROTEINF
NonePF04464(Glyphos_transf)
5
LEU A 323ARG B 324ARG A 324LYS B 327LYS A 327
EDT A 739
3L7K_D_EDTD735
3l7k
EDT
DB00974(EdeticAcid)
Staphylococcusepidermidis
TEICHOIC ACIDBIOSYNTHESIS PROTEINF
None
4
ARG D 324ARG C 324LYS D 327LYS C 327
EDT D 735
3L7M_A_EDTA738
3l7m
EDT
DB00974(EdeticAcid)
Staphylococcusepidermidis
TEICHOIC ACIDBIOSYNTHESIS PROTEINF
NonePF04464(Glyphos_transf)
5
LEU A 323ARG B 324ARG A 324LYS B 327LYS A 327
EDT A 738
3L7M_D_EDTD735
3l7m
EDT
DB00974(EdeticAcid)
Staphylococcusepidermidis
TEICHOIC ACIDBIOSYNTHESIS PROTEINF
None
4
ARG D 324ARG C 324LYS D 327LYS C 327
EDT D 735
3RNJ_A_EDTA1
3rnj
EDT
DB00974(EdeticAcid)
Homo sapiens
BRAIN-SPECIFICANGIOGENESISINHIBITOR1-ASSOCIATED PROTEIN2
PF14604(SH3_9)
4
LYS A 380ARG A 433LEU A 435ASP A 436
EDT A 1
3T8N_D_EDTD135
3t8n
EDT
DB00974(EdeticAcid)
Pseudomonasputida
STEROIDDELTA-ISOMERASE
None
11
THR D 71THR F 71GLY D 72GLY F 72PRO F 73PRO D 73ARG D 75ARG F 75PRO D 85PRO F 85ASP F 100
EDT D 135
3WFA_A_EDTA802
3wfa
EDT
DB00974(EdeticAcid)
Bacteroidesthetaiotaomicron
ALPHA-GLUCOSIDASE
NonePF10566(GH97_N)PF14508(GH97_C)PF14509(Glyco_hydro_97)
5
TYR B 407ARG B 449ASN A 488TYR A 492LYS A 495
EDT A 802
3WFA_B_EDTB802
3wfa
EDT
DB00974(EdeticAcid)
Bacteroidesthetaiotaomicron
ALPHA-GLUCOSIDASE
NonePF10566(GH97_N)PF14508(GH97_C)PF14509(Glyco_hydro_97)
6
ASP B 250TYR A 407ARG A 449ASN B 488TYR B 492LYS B 495
EDT B 802
4OES_A_EDTA601
4oes
EDT
DB00974(EdeticAcid)
Brucella suis
NIKA PROTEIN
PF00496(SBP_bac_5)
6
TYR A 20MET A 25TRP A 98ARG A 135TRP A 396TYR A 400
EDT A 601
5JHD_E_EDTE301
5jhd
EDT
DB00974(EdeticAcid)
Homo sapiens
BETA-2-MICROGLOBULIN;TCRBETA CHAIN
NonePF07654(V-set)PF07686(C1-set)
8
TYR E 49LYS E 59SER E 67THR E 79ARG G 81THR E 81PRO G 90ILE G 92
EDT E 301
5JHD_J_EDTJ301
5jhd
EDT
DB00974(EdeticAcid)
Homo sapiens
TCRBETA CHAIN
None
5
TYR J 49LYS J 59GLU J 64GLY J 65SER J 67
EDT J 301
5L8D_A_EDTA609
5l8d
EDT
DB00974(EdeticAcid)
Escherichia coli
NICKEL-BINDINGPERIPLASMIC PROTEIN
PF00496(SBP_bac_5)
8
TYR A 22MET A 27ARG A 97TRP A 100ARG A 137TRP A 398TYR A 402THR A 490
EDT A 609
5MWU_A_EDTA609
5mwu
EDT
DB00974(EdeticAcid)
Escherichia coli
NICKEL-BINDINGPERIPLASMIC PROTEIN
PF00496(SBP_bac_5)
8
TYR A 22MET A 27ARG A 97TRP A 100ARG A 137TRP A 398TYR A 402THR A 490
EDT A 609
5UIG_A_EDTA501
5uig
EDT
DB00974(EdeticAcid)
Escherichia coli;Homo sapiens
ADENOSINE RECEPTORA2A,SOLUBLECYTOCHROMEB562,ADENOSINERECEPTOR A2A
PF00001(Cytochrom_B562)PF07361(7tm_1)
6
ASN A 39THR A 41ASN A 42ARG A 102ILE A 292GLU A 294
EDT A 501
5UWC_G_EDTG407
5uwc
EDT
DB00974(EdeticAcid)
Homo sapiens
INTERLEUKIN-3RECEPTOR SUBUNITALPHA
PF09240(IL6Ra-bind)
5
TRP G 113HIS G 115SER G 121LYS G 155ARG G 166
EDT G 407
6BTX_A_EDTA503
6btx
EDT
DB00974(EdeticAcid)
Bdellovibriobacteriovorus
SOLUTE CARRIERFAMILY 39(IRON-REGULATEDTRANSPORTER)
PF06963(FPN1)
7
TRP A 254SER A 256SER A 259HIS A 261GLY A 262ARG A 348LEU A 351
EDT A 503
6EID_A_EDTA1111
6eid
EDT
DB00974(EdeticAcid)
Chlamydomonasreinhardtii
ARCHAEAL-TYPE OPSIN2
PF01036(Bac_rhodopsin)
4
GLN A 49ASN A 53PHE A 98TYR A 243
EDT A1111
[["1NNF_A_EDTA400","1nnf","EDT","DB00974(Edetic Acid)","Haemophilus influenzae","IRON-UTILIZATION PERIPLASMIC PROTEIN","PF01547(SBP_bac_1)",11,"GLN A 9;GLU A 57;ARG A 101;SER A 139;ALA A 141;LYS A 174;ASN A 175;ASN A 193;TYR A 195;TYR A 196;ARG A 262","EDT A 400\r"],["1ZLQ_A_EDTA1513","1zlq","EDT","DB00974(Edetic Acid)","Escherichia coli","NICKEL-BINDING PERIPLASMIC PROTEIN","PF00496(SBP_bac_5)",9,"TYR A 22;MET A 27;ARG A 97;TRP A 100;ARG A 137;TRP A 398;TYR A 402;HIS A 416;THR A 490","EDT A1513\r"],["1ZLQ_B_EDTB1511","1zlq","EDT","DB00974(Edetic Acid)","Escherichia coli","NICKEL-BINDING PERIPLASMIC PROTEIN","None",8,"TYR B 22;MET B 27;ARG B 97;TRP B 100;ARG B 137;TRP B 398;TYR B 402;THR B 490","EDT B1511\r"],["2AXN_A_EDTA737","2axn","EDT","DB00974(Edetic Acid)","Homo sapiens","6-PHOSPHOFRUCTO-2-KINASE\/FRUCTOSE-2,6-BIPHOSPHATASE 3 (6PF-2-K\/FRU- 2,6-P2ASE BRAIN\/PLACENTA-TYPE ISOZYME) (IPFK-2) [INCLUDES: 6- PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105); FRUCTOSE-2,6-BISPHOSPHATASE (EC 3.1.3.46)]","PF00300(6PF2K);PF01591(His_Phos_1)",13,"PRO A 43;LYS A 47;THR A 48;ASN A 69;GLY A 71;ARG A 74;ARG A 75;PHE A 87;ARG A 98;ALA A 125;THR A 126;ARG A 189;TYR A 193","EDT A 737\r"],["3L7K_A_EDTA739","3l7k","EDT","DB00974(Edetic Acid)","Staphylococcus epidermidis","TEICHOIC ACID BIOSYNTHESIS PROTEIN F","None;PF04464(Glyphos_transf)",5,"LEU A 323;ARG B 324;ARG A 324;LYS B 327;LYS A 327","EDT A 739\r"],["3L7K_D_EDTD735","3l7k","EDT","DB00974(Edetic Acid)","Staphylococcus epidermidis","TEICHOIC ACID BIOSYNTHESIS PROTEIN F","None",4,"ARG D 324;ARG C 324;LYS D 327;LYS C 327","EDT D 735\r"],["3L7M_A_EDTA738","3l7m","EDT","DB00974(Edetic Acid)","Staphylococcus epidermidis","TEICHOIC ACID BIOSYNTHESIS PROTEIN F","None;PF04464(Glyphos_transf)",5,"LEU A 323;ARG B 324;ARG A 324;LYS B 327;LYS A 327","EDT A 738\r"],["3L7M_D_EDTD735","3l7m","EDT","DB00974(Edetic Acid)","Staphylococcus epidermidis","TEICHOIC ACID BIOSYNTHESIS PROTEIN F","None",4,"ARG D 324;ARG C 324;LYS D 327;LYS C 327","EDT D 735\r"],["3RNJ_A_EDTA1","3rnj","EDT","DB00974(Edetic Acid)","Homo sapiens","BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2","PF14604(SH3_9)",4,"LYS A 380;ARG A 433;LEU A 435;ASP A 436","EDT A 1\r"],["3T8N_D_EDTD135","3t8n","EDT","DB00974(Edetic Acid)","Pseudomonas putida","STEROID DELTA-ISOMERASE","None",11,"THR D 71;THR F 71;GLY D 72;GLY F 72;PRO F 73;PRO D 73;ARG D 75;ARG F 75;PRO D 85;PRO F 85;ASP F 100","EDT D 135\r"],["3WFA_A_EDTA802","3wfa","EDT","DB00974(Edetic Acid)","Bacteroides thetaiotaomicron","ALPHA-GLUCOSIDASE","None;PF10566(GH97_N);PF14508(GH97_C);PF14509(Glyco_hydro_97)",5,"TYR B 407;ARG B 449;ASN A 488;TYR A 492;LYS A 495","EDT A 802\r"],["3WFA_B_EDTB802","3wfa","EDT","DB00974(Edetic Acid)","Bacteroides thetaiotaomicron","ALPHA-GLUCOSIDASE","None;PF10566(GH97_N);PF14508(GH97_C);PF14509(Glyco_hydro_97)",6,"ASP B 250;TYR A 407;ARG A 449;ASN B 488;TYR B 492;LYS B 495","EDT B 802\r"],["4OES_A_EDTA601","4oes","EDT","DB00974(Edetic Acid)","Brucella suis","NIKA PROTEIN","PF00496(SBP_bac_5)",6,"TYR A 20;MET A 25;TRP A 98;ARG A 135;TRP A 396;TYR A 400","EDT A 601\r"],["5JHD_E_EDTE301","5jhd","EDT","DB00974(Edetic Acid)","Homo sapiens","BETA-2-MICROGLOBULIN;TCRBETA CHAIN","None;PF07654(V-set);PF07686(C1-set)",8,"TYR E 49;LYS E 59;SER E 67;THR E 79;ARG G 81;THR E 81;PRO G 90;ILE G 92","EDT E 301\r"],["5JHD_J_EDTJ301","5jhd","EDT","DB00974(Edetic Acid)","Homo sapiens","TCRBETA CHAIN","None",5,"TYR J 49;LYS J 59;GLU J 64;GLY J 65;SER J 67","EDT J 301\r"],["5L8D_A_EDTA609","5l8d","EDT","DB00974(Edetic Acid)","Escherichia coli","NICKEL-BINDING PERIPLASMIC PROTEIN","PF00496(SBP_bac_5)",8,"TYR A 22;MET A 27;ARG A 97;TRP A 100;ARG A 137;TRP A 398;TYR A 402;THR A 490","EDT A 609\r"],["5MWU_A_EDTA609","5mwu","EDT","DB00974(Edetic Acid)","Escherichia coli","NICKEL-BINDING PERIPLASMIC PROTEIN","PF00496(SBP_bac_5)",8,"TYR A 22;MET A 27;ARG A 97;TRP A 100;ARG A 137;TRP A 398;TYR A 402;THR A 490","EDT A 609\r"],["5UIG_A_EDTA501","5uig","EDT","DB00974(Edetic Acid)","Escherichia coli;Homo sapiens","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","PF00001(Cytochrom_B562);PF07361(7tm_1)",6,"ASN A 39;THR A 41;ASN A 42;ARG A 102;ILE A 292;GLU A 294","EDT A 501\r"],["5UWC_G_EDTG407","5uwc","EDT","DB00974(Edetic Acid)","Homo sapiens","INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA","PF09240(IL6Ra-bind)",5,"TRP G 113;HIS G 115;SER G 121;LYS G 155;ARG G 166","EDT G 407\r"],["6BTX_A_EDTA503","6btx","EDT","DB00974(Edetic Acid)","Bdellovibrio bacteriovorus","SOLUTE CARRIER FAMILY 39 (IRON-REGULATED TRANSPORTER)","PF06963(FPN1)",7,"TRP A 254;SER A 256;SER A 259;HIS A 261;GLY A 262;ARG A 348;LEU A 351","EDT A 503\r"],["6EID_A_EDTA1111","6eid","EDT","DB00974(Edetic Acid)","Chlamydomonas reinhardtii","ARCHAEAL-TYPE OPSIN 2","PF01036(Bac_rhodopsin)",4,"GLN A 49;ASN A 53;PHE A 98;TYR A 243","EDT A1111\r"]]