DRUG BINDING INTERFACES MAPPED TO 'DB09114'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1KB9_A_PCFA514 1kb9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B;
CYTOCHROME C1, HEME
PROTEIN;
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I;
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT
PF00032
(Cytochrome_B)
PF00033
(Cytochrom_B_C)
PF00355
(UCR_TM)
PF02921
(Rieske)
PF00675
(Peptidase_M16_C)
PF05193
(Peptidase_M16)
PF02167
(Cytochrom_C1)
8 VAL E  60
MET E  63
SER E  67
HIS C 222
ILE C 226
PHE C 227
LYS D 291
SER A 450
PCF A 514
2AZQ_A_PCFA954 2azq PCF

DB09114
(Colfosceril
palmitate)
Pseudomonas
putida
CATECHOL
1,2-DIOXYGENASE
PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N)
9 THR A  40
LEU A  43
GLU A  53
HIS A  56
ALA A  57
TYR A  60
LEU A  61
GLU A 206
LEU A 210
PCF A 954
2YGN_A_PCFA1179 2ygn PCF

DB09114
(Colfosceril
palmitate)
Homo sapiens WNT INHIBITORY
FACTOR 1
PF02019
(WIF)
17 LEU A  36
ILE A  40
LEU A  48
ILE A  49
ILE A  55
MET A  63
PHE A  66
ARG A  76
MET A  77
PRO A  78
ILE A  80
MET A  87
PHE A  89
VAL A 152
VAL A 154
VAL A 156
PHE A 173
PCF A1179
2YGO_A_PCFA1213 2ygo PCF

DB09114
(Colfosceril
palmitate)
Homo sapiens WNT INHIBITORY
FACTOR 1
PF02019
(WIF)
18 LEU A  38
ILE A  40
LEU A  48
ILE A  49
ILE A  55
ILE A  57
MET A  63
PHE A  66
ARG A  76
MET A  77
PRO A  78
ILE A  80
MET A  87
PHE A  89
VAL A 152
VAL A 154
VAL A 156
PHE A 173
PCF A1213
2YGP_A_PCFA1213 2ygp PCF

DB09114
(Colfosceril
palmitate)
Homo sapiens WNT INHIBITORY
FACTOR 1
PF02019
(WIF)
21 LEU A  38
ILE A  40
LEU A  48
ILE A  49
ILE A  55
ILE A  57
PHE A  66
ARG A  76
TRP A  77
PRO A  78
ILE A  80
MET A  87
PHE A  89
TRP A  91
PHE A 138
PHE A 150
VAL A 152
VAL A 154
VAL A 156
PRO A 168
PHE A 173
PCF A1213
2YGQ_A_PCFA1275 2ygq PCF

DB09114
(Colfosceril
palmitate)
Homo sapiens WNT INHIBITORY
FACTOR 1
PF02019
(WIF)
PF12661
(hEGF)
14 LEU A  38
ILE A  40
LEU A  48
ILE A  57
MET A  77
PRO A  78
ILE A  80
PRO A  81
MET A  87
PHE A  89
PHE A 103
PHE A 138
VAL A 152
VAL A 154
PCF A1275
5VKQ_A_PCFA1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
6 ILE A1271
ILE A1416
LEU A1420
PHE A1422
HIS A1423
PHE B1452
PCF A1801
5VKQ_A_PCFA1803 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
10 HIS D1492
ILE D1494
ASN D1495
GLU D1498
TYR A1528
TYR A1532
LYS A1535
ILE A1536
ILE A1540
LEU A1543
PCF A1803
5VKQ_A_PCFA1804 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
5 TRP A1394
THR A1396
ASN B1467
TRP B1529
LEU B1533
PCF A1804
5VKQ_A_PCFA1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 SER D1319
THR D1324
PHE A1486
VAL A1489
HIS A1492
PRO A1493
ILE A1494
PCF A1805
5VKQ_A_PCFA1807 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 GLY A1363
LEU A1364
LEU A1410
ILE A1433
GLY A1434
LEU A1437
ILE B1540
PCF A1807
5VKQ_A_PCFA1808 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
5 LEU D1425
LEU A1437
LYS A1438
ALA A1441
LEU A1444
PCF A1808
5VKQ_B_PCFB1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 TRP B1394
THR B1396
ASN C1467
TRP C1529
LEU C1533
PCF B1801
5VKQ_B_PCFB1802 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 SER A1319
THR A1324
PHE B1486
VAL B1489
HIS B1492
PRO B1493
ILE B1494
PCF B1802
5VKQ_B_PCFB1804 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 8 GLY B1363
LEU B1364
LEU B1410
VAL B1414
ILE B1433
GLY B1434
LEU B1437
ILE C1540
PCF B1804
5VKQ_B_PCFB1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
5 LEU A1425
LEU B1437
LYS B1438
ALA B1441
LEU B1444
PCF B1805
5VKQ_B_PCFB1806 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 6 ILE B1271
ILE B1416
LEU B1420
PHE B1422
HIS B1423
PHE C1452
PCF B1806
5VKQ_B_PCFB1808 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
10 HIS A1492
ILE A1494
ASN A1495
GLU A1498
TYR B1528
TYR B1532
LYS B1535
ILE B1536
ILE B1540
LEU B1543
PCF B1808
5VKQ_C_PCFC1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 9 HIS B1492
ILE B1494
GLU B1498
TYR C1528
TYR C1532
LYS C1535
ILE C1536
ILE C1540
LEU C1543
PCF C1801
5VKQ_C_PCFC1802 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 TRP C1394
THR C1396
ASN D1467
TRP D1529
LEU D1533
PCF C1802
5VKQ_C_PCFC1803 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 8 SER B1319
THR B1324
PHE C1452
PHE C1486
VAL C1489
HIS C1492
PRO C1493
ILE C1494
PCF C1803
5VKQ_C_PCFC1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 9 GLY C1363
LEU C1364
LEU C1410
VAL C1414
ILE C1433
GLY C1434
LEU C1437
PHE D1454
ILE D1540
PCF C1805
5VKQ_C_PCFC1806 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 LEU B1425
LEU C1437
LYS C1438
ALA C1441
LEU C1444
PCF C1806
5VKQ_C_PCFC1807 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 6 ILE C1271
ILE C1416
LEU C1420
PHE C1422
HIS C1423
PHE D1452
PCF C1807
5VKQ_D_PCFD1801 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 10 HIS C1492
ILE C1494
ASN C1495
GLU C1498
TYR D1528
TYR D1532
LYS D1535
ILE D1536
ILE D1540
LEU D1543
PCF D1801
5VKQ_D_PCFD1802 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
4 TRP D1394
THR D1396
ASN A1467
LEU A1533
PCF D1802
5VKQ_D_PCFD1803 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 7 SER C1319
THR C1324
PHE D1486
VAL D1489
HIS D1492
PRO D1493
ILE D1494
PCF D1803
5VKQ_D_PCFD1805 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
7 GLY D1363
LEU D1364
LEU D1410
ILE D1433
GLY D1434
LEU D1437
ILE A1540
PCF D1805
5VKQ_D_PCFD1806 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None 5 LEU C1425
LEU D1437
LYS D1438
ALA D1441
LEU D1444
PCF D1806
5VKQ_D_PCFD1807 5vkq PCF

DB09114
(Colfosceril
palmitate)
Drosophila
melanogaster
NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L
None
PF00023
(Ank)
PF00520
(Ank_2)
PF12796
(Ank_2)
PF13637
(Ank_2)
6 ILE D1271
ILE D1416
LEU D1420
PHE D1422
HIS D1423
PHE A1452
PCF D1807
6GIQ_I_PCFI101 6giq PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL;
CYTOCHROME B-C1
COMPLEX SUBUNIT 9;
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
PF00115
(Peptidase_M16)
PF00675
(Peptidase_M16_C)
PF05193
(COX1)
PF00355
(COX4)
PF02921
(UCR_TM)
PF02936
(Rieske)
PF05365
(UCR_UQCRX_QCR9)
9 ASN I  14
VAL I  18
ILE I  21
TYR E  57
GLY E  64
SER E  68
ASP A 428
SER A 453
MET A 455
PCF I 101
6GIQ_T_PCFT101 6giq PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL;
CYTOCHROME B-C1
COMPLEX SUBUNIT 9;
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
None 8 ASN T  14
VAL T  18
TYR P  57
GLY P  64
SER P  68
ASP L 428
SER L 453
MET L 455
PCF T 101
6HU9_C_PCFC607 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B;
CYTOCHROME B-C1
COMPLEX SUBUNIT 7;
CYTOCHROME B-C1
COMPLEX SUBUNIT 8
PF00032
(COX3)
PF00033
(Cytochrom_B_C)
PF00510
(Cytochrome_B)
PF02238
(UCR_14kD)
PF02271
(COX7a)
PF02935
(UcrQ)
PF02939
(COX7C)
13 TRP C  29
LEU G  41
GLN H  55
GLU G  82
PHE C  94
MET C  97
ALA C  98
TYR C 102
TYR C 103
THR C 317
PHE C 326
PHE C 327
VAL C 330
PCF C 607
6HU9_E_PCFE202 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL;
CYTOCHROME C OXIDASE
SUBUNIT 1
PF00115
(Peptidase_M16)
PF00675
(Peptidase_M16_C)
PF05193
(COX1)
PF00355
(COX4)
PF02921
(UCR_TM)
PF02936
(Rieske)
8 GLN a  46
ALA e 111
VAL e 112
ARG e 114
MET e 115
ASP e 120
TYR a 452
ILE a 456
PCF e 202
6HU9_H_PCFH604 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B-C1
COMPLEX SUBUNIT 8;
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
PF00355
(COX4)
PF02921
(UCR_TM)
PF02936
(Rieske)
PF02935
(UcrQ)
PF02939
(COX7C)
8 GLY H  39
PHE H  41
HIS H  42
VAL H  45
GLY e  90
SER e  93
ALA e  96
LYS e  97
PCF H 604
6HU9_I_PCFI101 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL;
CYTOCHROME B-C1
COMPLEX SUBUNIT 9;
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
PF00115
(Peptidase_M16)
PF00675
(Peptidase_M16_C)
PF05193
(COX1)
PF00355
(COX4)
PF02921
(UCR_TM)
PF02936
(Rieske)
PF05365
(UCR_UQCRX_QCR9)
11 ASN I  14
VAL I  18
TYR E  57
VAL E  60
GLY E  64
SER E  68
ALA E  71
TRP A 427
ASP A 428
SER A 453
MET A 455
PCF I 101
6HU9_N_PCFN606 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B;
CYTOCHROME B-C1
COMPLEX SUBUNIT 7;
CYTOCHROME B-C1
COMPLEX SUBUNIT 8
None 16 TRP N  29
LEU R  41
GLN S  55
VAL S  59
GLU R  82
PHE N  94
MET N  95
MET N  97
ALA N  98
TYR N 102
TYR N 103
THR N 317
PHE N 327
VAL N 330
VAL N 334
TYR N 359
PCF N 606
6HU9_Q_PCFQ202 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL;
CYTOCHROME C OXIDASE
SUBUNIT 1
None 6 ALA q 111
ARG q 114
MET q 115
ASP q 120
TYR m 452
ILE m 456
PCF q 202
6HU9_S_PCFS603 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B-C1
COMPLEX SUBUNIT 8;
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
None 7 GLN S  38
GLY S  39
PHE S  41
HIS S  42
VAL S  45
SER q  93
LYS q  97
PCF S 603
6HU9_T_PCFT101 6hu9 PCF

DB09114
(Colfosceril
palmitate)
Saccharomyces
cerevisiae
CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL;
CYTOCHROME B-C1
COMPLEX SUBUNIT 9;
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
None 10 ASN T  14
VAL T  18
TYR P  57
VAL P  60
GLY P  64
SER P  68
ALA P  71
ASP L 428
SER L 453
MET L 455
PCF T 101