DRUG BINDING INTERFACES MAPPED TO 'DB08901'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3IK3_A_0LIA1	3ik3	0LI DB08901 (Ponatinib)	Mus musculus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	19	LEU A 248 TYR A 253 ALA A 269 LYS A 271 GLU A 286 VAL A 289 MET A 290 ILE A 293 LEU A 298 VAL A 299 ILE A 313 ILE A 315 MET A 318 HIS A 361 ARG A 362 LEU A 370 ALA A 380 ASP A 381 PHE A 382	0LI A 1
3IK3_B_0LIB2	3ik3	0LI DB08901 (Ponatinib)	Mus musculus	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1	no annotation	19	LEU B 248 TYR B 253 ALA B 269 LYS B 271 GLU B 286 VAL B 289 MET B 290 ILE B 293 LEU B 298 VAL B 299 ILE B 313 ILE B 315 MET B 318 HIS B 361 ARG B 362 LEU B 370 ALA B 380 ASP B 381 PHE B 382	0LI B 2
3OXZ_A_0LIA1	3oxz	0LI DB08901 (Ponatinib)	Mus musculus	TYROSINE-PROTEIN KINASE ABL1	PF07714 (Pkinase_Tyr)	21	LEU A 248 TYR A 253 ALA A 269 LYS A 271 GLU A 286 VAL A 289 MET A 290 ILE A 293 LEU A 298 VAL A 299 ILE A 313 THR A 315 MET A 318 GLY A 321 HIS A 361 ARG A 362 LEU A 370 VAL A 379 ALA A 380 ASP A 381 PHE A 382	0LI A 1
3ZOS_A_0LIA1000	3zos	0LI DB08901 (Ponatinib)	Homo sapiens	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1	PF07714 (Pkinase_Tyr)	21	LEU A 616 ALA A 653 LYS A 655 GLU A 672 ILE A 675 MET A 676 LEU A 679 ILE A 684 ILE A 685 MET A 699 THR A 701 TYR A 703 MET A 704 LEU A 757 HIS A 764 ARG A 765 LEU A 773 ILE A 782 ALA A 783 ASP A 784 PHE A 785	0LI A1000
3ZOS_A_0LIA1004	3zos	0LI DB08901 (Ponatinib)	Homo sapiens	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1	PF07714 (Pkinase_Tyr) no annotation	11	VAL A 799 VAL B 799 ALA A 803 LEU B 805 LEU A 805 LEU A 816 GLY A 818 GLY B 818 PHE B 820 ILE A 854 PHE A 861	0LI A1004
3ZOS_B_0LIB1000	3zos	0LI DB08901 (Ponatinib)	Homo sapiens	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1	no annotation	21	LEU B 616 ALA B 653 LYS B 655 GLU B 672 ILE B 675 MET B 676 LEU B 679 ILE B 684 ILE B 685 MET B 699 THR B 701 TYR B 703 MET B 704 LEU B 757 HIS B 764 ARG B 765 LEU B 773 ILE B 782 ALA B 783 ASP B 784 PHE B 785	0LI B1000
4C8B_A_0LIA1000	4c8b	0LI DB08901 (Ponatinib)	Homo sapiens	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2	PF07714 (Pkinase_Tyr)	17	VAL A 32 ALA A 45 LYS A 47 GLU A 66 LEU A 70 ILE A 78 LEU A 79 ILE A 93 THR A 95 TYR A 97 MET A 98 HIS A 144 LEU A 153 ILE A 162 ALA A 163 ASP A 164 PHE A 165	0LI A1000
4C8B_B_0LIB1000	4c8b	0LI DB08901 (Ponatinib)	Homo sapiens	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2	no annotation	15	ALA B 45 LYS B 47 GLU B 66 LEU B 70 ILE B 78 LEU B 79 THR B 95 TYR B 97 MET B 98 HIS B 144 LEU B 153 ILE B 162 ALA B 163 ASP B 164 PHE B 165	0LI B1000
4QRC_A_0LIA802	4qrc	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 4	PF07714 (Pkinase_Tyr)	20	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLU A 520 MET A 524 ILE A 534 VAL A 550 CYS A 552 ALA A 553 LEU A 603 CYS A 608 HIS A 610 ARG A 611 LEU A 619 ALA A 629 ASP A 630 PHE A 631 LEU A 633 ARG A 635	0LI A 802
4TYJ_A_0LIA801	4tyj	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 4	PF07714 (Pkinase_Tyr)	18	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLU A 520 MET A 524 ILE A 527 ILE A 533 VAL A 550 ALA A 553 CYS A 608 HIS A 610 ARG A 611 LEU A 619 ILE A 628 ALA A 629 ASP A 630 PHE A 631	0LI A 801
4U0I_A_0LIA1001	4u0i	0LI DB08901 (Ponatinib)	Homo sapiens	MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT	PF07714 (Pkinase_Tyr)	22	LEU A 595 VAL A 603 ALA A 621 LYS A 623 GLU A 640 LEU A 644 LEU A 647 ILE A 653 VAL A 654 VAL A 668 THR A 670 TYR A 672 CYS A 673 GLY A 676 CYS A 788 HIS A 790 ARG A 791 LEU A 799 ILE A 808 CYS A 809 ASP A 810 PHE A 811	0LI A1001
4UXQ_A_0LIA1752	4uxq	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 4	PF07714 (Pkinase_Tyr)	19	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLU A 520 MET A 524 ILE A 527 ILE A 534 VAL A 550 ALA A 553 LEU A 603 CYS A 608 HIS A 610 ARG A 611 LEU A 619 ILE A 628 ALA A 629 ASP A 630 PHE A 631	0LI A1752
4V01_A_0LIA1776	4v01	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B	PF07714 (Pkinase_Tyr)	21	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLU A 531 MET A 534 MET A 535 ILE A 538 ILE A 545 VAL A 561 TYR A 563 ALA A 564 LEU A 614 CYS A 619 HIS A 621 ARG A 622 LEU A 630 ILE A 639 ALA A 640 ASP A 641 PHE A 642	0LI A1776
4V01_B_0LIB1770	4v01	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B	no annotation	21	LEU B 484 VAL B 492 ALA B 512 LYS B 514 GLU B 531 MET B 534 MET B 535 ILE B 538 ILE B 545 VAL B 561 TYR B 563 ALA B 564 LEU B 614 CYS B 619 HIS B 621 ARG B 622 LEU B 630 ILE B 639 ALA B 640 ASP B 641 PHE B 642	0LI B1770
4V04_A_0LIA1772	4v04	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B	PF07714 (Pkinase_Tyr)	20	VAL A 492 ALA A 512 LYS A 514 GLU A 531 MET A 534 MET A 535 ILE A 545 VAL A 561 TYR A 563 ALA A 564 LEU A 614 CYS A 619 HIS A 621 ARG A 622 LEU A 630 ILE A 639 ALA A 640 ASP A 641 PHE A 642 GLY A 643	0LI A1772
4V04_B_0LIB1771	4v04	0LI DB08901 (Ponatinib)	Homo sapiens	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B	no annotation	22	LEU B 484 VAL B 492 ALA B 512 LYS B 514 GLU B 531 MET B 534 MET B 535 ILE B 545 VAL B 561 TYR B 563 ALA B 564 LEU B 614 CYS B 619 HIS B 621 ARG B 622 LEU B 630 ILE B 639 ALA B 640 ASP B 641 PHE B 642 GLY B 643 LEU B 644	0LI B1771

[["3IK3_A_0LIA1","3ik3","0LI","DB08901(Ponatinib)","Mus musculus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",19,"LEU A 248;TYR A 253;ALA A 269;LYS A 271;GLU A 286;VAL A 289;MET A 290;ILE A 293;LEU A 298;VAL A 299;ILE A 313;ILE A 315;MET A 318;HIS A 361;ARG A 362;LEU A 370;ALA A 380;ASP A 381;PHE A 382","0LI A   1\r"],["3IK3_B_0LIB2","3ik3","0LI","DB08901(Ponatinib)","Mus musculus","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","no annotation",19,"LEU B 248;TYR B 253;ALA B 269;LYS B 271;GLU B 286;VAL B 289;MET B 290;ILE B 293;LEU B 298;VAL B 299;ILE B 313;ILE B 315;MET B 318;HIS B 361;ARG B 362;LEU B 370;ALA B 380;ASP B 381;PHE B 382","0LI B   2\r"],["3OXZ_A_0LIA1","3oxz","0LI","DB08901(Ponatinib)","Mus musculus","TYROSINE-PROTEIN KINASE ABL1","PF07714(Pkinase_Tyr)",21,"LEU A 248;TYR A 253;ALA A 269;LYS A 271;GLU A 286;VAL A 289;MET A 290;ILE A 293;LEU A 298;VAL A 299;ILE A 313;THR A 315;MET A 318;GLY A 321;HIS A 361;ARG A 362;LEU A 370;VAL A 379;ALA A 380;ASP A 381;PHE A 382","0LI A   1\r"],["3ZOS_A_0LIA1000","3zos","0LI","DB08901(Ponatinib)","Homo sapiens","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","PF07714(Pkinase_Tyr)",21,"LEU A 616;ALA A 653;LYS A 655;GLU A 672;ILE A 675;MET A 676;LEU A 679;ILE A 684;ILE A 685;MET A 699;THR A 701;TYR A 703;MET A 704;LEU A 757;HIS A 764;ARG A 765;LEU A 773;ILE A 782;ALA A 783;ASP A 784;PHE A 785","0LI A1000\r"],["3ZOS_A_0LIA1004","3zos","0LI","DB08901(Ponatinib)","Homo sapiens","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","PF07714(Pkinase_Tyr);no annotation",11,"VAL A 799;VAL B 799;ALA A 803;LEU B 805;LEU A 805;LEU A 816;GLY A 818;GLY B 818;PHE B 820;ILE A 854;PHE A 861","0LI A1004\r"],["3ZOS_B_0LIB1000","3zos","0LI","DB08901(Ponatinib)","Homo sapiens","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","no annotation",21,"LEU B 616;ALA B 653;LYS B 655;GLU B 672;ILE B 675;MET B 676;LEU B 679;ILE B 684;ILE B 685;MET B 699;THR B 701;TYR B 703;MET B 704;LEU B 757;HIS B 764;ARG B 765;LEU B 773;ILE B 782;ALA B 783;ASP B 784;PHE B 785","0LI B1000\r"],["4C8B_A_0LIA1000","4c8b","0LI","DB08901(Ponatinib)","Homo sapiens","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","PF07714(Pkinase_Tyr)",17,"VAL A  32;ALA A  45;LYS A  47;GLU A  66;LEU A  70;ILE A  78;LEU A  79;ILE A  93;THR A  95;TYR A  97;MET A  98;HIS A 144;LEU A 153;ILE A 162;ALA A 163;ASP A 164;PHE A 165","0LI A1000\r"],["4C8B_B_0LIB1000","4c8b","0LI","DB08901(Ponatinib)","Homo sapiens","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","no annotation",15,"ALA B  45;LYS B  47;GLU B  66;LEU B  70;ILE B  78;LEU B  79;THR B  95;TYR B  97;MET B  98;HIS B 144;LEU B 153;ILE B 162;ALA B 163;ASP B 164;PHE B 165","0LI B1000\r"],["4QRC_A_0LIA802","4qrc","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 4","PF07714(Pkinase_Tyr)",20,"LEU A 473;VAL A 481;ALA A 501;LYS A 503;GLU A 520;MET A 524;ILE A 534;VAL A 550;CYS A 552;ALA A 553;LEU A 603;CYS A 608;HIS A 610;ARG A 611;LEU A 619;ALA A 629;ASP A 630;PHE A 631;LEU A 633;ARG A 635","0LI A 802\r"],["4TYJ_A_0LIA801","4tyj","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 4","PF07714(Pkinase_Tyr)",18,"LEU A 473;VAL A 481;ALA A 501;LYS A 503;GLU A 520;MET A 524;ILE A 527;ILE A 533;VAL A 550;ALA A 553;CYS A 608;HIS A 610;ARG A 611;LEU A 619;ILE A 628;ALA A 629;ASP A 630;PHE A 631","0LI A 801\r"],["4U0I_A_0LIA1001","4u0i","0LI","DB08901(Ponatinib)","Homo sapiens","MAST\/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST\/STEM CELL GROWTH FACTOR RECEPTOR KIT","PF07714(Pkinase_Tyr)",22,"LEU A 595;VAL A 603;ALA A 621;LYS A 623;GLU A 640;LEU A 644;LEU A 647;ILE A 653;VAL A 654;VAL A 668;THR A 670;TYR A 672;CYS A 673;GLY A 676;CYS A 788;HIS A 790;ARG A 791;LEU A 799;ILE A 808;CYS A 809;ASP A 810;PHE A 811","0LI A1001\r"],["4UXQ_A_0LIA1752","4uxq","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 4","PF07714(Pkinase_Tyr)",19,"LEU A 473;VAL A 481;ALA A 501;LYS A 503;GLU A 520;MET A 524;ILE A 527;ILE A 534;VAL A 550;ALA A 553;LEU A 603;CYS A 608;HIS A 610;ARG A 611;LEU A 619;ILE A 628;ALA A 629;ASP A 630;PHE A 631","0LI A1752\r"],["4V01_A_0LIA1776","4v01","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","PF07714(Pkinase_Tyr)",21,"LEU A 484;VAL A 492;ALA A 512;LYS A 514;GLU A 531;MET A 534;MET A 535;ILE A 538;ILE A 545;VAL A 561;TYR A 563;ALA A 564;LEU A 614;CYS A 619;HIS A 621;ARG A 622;LEU A 630;ILE A 639;ALA A 640;ASP A 641;PHE A 642","0LI A1776\r"],["4V01_B_0LIB1770","4v01","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","no annotation",21,"LEU B 484;VAL B 492;ALA B 512;LYS B 514;GLU B 531;MET B 534;MET B 535;ILE B 538;ILE B 545;VAL B 561;TYR B 563;ALA B 564;LEU B 614;CYS B 619;HIS B 621;ARG B 622;LEU B 630;ILE B 639;ALA B 640;ASP B 641;PHE B 642","0LI B1770\r"],["4V04_A_0LIA1772","4v04","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","PF07714(Pkinase_Tyr)",20,"VAL A 492;ALA A 512;LYS A 514;GLU A 531;MET A 534;MET A 535;ILE A 545;VAL A 561;TYR A 563;ALA A 564;LEU A 614;CYS A 619;HIS A 621;ARG A 622;LEU A 630;ILE A 639;ALA A 640;ASP A 641;PHE A 642;GLY A 643","0LI A1772\r"],["4V04_B_0LIB1771","4v04","0LI","DB08901(Ponatinib)","Homo sapiens","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","no annotation",22,"LEU B 484;VAL B 492;ALA B 512;LYS B 514;GLU B 531;MET B 534;MET B 535;ILE B 545;VAL B 561;TYR B 563;ALA B 564;LEU B 614;CYS B 619;HIS B 621;ARG B 622;LEU B 630;ILE B 639;ALA B 640;ASP B 641;PHE B 642;GLY B 643;LEU B 644","0LI B1771\r"]]