DRUG BINDING INTERFACES MAPPED TO 'DB08895'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3EYG_A_MI1A1	3eyg	MI1 DB08895 (Tofacitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE	PF07714 (Pkinase_Tyr)	12	LEU A 881 GLY A 882 GLY A 884 GLY A 887 VAL A 889 ALA A 906 LYS A 908 MET A 956 SER A 963 ASN A1008 LEU A1010 ASP A1021	MI1 A 1
3FUP_A_MI1A1	3fup	MI1 DB08895 (Tofacitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE JAK2	PF07714 (Pkinase_Tyr)	13	LEU A 855 GLY A 856 GLY A 858 GLY A 861 VAL A 863 ALA A 880 LYS A 882 MET A 929 TYR A 931 SER A 936 ASN A 981 LEU A 983 ASP A 994	MI1 A 1
3FUP_B_MI1B1	3fup	MI1 DB08895 (Tofacitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE JAK2	no annotation	13	LEU B 855 GLY B 856 GLY B 858 VAL B 863 ALA B 880 LYS B 882 VAL B 911 MET B 929 TYR B 931 LEU B 932 ASN B 981 LEU B 983 ASP B 994	MI1 B 1
3LXK_A_MI1A1125	3lxk	MI1 DB08895 (Tofacitinib)	Homo sapiens	TYROSINE-PROTEIN KINASE JAK3	PF07714 (Pkinase_Tyr)	13	LEU A 828 GLY A 829 VAL A 836 ALA A 853 LYS A 855 VAL A 884 MET A 902 TYR A 904 CYS A 909 ASN A 954 LEU A 956 ALA A 966 ASP A 967	MI1 A1125
3LXN_A_MI1A1	3lxn	MI1 DB08895 (Tofacitinib)	Homo sapiens	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2	PF07714 (Pkinase_Tyr)	13	LEU A 903 GLY A 904 GLY A 906 VAL A 911 ALA A 928 LYS A 930 ILE A 960 TYR A 980 VAL A 981 SER A 985 ASN A1028 LEU A1030 ASP A1041	MI1 A 1
4OTI_A_MI1A1001	4oti	MI1 DB08895 (Tofacitinib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE N1	PF00069 (Pkinase) PF00433 (Pkinase_C)	14	LEU A 627 GLY A 628 GLY A 630 GLY A 633 VAL A 635 ALA A 648 LYS A 650 VAL A 685 TYR A 703 ASN A 751 LEU A 753 ALA A 763 ASP A 764 PHE A 910	MI1 A1001

[["3EYG_A_MI1A1","3eyg","MI1","DB08895(Tofacitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE","PF07714(Pkinase_Tyr)",12,"LEU A 881;GLY A 882;GLY A 884;GLY A 887;VAL A 889;ALA A 906;LYS A 908;MET A 956;SER A 963;ASN A1008;LEU A1010;ASP A1021","MI1 A   1\r"],["3FUP_A_MI1A1","3fup","MI1","DB08895(Tofacitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE JAK2","PF07714(Pkinase_Tyr)",13,"LEU A 855;GLY A 856;GLY A 858;GLY A 861;VAL A 863;ALA A 880;LYS A 882;MET A 929;TYR A 931;SER A 936;ASN A 981;LEU A 983;ASP A 994","MI1 A   1\r"],["3FUP_B_MI1B1","3fup","MI1","DB08895(Tofacitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE JAK2","no annotation",13,"LEU B 855;GLY B 856;GLY B 858;VAL B 863;ALA B 880;LYS B 882;VAL B 911;MET B 929;TYR B 931;LEU B 932;ASN B 981;LEU B 983;ASP B 994","MI1 B   1\r"],["3LXK_A_MI1A1125","3lxk","MI1","DB08895(Tofacitinib)","Homo sapiens","TYROSINE-PROTEIN KINASE JAK3","PF07714(Pkinase_Tyr)",13,"LEU A 828;GLY A 829;VAL A 836;ALA A 853;LYS A 855;VAL A 884;MET A 902;TYR A 904;CYS A 909;ASN A 954;LEU A 956;ALA A 966;ASP A 967","MI1 A1125\r"],["3LXN_A_MI1A1","3lxn","MI1","DB08895(Tofacitinib)","Homo sapiens","NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2","PF07714(Pkinase_Tyr)",13,"LEU A 903;GLY A 904;GLY A 906;VAL A 911;ALA A 928;LYS A 930;ILE A 960;TYR A 980;VAL A 981;SER A 985;ASN A1028;LEU A1030;ASP A1041","MI1 A   1\r"],["4OTI_A_MI1A1001","4oti","MI1","DB08895(Tofacitinib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE N1","PF00069(Pkinase);PF00433(Pkinase_C)",14,"LEU A 627;GLY A 628;GLY A 630;GLY A 633;VAL A 635;ALA A 648;LYS A 650;VAL A 685;TYR A 703;ASN A 751;LEU A 753;ALA A 763;ASP A 764;PHE A 910","MI1 A1001\r"]]