DRUG BINDING INTERFACES MAPPED TO 'DB01259'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1XKK_A_FMMA91 1xkk FMM

DB01259
(Lapatinib)
Homo sapiens EPIDERMAL GROWTH
FACTOR RECEPTOR
PF07714
(Pkinase_Tyr)
21 LEU A 718
VAL A 726
ALA A 743
LYS A 745
MET A 766
CYS A 775
LEU A 777
LEU A 788
THR A 790
LEU A 792
MET A 793
GLY A 796
CYS A 797
LEU A 799
ASP A 800
ARG A 803
LEU A 844
THR A 854
ASP A 855
PHE A 856
LEU A 858
FMM A  91
3BBT_B_FMMB91 3bbt FMM

DB01259
(Lapatinib)
Homo sapiens RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
PF07714
(Pkinase_Tyr)
14 VAL B 707
ALA B 724
LYS B 726
MET B 747
LEU B 758
LEU B 769
THR B 771
LEU B 773
GLY B 777
LEU B 825
THR B 835
ASP B 836
PHE B 837
LEU B 839
FMM B  91
3BBT_D_FMMD91 3bbt FMM

DB01259
(Lapatinib)
Homo sapiens RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4
no annotation 13 VAL D 707
ALA D 724
LYS D 726
MET D 747
LEU D 769
THR D 771
MET D 774
GLY D 777
LEU D 825
THR D 835
ASP D 836
PHE D 837
LEU D 839
FMM D  91