DRUG BINDING INTERFACES MAPPED TO 'DB01137'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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All hits from Homo Sapiens
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
3K9F_F_LFXF0
3k9f
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
5
SER A 79ARG B 117ARG C 456GLY C 457GLU C 475
LFX F 0
3K9F_H_LFXH0
3k9f
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)no annotation
6
SER B 79ARG A 117ARG D 456GLY D 457GLU D 474GLU D 475
LFX H 0
3RAE_F_LFXF101
3rae
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
4
SER A 79ARG C 456GLY C 457GLU C 474
LFX F 101
3RAE_H_LFXH101
3rae
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
no annotation
5
SER B 79ARG D 456GLY D 457GLU D 474GLU D 475
LFX H 101
4JUO_F_LFXF101
4juo
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B;E-SITE DNA
PF00204(DNA_gyraseB)PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)PF02518(HATPase_c)no annotation
4
SER A 79ARG C 456GLY C 457GLU C 474
LFX F 101
4Z2D_F_LFXF102
4z2d
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
Escherichia coli;Streptococcuspneumoniae
DNA GYRASE SUBUNITA;DNA GYRASE SUBUNITB;SYMMETRIZED E-SITEDNA
PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
4
SER B 81ARG C 456GLY C 457GLU C 475
LFX F 102
4Z2D_H_LFXH101
4z2d
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
Escherichia coli;Streptococcuspneumoniae
DNA GYRASE SUBUNITA;DNA GYRASE SUBUNITB;SYMMETRIZED E-SITEDNA
PF00521(DNA_topoisoIV)no annotation
4
SER A 81ARG D 456GLY D 457GLU D 475
LFX H 101
5BTG_E_LFXE101
5btg
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
Mycobacteriumtuberculosis;syntheticconstruct
DNA GYRASE SUBUNITA;DNA GYRASE SUBUNITB;DNA SUBSTRATE 24-MERGGTCATGAATGACTATGCACGTAA
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
6
ALA A 90ARG C 128ARG B 482GLY B 483THR B 500GLU B 501
LFX E 101
5BTG_F_LFXF101
5btg
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
Mycobacteriumtuberculosis;syntheticconstruct
DNA GYRASE SUBUNITA;DNA GYRASE SUBUNITB;DNA SUBSTRATE 24-MERTTACGTGCATAGTCATTCATGACC
PF00521(DNA_topoisoIV)no annotation
7
ALA C 90ARG A 128ASP D 461ARG D 482GLY D 483THR D 500GLU D 501
LFX F 101
5BTI_E_LFXE101
5bti
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
Mycobacteriumtuberculosis;syntheticconstruct
DNA GYRASE SUBUNITA;DNA GYRASE SUBUNITB;DNA SUBSTRATE 24-MERGGTCATGAATGACTATGCACGTAA
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
5
SER A 90ARG B 482GLY B 483THR B 500GLU B 501
LFX E 101
5BTI_F_LFXF101
5bti
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
Mycobacteriumtuberculosis;syntheticconstruct
DNA GYRASE SUBUNITA;DNA GYRASE SUBUNITB;DNA SUBSTRATE 24-MERTTACGTGCATAGTCATTCATGACC
no annotation
5
SER C 90ARG D 482GLY D 483THR D 500GLU D 501
LFX F 101
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