DRUG BINDING INTERFACES MAPPED TO 'DB00684'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1M4D_A_TOYA500 1m4d TOY

DB00684
(Tobramycin)
Mycobacterium
tuberculosis
AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
PF13527
(Acetyltransf_9)
10 PHE A  32
ASP A  35
ASP A  40
GLU A  82
SER A 117
SER A 119
ALA A 120
ASP A 152
THR A 155
ASP A 179
TOY A 500
1M4D_B_TOYB501 1m4d TOY

DB00684
(Tobramycin)
Mycobacterium
tuberculosis
AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE
no annotation 9 ASP B  35
ASP B  40
GLU B  82
SER B 117
SER B 119
ALA B 120
ASP B 152
THR B 155
ASP B 179
TOY B 501
3SG8_A_TOYA305 3sg8 TOY

DB00684
(Tobramycin)
Enterococcus
casseliflavus
APH(2'')-ID PF01636
(APH)
13 ASN A  32
ASP A 197
SER A 199
ASP A 201
HIS A 202
ASP A 220
GLU A 235
GLU A 238
GLU A 239
TRP A 271
GLU A 274
TYR A 278
TRP A 287
TOY A 305
3SG8_B_TOYB305 3sg8 TOY

DB00684
(Tobramycin)
Enterococcus
casseliflavus
APH(2'')-ID no annotation 12 ASN B  32
ASP B 197
SER B 199
ASP B 201
HIS B 202
ASP B 220
GLU B 235
GLU B 238
GLU B 239
TRP B 271
TYR B 278
TRP B 287
TOY B 305
3VET_A_TOYA604 3vet TOY

DB00684
(Tobramycin)
Streptoalloteichu
s tenebrarius
O-CARBAMOYLTRANSFERA
SE TOBZ
PF02543
(Carbam_trans_N)
PF16861
(Carbam_trans_C)
9 ASP A  12
HIS A  14
TYR A  42
PHE A 169
GLU A 172
GLU A 176
ASP A 183
ASP A 228
TYR A 230
TOY A 604
4EBK_A_TOYA301 4ebk TOY

DB00684
(Tobramycin)
Pseudomonas
aeruginosa
AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE
PF01909
(NTP_transf_2)
no annotation
9 ASP B  40
GLU B  51
TYR B  53
ALA B  70
GLU A 122
GLU A 124
GLU A 126
ASP A 127
GLU A 130
TOY A 301
4EBK_B_TOYB302 4ebk TOY

DB00684
(Tobramycin)
Pseudomonas
aeruginosa
AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE
PF01909
(NTP_transf_2)
no annotation
9 ASP A  40
GLU A  51
TYR A  53
ALA A  70
GLU B 122
GLU B 124
GLU B 126
ASP B 127
GLU B 130
TOY B 302
4EVY_A_TOYA201 4evy TOY

DB00684
(Tobramycin)
Acinetobacter
haemolyticus
AMINOGLYCOSIDE
N(6')-ACETYLTRANSFER
ASE TYPE 1
PF00583
(Acetyltransf_1)
no annotation
9 ARG A  18
TRP A  22
GLU A  32
TYR B  65
ASN B  67
GLU A  78
GLY A  79
ASP A 114
GLU B 135
TOY A 201
4EVY_B_TOYB201 4evy TOY

DB00684
(Tobramycin)
Acinetobacter
haemolyticus
AMINOGLYCOSIDE
N(6')-ACETYLTRANSFER
ASE TYPE 1
PF00583
(Acetyltransf_1)
no annotation
10 ARG B  18
TRP B  22
ASP B  24
GLU B  32
TYR A  65
ASN A  67
GLU B  78
GLY B  79
ASP B 114
GLU A 135
TOY B 201
4JD6_A_TOYA501 4jd6 TOY

DB00684
(Tobramycin)
Mycobacterium
tuberculosis
ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN
PF13527
(Acetyltransf_9)
PF13530
(SCP2_2)
9 PHE A  24
ASP A  26
ILE A  28
TRP A  36
SER A  83
VAL A  85
TYR A 126
GLU A 203
GLU A 401
TOY A 501
4JD6_B_TOYB501 4jd6 TOY

DB00684
(Tobramycin)
Mycobacterium
tuberculosis
ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN
no annotation 9 PHE B  24
ASP B  26
ILE B  28
TRP B  36
SER B  83
VAL B  85
TYR B 126
GLU B 203
GLU B 401
TOY B 501
4XJE_A_TOYA202 4xje TOY

DB00684
(Tobramycin)
Pseudomonas
aeruginosa
AADB PF10706
(Aminoglyc_resit)
8 ASP A  44
ASP A  46
TYR A  74
ASP A  86
GLU A  88
ILE A  99
ASP A 131
TYR A 134
TOY A 202
5CFS_A_TOYA203 5cfs TOY

DB00684
(Tobramycin)
Pseudomonas
aeruginosa
AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN
PF10706
(Aminoglyc_resit)
8 ASP A  44
ASP A  46
TYR A  74
ASP A  86
GLU A  88
ILE A  99
ASP A 131
TYR A 134
TOY A 203