DRUG BINDING INTERFACES MAPPED TO 'DB00684'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1M4D_A_TOYA500
1m4d
TOY
DB00684(Tobramycin)
Mycobacteriumtuberculosis
AMINOGLYCOSIDE2'-N-ACETYLTRANSFERASE
PF13527(Acetyltransf_9)
10
PHE A 32ASP A 35ASP A 40GLU A 82SER A 117SER A 119ALA A 120ASP A 152THR A 155ASP A 179
TOY A 500
1M4D_B_TOYB501
1m4d
TOY
DB00684(Tobramycin)
Mycobacteriumtuberculosis
AMINOGLYCOSIDE2'-N-ACETYLTRANSFERASE
no annotation
9
ASP B 35ASP B 40GLU B 82SER B 117SER B 119ALA B 120ASP B 152THR B 155ASP B 179
TOY B 501
3SG8_A_TOYA305
3sg8
TOY
DB00684(Tobramycin)
Enterococcuscasseliflavus
APH(2'')-ID
PF01636(APH)
13
ASN A 32ASP A 197SER A 199ASP A 201HIS A 202ASP A 220GLU A 235GLU A 238GLU A 239TRP A 271GLU A 274TYR A 278TRP A 287
TOY A 305
3SG8_B_TOYB305
3sg8
TOY
DB00684(Tobramycin)
Enterococcuscasseliflavus
APH(2'')-ID
no annotation
12
ASN B 32ASP B 197SER B 199ASP B 201HIS B 202ASP B 220GLU B 235GLU B 238GLU B 239TRP B 271TYR B 278TRP B 287
TOY B 305
3VET_A_TOYA604
3vet
TOY
DB00684(Tobramycin)
Streptoalloteichus tenebrarius
O-CARBAMOYLTRANSFERASE TOBZ
PF02543(Carbam_trans_N)PF16861(Carbam_trans_C)
9
ASP A 12HIS A 14TYR A 42PHE A 169GLU A 172GLU A 176ASP A 183ASP A 228TYR A 230
TOY A 604
4EBK_A_TOYA301
4ebk
TOY
DB00684(Tobramycin)
Pseudomonasaeruginosa
AMINOGLYCOSIDENUCLEOTIDYLTRANSFERASE
PF01909(NTP_transf_2)no annotation
9
ASP B 40GLU B 51TYR B 53ALA B 70GLU A 122GLU A 124GLU A 126ASP A 127GLU A 130
TOY A 301
4EBK_B_TOYB302
4ebk
TOY
DB00684(Tobramycin)
Pseudomonasaeruginosa
AMINOGLYCOSIDENUCLEOTIDYLTRANSFERASE
PF01909(NTP_transf_2)no annotation
9
ASP A 40GLU A 51TYR A 53ALA A 70GLU B 122GLU B 124GLU B 126ASP B 127GLU B 130
TOY B 302
4EVY_A_TOYA201
4evy
TOY
DB00684(Tobramycin)
Acinetobacterhaemolyticus
AMINOGLYCOSIDEN(6')-ACETYLTRANSFERASE TYPE 1
PF00583(Acetyltransf_1)no annotation
9
ARG A 18TRP A 22GLU A 32TYR B 65ASN B 67GLU A 78GLY A 79ASP A 114GLU B 135
TOY A 201
4EVY_B_TOYB201
4evy
TOY
DB00684(Tobramycin)
Acinetobacterhaemolyticus
AMINOGLYCOSIDEN(6')-ACETYLTRANSFERASE TYPE 1
PF00583(Acetyltransf_1)no annotation
10
ARG B 18TRP B 22ASP B 24GLU B 32TYR A 65ASN A 67GLU B 78GLY B 79ASP B 114GLU A 135
TOY B 201
4JD6_A_TOYA501
4jd6
TOY
DB00684(Tobramycin)
Mycobacteriumtuberculosis
ENHANCEDINTRACELLULARSURVIVAL PROTEIN
PF13527(Acetyltransf_9)PF13530(SCP2_2)
9
PHE A 24ASP A 26ILE A 28TRP A 36SER A 83VAL A 85TYR A 126GLU A 203GLU A 401
TOY A 501
4JD6_B_TOYB501
4jd6
TOY
DB00684(Tobramycin)
Mycobacteriumtuberculosis
ENHANCEDINTRACELLULARSURVIVAL PROTEIN
no annotation
9
PHE B 24ASP B 26ILE B 28TRP B 36SER B 83VAL B 85TYR B 126GLU B 203GLU B 401
TOY B 501
4XJE_A_TOYA202
4xje
TOY
DB00684(Tobramycin)
Pseudomonasaeruginosa
AADB
PF10706(Aminoglyc_resit)
8
ASP A 44ASP A 46TYR A 74ASP A 86GLU A 88ILE A 99ASP A 131TYR A 134
TOY A 202
5CFS_A_TOYA203
5cfs
TOY
DB00684(Tobramycin)
Pseudomonasaeruginosa
AAD(2''),GENTAMICIN2''-NUCLEOTIDYLTRANSFERASE,GENTAMICINRESISTANCE PROTEIN
PF10706(Aminoglyc_resit)
8
ASP A 44ASP A 46TYR A 74ASP A 86GLU A 88ILE A 99ASP A 131TYR A 134
TOY A 203
[["1M4D_A_TOYA500","1m4d","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","PF13527(Acetyltransf_9)",10,"PHE A 32;ASP A 35;ASP A 40;GLU A 82;SER A 117;SER A 119;ALA A 120;ASP A 152;THR A 155;ASP A 179","TOY A 500\r"],["1M4D_B_TOYB501","1m4d","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","no annotation",9,"ASP B 35;ASP B 40;GLU B 82;SER B 117;SER B 119;ALA B 120;ASP B 152;THR B 155;ASP B 179","TOY B 501\r"],["3SG8_A_TOYA305","3sg8","TOY","DB00684(Tobramycin)","Enterococcus casseliflavus","APH(2'')-ID","PF01636(APH)",13,"ASN A 32;ASP A 197;SER A 199;ASP A 201;HIS A 202;ASP A 220;GLU A 235;GLU A 238;GLU A 239;TRP A 271;GLU A 274;TYR A 278;TRP A 287","TOY A 305\r"],["3SG8_B_TOYB305","3sg8","TOY","DB00684(Tobramycin)","Enterococcus casseliflavus","APH(2'')-ID","no annotation",12,"ASN B 32;ASP B 197;SER B 199;ASP B 201;HIS B 202;ASP B 220;GLU B 235;GLU B 238;GLU B 239;TRP B 271;TYR B 278;TRP B 287","TOY B 305\r"],["3VET_A_TOYA604","3vet","TOY","DB00684(Tobramycin)","Streptoalloteichus tenebrarius","O-CARBAMOYLTRANSFERASE TOBZ","PF02543(Carbam_trans_N);PF16861(Carbam_trans_C)",9,"ASP A 12;HIS A 14;TYR A 42;PHE A 169;GLU A 172;GLU A 176;ASP A 183;ASP A 228;TYR A 230","TOY A 604\r"],["4EBK_A_TOYA301","4ebk","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE","PF01909(NTP_transf_2);no annotation",9,"ASP B 40;GLU B 51;TYR B 53;ALA B 70;GLU A 122;GLU A 124;GLU A 126;ASP A 127;GLU A 130","TOY A 301\r"],["4EBK_B_TOYB302","4ebk","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE","PF01909(NTP_transf_2);no annotation",9,"ASP A 40;GLU A 51;TYR A 53;ALA A 70;GLU B 122;GLU B 124;GLU B 126;ASP B 127;GLU B 130","TOY B 302\r"],["4EVY_A_TOYA201","4evy","TOY","DB00684(Tobramycin)","Acinetobacter haemolyticus","AMINOGLYCOSIDE N(6')-ACETYLTRANSFERASE TYPE 1","PF00583(Acetyltransf_1);no annotation",9,"ARG A 18;TRP A 22;GLU A 32;TYR B 65;ASN B 67;GLU A 78;GLY A 79;ASP A 114;GLU B 135","TOY A 201\r"],["4EVY_B_TOYB201","4evy","TOY","DB00684(Tobramycin)","Acinetobacter haemolyticus","AMINOGLYCOSIDE N(6')-ACETYLTRANSFERASE TYPE 1","PF00583(Acetyltransf_1);no annotation",10,"ARG B 18;TRP B 22;ASP B 24;GLU B 32;TYR A 65;ASN A 67;GLU B 78;GLY B 79;ASP B 114;GLU A 135","TOY B 201\r"],["4JD6_A_TOYA501","4jd6","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","PF13527(Acetyltransf_9);PF13530(SCP2_2)",9,"PHE A 24;ASP A 26;ILE A 28;TRP A 36;SER A 83;VAL A 85;TYR A 126;GLU A 203;GLU A 401","TOY A 501\r"],["4JD6_B_TOYB501","4jd6","TOY","DB00684(Tobramycin)","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","no annotation",9,"PHE B 24;ASP B 26;ILE B 28;TRP B 36;SER B 83;VAL B 85;TYR B 126;GLU B 203;GLU B 401","TOY B 501\r"],["4XJE_A_TOYA202","4xje","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AADB","PF10706(Aminoglyc_resit)",8,"ASP A 44;ASP A 46;TYR A 74;ASP A 86;GLU A 88;ILE A 99;ASP A 131;TYR A 134","TOY A 202\r"],["5CFS_A_TOYA203","5cfs","TOY","DB00684(Tobramycin)","Pseudomonas aeruginosa","AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN","PF10706(Aminoglyc_resit)",8,"ASP A 44;ASP A 46;TYR A 74;ASP A 86;GLU A 88;ILE A 99;ASP A 131;TYR A 134","TOY A 203\r"]]