DRUG BINDING INTERFACES MAPPED TO 'DB00625'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1FK9_A_EFZA999
1fk9
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
HIV-1 RT, A-CHAIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
LEU A 100LYS A 101LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190LEU A 234TYR A 318
EFZ A 999
1FKO_A_EFZA999
1fko
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
HIV-1 RT, A-CHAIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
LEU A 100ASN A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A 999
1IKV_A_EFZA2000
1ikv
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
POL POLYPROTEIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
9
LEU A 100VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A2000
1IKW_A_EFZA2000
1ikw
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
POL POLYPROTEIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A2000
1JKH_A_EFZA999
1jkh
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
HIV-1 RT, A-CHAIN;HIV-1 RT, B-CHAIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
11
LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179CYS A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A 999
4B3O_A_EFZA1557
4b3o
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
9
LEU A 100LYS A 101LYS A 103VAL A 106TYR A 181TYR A 188GLY A 190LEU A 234TYR A 318
EFZ A1557
6BSG_A_EFZA601
6bsg
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE P66SUBUNIT
no annotation
10
LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A 601
6BSH_A_EFZA601
6bsh
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE P51SUBUNIT;REVERSETRANSCRIPTASE P66SUBUNIT
no annotation
11
LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A 601
6BSI_A_EFZA601
6bsi
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE P66SUBUNIT
no annotation
10
LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A 601
6BSJ_A_EFZA601
6bsj
EFZ
DB00625(Efavirenz)
Humanimmunodeficiencyvirus 1
REVERSETRANSCRIPTASE P66SUBUNIT
no annotation
10
LEU A 100LYS A 103VAL A 106VAL A 179TYR A 181TYR A 188GLY A 190TRP A 229LEU A 234TYR A 318
EFZ A 601
[["1FK9_A_EFZA999","1fk9","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","HIV-1 RT, A-CHAIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;LYS A 101;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;LEU A 234;TYR A 318","EFZ A 999\r"],["1FKO_A_EFZA999","1fko","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","HIV-1 RT, A-CHAIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;ASN A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 999\r"],["1IKV_A_EFZA2000","1ikv","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","POL POLYPROTEIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",9,"LEU A 100;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A2000\r"],["1IKW_A_EFZA2000","1ikw","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","POL POLYPROTEIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A2000\r"],["1JKH_A_EFZA999","1jkh","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","HIV-1 RT, A-CHAIN;HIV-1 RT, B-CHAIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",11,"LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;CYS A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 999\r"],["4B3O_A_EFZA1557","4b3o","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",9,"LEU A 100;LYS A 101;LYS A 103;VAL A 106;TYR A 181;TYR A 188;GLY A 190;LEU A 234;TYR A 318","EFZ A1557\r"],["6BSG_A_EFZA601","6bsg","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"],["6BSH_A_EFZA601","6bsh","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P51 SUBUNIT;REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",11,"LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"],["6BSI_A_EFZA601","6bsi","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"],["6BSJ_A_EFZA601","6bsj","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"]]