DRUG BINDING INTERFACES MAPPED TO 'DB00537'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1T9U_A_CPFA5002 1t9u CPF

DB00537
(Ciprofloxacin)
Escherichia coli ACRIFLAVINE
RESISTANCE PROTEIN B
PF00873
(ACR_tran)
6 PHE A 664
PHE A 666
ASN A 667
ARG A 717
ASN A 719
GLN A 830
CPF A5002
2XCT_G_CPFG1020 2xct CPF

DB00537
(Ciprofloxacin)
Staphylococcus
aureus;
synthetic
construct
DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A
PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
no annotation
3 ARG B 458
GLY B 459
SER B1084
CPF G1020
2XCT_H_CPFH1020 2xct CPF

DB00537
(Ciprofloxacin)
Staphylococcus
aureus;
synthetic
construct
DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A
no annotation 3 ARG D 458
GLU D 477
SER D1084
CPF H1020
2XCT_X_CPFX1020 2xct CPF

DB00537
(Ciprofloxacin)
Staphylococcus
aureus;
synthetic
construct
DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A
no annotation 4 ARG S 458
GLY S 459
GLU S 477
SER U1084
CPF X1020
4BVV_A_CPFA1081 4bvv CPF

DB00537
(Ciprofloxacin)
Homo sapiens APOLIPOPROTEIN(A) PF00051
(Kringle)
9 HIS A  33
SER A  34
THR A  35
ASP A  55
ASP A  57
TRP A  62
TYR A  64
LEU A  71
PHE A  72
CPF A1081
4KRA_C_CPFC401 4kra CPF

DB00537
(Ciprofloxacin)
Salmonella
enterica
OUTER MEMBRANE
PROTEIN F
no annotation 9 ARG C  20
TYR C  36
ARG C  60
ARG C  77
TYR C 112
GLU C 116
GLY C 120
THR C 123
ARG C 130
CPF C 401
5BTC_G_CPFG101 5btc CPF

DB00537
(Ciprofloxacin)
Mycobacterium
tuberculosis;
synthetic
construct
DNA GYRASE SUBUNIT
A;
DNA GYRASE SUBUNIT
B;
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC
PF00521
(DNA_topoisoIV)
no annotation
6 SER C  90
ARG A 128
ARG D 482
GLY D 483
THR D 500
GLU D 501
CPF G 101
5BTC_G_CPFG102 5btc CPF

DB00537
(Ciprofloxacin)
Mycobacterium
tuberculosis;
synthetic
construct
DNA GYRASE SUBUNIT
A;
DNA GYRASE SUBUNIT
B;
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC
PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
no annotation
6 SER A  90
ARG C 128
ARG B 482
GLY B 483
THR B 500
GLU B 501
CPF G 102