DRUG BINDING INTERFACES MAPPED TO 'DB00396'
DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1A28_A_STRA1 | 1a28 | STR DB00396(Progesterone) | Homo sapiens | PROGESTERONERECEPTOR | PF00104(Hormone_recep) | 14 | LEU A 718ASN A 719LEU A 721GLN A 725MET A 756MET A 759ARG A 766LEU A 797MET A 801TYR A 890CYS A 891THR A 894PHE A 905MET A 909 | STR A 1 |
1A28_B_STRB2 | 1a28 | STR DB00396(Progesterone) | Homo sapiens | PROGESTERONERECEPTOR | no annotation | 14 | LEU B 715LEU B 718ASN B 719LEU B 721GLN B 725MET B 756MET B 759ARG B 766LEU B 797MET B 801TYR B 890CYS B 891THR B 894MET B 909 | STR B 2 |
1DBB_H_STRH229 | 1dbb | STR DB00396(Progesterone) | Mus musculus | IGG1-KAPPA DB3 FAB(HEAVY CHAIN);IGG1-KAPPA DB3 FAB(LIGHT CHAIN) | PF07654(C1-set)PF07686(V-set) | 8 | HIS L 27GLY H 33ASN H 35TRP H 50VAL L 94GLY H 95TYR H 97TRP H 100 | STR H 229 |
1H60_A_STRA500 | 1h60 | STR DB00396(Progesterone) | Enterobactercloacae | PENTAERYTHRITOLTETRANITRATEREDUCTASE | PF00724(Oxidored_FMN) | 9 | THR A 26TYR A 68ARG A 142HIS A 181HIS A 184TYR A 186GLN A 241LEU A 275TYR A 351 | STR A 500 |
1MRQ_A_STRA501 | 1mrq | STR DB00396(Progesterone) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C1 | PF00248(Aldo_ket_red) | 11 | TYR A 24LEU A 54TYR A 55GLU A 127VAL A 128ILE A 129HIS A 222GLU A 224TRP A 227LEU A 306LEU A 308 | STR A 501 |
1W0F_A_STRA1499 | 1w0f | STR DB00396(Progesterone) | Homo sapiens | CYTOCHROME P450 3A4 | PF00067(p450) | 4 | PHE A 213ASP A 217PHE A 219VAL A 240 | STR A1499 |
1YA3_A_STRA1001 | 1ya3 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | PF00104(Hormone_recep) | 16 | LEU A 766LEU A 769ASN A 770LEU A 772ALA A 773GLN A 776MET A 807LEU A 810SER A 811LEU A 814ARG A 817MET A 845MET A 852LEU A 938CYS A 942THR A 945 | STR A1001 |
1YA3_B_STRB2001 | 1ya3 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | no annotation | 15 | LEU B 766LEU B 769ASN B 770ALA B 773GLN B 776MET B 807LEU B 810SER B 811LEU B 814ARG B 817MET B 845MET B 852LEU B 938CYS B 942THR B 945 | STR B2001 |
1YA3_C_STRC3001 | 1ya3 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | no annotation | 14 | LEU C 766LEU C 769ASN C 770LEU C 772ALA C 773GLN C 776MET C 807LEU C 810LEU C 814ARG C 817MET C 845LEU C 938CYS C 942THR C 945 | STR C3001 |
2AA5_A_STRA301 | 2aa5 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | PF00104(Hormone_recep) | 14 | LEU A 769ASN A 770LEU A 772ALA A 773GLN A 776TRP A 806MET A 807SER A 810LEU A 814ARG A 817MET A 845MET A 852CYS A 942THR A 945 | STR A 301 |
2AA5_B_STRB302 | 2aa5 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | no annotation | 14 | LEU B 766LEU B 769ASN B 770LEU B 772ALA B 773GLN B 776MET B 807SER B 810LEU B 814ARG B 817MET B 845MET B 852CYS B 942THR B 945 | STR B 302 |
2AA6_A_STRA401 | 2aa6 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | PF00104(Hormone_recep) | 13 | LEU A 769ASN A 770LEU A 772ALA A 773GLN A 776MET A 807LEU A 810LEU A 814ARG A 817MET A 845MET A 852CYS A 942THR A 945 | STR A 401 |
2AA6_B_STRB402 | 2aa6 | STR DB00396(Progesterone) | Homo sapiens | MINERALOCORTICOIDRECEPTOR | no annotation | 14 | LEU B 769ASN B 770LEU B 772ALA B 773GLN B 776MET B 807LEU B 810LEU B 814ARG B 817MET B 845MET B 852LEU B 938CYS B 942THR B 945 | STR B 402 |
2ABA_A_STRA1500 | 2aba | STR DB00396(Progesterone) | Enterobactercloacae | PENTAERYTHRITOLTETRANITRATEREDUCTASE | PF00724(Oxidored_FMN) | 9 | THR A 26TYR A 68SER A 132ARG A 142HIS A 181HIS A 184TYR A 186GLN A 241TYR A 351 | STR A1500 |
2HZQ_A_STRA300 | 2hzq | STR DB00396(Progesterone) | Homo sapiens | APOLIPOPROTEIN D | PF08212(Lipocalin_2) | 7 | THR A 34ALA A 44TYR A 46ASN A 58PHE A 89TRP A 127LEU A 129 | STR A 300 |
2O5Y_H_STRH249 | 2o5y | STR DB00396(Progesterone) | Homo sapiens;Mus musculus | CHIMERIC ANTIBODYFAB 1E9-DB3 | PF07654(C1-set)PF07686(V-set) | 7 | ASN H 35TRP H 50SER L 91GLY H 95THR H 97MET H 100TRP H 100 | STR H 249 |
3COT_A_STRA1501 | 3cot | STR DB00396(Progesterone) | Homo sapiens | 3-OXO-5-BETA-STEROID4-DEHYDROGENASE | PF00248(Aldo_ket_red) | 7 | TYR A 26TYR A 58GLU A 120TYR A 132TRP A 140TRP A 230TRP A 314 | STR A1501 |
3COT_B_STRB1500 | 3cot | STR DB00396(Progesterone) | Homo sapiens | 3-OXO-5-BETA-STEROID4-DEHYDROGENASE | no annotation | 10 | TYR B 26TYR B 58LYS B 87TRP B 89GLU B 120TYR B 132TRP B 140TRP B 230LEU B 311TRP B 314 | STR B1500 |
4BB2_B_STRB1384 | 4bb2 | STR DB00396(Progesterone) | Homo sapiens | CORTICOSTEROID-BINDING GLOBULIN | PF00079(Serpin) | 11 | ALA A 18SER A 19GLN A 232THR A 240PHE A 242ARG A 260ILE A 263ASN A 264SER A 267HIS B 368TRP B 371 | STR B1384 |
4FN9_A_STRA301 | 4fn9 | STR DB00396(Progesterone) | - | STEROID RECEPTOR 2 | PF00104(Hormone_recep) | 14 | LEU A 31LEU A 34ASN A 35LEU A 37ALA A 38GLN A 41MET A 72MET A 75ALA A 76MET A 79ARG A 82MET A 110CYS A 207THR A 210 | STR A 301 |
4FN9_B_STRB301 | 4fn9 | STR DB00396(Progesterone) | - | STEROID RECEPTOR 2 | no annotation | 13 | LEU B 31LEU B 34ASN B 35LEU B 37ALA B 38GLN B 41TRP B 71MET B 72MET B 75MET B 79ARG B 82MET B 110THR B 210 | STR B 301 |
4J6C_A_STRA501 | 4j6c | STR DB00396(Progesterone) | Nocardiafarcinica | CYTOCHROME P450MONOOXYGENASE | PF00067(p450) | 11 | MET A 84PHE A 92PHE A 179GLN A 239ALA A 240ALA A 243ALA A 244THR A 248VAL A 291LEU A 294GLN A 398 | STR A 501 |
4J6C_B_STRB503 | 4j6c | STR DB00396(Progesterone) | Nocardiafarcinica | CYTOCHROME P450MONOOXYGENASE | no annotation | 10 | MET B 84PHE B 179GLN B 239ALA B 240ALA B 243ALA B 244THR B 248VAL B 291LEU B 294GLN B 398 | STR B 503 |
4L1W_A_STRA402 | 4l1w | STR DB00396(Progesterone) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 | PF00248(Aldo_ket_red) | 7 | TYR A 24VAL A 128ILE A 129HIS A 222TRP A 227LEU A 306LEU A 308 | STR A 402 |
4L1W_B_STRB402 | 4l1w | STR DB00396(Progesterone) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 | no annotation | 6 | TYR B 24VAL B 54VAL B 128ILE B 129TRP B 227LEU B 308 | STR B 402 |
4L1X_A_STRA402 | 4l1x | STR DB00396(Progesterone) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 | PF00248(Aldo_ket_red) | 8 | TYR A 24LEU A 54TYR A 55VAL A 128HIS A 222TRP A 227LEU A 306LEU A 308 | STR A 402 |
4L1X_B_STRB402 | 4l1x | STR DB00396(Progesterone) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 | no annotation | 9 | TYR B 24TYR B 55VAL B 128ILE B 129HIS B 222GLU B 224TRP B 227LEU B 306LEU B 308 | STR B 402 |
4LTW_A_STRA301 | 4ltw | STR DB00396(Progesterone) | - | ANCESTRAL STEROIDRECEPTOR 2 | PF00104(Hormone_recep) | 20 | LEU A 31LEU A 34ASN A 35LEU A 37ALA A 38GLN A 41TRP A 71MET A 72MET A 75ALA A 76MET A 79ARG A 82MET A 110MET A 117LEU A 203PHE A 206CYS A 207THR A 210VAL A 219PHE A 221 | STR A 301 |
4NKX_A_STRA601 | 4nkx | STR DB00396(Progesterone) | Homo sapiens | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE | PF00067(p450) | 18 | LEU A 105ALA A 113PHE A 114ASN A 202ILE A 205ILE A 206LEU A 209ARG A 239ASP A 298GLY A 301ALA A 302GLU A 305THR A 306VAL A 366ALA A 367ILE A 371VAL A 482VAL A 483 | STR A 601 |
4NKX_B_STRB601 | 4nkx | STR DB00396(Progesterone) | Homo sapiens | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE | no annotation | 17 | LEU B 105ALA B 113PHE B 114ASN B 202ILE B 205ILE B 206LEU B 209ASP B 298GLY B 301ALA B 302GLU B 305THR B 306VAL B 366ALA B 367ILE B 371VAL B 482VAL B 483 | STR B 601 |
4NKX_C_STRC601 | 4nkx | STR DB00396(Progesterone) | Homo sapiens | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE | no annotation | 17 | LEU C 105ALA C 113PHE C 114ASN C 202ILE C 205ILE C 206ARG C 239ASP C 298GLY C 301ALA C 302GLU C 305THR C 306VAL C 366ALA C 367ILE C 371VAL C 482VAL C 483 | STR C 601 |
4NKX_D_STRD601 | 4nkx | STR DB00396(Progesterone) | Homo sapiens | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE | no annotation | 17 | LEU D 105ALA D 113PHE D 114ASN D 202ILE D 205ILE D 206ARG D 239ASP D 298GLY D 301ALA D 302GLU D 305THR D 306VAL D 366ALA D 367ILE D 371VAL D 482VAL D 483 | STR D 601 |
4R21_A_STRA601 | 4r21 | STR DB00396(Progesterone) | Danio rerio | CYTOCHROME P450FAMILY 17POLYPEPTIDE 2 | PF00067(p450) | 6 | ALA A 120ILE A 212GLY A 301SER A 367ILE A 371VAL A 480 | STR A 601 |
4R21_B_STRB601 | 4r21 | STR DB00396(Progesterone) | Danio rerio | CYTOCHROME P450FAMILY 17POLYPEPTIDE 2 | no annotation | 9 | ALA B 120ILE B 212VAL B 213GLY B 301ALA B 302THR B 306SER B 367ILE B 371VAL B 480 | STR B 601 |
4Y8W_A_STRA604 | 4y8w | STR DB00396(Progesterone) | Homo sapiens | CYTOCHROME P45021-HYDROXYLASE | PF00067(p450) | 13 | VAL A 101ASP A 107SER A 109VAL A 198LEU A 199TRP A 202ARG A 234ASP A 288ILE A 291GLY A 292VAL A 360LEU A 364VAL A 470 | STR A 604 |
4Y8W_B_STRB603 | 4y8w | STR DB00396(Progesterone) | Homo sapiens | CYTOCHROME P45021-HYDROXYLASE | no annotation | 13 | VAL B 101ASP B 107SER B 109VAL B 198LEU B 199TRP B 202ARG B 234VAL B 287ASP B 288ILE B 291GLY B 292VAL B 360LEU B 364 | STR B 603 |
4Y8W_C_STRC603 | 4y8w | STR DB00396(Progesterone) | Homo sapiens | CYTOCHROME P45021-HYDROXYLASE | no annotation | 15 | VAL C 101ASP C 107SER C 109LEU C 110VAL C 198LEU C 199TRP C 202ILE C 231ARG C 234VAL C 287ASP C 288ILE C 291GLY C 292VAL C 360LEU C 364 | STR C 603 |
5A1R_A_STRA600 | 5a1r | STR DB00396(Progesterone) | Homo sapiens | CYTOCHROME P450 3A4 | PF00067(p450) | 5 | PHE A 213ASP A 217PHE A 219PHE A 220VAL A 240 | STR A 600 |
5LUR_A_STRA201 | 5lur | STR DB00396(Progesterone) | Gallus gallus | AVIDIN | PF01382(Avidin) | 10 | MET A 14HIS A 16TYR A 33VAL A 37TRP A 70PHE A 72THR A 77PHE A 79TRP A 97ASN A 118 | STR A 201 |
5LUR_B_STRB201 | 5lur | STR DB00396(Progesterone) | Gallus gallus | AVIDIN | no annotation | 11 | MET B 14HIS B 16TYR B 33ALA B 35VAL B 37TRP B 70PHE B 72THR B 77PHE B 79TRP B 97ASN B 118 | STR B 201 |
5MLM_A_STRA401 | 5mlm | STR DB00396(Progesterone) | - | - | no annotation | 13 | ARG A 146LYS A 147MET A 150PHE A 153ILE A 156ASN A 205MET A 215ALA A 243SER A 248VAL A 347ILE A 350CYS A 352PRO A 353 | STR A 401 |
6F88_A_STRA502 | 6f88 | STR DB00396(Progesterone) | Sorangiumcellulosum | CYTOCHROME P450CYP260A1 | no annotation | 6 | PHE A 64LEU A 69ALA A 74SER A 225THR A 233ASN A 276 | STR A 502 |
6F88_B_STRB502 | 6f88 | STR DB00396(Progesterone) | Sorangiumcellulosum | CYTOCHROME P450CYP260A1 | no annotation | 6 | LEU B 69ALA B 74LEU B 159SER B 225THR B 233ASN B 276 | STR B 502 |
6F8C_A_STRA502 | 6f8c | STR DB00396(Progesterone) | Sorangiumcellulosum | CYTOCHROME P450CYP260A1 | no annotation | 6 | ALA A 74SER A 225GLY A 229THR A 233ILE A 276PHE A 277 | STR A 502 |
6F8C_B_STRB502 | 6f8c | STR DB00396(Progesterone) | Sorangiumcellulosum | CYTOCHROME P450CYP260A1 | no annotation | 8 | ALA B 74LEU B 159SER B 225LEU B 228GLY B 229THR B 233ILE B 276PHE B 277 | STR B 502 |
6GSD_A_STRA401 | 6gsd | STR DB00396(Progesterone) | Plantago major | PROGESTERONE5-BETA-REDUCTASE | None | 14 | ARG A 146LYS A 147VAL A 150PHE A 153ILE A 156TYR A 179ASN A 205MET A 215SER A 248TRP A 284VAL A 347ILE A 350CYS A 352PRO A 353 | STR A 401 |