DRUG BINDING INTERFACES MAPPED TO 'DB00257'

List of Binding Interfaces

(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
2XFH_A_CL6A1413 2xfh CL6

DB00257
(Clotrimazole)
Saccharopolyspora
erythraea
ERYTHROMYCIN B/D
C-12 HYDROXYLASE
PF00067
(p450)
6 HIS A  88
GLN A 173
ALA A 237
ALA A 241
THR A 245
PHE A 288
CL6 A1413
2XFH_A_CL6A1414 2xfh CL6

DB00257
(Clotrimazole)
Saccharopolyspora
erythraea
ERYTHROMYCIN B/D
C-12 HYDROXYLASE
PF00067
(p450)
8 MET A  86
HIS A  88
LEU A 169
GLN A 173
ILE A 186
LEU A 190
THR A 236
LEU A 240
CL6 A1414
3MDV_A_CL6A506 3mdv CL6

DB00257
(Clotrimazole)
Homo sapiens CHOLESTEROL
24-HYDROXYLASE
PF00067
(p450)
9 LEU A 112
PHE A 121
VAL A 126
LEU A 219
ILE A 301
ALA A 302
GLU A 305
ALA A 474
THR A 475
CL6 A 506
3MDV_B_CL6B506 3mdv CL6

DB00257
(Clotrimazole)
Homo sapiens CHOLESTEROL
24-HYDROXYLASE
no annotation 12 LEU B 112
PHE B 121
VAL B 126
LEU B 219
THR B 298
ILE B 301
ALA B 302
GLU B 305
THR B 306
ALA B 367
ALA B 474
THR B 475
CL6 B 506
4XE3_A_CL6A502 4xe3 CL6

DB00257
(Clotrimazole)
Streptomyces
antibioticus
CYTOCHROME P-450 PF00067
(p450)
5 LEU A  94
ALA A 244
THR A 248
VAL A 291
ILE A 397
CL6 A 502
4XE3_B_CL6B502 4xe3 CL6

DB00257
(Clotrimazole)
Streptomyces
antibioticus
CYTOCHROME P-450 no annotation 5 LEU B  94
ALA B 244
THR B 248
VAL B 291
ILE B 397
CL6 B 502