DRUG BINDING INTERFACES MAPPED TO 'DB00152'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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All hits from Homo Sapiens
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1IG0_A_VIBA702
1ig0
VIB
DB00152(Thiamine)
Saccharomycescerevisiae
THIAMINPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
10
CYS B 5GLN A 122TYR A 123THR A 125TRP B 270VAL B 272TRP B 275SER B 285SER B 287ASN B 288
VIB A 702
1IG0_B_VIBB701
1ig0
VIB
DB00152(Thiamine)
Saccharomycescerevisiae
THIAMINPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
9
GLN B 122TYR B 123THR B 125TRP A 270VAL A 272TRP A 275SER A 285SER A 287ASN A 288
VIB B 701
1IG3_A_VIBA502
1ig3
VIB
DB00152(Thiamine)
Mus musculus
THIAMINPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
8
GLN B 116ASP B 117THR B 119TRP A 222LEU A 224SER A 236SER A 238ASN A 239
VIB A 502
1IG3_B_VIBB501
1ig3
VIB
DB00152(Thiamine)
Mus musculus
THIAMINPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
7
GLN A 116ASP A 117TRP B 222LEU B 224SER B 236SER B 238ASN B 239
VIB B 501
1SBR_A_VIBA501
1sbr
VIB
DB00152(Thiamine)
Bacillus subtilis
YKOF
PF07615(Ykof)
8
PHE A 15SER A 16LEU A 17ILE A 25ILE A 28LYS A 29THR A 44THR A 49
VIB A 501
1SBR_A_VIBA502
1sbr
VIB
DB00152(Thiamine)
Bacillus subtilis
YKOF
PF07615(Ykof)no annotation
6
CYS B 86PHE A 119ALA A 120LEU A 121ILE A 133SER A 154
VIB A 502
1SBR_B_VIBB503
1sbr
VIB
DB00152(Thiamine)
Bacillus subtilis
YKOF
no annotation
7
PHE B 15SER B 16ILE B 25ILE B 28LYS B 29THR B 44THR B 49
VIB B 503
1SBR_B_VIBB504
1sbr
VIB
DB00152(Thiamine)
Bacillus subtilis
YKOF
PF07615(Ykof)no annotation
6
PRO A 87PHE B 119LEU B 121ILE B 133SER B 154HIS A 180
VIB B 504
2HH9_A_VIBA702
2hh9
VIB
DB00152(Thiamine)
Candida albicans
THIAMINPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
9
VAL B 11ASP A 113GLN A 138TYR A 139TYR B 285MET B 287SER B 299SER B 301ASN B 302
VIB A 702
2HH9_B_VIBB701
2hh9
VIB
DB00152(Thiamine)
Candida albicans
THIAMINPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
9
VAL A 11ASP B 113GLN B 138TYR B 139TYR A 285MET A 287SER A 299SER A 301ASN A 302
VIB B 701
2LH8_A_VIBA1
2lh8
VIB
DB00152(Thiamine)
Mesocricetusauratus
MAJOR PRION PROTEIN
PF00377(Prion)
6
PRO A 47MET A 48HIS A 50ASP A 54ASP A 57TYR A 60
VIB A 1
3LM8_A_VIBA223
3lm8
VIB
DB00152(Thiamine)
Bacillus subtilis
THIAMINEPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
7
ASP C 78THR C 80TYR A 174LEU A 176LEU A 187SER A 190ASN A 191
VIB A 223
3LM8_B_VIBB223
3lm8
VIB
DB00152(Thiamine)
Bacillus subtilis
THIAMINEPYROPHOSPHOKINASE
no annotation
7
THR D 80TYR B 174LEU B 176LEU B 187CYS B 188SER B 190ASN B 191
VIB B 223
3LM8_C_VIBC223
3lm8
VIB
DB00152(Thiamine)
Bacillus subtilis
THIAMINEPYROPHOSPHOKINASE
PF04263(TPK_catalytic)PF04265(TPK_B1_binding)no annotation
8
LYS A 77ASP A 78TYR C 174LEU C 176LEU C 187CYS C 188SER C 190ASN C 191
VIB C 223
3LM8_D_VIBD223
3lm8
VIB
DB00152(Thiamine)
Bacillus subtilis
THIAMINEPYROPHOSPHOKINASE
no annotation
8
ASP B 78HIS B 109TYR D 174LEU D 176LEU D 187CYS D 188SER D 190ASN D 191
VIB D 223
3MYU_A_VIBA500
3myu
VIB
DB00152(Thiamine)
Mycoplasmagenitalium
HIGH AFFINITYTRANSPORT SYSTEMPROTEIN P37
PF06646(Mycoplasma_p37)
10
ASP A 41HIS A 42ASN A 95TYR A 176ASP A 269TRP A 275TYR A 307ASP A 308ILE A 343GLY A 344
VIB A 500
3MYU_B_VIBB500
3myu
VIB
DB00152(Thiamine)
Mycoplasmagenitalium
HIGH AFFINITYTRANSPORT SYSTEMPROTEIN P37
no annotation
10
ASP B 41HIS B 42ASN B 161TYR B 176ASP B 269TRP B 275TYR B 307ASP B 308ILE B 343GLY B 344
VIB B 500
3RLB_A_VIBA191
3rlb
VIB
DB00152(Thiamine)
Lactococcuslactis
THIT
PF09515(Thia_YuaJ)
10
TRP A 34GLU A 38GLU A 84TYR A 85HIS A 125GLY A 129TRP A 133TYR A 146VAL A 150ASN A 151
VIB A 191
3RLB_B_VIBB187
3rlb
VIB
DB00152(Thiamine)
Lactococcuslactis
THIT
no annotation
12
TRP B 34ILE B 36GLU B 38GLU B 84TYR B 85TYR B 122HIS B 125GLY B 129TRP B 133TYR B 146VAL B 150ASN B 151
VIB B 187
4KYS_A_VIBA501
4kys
VIB
DB00152(Thiamine)
Clostridiumbotulinum
THIAMINEPYRIDINYLASE I
PF01547(SBP_bac_1)
10
TYR A 46TYR A 80ASP A 94SER A 143THR A 193TYR A 269GLU A 271TYR A 300ASP A 302LEU A 348
VIB A 501
4KYS_B_VIBB501
4kys
VIB
DB00152(Thiamine)
Clostridiumbotulinum
THIAMINEPYRIDINYLASE I
no annotation
11
TYR B 46TYR B 80ASP B 94ILE B 141SER B 143THR B 193TYR B 269GLU B 271TYR B 300ASP B 302LEU B 348
VIB B 501
4NMY_A_VIBA401
4nmy
VIB
DB00152(Thiamine)
Clostridioidesdifficile
ABC-TYPE TRANSPORTSYSTEM,EXTRACELLULARSOLUTE-BINDINGPROTEIN
PF09084(NMT1)
11
TRP A 12ASN A 15TYR A 62GLU A 64SER A 90TRP A 114TRP A 158PHE A 160TRP A 163TYR A 189THR A 191
VIB A 401
4NMY_B_VIBB401
4nmy
VIB
DB00152(Thiamine)
Clostridioidesdifficile
ABC-TYPE TRANSPORTSYSTEM,EXTRACELLULARSOLUTE-BINDINGPROTEIN
no annotation
10
TRP B 12ASN B 15TYR B 62GLU B 64SER B 90TRP B 114TRP B 158TRP B 163TYR B 189THR B 191
VIB B 401
5EDL_A_VIBA201
5edl
VIB
DB00152(Thiamine)
Bacillus subtilis
PUTATIVEHMP/THIAMINEPERMEASE PROTEINYKOE
PF09819(ABC_cobalt)
14
TYR A 23THR A 27TYR A 42TYR A 46TRP A 49GLU A 70GLU A 77VAL A 88ILE A 91GLN A 95ASP A 131SER A 135TYR A 137ARG A 152
VIB A 201
[["1IG0_A_VIBA702","1ig0","VIB","DB00152(Thiamine)","Saccharomyces cerevisiae","THIAMIN PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",10,"CYS B 5;GLN A 122;TYR A 123;THR A 125;TRP B 270;VAL B 272;TRP B 275;SER B 285;SER B 287;ASN B 288","VIB A 702\r"],["1IG0_B_VIBB701","1ig0","VIB","DB00152(Thiamine)","Saccharomyces cerevisiae","THIAMIN PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",9,"GLN B 122;TYR B 123;THR B 125;TRP A 270;VAL A 272;TRP A 275;SER A 285;SER A 287;ASN A 288","VIB B 701\r"],["1IG3_A_VIBA502","1ig3","VIB","DB00152(Thiamine)","Mus musculus","THIAMIN PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",8,"GLN B 116;ASP B 117;THR B 119;TRP A 222;LEU A 224;SER A 236;SER A 238;ASN A 239","VIB A 502\r"],["1IG3_B_VIBB501","1ig3","VIB","DB00152(Thiamine)","Mus musculus","THIAMIN PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",7,"GLN A 116;ASP A 117;TRP B 222;LEU B 224;SER B 236;SER B 238;ASN B 239","VIB B 501\r"],["1SBR_A_VIBA501","1sbr","VIB","DB00152(Thiamine)","Bacillus subtilis","YKOF","PF07615(Ykof)",8,"PHE A 15;SER A 16;LEU A 17;ILE A 25;ILE A 28;LYS A 29;THR A 44;THR A 49","VIB A 501\r"],["1SBR_A_VIBA502","1sbr","VIB","DB00152(Thiamine)","Bacillus subtilis","YKOF","PF07615(Ykof);no annotation",6,"CYS B 86;PHE A 119;ALA A 120;LEU A 121;ILE A 133;SER A 154","VIB A 502\r"],["1SBR_B_VIBB503","1sbr","VIB","DB00152(Thiamine)","Bacillus subtilis","YKOF","no annotation",7,"PHE B 15;SER B 16;ILE B 25;ILE B 28;LYS B 29;THR B 44;THR B 49","VIB B 503\r"],["1SBR_B_VIBB504","1sbr","VIB","DB00152(Thiamine)","Bacillus subtilis","YKOF","PF07615(Ykof);no annotation",6,"PRO A 87;PHE B 119;LEU B 121;ILE B 133;SER B 154;HIS A 180","VIB B 504\r"],["2HH9_A_VIBA702","2hh9","VIB","DB00152(Thiamine)","Candida albicans","THIAMIN PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",9,"VAL B 11;ASP A 113;GLN A 138;TYR A 139;TYR B 285;MET B 287;SER B 299;SER B 301;ASN B 302","VIB A 702\r"],["2HH9_B_VIBB701","2hh9","VIB","DB00152(Thiamine)","Candida albicans","THIAMIN PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",9,"VAL A 11;ASP B 113;GLN B 138;TYR B 139;TYR A 285;MET A 287;SER A 299;SER A 301;ASN A 302","VIB B 701\r"],["2LH8_A_VIBA1","2lh8","VIB","DB00152(Thiamine)","Mesocricetus auratus","MAJOR PRION PROTEIN","PF00377(Prion)",6,"PRO A 47;MET A 48;HIS A 50;ASP A 54;ASP A 57;TYR A 60","VIB A 1\r"],["3LM8_A_VIBA223","3lm8","VIB","DB00152(Thiamine)","Bacillus subtilis","THIAMINE PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",7,"ASP C 78;THR C 80;TYR A 174;LEU A 176;LEU A 187;SER A 190;ASN A 191","VIB A 223\r"],["3LM8_B_VIBB223","3lm8","VIB","DB00152(Thiamine)","Bacillus subtilis","THIAMINE PYROPHOSPHOKINASE","no annotation",7,"THR D 80;TYR B 174;LEU B 176;LEU B 187;CYS B 188;SER B 190;ASN B 191","VIB B 223\r"],["3LM8_C_VIBC223","3lm8","VIB","DB00152(Thiamine)","Bacillus subtilis","THIAMINE PYROPHOSPHOKINASE","PF04263(TPK_catalytic);PF04265(TPK_B1_binding);no annotation",8,"LYS A 77;ASP A 78;TYR C 174;LEU C 176;LEU C 187;CYS C 188;SER C 190;ASN C 191","VIB C 223\r"],["3LM8_D_VIBD223","3lm8","VIB","DB00152(Thiamine)","Bacillus subtilis","THIAMINE PYROPHOSPHOKINASE","no annotation",8,"ASP B 78;HIS B 109;TYR D 174;LEU D 176;LEU D 187;CYS D 188;SER D 190;ASN D 191","VIB D 223\r"],["3MYU_A_VIBA500","3myu","VIB","DB00152(Thiamine)","Mycoplasma genitalium","HIGH AFFINITY TRANSPORT SYSTEM PROTEIN P37","PF06646(Mycoplasma_p37)",10,"ASP A 41;HIS A 42;ASN A 95;TYR A 176;ASP A 269;TRP A 275;TYR A 307;ASP A 308;ILE A 343;GLY A 344","VIB A 500\r"],["3MYU_B_VIBB500","3myu","VIB","DB00152(Thiamine)","Mycoplasma genitalium","HIGH AFFINITY TRANSPORT SYSTEM PROTEIN P37","no annotation",10,"ASP B 41;HIS B 42;ASN B 161;TYR B 176;ASP B 269;TRP B 275;TYR B 307;ASP B 308;ILE B 343;GLY B 344","VIB B 500\r"],["3RLB_A_VIBA191","3rlb","VIB","DB00152(Thiamine)","Lactococcus lactis","THIT","PF09515(Thia_YuaJ)",10,"TRP A 34;GLU A 38;GLU A 84;TYR A 85;HIS A 125;GLY A 129;TRP A 133;TYR A 146;VAL A 150;ASN A 151","VIB A 191\r"],["3RLB_B_VIBB187","3rlb","VIB","DB00152(Thiamine)","Lactococcus lactis","THIT","no annotation",12,"TRP B 34;ILE B 36;GLU B 38;GLU B 84;TYR B 85;TYR B 122;HIS B 125;GLY B 129;TRP B 133;TYR B 146;VAL B 150;ASN B 151","VIB B 187\r"],["4KYS_A_VIBA501","4kys","VIB","DB00152(Thiamine)","Clostridium botulinum","THIAMINE PYRIDINYLASE I","PF01547(SBP_bac_1)",10,"TYR A 46;TYR A 80;ASP A 94;SER A 143;THR A 193;TYR A 269;GLU A 271;TYR A 300;ASP A 302;LEU A 348","VIB A 501\r"],["4KYS_B_VIBB501","4kys","VIB","DB00152(Thiamine)","Clostridium botulinum","THIAMINE PYRIDINYLASE I","no annotation",11,"TYR B 46;TYR B 80;ASP B 94;ILE B 141;SER B 143;THR B 193;TYR B 269;GLU B 271;TYR B 300;ASP B 302;LEU B 348","VIB B 501\r"],["4NMY_A_VIBA401","4nmy","VIB","DB00152(Thiamine)","Clostridioides difficile","ABC-TYPE TRANSPORT SYSTEM, EXTRACELLULAR SOLUTE-BINDING PROTEIN","PF09084(NMT1)",11,"TRP A 12;ASN A 15;TYR A 62;GLU A 64;SER A 90;TRP A 114;TRP A 158;PHE A 160;TRP A 163;TYR A 189;THR A 191","VIB A 401\r"],["4NMY_B_VIBB401","4nmy","VIB","DB00152(Thiamine)","Clostridioides difficile","ABC-TYPE TRANSPORT SYSTEM, EXTRACELLULAR SOLUTE-BINDING PROTEIN","no annotation",10,"TRP B 12;ASN B 15;TYR B 62;GLU B 64;SER B 90;TRP B 114;TRP B 158;TRP B 163;TYR B 189;THR B 191","VIB B 401\r"],["5EDL_A_VIBA201","5edl","VIB","DB00152(Thiamine)","Bacillus subtilis","PUTATIVE HMP\/THIAMINE PERMEASE PROTEIN YKOE","PF09819(ABC_cobalt)",14,"TYR A 23;THR A 27;TYR A 42;TYR A 46;TRP A 49;GLU A 70;GLU A 77;VAL A 88;ILE A 91;GLN A 95;ASP A 131;SER A 135;TYR A 137;ARG A 152","VIB A 201\r"]]