DRUG BINDING INTERFACES MAPPED TO 'DB00145'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1EQB_A_GLYA1292	1eqb	GLY DB00145 (Glycine)	Escherichia coli	SERINE HYDROXYMETHYLTRANSFE RASE	None PF00464 (SHMT)	8	SER A 35 TYR B 55 PHE B 65 HIS A 126 SER A 175 HIS A 203 LYS A 229 ARG A 363	GLY A1292
1EQB_B_GLYB2292	1eqb	GLY DB00145 (Glycine)	Escherichia coli	SERINE HYDROXYMETHYLTRANSFE RASE	None PF00464 (SHMT)	8	SER B 35 TYR A 55 PHE A 65 HIS B 126 SER B 175 HIS B 203 LYS B 229 ARG B 363	GLY B2292
1EQB_C_GLYC3292	1eqb	GLY DB00145 (Glycine)	Escherichia coli	SERINE HYDROXYMETHYLTRANSFE RASE	None	8	SER C 35 TYR D 55 PHE D 65 HIS C 126 SER C 175 HIS C 203 LYS C 229 ARG C 363	GLY C3292
1EQB_D_GLYD4292	1eqb	GLY DB00145 (Glycine)	Escherichia coli	SERINE HYDROXYMETHYLTRANSFE RASE	None	8	SER D 35 TYR C 55 PHE C 65 HIS D 126 SER D 175 HIS D 203 LYS D 229 ARG D 363	GLY D4292
2RLC_A_GLYA333	2rlc	GLY DB00145 (Glycine)	Clostridium perfringens	CHOLOYLGLYCINE HYDROLASE	PF02275 (CBAH)	3	ASN A 82 ASN A 175 ARG A 228	GLY A 333
2VMY_A_GLYA502	2vmy	GLY DB00145 (Glycine)	Geobacillus stearothermophilu s	SERINE HYDROXYMETHYLTRANSFE RASE	None PF00464 (SHMT)	7	SER A 31 TYR B 51 TYR B 61 HIS A 122 HIS A 200 LYS A 226 ARG A 357	GLY A 502
2VMY_B_GLYB502	2vmy	GLY DB00145 (Glycine)	Geobacillus stearothermophilu s	SERINE HYDROXYMETHYLTRANSFE RASE	None PF00464 (SHMT)	8	SER B 31 TYR A 51 TYR A 61 HIS B 122 SER B 172 HIS B 200 LYS B 226 ARG B 357	GLY B 502
2YS6_A_GLYA431	2ys6	GLY DB00145 (Glycine)	Geobacillus kaustophilus	PHOSPHORIBOSYLGLYCIN AMIDE SYNTHETASE	PF01071 (GARS_A) PF02843 (GARS_C) PF02844 (GARS_N)	8	ASP A 212 LYS A 214 TYR A 269 ASN A 285 ARG A 287 GLY A 289 PRO A 291 GLU A 292	GLY A 431
2Z0A_A_GLYA73	2z0a	GLY DB00145 (Glycine)	Influenza A virus	NONSTRUCTURAL PROTEIN 1	PF00600 (Flu_NS1)	5	GLN A 10 ALA A 60 GLN A 63 ILE A 64 ARG A 67	GLY A 73
2Z0A_A_GLYA74	2z0a	GLY DB00145 (Glycine)	Influenza A virus	NONSTRUCTURAL PROTEIN 1	PF00600 (Flu_NS1)	4	LYS A 20 LEU A 36 ARG A 37 GLN A 40	GLY A 74
2Z0A_C_GLYC73	2z0a	GLY DB00145 (Glycine)	Influenza A virus	NONSTRUCTURAL PROTEIN 1	None	4	ASP C 12 ASP C 39 SER C 42 ARG C 46	GLY C 73
2Z0A_D_GLYD73	2z0a	GLY DB00145 (Glycine)	Influenza A virus	NONSTRUCTURAL PROTEIN 1	None	4	ARG C 35 ASP D 39 SER D 42 ARG D 46	GLY D 73
2ZT7_A_GLYA1300	2zt7	GLY DB00145 (Glycine)	Homo sapiens	GLYCYL-TRNA SYNTHETASE	PF00587 (HGTP_anticodon) PF03129 (tRNA-synt_2b)	7	GLU A 245 ARG A 277 GLU A 296 TYR A 386 ARG A 410 GLU A 522 SER A 524	GLY A1300
3PGY_A_GLYA510	3pgy	GLY DB00145 (Glycine)	Staphylococcus aureus	SERINE HYDROXYMETHYLTRANSFE RASE	None PF00464 (SHMT)	6	GLU A 27 ILE A 29 GLU A 32 PHE A 34 ASN B 49 ALA A 363	GLY A 510
3PGY_B_GLYB509	3pgy	GLY DB00145 (Glycine)	Staphylococcus aureus	SERINE HYDROXYMETHYLTRANSFE RASE	None	4	PHE B 34 THR B 366 LEU B 410 TYR B 411	GLY B 509
3PGY_B_GLYB511	3pgy	GLY DB00145 (Glycine)	Staphylococcus aureus	SERINE HYDROXYMETHYLTRANSFE RASE	None	5	SER B 334 GLU B 391 LEU B 394 GLN B 395 LYS B 398	GLY B 511
3RGL_A_GLYA301	3rgl	GLY DB00145 (Glycine)	Campylobacter jejuni	GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT	PF02091 (tRNA-synt_2e)	8	ALA A 31 GLY A 32 THR A 33 ARG A 58 GLN A 76 GLN A 78 GLU A 156 THR A 158	GLY A 301
4KR3_A_GLYA701	4kr3	GLY DB00145 (Glycine)	Homo sapiens	GLYCINE--TRNA LIGASE	PF00587 (HGTP_anticodon) PF03129 (tRNA-synt_2b)	6	GLU A 245 ARG A 277 GLU A 296 ARG A 410 GLU A 522 SER A 524	GLY A 701
4YSH_B_GLYB401	4ysh	GLY DB00145 (Glycine)	Geobacillus kaustophilus	GLYCINE OXIDASE	None	6	PHE B 247 LYS B 249 GLY B 251 TYR B 253 ALA B 266 ARG B 336	GLY B 401
4YSH_B_GLYB402	4ysh	GLY DB00145 (Glycine)	Geobacillus kaustophilus	GLYCINE OXIDASE	None	5	MET B 49 GLU B 55 TYR B 253 ARG B 309 ARG B 336	GLY B 402
4ZXI_A_GLYA1402	4zxi	GLY DB00145 (Glycine)	Acinetobacter baumannii	TYROCIDINE SYNTHETASE 3	PF00501 (PP-binding) PF00550 (Thioesterase) PF00668 (AMP-binding_C) PF00975 (AMP-binding) PF13193 (Condensation)	7	PHE A 669 ASP A 670 ILE A 671 GLY A 739 THR A 764 TRP A 769 LYS A 952	GLY A1402
5HHJ_A_GLYA403	5hhj	GLY DB00145 (Glycine)	Roseburia intestinalis	RETRON-TYPE REVERSE TRANSCRIPTASE	PF00078 (RVT_1)	4	LEU A 28 LEU A 56 GLY A 60 GLU A 61	GLY A 403
5HHJ_A_GLYA404	5hhj	GLY DB00145 (Glycine)	Roseburia intestinalis	RETRON-TYPE REVERSE TRANSCRIPTASE	PF00078 (RVT_1)	4	TYR A 55 ASN A 59 ILE A 63 GLN A 66	GLY A 404
5HHJ_B_GLYB404	5hhj	GLY DB00145 (Glycine)	Roseburia intestinalis	RETRON-TYPE REVERSE TRANSCRIPTASE	None	4	GLN B 104 ALA B 107 GLN B 108 THR B 111	GLY B 404
6AF6_A_GLYA507	6af6	GLY DB00145 (Glycine)	Serratia sp. ATCC 39006	L-PROLYL-[PEPTIDYL-C ARRIER PROTEIN] DEHYDROGENASE	PF00441 (Acyl-CoA_dh_M) PF02770 (Acyl-CoA_dh_1) PF02771 (Acyl-CoA_dh_N)	3	TYR A 137 HIS A 238 MET A 241	GLY A 507
6DWD_A_GLYA715	6dwd	GLY DB00145 (Glycine)	Homo sapiens	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1	None PF01966 (HD)	6	GLY A 357 ASN A 358 ASP A 361 SER C 368 ARG C 371 ARG C 372	GLY A 715
6DWD_A_GLYA717	6dwd	GLY DB00145 (Glycine)	Homo sapiens	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1	PF01966 (HD)	5	SER A 192 ARG A 194 ASP A 195 ARG A 290 LYS A 294	GLY A 717
6DWD_B_GLYB709	6dwd	GLY DB00145 (Glycine)	Homo sapiens	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1	None	5	GLY B 357 ASN B 358 ASP B 361 ARG D 371 ARG D 372	GLY B 709
6DWD_C_GLYC713	6dwd	GLY DB00145 (Glycine)	Homo sapiens	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1	None	3	GLN C 447 TYR C 450 ASN C 452	GLY C 713
6DWD_D_GLYD713	6dwd	GLY DB00145 (Glycine)	Homo sapiens	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1	None	3	ARG D 305 HIS D 517 ARG D 531	GLY D 713
6DWJ_B_GLYB710	6dwj	GLY DB00145 (Glycine)	Homo sapiens	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1	None	5	GLY D 357 ASN D 358 ASP D 361 ARG B 371 ARG B 372	GLY B 710
6MN8_A_GLYA607	6mn8	GLY DB00145 (Glycine)	Onchocerca volvulus	UNCHARACTERIZED PROTEIN	PF00587 (HGTP_anticodon) PF03129 (tRNA-synt_2b)	4	GLU A 379 ASP A 381 ARG A 383 TRP A 395	GLY A 607

[["1EQB_A_GLYA1292","1eqb","GLY","DB00145(Glycine)","Escherichia coli","SERINE HYDROXYMETHYLTRANSFERASE","None;PF00464(SHMT)",8,"SER A  35;TYR B  55;PHE B  65;HIS A 126;SER A 175;HIS A 203;LYS A 229;ARG A 363","GLY A1292\r"],["1EQB_B_GLYB2292","1eqb","GLY","DB00145(Glycine)","Escherichia coli","SERINE HYDROXYMETHYLTRANSFERASE","None;PF00464(SHMT)",8,"SER B  35;TYR A  55;PHE A  65;HIS B 126;SER B 175;HIS B 203;LYS B 229;ARG B 363","GLY B2292\r"],["1EQB_C_GLYC3292","1eqb","GLY","DB00145(Glycine)","Escherichia coli","SERINE HYDROXYMETHYLTRANSFERASE","None",8,"SER C  35;TYR D  55;PHE D  65;HIS C 126;SER C 175;HIS C 203;LYS C 229;ARG C 363","GLY C3292\r"],["1EQB_D_GLYD4292","1eqb","GLY","DB00145(Glycine)","Escherichia coli","SERINE HYDROXYMETHYLTRANSFERASE","None",8,"SER D  35;TYR C  55;PHE C  65;HIS D 126;SER D 175;HIS D 203;LYS D 229;ARG D 363","GLY D4292\r"],["2RLC_A_GLYA333","2rlc","GLY","DB00145(Glycine)","Clostridium perfringens","CHOLOYLGLYCINE HYDROLASE","PF02275(CBAH)",3,"ASN A  82;ASN A 175;ARG A 228","GLY A 333\r"],["2VMY_A_GLYA502","2vmy","GLY","DB00145(Glycine)","Geobacillus stearothermophilus","SERINE HYDROXYMETHYLTRANSFERASE","None;PF00464(SHMT)",7,"SER A  31;TYR B  51;TYR B  61;HIS A 122;HIS A 200;LYS A 226;ARG A 357","GLY A 502\r"],["2VMY_B_GLYB502","2vmy","GLY","DB00145(Glycine)","Geobacillus stearothermophilus","SERINE HYDROXYMETHYLTRANSFERASE","None;PF00464(SHMT)",8,"SER B  31;TYR A  51;TYR A  61;HIS B 122;SER B 172;HIS B 200;LYS B 226;ARG B 357","GLY B 502\r"],["2YS6_A_GLYA431","2ys6","GLY","DB00145(Glycine)","Geobacillus kaustophilus","PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE","PF01071(GARS_A);PF02843(GARS_C);PF02844(GARS_N)",8,"ASP A 212;LYS A 214;TYR A 269;ASN A 285;ARG A 287;GLY A 289;PRO A 291;GLU A 292","GLY A 431\r"],["2Z0A_A_GLYA73","2z0a","GLY","DB00145(Glycine)","Influenza A virus","NONSTRUCTURAL PROTEIN 1","PF00600(Flu_NS1)",5,"GLN A  10;ALA A  60;GLN A  63;ILE A  64;ARG A  67","GLY A  73\r"],["2Z0A_A_GLYA74","2z0a","GLY","DB00145(Glycine)","Influenza A virus","NONSTRUCTURAL PROTEIN 1","PF00600(Flu_NS1)",4,"LYS A  20;LEU A  36;ARG A  37;GLN A  40","GLY A  74\r"],["2Z0A_C_GLYC73","2z0a","GLY","DB00145(Glycine)","Influenza A virus","NONSTRUCTURAL PROTEIN 1","None",4,"ASP C  12;ASP C  39;SER C  42;ARG C  46","GLY C  73\r"],["2Z0A_D_GLYD73","2z0a","GLY","DB00145(Glycine)","Influenza A virus","NONSTRUCTURAL PROTEIN 1","None",4,"ARG C  35;ASP D  39;SER D  42;ARG D  46","GLY D  73\r"],["2ZT7_A_GLYA1300","2zt7","GLY","DB00145(Glycine)","Homo sapiens","GLYCYL-TRNA SYNTHETASE","PF00587(HGTP_anticodon);PF03129(tRNA-synt_2b)",7,"GLU A 245;ARG A 277;GLU A 296;TYR A 386;ARG A 410;GLU A 522;SER A 524","GLY A1300\r"],["3PGY_A_GLYA510","3pgy","GLY","DB00145(Glycine)","Staphylococcus aureus","SERINE HYDROXYMETHYLTRANSFERASE","None;PF00464(SHMT)",6,"GLU A  27;ILE A  29;GLU A  32;PHE A  34;ASN B  49;ALA A 363","GLY A 510\r"],["3PGY_B_GLYB509","3pgy","GLY","DB00145(Glycine)","Staphylococcus aureus","SERINE HYDROXYMETHYLTRANSFERASE","None",4,"PHE B  34;THR B 366;LEU B 410;TYR B 411","GLY B 509\r"],["3PGY_B_GLYB511","3pgy","GLY","DB00145(Glycine)","Staphylococcus aureus","SERINE HYDROXYMETHYLTRANSFERASE","None",5,"SER B 334;GLU B 391;LEU B 394;GLN B 395;LYS B 398","GLY B 511\r"],["3RGL_A_GLYA301","3rgl","GLY","DB00145(Glycine)","Campylobacter jejuni","GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT","PF02091(tRNA-synt_2e)",8,"ALA A  31;GLY A  32;THR A  33;ARG A  58;GLN A  76;GLN A  78;GLU A 156;THR A 158","GLY A 301\r"],["4KR3_A_GLYA701","4kr3","GLY","DB00145(Glycine)","Homo sapiens","GLYCINE--TRNA LIGASE","PF00587(HGTP_anticodon);PF03129(tRNA-synt_2b)",6,"GLU A 245;ARG A 277;GLU A 296;ARG A 410;GLU A 522;SER A 524","GLY A 701\r"],["4YSH_B_GLYB401","4ysh","GLY","DB00145(Glycine)","Geobacillus kaustophilus","GLYCINE OXIDASE","None",6,"PHE B 247;LYS B 249;GLY B 251;TYR B 253;ALA B 266;ARG B 336","GLY B 401\r"],["4YSH_B_GLYB402","4ysh","GLY","DB00145(Glycine)","Geobacillus kaustophilus","GLYCINE OXIDASE","None",5,"MET B  49;GLU B  55;TYR B 253;ARG B 309;ARG B 336","GLY B 402\r"],["4ZXI_A_GLYA1402","4zxi","GLY","DB00145(Glycine)","Acinetobacter baumannii","TYROCIDINE SYNTHETASE 3","PF00501(PP-binding);PF00550(Thioesterase);PF00668(AMP-binding_C);PF00975(AMP-binding);PF13193(Condensation)",7,"PHE A 669;ASP A 670;ILE A 671;GLY A 739;THR A 764;TRP A 769;LYS A 952","GLY A1402\r"],["5HHJ_A_GLYA403","5hhj","GLY","DB00145(Glycine)","Roseburia intestinalis","RETRON-TYPE REVERSE TRANSCRIPTASE","PF00078(RVT_1)",4,"LEU A  28;LEU A  56;GLY A  60;GLU A  61","GLY A 403\r"],["5HHJ_A_GLYA404","5hhj","GLY","DB00145(Glycine)","Roseburia intestinalis","RETRON-TYPE REVERSE TRANSCRIPTASE","PF00078(RVT_1)",4,"TYR A  55;ASN A  59;ILE A  63;GLN A  66","GLY A 404\r"],["5HHJ_B_GLYB404","5hhj","GLY","DB00145(Glycine)","Roseburia intestinalis","RETRON-TYPE REVERSE TRANSCRIPTASE","None",4,"GLN B 104;ALA B 107;GLN B 108;THR B 111","GLY B 404\r"],["6AF6_A_GLYA507","6af6","GLY","DB00145(Glycine)","Serratia sp. ATCC 39006","L-PROLYL-[PEPTIDYL-CARRIER PROTEIN] DEHYDROGENASE","PF00441(Acyl-CoA_dh_M);PF02770(Acyl-CoA_dh_1);PF02771(Acyl-CoA_dh_N)",3,"TYR A 137;HIS A 238;MET A 241","GLY A 507\r"],["6DWD_A_GLYA715","6dwd","GLY","DB00145(Glycine)","Homo sapiens","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","None;PF01966(HD)",6,"GLY A 357;ASN A 358;ASP A 361;SER C 368;ARG C 371;ARG C 372","GLY A 715\r"],["6DWD_A_GLYA717","6dwd","GLY","DB00145(Glycine)","Homo sapiens","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","PF01966(HD)",5,"SER A 192;ARG A 194;ASP A 195;ARG A 290;LYS A 294","GLY A 717\r"],["6DWD_B_GLYB709","6dwd","GLY","DB00145(Glycine)","Homo sapiens","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","None",5,"GLY B 357;ASN B 358;ASP B 361;ARG D 371;ARG D 372","GLY B 709\r"],["6DWD_C_GLYC713","6dwd","GLY","DB00145(Glycine)","Homo sapiens","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","None",3,"GLN C 447;TYR C 450;ASN C 452","GLY C 713\r"],["6DWD_D_GLYD713","6dwd","GLY","DB00145(Glycine)","Homo sapiens","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","None",3,"ARG D 305;HIS D 517;ARG D 531","GLY D 713\r"],["6DWJ_B_GLYB710","6dwj","GLY","DB00145(Glycine)","Homo sapiens","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","None",5,"GLY D 357;ASN D 358;ASP D 361;ARG B 371;ARG B 372","GLY B 710\r"],["6MN8_A_GLYA607","6mn8","GLY","DB00145(Glycine)","Onchocerca volvulus","UNCHARACTERIZED PROTEIN","PF00587(HGTP_anticodon);PF03129(tRNA-synt_2b)",4,"GLU A 379;ASP A 381;ARG A 383;TRP A 395","GLY A 607\r"]]