DRUG BINDING INTERFACES MAPPED TO 'DASATINIB'
DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2GQG_A_1N1A501 | 2gqg | 1N1 DB01254(Dasatinib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 | PF07714(Pkinase_Tyr) | 14 | LEU A 248TYR A 253ALA A 269LYS A 271GLU A 286MET A 290VAL A 299ILE A 313THR A 315PHE A 317MET A 318GLY A 321LEU A 370ALA A 380 | 1N1 A 501 |
2GQG_B_1N1B502 | 2gqg | 1N1 DB01254(Dasatinib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 | no annotation | 14 | LEU B 248VAL B 256ALA B 269LYS B 271GLU B 286MET B 290VAL B 299ILE B 313THR B 315MET B 318TYR B 320GLY B 321LEU B 370ALA B 380 | 1N1 B 502 |
2Y6O_A_1N1A1892 | 2y6o | 1N1 DB01254(Dasatinib) | Mus musculus | EPHRIN TYPE-ARECEPTOR 4 | PF07714(Pkinase_Tyr) | 13 | LYS A 625ILE A 627ALA A 651LYS A 653GLU A 670MET A 674ILE A 697THR A 699TYR A 701MET A 702GLY A 705LEU A 753SER A 763 | 1N1 A1892 |
2ZVA_A_1N1A513 | 2zva | 1N1 DB01254(Dasatinib) | Mus musculus | TYROSINE-PROTEINKINASE LYN | PF07714(Pkinase_Tyr) | 12 | LEU A 253ALA A 273LYS A 275GLU A 290MET A 294VAL A 303ILE A 317THR A 319MET A 322GLY A 325LEU A 374ALA A 384 | 1N1 A 513 |
3G5D_A_1N1A1 | 3g5d | 1N1 DB01254(Dasatinib) | Gallus gallus | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC | PF07714(Pkinase_Tyr) | 14 | LEU A 273VAL A 281ALA A 293LYS A 295GLU A 310MET A 314VAL A 323ILE A 336THR A 338TYR A 340MET A 341GLY A 344LEU A 393ALA A 403 | 1N1 A 1 |
3G5D_B_1N1B1 | 3g5d | 1N1 DB01254(Dasatinib) | Gallus gallus | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC | no annotation | 14 | LEU B 273VAL B 281ALA B 293LYS B 295GLU B 310MET B 314VAL B 323ILE B 336THR B 338TYR B 340MET B 341GLY B 344LEU B 393ALA B 403 | 1N1 B 1 |
3K54_A_1N1A1 | 3k54 | 1N1 DB01254(Dasatinib) | Homo sapiens | TYROSINE-PROTEINKINASE BTK | PF07714(Pkinase_Tyr) | 13 | LEU A 408ALA A 428LYS A 430GLU A 445MET A 449VAL A 458ILE A 472THR A 474TYR A 476MET A 477GLY A 480LEU A 528SER A 538 | 1N1 A 1 |
3LFA_A_1N1A361 | 3lfa | 1N1 DB01254(Dasatinib) | Homo sapiens | MITOGEN-ACTIVATEDPROTEIN KINASE 14 | PF00069(Pkinase) | 8 | VAL A 30ALA A 51LYS A 53GLU A 71LEU A 104THR A 106LEU A 108MET A 109 | 1N1 A 361 |
3OCT_A_1N1A663 | 3oct | 1N1 DB01254(Dasatinib) | Homo sapiens | TYROSINE-PROTEINKINASE BTK | PF07714(Pkinase_Tyr) | 17 | LEU A 408PHE A 413VAL A 416ALA A 428LYS A 430MET A 449VAL A 458ILE A 472THR A 474TYR A 476MET A 477ASN A 479GLY A 480GLU A 488LEU A 528SER A 538PHE A 540 | 1N1 A 663 |
3OHT_A_1N1A1000 | 3oht | 1N1 DB01254(Dasatinib) | Salmo salar | P38A | PF00069(Pkinase) | 15 | VAL A 31GLY A 32VAL A 39ALA A 52LYS A 54GLU A 72LEU A 76ILE A 85LEU A 105THR A 107LEU A 109ASN A 116LEU A 168ASP A 169PHE A 170 | 1N1 A1000 |
3OHT_A_1N1A2000 | 3oht | 1N1 DB01254(Dasatinib) | Salmo salar | P38A | PF00069(Pkinase)no annotation | 12 | ASP A 146ILE A 148ARG A 150ARG B 190ILE B 194TRP A 198MET A 199ASN A 202VAL A 205ILE B 230ALA B 256TYR B 259 | 1N1 A2000 |
3OHT_B_1N1B1000 | 3oht | 1N1 DB01254(Dasatinib) | Salmo salar | P38A | no annotation | 15 | GLY B 32VAL B 39ALA B 52LYS B 54GLU B 72LEU B 76ILE B 85LEU B 105THR B 107LEU B 109GLY B 111ASN B 116LEU B 168ASP B 169PHE B 170 | 1N1 B1000 |
3OHT_B_1N1B2000 | 3oht | 1N1 DB01254(Dasatinib) | Salmo salar | P38A | PF00069(Pkinase)no annotation | 10 | ILE B 148ARG B 150ARG A 190ILE A 194TRP B 198MET B 199ASN B 202VAL B 205ILE A 230TYR A 259 | 1N1 B2000 |
3QLG_A_1N1A601 | 3qlg | 1N1 DB01254(Dasatinib) | Gallus gallus | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC | PF07714(Pkinase_Tyr) | 14 | LEU A 273VAL A 281ALA A 293LYS A 295GLU A 310MET A 314VAL A 323ILE A 336THR A 338TYR A 340MET A 341GLY A 344LEU A 393ALA A 403 | 1N1 A 601 |
3QLG_B_1N1B601 | 3qlg | 1N1 DB01254(Dasatinib) | Gallus gallus | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC | no annotation | 16 | LEU B 273VAL B 281ALA B 293LYS B 295GLU B 310MET B 314VAL B 323ILE B 336THR B 338TYR B 340MET B 341LYS B 343GLY B 344LEU B 393ALA B 403ASP B 404 | 1N1 B 601 |
3SXR_A_1N1A1 | 3sxr | 1N1 DB01254(Dasatinib) | Homo sapiens | CYTOPLASMICTYROSINE-PROTEINKINASE BMX | PF07714(Pkinase_Tyr) | 14 | LEU A 423VAL A 431ALA A 443LYS A 445MET A 464VAL A 473ILE A 487THR A 489TYR A 491ILE A 492GLY A 495LEU A 543SER A 553PHE A 555 | 1N1 A 1 |
3SXR_B_1N1B2 | 3sxr | 1N1 DB01254(Dasatinib) | Homo sapiens | CYTOPLASMICTYROSINE-PROTEINKINASE BMX | no annotation | 13 | LEU B 423VAL B 431ALA B 443LYS B 445MET B 464VAL B 473THR B 489TYR B 491ILE B 492GLY B 495LEU B 543SER B 553PHE B 555 | 1N1 B 2 |
4QMS_A_1N1A401 | 4qms | 1N1 DB01254(Dasatinib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE 24 | PF00069(Pkinase) | 11 | ILE A 30LYS A 32ALA A 51LYS A 53GLU A 70ILE A 97MET A 99TYR A 101LEU A 102LEU A 151ASP A 162 | 1N1 A 401 |
4XEY_A_1N1A601 | 4xey | 1N1 DB01254(Dasatinib) | Homo sapiens | TYROSINE-PROTEINKINASE ABL1 | PF07714(Pkinase_Tyr) | 15 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334PHE A 336MET A 337GLY A 340LEU A 389ALA A 399ASP A 400PHE A 401 | 1N1 A 601 |
4XEY_B_1N1B601 | 4xey | 1N1 DB01254(Dasatinib) | Homo sapiens | TYROSINE-PROTEINKINASE ABL1 | no annotation | 15 | LEU B 267VAL B 275ALA B 288LYS B 290MET B 309VAL B 318ILE B 332THR B 334PHE B 336MET B 337GLY B 340LEU B 389ALA B 399ASP B 400PHE B 401 | 1N1 B 601 |
4XLI_A_1N1A601 | 4xli | 1N1 DB01254(Dasatinib) | Mus musculus | NON-SPECIFICPROTEIN-TYROSINEKINASE | PF07714(Pkinase_Tyr) | 12 | LEU A 294ALA A 315LYS A 317GLU A 332MET A 336VAL A 345THR A 361TYR A 363MET A 364GLY A 367LEU A 416ALA A 426 | 1N1 A 601 |
4XLI_B_1N1B600 | 4xli | 1N1 DB01254(Dasatinib) | Mus musculus | NON-SPECIFICPROTEIN-TYROSINEKINASE | no annotation | 13 | LEU B 294ALA B 315LYS B 317GLU B 332MET B 336VAL B 345ILE B 359THR B 361TYR B 363MET B 364GLY B 367LEU B 416ALA B 426 | 1N1 B 600 |
5BVW_A_1N1A1009 | 5bvw | 1N1 DB01254(Dasatinib) | Homo sapiens | EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1 | PF07714(Pkinase_Tyr) | 14 | LEU A 616VAL A 624ALA A 653LYS A 655GLU A 672MET A 676ILE A 685MET A 699THR A 701TYR A 703MET A 704GLY A 707LEU A 773ALA A 783 | 1N1 A1009 |
5H2U_A_1N1A501 | 5h2u | 1N1 DB01254(Dasatinib) | Homo sapiens | PROTEIN-TYROSINEKINASE 6 | PF07714(Pkinase_Tyr) | 15 | ARG A 195LEU A 197VAL A 205ALA A 217LYS A 219LEU A 248ILE A 262THR A 264LEU A 266MET A 267GLY A 270GLU A 274LEU A 319GLY A 329ASP A 330 | 1N1 A 501 |
5H2U_B_1N1B501 | 5h2u | 1N1 DB01254(Dasatinib) | Homo sapiens | PROTEIN-TYROSINEKINASE 6 | no annotation | 13 | LEU B 197VAL B 205ALA B 217LYS B 219LEU B 248ILE B 262THR B 264LEU B 266MET B 267GLY B 270LEU B 319GLY B 329ASP B 330 | 1N1 B 501 |
5H2U_C_1N1C501 | 5h2u | 1N1 DB01254(Dasatinib) | Homo sapiens | PROTEIN-TYROSINEKINASE 6 | no annotation | 13 | ARG C 195LEU C 197ALA C 217LYS C 219LEU C 248ILE C 262THR C 264MET C 267GLY C 270GLU C 274LEU C 319GLY C 329ASP C 330 | 1N1 C 501 |
5H2U_D_1N1D504 | 5h2u | 1N1 DB01254(Dasatinib) | Homo sapiens | PROTEIN-TYROSINEKINASE 6 | no annotation | 13 | LEU D 197VAL D 205ALA D 217LYS D 219LEU D 248ILE D 262THR D 264LEU D 266MET D 267GLY D 270LEU D 319GLY D 329ASP D 330 | 1N1 D 504 |
5I9Y_A_1N1A1001 | 5i9y | 1N1 DB01254(Dasatinib) | Homo sapiens | EPHRIN TYPE-ARECEPTOR 2 | PF07714(Pkinase_Tyr) | 15 | ILE A 619ALA A 644LYS A 646GLU A 663MET A 667ILE A 676ILE A 690THR A 692TYR A 694MET A 695GLY A 698LYS A 702GLU A 706LEU A 746SER A 756 | 1N1 A1001 |
5OWR_A_1N1A401 | 5owr | 1N1 DB01254(Dasatinib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE 10 | PF00069(Pkinase) | 8 | ALA A 63LYS A 65GLU A 81ILE A 110CYS A 113LEU A 164ASP A 175VAL A 314 | 1N1 A 401 |
5VCV_A_1N1A404 | 5vcv | 1N1 DB01254(Dasatinib) | Homo sapiens | MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE | PF00069(Pkinase) | 17 | LEU A 116VAL A 124ALA A 137LYS A 139GLU A 157HIS A 161VAL A 171LEU A 185THR A 187LEU A 189CYS A 190GLY A 191PRO A 192GLN A 196PHE A 240GLY A 250ASP A 251 | 1N1 A 404 |
6BSD_A_1N1A901 | 6bsd | 1N1 DB01254(Dasatinib) | Homo sapiens | EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1 | PF00754(F5_F8_type_C) | 14 | VAL A 587ALA A 616LYS A 618GLU A 635MET A 639ILE A 648MET A 662THR A 664TYR A 666MET A 667GLY A 670LEU A 736ALA A 746ASP A 747 | 1N1 A 901 |
6FNM_A_1N1A1001 | 6fnm | 1N1 DB01254(Dasatinib) | - | - | no annotation | 13 | ILE A 621VAL A 629ALA A 645LYS A 647GLU A 664MET A 668ILE A 691THR A 693MET A 696ASN A 698GLY A 699LEU A 747SER A 757 | 1N1 A1001 |