DRUG BINDING INTERFACES MAPPED TO 'DABRAFENIB'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
4XV2_A_P06A801	4xv2	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	PF07714 (Pkinase_Tyr)	16	GLY A 466 PHE A 468 VAL A 471 ALA A 481 LYS A 483 LEU A 505 LEU A 514 PHE A 516 ILE A 527 THR A 529 TRP A 531 CYS A 532 PHE A 583 GLY A 593 ASP A 594 PHE A 595	P06 A 801
4XV2_B_P06B801	4xv2	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	no annotation	16	GLY B 466 PHE B 468 VAL B 471 ALA B 481 LYS B 483 LEU B 505 LEU B 514 PHE B 516 ILE B 527 THR B 529 TRP B 531 CYS B 532 PHE B 583 GLY B 593 ASP B 594 PHE B 595	P06 B 801
5CSW_A_P06A801	5csw	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	PF07714 (Pkinase_Tyr)	15	PHE A 468 VAL A 471 ALA A 481 LYS A 483 LEU A 505 LEU A 514 PHE A 516 ILE A 527 THR A 529 TRP A 531 CYS A 532 PHE A 583 GLY A 593 ASP A 594 PHE A 595	P06 A 801
5CSW_B_P06B801	5csw	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	no annotation	15	PHE B 468 VAL B 471 ALA B 481 LYS B 483 LEU B 505 LEU B 514 PHE B 516 ILE B 527 THR B 529 TRP B 531 CYS B 532 PHE B 583 GLY B 593 ASP B 594 PHE B 595	P06 B 801
5HIE_A_P06A801	5hie	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	PF07714 (Pkinase_Tyr)	19	ILE A 463 GLY A 464 GLY A 466 PHE A 468 VAL A 471 ALA A 481 LYS A 483 PHE A 498 LEU A 505 LEU A 514 PHE A 516 ILE A 527 THR A 529 TRP A 531 CYS A 532 PHE A 583 GLY A 593 ASP A 594 PHE A 595	P06 A 801
5HIE_B_P06B801	5hie	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	no annotation	19	ILE B 463 GLY B 464 GLY B 466 PHE B 468 VAL B 471 ALA B 481 LYS B 483 PHE B 498 LEU B 505 LEU B 514 PHE B 516 ILE B 527 THR B 529 TRP B 531 CYS B 532 PHE B 583 GLY B 593 ASP B 594 PHE B 595	P06 B 801
5HIE_C_P06C801	5hie	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	no annotation	19	ILE C 463 GLY C 464 GLY C 466 PHE C 468 VAL C 471 ALA C 481 LYS C 483 VAL C 504 LEU C 514 PHE C 516 ILE C 527 THR C 529 TRP C 531 CYS C 532 ASN C 580 PHE C 583 GLY C 593 ASP C 594 PHE C 595	P06 C 801
5HIE_D_P06D801	5hie	P06 DB08912 (Dabrafenib)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE B-RAF	no annotation	20	ILE D 463 GLY D 464 GLY D 466 PHE D 468 VAL D 471 ALA D 481 LYS D 483 PHE D 498 VAL D 504 LEU D 514 PHE D 516 ILE D 527 THR D 529 TRP D 531 CYS D 532 ASN D 580 PHE D 583 GLY D 593 ASP D 594 PHE D 595	P06 D 801

[["4XV2_A_P06A801","4xv2","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","PF07714(Pkinase_Tyr)",16,"GLY A 466;PHE A 468;VAL A 471;ALA A 481;LYS A 483;LEU A 505;LEU A 514;PHE A 516;ILE A 527;THR A 529;TRP A 531;CYS A 532;PHE A 583;GLY A 593;ASP A 594;PHE A 595","P06 A 801\r"],["4XV2_B_P06B801","4xv2","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","no annotation",16,"GLY B 466;PHE B 468;VAL B 471;ALA B 481;LYS B 483;LEU B 505;LEU B 514;PHE B 516;ILE B 527;THR B 529;TRP B 531;CYS B 532;PHE B 583;GLY B 593;ASP B 594;PHE B 595","P06 B 801\r"],["5CSW_A_P06A801","5csw","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","PF07714(Pkinase_Tyr)",15,"PHE A 468;VAL A 471;ALA A 481;LYS A 483;LEU A 505;LEU A 514;PHE A 516;ILE A 527;THR A 529;TRP A 531;CYS A 532;PHE A 583;GLY A 593;ASP A 594;PHE A 595","P06 A 801\r"],["5CSW_B_P06B801","5csw","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","no annotation",15,"PHE B 468;VAL B 471;ALA B 481;LYS B 483;LEU B 505;LEU B 514;PHE B 516;ILE B 527;THR B 529;TRP B 531;CYS B 532;PHE B 583;GLY B 593;ASP B 594;PHE B 595","P06 B 801\r"],["5HIE_A_P06A801","5hie","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","PF07714(Pkinase_Tyr)",19,"ILE A 463;GLY A 464;GLY A 466;PHE A 468;VAL A 471;ALA A 481;LYS A 483;PHE A 498;LEU A 505;LEU A 514;PHE A 516;ILE A 527;THR A 529;TRP A 531;CYS A 532;PHE A 583;GLY A 593;ASP A 594;PHE A 595","P06 A 801\r"],["5HIE_B_P06B801","5hie","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","no annotation",19,"ILE B 463;GLY B 464;GLY B 466;PHE B 468;VAL B 471;ALA B 481;LYS B 483;PHE B 498;LEU B 505;LEU B 514;PHE B 516;ILE B 527;THR B 529;TRP B 531;CYS B 532;PHE B 583;GLY B 593;ASP B 594;PHE B 595","P06 B 801\r"],["5HIE_C_P06C801","5hie","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","no annotation",19,"ILE C 463;GLY C 464;GLY C 466;PHE C 468;VAL C 471;ALA C 481;LYS C 483;VAL C 504;LEU C 514;PHE C 516;ILE C 527;THR C 529;TRP C 531;CYS C 532;ASN C 580;PHE C 583;GLY C 593;ASP C 594;PHE C 595","P06 C 801\r"],["5HIE_D_P06D801","5hie","P06","DB08912(Dabrafenib)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","no annotation",20,"ILE D 463;GLY D 464;GLY D 466;PHE D 468;VAL D 471;ALA D 481;LYS D 483;PHE D 498;VAL D 504;LEU D 514;PHE D 516;ILE D 527;THR D 529;TRP D 531;CYS D 532;ASN D 580;PHE D 583;GLY D 593;ASP D 594;PHE D 595","P06 D 801\r"]]