DRUG BINDING INTERFACES MAPPED TO 'CRIZOTINIB'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
2WGJ_A_VGHA2346	2wgj	VGH DB08865 (Crizotinib)	Homo sapiens	HEPATOCYTE GROWTH FACTOR RECEPTOR	PF07714 (Pkinase_Tyr)	13	GLY A1085 VAL A1092 ALA A1108 LEU A1140 LEU A1157 TYR A1159 MET A1160 GLY A1163 ASN A1209 MET A1211 ALA A1221 ASP A1222 TYR A1230	VGH A2346
2XP2_A_VGHA9000	2xp2	VGH DB08865 (Crizotinib)	Homo sapiens	TYROSINE-PROTEIN KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	9	LEU A1122 VAL A1130 ALA A1148 LEU A1196 MET A1199 GLY A1202 LEU A1256 GLY A1269 ASP A1270	VGH A9000
2YFX_A_VGHA9000	2yfx	VGH DB08865 (Crizotinib)	Homo sapiens	TYROSINE-PROTEIN KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	8	LEU A1122 ALA A1148 MET A1196 MET A1199 GLY A1202 LEU A1256 GLY A1269 ASP A1270	VGH A9000
3ZBF_A_VGHA3000	3zbf	VGH DB08865 (Crizotinib)	Homo sapiens	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS	PF07714 (Pkinase_Tyr)	12	LEU A1951 ALA A1978 LEU A2010 LEU A2026 LEU A2028 MET A2029 GLY A2032 ASP A2033 THR A2036 LEU A2086 GLY A2101 ASP A2102	VGH A3000
4ANQ_A_VGHA9000	4anq	VGH DB08865 (Crizotinib)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	9	LEU A1122 VAL A1130 ALA A1148 LEU A1196 MET A1199 GLY A1202 LEU A1256 ALA A1269 ASP A1270	VGH A9000
4ANS_A_VGHA9000	4ans	VGH DB08865 (Crizotinib)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	9	LEU A1122 VAL A1130 ALA A1148 MET A1196 MET A1199 GLY A1202 LEU A1256 ALA A1269 ASP A1270	VGH A9000
4C9W_A_VGHA1158	4c9w	VGH DB08865 (Crizotinib)	Homo sapiens	7,8-DIHYDRO-8-OXOGUA NINE TRIPHOSPHATASE	PF00293 (NUDIX)	12	TYR A 7 LEU A 9 ASN A 33 PHE A 72 PHE A 74 MET A 81 VAL A 83 TRP A 117 ASP A 119 ASP A 120 PHE A 139 GLN A 142	VGH A1158
5AAA_A_VGHA9000	5aaa	VGH DB08865 (Crizotinib)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	9	LEU A1122 VAL A1130 ALA A1148 LEU A1196 MET A1199 GLY A1202 LEU A1256 GLY A1269 ASP A1270	VGH A9000
5AAB_A_VGHA9000	5aab	VGH DB08865 (Crizotinib)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	10	LEU A1122 VAL A1130 ALA A1148 LYS A1150 LEU A1196 MET A1199 GLY A1202 LEU A1256 GLY A1269 ASP A1270	VGH A9000
5AAC_A_VGHA9000	5aac	VGH DB08865 (Crizotinib)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PF07714 (Pkinase_Tyr)	10	LEU A1122 VAL A1130 ALA A1148 LYS A1150 LEU A1196 MET A1199 GLY A1202 LEU A1256 GLY A1269 ASP A1270	VGH A9000

[["2WGJ_A_VGHA2346","2wgj","VGH","DB08865(Crizotinib)","Homo sapiens","HEPATOCYTE GROWTH FACTOR RECEPTOR","PF07714(Pkinase_Tyr)",13,"GLY A1085;VAL A1092;ALA A1108;LEU A1140;LEU A1157;TYR A1159;MET A1160;GLY A1163;ASN A1209;MET A1211;ALA A1221;ASP A1222;TYR A1230","VGH A2346\r"],["2XP2_A_VGHA9000","2xp2","VGH","DB08865(Crizotinib)","Homo sapiens","TYROSINE-PROTEIN KINASE RECEPTOR","PF07714(Pkinase_Tyr)",9,"LEU A1122;VAL A1130;ALA A1148;LEU A1196;MET A1199;GLY A1202;LEU A1256;GLY A1269;ASP A1270","VGH A9000\r"],["2YFX_A_VGHA9000","2yfx","VGH","DB08865(Crizotinib)","Homo sapiens","TYROSINE-PROTEIN KINASE RECEPTOR","PF07714(Pkinase_Tyr)",8,"LEU A1122;ALA A1148;MET A1196;MET A1199;GLY A1202;LEU A1256;GLY A1269;ASP A1270","VGH A9000\r"],["3ZBF_A_VGHA3000","3zbf","VGH","DB08865(Crizotinib)","Homo sapiens","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS","PF07714(Pkinase_Tyr)",12,"LEU A1951;ALA A1978;LEU A2010;LEU A2026;LEU A2028;MET A2029;GLY A2032;ASP A2033;THR A2036;LEU A2086;GLY A2101;ASP A2102","VGH A3000\r"],["4ANQ_A_VGHA9000","4anq","VGH","DB08865(Crizotinib)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PF07714(Pkinase_Tyr)",9,"LEU A1122;VAL A1130;ALA A1148;LEU A1196;MET A1199;GLY A1202;LEU A1256;ALA A1269;ASP A1270","VGH A9000\r"],["4ANS_A_VGHA9000","4ans","VGH","DB08865(Crizotinib)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PF07714(Pkinase_Tyr)",9,"LEU A1122;VAL A1130;ALA A1148;MET A1196;MET A1199;GLY A1202;LEU A1256;ALA A1269;ASP A1270","VGH A9000\r"],["4C9W_A_VGHA1158","4c9w","VGH","DB08865(Crizotinib)","Homo sapiens","7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE","PF00293(NUDIX)",12,"TYR A   7;LEU A   9;ASN A  33;PHE A  72;PHE A  74;MET A  81;VAL A  83;TRP A 117;ASP A 119;ASP A 120;PHE A 139;GLN A 142","VGH A1158\r"],["5AAA_A_VGHA9000","5aaa","VGH","DB08865(Crizotinib)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PF07714(Pkinase_Tyr)",9,"LEU A1122;VAL A1130;ALA A1148;LEU A1196;MET A1199;GLY A1202;LEU A1256;GLY A1269;ASP A1270","VGH A9000\r"],["5AAB_A_VGHA9000","5aab","VGH","DB08865(Crizotinib)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PF07714(Pkinase_Tyr)",10,"LEU A1122;VAL A1130;ALA A1148;LYS A1150;LEU A1196;MET A1199;GLY A1202;LEU A1256;GLY A1269;ASP A1270","VGH A9000\r"],["5AAC_A_VGHA9000","5aac","VGH","DB08865(Crizotinib)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PF07714(Pkinase_Tyr)",10,"LEU A1122;VAL A1130;ALA A1148;LYS A1150;LEU A1196;MET A1199;GLY A1202;LEU A1256;GLY A1269;ASP A1270","VGH A9000\r"]]