SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r7f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 7 ARG A 280
ASP A 290
ASP A 292
TYR A 285
 None
MG  A 506 (-2.1A)
MG  A 506 (-3.2A)
None
 1.40A 1ceaB-4r7fA:
undetectable		 1ceaB-4r7fA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 ARG A 280
ASP A 209
TYR A 395
GLU A 385
 None
 1.08A 1rjdA-4r7fA:
undetectable		 1rjdA-4r7fA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 ARG A 280
ASP A 209
TYR A 395
GLU A 385
 None
 1.08A 1rjdB-4r7fA:
undetectable		 1rjdB-4r7fA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 ARG A 280
ASP A 209
TYR A 395
GLU A 385
 None
 1.08A 1rjdC-4r7fA:
undetectable		 1rjdC-4r7fA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 THR A 415
GLY A 413
ILE A 397
VAL A 399
 None
 0.94A 1rxcB-4r7fA:
undetectable		 1rxcB-4r7fA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 THR A 415
GLY A 413
ILE A 397
VAL A 399
 None
 0.95A 1rxcE-4r7fA:
undetectable		 1rxcE-4r7fA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 THR A 415
GLY A 413
ILE A 397
VAL A 399
 None
 0.92A 1rxcI-4r7fA:
undetectable		 1rxcI-4r7fA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 THR A 415
GLY A 413
ILE A 397
VAL A 399
 None
 0.93A 1rxcK-4r7fA:
undetectable		 1rxcK-4r7fA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3V_A_TOPA1169_1
(DIHYDROFOLATE
REDUCTASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 VAL A  30
ALA A 154
ILE A  62
ILE A  35
THR A  28
 None
 1.11A 2w3vA-4r7fA:
undetectable		 2w3vA-4r7fA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA315_0
(UNCHARACTERIZED
PROTEIN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 LYS A  41
ILE A  62
LYS A 361
PHE A 295
ILE A  35
 None
 1.45A 3ijdA-4r7fA:
undetectable		 3ijdA-4r7fA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 VAL A  30
ALA A 154
ILE A  62
ILE A  35
THR A  28
 None
 1.05A 3qfxA-4r7fA:
undetectable		 3qfxA-4r7fA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 VAL A  30
ALA A 154
ILE A  62
ILE A  35
THR A  28
 None
 1.05A 3qfxB-4r7fA:
undetectable		 3qfxB-4r7fA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 TYR A 395
ILE A 397
VAL A 184
TYR A 231
ILE A 204
 None
None
None
None
CL  A 504 (-4.8A)
 1.18A 3vrjA-4r7fA:
2.5
3vrjC-4r7fA:
undetectable		 3vrjA-4r7fA:
20.64
3vrjC-4r7fA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		3 / 3 ASN A 210
GLU A 333
ARG A 294
 TRS  A 503 (-3.9A)
None
None
 1.09A 3wxoA-4r7fA:
undetectable		 3wxoA-4r7fA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 THR A 415
GLY A 413
ILE A 397
VAL A 399
 None
 0.96A 4e1vD-4r7fA:
undetectable		 4e1vD-4r7fA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 ASP A 290
ASP A 292
GLU A 394
ASN A 337
 MG  A 506 (-2.1A)
MG  A 506 (-3.2A)
None
None
 1.40A 4ntxA-4r7fA:
undetectable
4ntxC-4r7fA:
undetectable		 4ntxA-4r7fA:
21.27
4ntxC-4r7fA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 THR A 115
THR A 114
HIS A 315
LEU A 359
 None
 1.04A 4pgfA-4r7fA:
undetectable		 4pgfA-4r7fA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.35A 4qvyV-4r7fA:
undetectable
4qvyb-4r7fA:
undetectable		 4qvyV-4r7fA:
17.36
4qvyb-4r7fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.35A 4qvyH-4r7fA:
undetectable
4qvyN-4r7fA:
undetectable		 4qvyH-4r7fA:
17.36
4qvyN-4r7fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.33A 5l5fV-4r7fA:
undetectable
5l5fb-4r7fA:
undetectable		 5l5fV-4r7fA:
17.36
5l5fb-4r7fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.33A 5l5fH-4r7fA:
undetectable
5l5fN-4r7fA:
undetectable		 5l5fH-4r7fA:
17.36
5l5fN-4r7fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.33A 5l5zV-4r7fA:
undetectable
5l5zb-4r7fA:
undetectable		 5l5zV-4r7fA:
17.36
5l5zb-4r7fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.33A 5l5zH-4r7fA:
undetectable
5l5zN-4r7fA:
undetectable		 5l5zH-4r7fA:
17.36
5l5zN-4r7fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 ASP A  29
ASP A  65
ASN A  63
ASN A 336
 None
 0.99A 5l6eA-4r7fA:
undetectable		 5l6eA-4r7fA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.34A 5lf3b-4r7fA:
undetectable		 5lf3b-4r7fA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 THR A 113
THR A 114
THR A 115
SER A 252
ALA A 309
 None
 1.34A 5lf3N-4r7fA:
undetectable		 5lf3N-4r7fA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 9 LEU A 124
PHE A 131
VAL A  78
HIS A  80
ILE A 139
 None
 1.17A 5om2A-4r7fA:
undetectable
5om2B-4r7fA:
undetectable		 5om2A-4r7fA:
12.75
5om2B-4r7fA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 7 TYR A 369
ASP A 277
THR A 317
LEU A 274
 None
 1.12A 5ov9A-4r7fA:
undetectable		 5ov9A-4r7fA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 GLY A 332
GLN A 392
ASP A 209
ASP A 213
 None
MG  A 506 (-3.7A)
None
None
 0.75A 5vlmB-4r7fA:
undetectable		 5vlmB-4r7fA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 GLY A 332
GLN A 392
ASP A 209
ASP A 213
 None
MG  A 506 (-3.7A)
None
None
 0.83A 5vlmH-4r7fA:
undetectable		 5vlmH-4r7fA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 7 ASP A 292
ASP A 209
ARG A 294
GLN A 392
 MG  A 506 (-3.2A)
None
None
MG  A 506 (-3.7A)
 1.41A 6g31A-4r7fA:
undetectable		 6g31A-4r7fA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 7 ASP A 292
ASP A 209
ARG A 294
GLN A 392
 MG  A 506 (-3.2A)
None
None
MG  A 506 (-3.7A)
 1.36A 6g31D-4r7fA:
undetectable		 6g31D-4r7fA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 4 ASP A 292
ASP A 209
ARG A 294
GLN A 392
 MG  A 506 (-3.2A)
None
None
MG  A 506 (-3.7A)
 1.41A 6g31K-4r7fA:
undetectable		 6g31K-4r7fA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 6 ASP A 292
ASP A 209
ARG A 294
GLN A 392
 MG  A 506 (-3.2A)
None
None
MG  A 506 (-3.7A)
 1.34A 6g31L-4r7fA:
undetectable		 6g31L-4r7fA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 TYR A 245
ASP A 277
THR A 381
GLY A 386
ASP A 281
 None
 1.35A 6mb5A-4r7fA:
undetectable		 6mb5A-4r7fA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 10 TYR A 245
ASP A 277
THR A 381
GLY A 386
ASP A 281
 None
 1.36A 6mb9A-4r7fA:
undetectable		 6mb9A-4r7fA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 10 TYR A 245
ASP A 277
THR A 381
GLY A 386
ASP A 281
 None
 1.37A 6mb9B-4r7fA:
undetectable		 6mb9B-4r7fA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 4r7f UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 10 TYR A 245
ASP A 277
THR A 381
GLY A 386
ASP A 281
 None
 1.36A 6mb9C-4r7fA:
undetectable		 6mb9C-4r7fA:
10.08