SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZZX'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3L2U_A_ELVA397_1 (INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	5 / 5	ASP A 128 ASP A 185 TYR A 212 PRO A 214 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) MG A 397 ( 1.8A)	0.48A	3l2uA-3oynA: 43.4	3l2uA-3oynA: 99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3L2V_A_RLTA397_1 (INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	7 / 7	ASP A 128 ASP A 185 GLN A 186 TYR A 212 PRO A 214 GLN A 215 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) None ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) ZZX A 398 (-3.9A) MG A 397 ( 1.8A)	0.78A	3l2vA-3oynA: 43.1	3l2vA-3oynA: 99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3L2W_A_ELVA397_1 (INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	5 / 5	ASP A 128 ASP A 185 TYR A 212 PRO A 214 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) MG A 397 ( 1.8A)	0.46A	3l2wA-3oynA: 43.4	3l2wA-3oynA: 99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OYA_A_RLTA398_1 (PFV INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	8 / 8	ASP A 128 ASP A 185 GLN A 186 PRO A 211 TYR A 212 PRO A 214 GLN A 215 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) None None ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) ZZX A 398 (-3.9A) MG A 397 ( 1.8A)	0.46A	3oyaA-3oynA: 44.9	3oyaA-3oynA: 99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S3M_A_DLUA398_1 (PFV INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	7 / 8	ASP A 128 ASP A 185 GLY A 187 TYR A 212 PRO A 214 GLN A 215 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) ZZX A 398 ( 3.7A) ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) ZZX A 398 (-3.9A) MG A 397 ( 1.8A)	0.32A	3s3mA-3oynA: 45.1	3s3mA-3oynA: 99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S3N_A_DLUA398_1 (PFV INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	7 / 8	ASP A 128 ASP A 185 GLY A 187 TYR A 212 PRO A 214 GLN A 215 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) ZZX A 398 ( 3.7A) ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) ZZX A 398 (-3.9A) MG A 397 ( 1.8A)	0.33A	3s3nA-3oynA: 44.8	3s3nA-3oynA: 99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S3O_A_DLUA399_1 (PFV INTEGRASE)	3oyn	PFV INTEGRASE (Simian foamy virus)	6 / 7	ASP A 128 ASP A 185 TYR A 212 PRO A 214 GLN A 215 GLU A 221	MG A 396 (-2.6A) MG A 396 ( 2.7A) ZZX A 398 ( 4.0A) ZZX A 398 (-4.1A) ZZX A 398 (-3.9A) MG A 397 ( 1.8A)	0.32A	3s3oA-3oynA: 45.4	3s3oA-3oynA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DMG_A_SAMA401_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493)	3oyn	PFV INTEGRASE (Simian foamy virus)	5 / 12	GLN A 215 TYR A 212 ASP A 367 GLU A 325 ALA A 328	ZZX A 398 (-3.9A) ZZX A 398 ( 4.0A) None None None	1.27A	4dmgA-3oynA: undetectable	4dmgA-3oynA: 21.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3L2U_A_ELVA397_1","INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",5,"ASP A 128;ASP A 185;TYR A 212;PRO A 214;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A); MG A 397 ( 1.8A)","0.48A","3l2uA-3oynA:43.4",null],["3L2V_A_RLTA397_1","INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",7,"ASP A 128;ASP A 185;GLN A 186;TYR A 212;PRO A 214;GLN A 215;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);None;ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A);ZZX A 398 (-3.9A); MG A 397 ( 1.8A)","0.78A","3l2vA-3oynA:43.1","3l2uA-3oynA:99.75"],["3L2W_A_ELVA397_1","INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",5,"ASP A 128;ASP A 185;TYR A 212;PRO A 214;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A); MG A 397 ( 1.8A)","0.46A","3l2wA-3oynA:43.4","3l2vA-3oynA:99.75"],["3OYA_A_RLTA398_1","PFV INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",8,"ASP A 128;ASP A 185;GLN A 186;PRO A 211;TYR A 212;PRO A 214;GLN A 215;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);None;None;ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A);ZZX A 398 (-3.9A); MG A 397 ( 1.8A)","0.46A","3oyaA-3oynA:44.9","3l2wA-3oynA:99.75"],["3S3M_A_DLUA398_1","PFV INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",7,"ASP A 128;ASP A 185;GLY A 187;TYR A 212;PRO A 214;GLN A 215;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);ZZX A 398 ( 3.7A);ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A);ZZX A 398 (-3.9A); MG A 397 ( 1.8A)","0.32A","3s3mA-3oynA:45.1","3oyaA-3oynA:99.75"],["3S3N_A_DLUA398_1","PFV INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",7,"ASP A 128;ASP A 185;GLY A 187;TYR A 212;PRO A 214;GLN A 215;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);ZZX A 398 ( 3.7A);ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A);ZZX A 398 (-3.9A); MG A 397 ( 1.8A)","0.33A","3s3nA-3oynA:44.8","3s3mA-3oynA:99.75"],["3S3O_A_DLUA399_1","PFV INTEGRASE","3oyn","PFV INTEGRASE","Simian foamy virus",6,"ASP A 128;ASP A 185;TYR A 212;PRO A 214;GLN A 215;GLU A 221"," MG A 396 (-2.6A); MG A 396 ( 2.7A);ZZX A 398 ( 4.0A);ZZX A 398 (-4.1A);ZZX A 398 (-3.9A); MG A 397 ( 1.8A)","0.32A","3s3oA-3oynA:45.4","3s3nA-3oynA:99.49"],["4DMG_A_SAMA401_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493","3oyn","PFV INTEGRASE","Simian foamy virus",5,"GLN A 215;TYR A 212;ASP A 367;GLU A 325;ALA A 328","ZZX A 398 (-3.9A);ZZX A 398 ( 4.0A);None;None;None","1.27A","4dmgA-3oynA:undetectable","3s3oA-3oynA:100.00"]]