SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZKD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 10 TYR A 447
SER A 356
PHE A 543
LEU A 473
VAL A 479
 ZKD  A1569 (-4.0A)
None
None
None
None
 1.40A 1q23E-2xgoA:
undetectable		 1q23E-2xgoA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 11 TYR A 447
SER A 356
PHE A 543
LEU A 473
VAL A 479
 ZKD  A1569 (-4.0A)
None
None
None
None
 1.41A 1q23J-2xgoA:
undetectable		 1q23J-2xgoA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 PHE A 457
CYH A 382
TYR A 447
TYR A 451
 None
None
ZKD  A1569 (-4.0A)
None
 1.24A 1xqlA-2xgoA:
2.5
1xqlB-2xgoA:
2.2		 1xqlA-2xgoA:
23.16
1xqlB-2xgoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 TYR A 447
TYR A 451
PHE A 457
CYH A 382
 ZKD  A1569 (-4.0A)
None
None
None
 1.22A 1xqlA-2xgoA:
2.5
1xqlB-2xgoA:
2.2		 1xqlA-2xgoA:
23.16
1xqlB-2xgoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 LEU A 222
GLY A 214
GLY A 216
GLY A 250
PRO A 445
 ZKD  A1569 (-4.4A)
None
None
None
None
 1.17A 1y4lA-2xgoA:
undetectable		 1y4lA-2xgoA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2xgo XCOGT
(Xanthomonas
campestris) 		3 / 3 TYR A 447
ALA A 472
TYR A 451
 ZKD  A1569 (-4.0A)
None
None
 0.83A 5uunB-2xgoA:
undetectable		 5uunB-2xgoA:
19.02