SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZIP'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEO_B_LLTB261_1 (DEOXYCYTIDINE KINASE)	3t4j	HISTIDINE KINASE 4 (Arabidopsis thaliana)	4 / 7	VAL A 241 LEU A 251 GLN A 181 PHE A 184	None ZIP A 400 (-4.7A) None None	1.04A	3qeoB-3t4jA: undetectable	3qeoB-3t4jA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3O_B_T1CB405_1 (TETX2 PROTEIN)	3t4j	HISTIDINE KINASE 4 (Arabidopsis thaliana)	5 / 12	PHE A 153 ASN A 158 GLY A 379 ALA A 322 GLY A 321	None None None ZIP A 400 (-3.5A) None	1.24A	3v3oB-3t4jA: undetectable	3v3oB-3t4jA: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A6N_A_T1CA392_1 (TETX2 PROTEIN)	3t4j	HISTIDINE KINASE 4 (Arabidopsis thaliana)	5 / 11	PHE A 153 ASN A 158 GLY A 379 ALA A 322 GLY A 321	None None None ZIP A 400 (-3.5A) None	1.15A	4a6nA-3t4jA: undetectable	4a6nA-3t4jA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z7F_C_FOLC201_0 (FOLATE ECF TRANSPORTER)	3t4j	HISTIDINE KINASE 4 (Arabidopsis thaliana)	5 / 12	ALA A 204 PHE A 184 THR A 188 LEU A 163 ARG A 195	ZIP A 400 ( 4.1A) None None None None	1.18A	4z7fC-3t4jA: undetectable	4z7fC-3t4jA: 21.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3QEO_B_LLTB261_1","DEOXYCYTIDINE KINASE","3t4j","HISTIDINE KINASE 4","Arabidopsis thaliana",4,"VAL A 241;LEU A 251;GLN A 181;PHE A 184","None;ZIP A 400 (-4.7A);None;None","1.04A","3qeoB-3t4jA:undetectable",null],["3V3O_B_T1CB405_1","TETX2 PROTEIN","3t4j","HISTIDINE KINASE 4","Arabidopsis thaliana",5,"PHE A 153;ASN A 158;GLY A 379;ALA A 322;GLY A 321","None;None;None;ZIP A 400 (-3.5A);None","1.24A","3v3oB-3t4jA:undetectable","3qeoB-3t4jA:20.61"],["4A6N_A_T1CA392_1","TETX2 PROTEIN","3t4j","HISTIDINE KINASE 4","Arabidopsis thaliana",5,"PHE A 153;ASN A 158;GLY A 379;ALA A 322;GLY A 321","None;None;None;ZIP A 400 (-3.5A);None","1.15A","4a6nA-3t4jA:undetectable","3v3oB-3t4jA:22.62"],["4Z7F_C_FOLC201_0","FOLATE ECF TRANSPORTER","3t4j","HISTIDINE KINASE 4","Arabidopsis thaliana",5,"ALA A 204;PHE A 184;THR A 188;LEU A 163;ARG A 195","ZIP A 400 ( 4.1A);None;None;None;None","1.18A","4z7fC-3t4jA:undetectable","4a6nA-3t4jA:21.41"]]