SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZFB'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	1pvj	PYROGENIC EXOTOXIN B (Streptococcus pyogenes)	4 / 7	LEU A 231 GLY A 277 TYR A 276 SER A 280	None None None ZFB A 450 (-4.7A)	0.94A	4cp3A-1pvjA: undetectable 4cp3B-1pvjA: undetectable	4cp3A-1pvjA: 15.24 4cp3B-1pvjA: 15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IIL_A_RBFA401_1 (MEMBRANE LIPOPROTEIN TPN38(B))	1pvj	PYROGENIC EXOTOXIN B (Streptococcus pyogenes)	5 / 12	SER A 280 TYR A 276 ALA A 233 ILE A 261 GLY A 191	ZFB A 450 (-4.7A) None None None ZFB A 450 ( 4.1A)	1.24A	4iilA-1pvjA: undetectable	4iilA-1pvjA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB603_1 (PHIAB6 TAILSPIKE)	1pvj	PYROGENIC EXOTOXIN B (Streptococcus pyogenes)	3 / 3	VAL A 337 GLU A 126 GLU A 122	ZFB A 450 (-3.9A) None None	0.81A	5jsdB-1pvjA: 0.0 5jsdC-1pvjA: 0.0	5jsdB-1pvjA: 20.62 5jsdC-1pvjA: 20.62