SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZEN'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AQ7_B_AG2B4_1 (TRYPSINAERUGINOSIN 98-B) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 8 | HIS T 57ASP T 189SER T 195VAL T 213GLY T 216GLY T 226 | SO4 T 600 (-3.8A)ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.46A | 1aq7A-1j17T:42.9 | 1aq7A-1j17T:71.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1BCU_H_PRLH280_0 (ALPHA-THROMBIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 7 / 9 | ASP T 189ALA T 190SER T 195VAL T 213TRP T 215GLY T 216GLY T 226 | ZEN T 1 ( 3.8A)ZEN T 1 (-3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.32A | 1bcuH-1j17T:18.7 | 1bcuH-1j17T:37.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DWC_H_MITH1_1 (ALPHA-THROMBIN(LARGE SUBUNIT)) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 9 | HIS T 57ASP T 189SER T 195TRP T 215GLY T 226 | SO4 T 600 (-3.8A)ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A) | 0.37A | 1dwcH-1j17T:34.3 | 1dwcH-1j17T:37.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETR_H_MITH1_1 (EPSILON-THROMBIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 7 / 12 | HIS T 57ASP T 189SER T 195VAL T 213TRP T 215GLY T 216GLY T 226 | SO4 T 600 (-3.8A)ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.49A | 1etrH-1j17T:34.4 | 1etrH-1j17T:38.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F5L_A_AMRA301_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 8 | ASP T 189GLN T 192SER T 195VAL T 213GLY T 216GLY T 226 | ZEN T 1 ( 3.8A)NoneSO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.50A | 1f5lA-1j17T:15.2 | 1f5lA-1j17T:36.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TNL_A_TPAA900_1 (TRYPSIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 6 | ASP T 189SER T 195VAL T 213GLY T 216GLY T 226 | ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.20A | 1tnlA-1j17T:43.0 | 1tnlA-1j17T:71.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2NMZ_B_ROCB401_1 (PROTEASE) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 12 | LEU T 137GLY T 19ASP T 189GLY T 142PRO T 198ILE T 138 | NoneNoneZEN T 1 ( 3.8A)NoneNoneNone | 1.21A | 2nmzA-1j17T:undetectable | 2nmzA-1j17T:17.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 6 | ASP T 189SER T 195VAL T 213GLY T 216GLY T 226 | ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.13A | 2otvA-1j17T:43.0 | 2otvA-1j17T:71.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2P16_A_GG2A298_1 (COAGULATION FACTOR X(EC 3.4.21.6)(STUART FACTOR)(STUART-PROWERFACTOR)) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 10 / 12 | TYR T 99PHE T 174ASP T 189ALA T 190SER T 195VAL T 213TRP T 215GLY T 216GLY T 226TYR T 228 | ZEN T 1 (-3.8A)ZEN T 1 (-3.8A)ZEN T 1 ( 3.8A)ZEN T 1 (-3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A)ZEN T 1 (-3.6A) | 0.37A | 2p16A-1j17T:36.4 | 2p16A-1j17T:39.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VIN_A_505A1247_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 8 | ASP T 189GLN T 192SER T 195VAL T 213GLY T 216GLY T 226 | ZEN T 1 ( 3.8A)NoneSO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.72A | 2vinA-1j17T:14.5 | 2vinA-1j17T:36.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 11 / 12 | TYR T 99PHE T 174ASP T 189ALA T 190SER T 195VAL T 213TRP T 215GLY T 216GLY T 219GLY T 226TYR T 228 | ZEN T 1 (-3.8A)ZEN T 1 (-3.8A)ZEN T 1 ( 3.8A)ZEN T 1 (-3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-4.5A)ZEN T 1 (-3.7A)ZEN T 1 (-3.6A) | 0.40A | 2w26A-1j17T:14.3 | 2w26A-1j17T:39.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 11 | HIS T 57ASP T 189SER T 195TRP T 215GLY T 216GLY T 226 | SO4 T 600 (-3.8A)ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.29A | 3gy3A-1j17T:41.7 | 3gy3A-1j17T:71.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3L8L_D_DVAD8_0 (GRAMICIDIN D) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 3 / 3 | VAL T 227VAL T 213TRP T 215 | NoneZEN T 1 (-4.1A)ZEN T 1 (-3.4A) | 0.95A | 3l8lC-1j17T:undetectable3l8lD-1j17T:undetectable | 3l8lC-1j17T:5.123l8lD-1j17T:6.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MB5_A_SAMA301_0 (SAM-DEPENDENTMETHYLTRANSFERASE) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 12 | ILE T 212VAL T 213GLY T 44ALA T 55ILE T 73 | NoneZEN T 1 (-4.1A)NoneNoneNone | 0.97A | 3mb5A-1j17T:undetectable | 3mb5A-1j17T:21.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXF_A_4APA9_1 (CATIONIC TRYPSIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 6 | SER T 195VAL T 213TRP T 215GLY T 216GLY T 226 | SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.18A | 3rxfA-1j17T:43.1 | 3rxfA-1j17T:71.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXH_A_HSMA7_1 (CATIONIC TRYPSIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 4 / 5 | ASP T 189SER T 195VAL T 213GLY T 226 | ZEN T 1 ( 3.8A)SO4 T 600 ( 2.6A)ZEN T 1 (-4.1A)ZEN T 1 (-3.7A) | 0.24A | 3rxhA-1j17T:43.1 | 3rxhA-1j17T:71.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3W67_B_VIVB301_0 (ALPHA-TOCOPHEROLTRANSFER PROTEIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 12 | ILE T 89VAL T 213ILE T 242ILE T 47LEU T 209 | NoneZEN T 1 (-4.1A)NoneNoneNone | 1.01A | 3w67B-1j17T:undetectable | 3w67B-1j17T:21.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4HFP_D_15UD402_1 (PROTHROMBIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 12 | HIS T 57ASP T 189ALA T 190VAL T 213TRP T 215GLY T 226 | SO4 T 600 (-3.8A)ZEN T 1 ( 3.8A)ZEN T 1 (-3.8A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A) | 0.28A | 4hfpD-1j17T:34.3 | 4hfpD-1j17T:37.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 6 / 12 | HIS T 57ALA T 190VAL T 213TRP T 215GLY T 216GLY T 226 | SO4 T 600 (-3.8A)ZEN T 1 (-3.8A)ZEN T 1 (-4.1A)ZEN T 1 (-3.4A)ZEN T 1 (-3.7A)ZEN T 1 (-3.7A) | 0.72A | 4rn6B-1j17T:28.7 | 4rn6B-1j17T:37.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KBW_A_RBFA201_1 (RIBOFLAVINTRANSPORTER RIBU) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 12 | LEU T 185ASP T 189GLY T 226ASN T 224ALA T 170 | NoneZEN T 1 ( 3.8A)ZEN T 1 (-3.7A)NoneNone | 1.42A | 5kbwA-1j17T:undetectable | 5kbwA-1j17T:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KC0_A_RBFA303_1 (RIBOFLAVINTRANSPORTER RIBU) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 12 | LEU T 185ASP T 189GLY T 226ASN T 224ALA T 170 | NoneZEN T 1 ( 3.8A)ZEN T 1 (-3.7A)NoneNone | 1.41A | 5kc0A-1j17T:undetectable | 5kc0A-1j17T:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_H_PCFH604_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 8CYTOCHROME C OXIDASEPOLYPEPTIDE 5A,MITOCHONDRIAL) |
1j17 | TRYPSIN II, ANIONIC (Rattusnorvegicus) | 5 / 8 | GLY T 216VAL T 183GLY T 193SER T 195ALA T 55 | ZEN T 1 (-3.7A)NoneSO4 T 600 (-3.8A)SO4 T 600 ( 2.6A)None | 1.39A | 6hu9H-1j17T:undetectable6hu9e-1j17T:undetectable | 6hu9H-1j17T:14.696hu9e-1j17T:22.87 |